alanine has been researched along with Disease Models, Animal in 268 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Fluorouracil (5-FU)-induced intestinal mucositis is one of the most common morbidities in chemotherapy and involves the reactive oxygen species (ROS) system, apoptosis, and inflammatory cytokines." | 7.81 | Rebamipide attenuates 5-Fluorouracil-induced small intestinal mucositis in a mouse model. ( Han, SH; Kim, HJ; Kim, JH; Lee, JH; Moon, W; Park, J; Park, SJ; Song, GA, 2015) |
| "We investigated the correlation of plasma amino acid concentrations and the effects of glucosamine and fish collagen peptide (FCP) on osteoarthritis (OA)." | 7.79 | Correlation of plasma amino acid concentrations and chondroprotective effects of glucosamine and fish collagen peptide on the development of osteoarthritis. ( Imagawa, T; Matahira, Y; Minami, S; Ohnishi, A; Okamoto, Y; Osaki, T; Tsuka, T, 2013) |
| "Lewy bodies are found in Parkinson disease and related disorders and are extensively phosphorylated at Ser-129 (S129), but whether S129 phosphorylation mediates alpha-synuclein aggregation and neurotoxicity has been controversial." | 7.75 | Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease. ( Fan, Z; Feany, MB; Hyman, BT; McFarland, NR; McLean, PJ; Schwarzschild, MA; Xu, K, 2009) |
| "Results of these studies demonstrate that provision of additional NO substrate in the form of L-arginine incites prostaglandin-dependent secretory diarrhea and does not promote epithelial defense or barrier function of C." | 7.74 | Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets. ( Coccaro, MR; Foster, DM; Gookin, JL; Stauffer, SH, 2008) |
| "Previous studies by our group demonstrated a striking relationship among arginine, nitric oxide production, and salt-sensitive hypertension in the Dahl/Rapp rat." | 7.70 | Studies of arginine metabolism and salt sensitivity in the Dahl/Rapp rat models of hypertension. ( Chen, PY; Hamm, DA; Sanders, PW; Wood, PA, 1998) |
| "The early-weaned pig develops intestinal atrophy and provides a readily accessible animal model for determining the role of dietary supplementation of glutamine (Gln, a major fuel for enterocytes) in preventing intestinal damage." | 7.69 | Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs. ( Knabe, DA; Meier, SA; Wu, G, 1996) |
| "Consumption of certain product lots of L-tryptophan (LT) has been reported to be epidemiologically associated with an outbreak of eosinophilia-myalgia syndrome (EMS) in the United States." | 7.69 | Subchronic toxicity of 3-phenylamino alanine, an impurity in L-tryptophan reported to be associated with eosinophilia-myalgia syndrome. ( Hagiwara, Y; Kawase, Y; Sato, F, 1995) |
| "The aim of the study was to compare, in a rat model of congestive heart failure, the effect of captopril, a selective angiotensin-converting enzyme (ACE; EC 3." | 7.69 | Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril. ( Bralet, J; Gros, C; Lecomte, JM; Marie, C; Mossiat, C; Schwartz, JC, 1994) |
| "Epilepsy is often considered to be a progressive neurological disease, and the nature of this progression remains unclear." | 5.72 | Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes. ( Cheng, P; Jia, P; Liao, S; Meng, K; Xiao, C; Xu, R; Zhao, X; Zheng, X, 2022) |
| "Sprague-Dawley rats were used in middle cerebral artery occlusion model of stroke." | 5.62 | Post Stroke Safinamide Treatment Attenuates Neurological Damage by Modulating Autophagy and Apoptosis in Experimental Model of Stroke in Rats. ( Dinda, AK; Joshi, B; Reeta, KH; Sharma, U; Singh, D; Wasan, H, 2021) |
| "Flecainide was also potent in suppressing microglial activation in experimental autoimmune encephalomyelitis." | 5.39 | Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis. ( Bechtold, D; Chauhdry, S; Hassoon, P; Lee, W; Malpass, K; Morsali, D; Palchaudhuri, U; Piers, T; Pocock, J; Roach, A; Smith, KJ; Snell, DM, 2013) |
| "Colitis was more severe in rats subjected to neonatal or adult capsaicin treatment, but was not affected by subdiaphragmatic vagotomy." | 5.31 | Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents. ( Barada, KA; Kafrouni, MI; Khoury, CI; Mourad, FH; Nassar, CF; Saade, NE; Szabo, SS, 2001) |
| "Penicillin seizures do not cause a change in levels of GABA, but result in a decrease in glutamate within the focus." | 5.26 | Effect of amino-oxyacetic acid (AOAA) on focal penicillin seizures. ( Collins, RC; Mehta, S, 1978) |
| " We used a macaque model of repeated exposures to simian human immunodeficiency virus (SHIV) to investigate whether TAF alone or the combination of TAF and emtricitabine (FTC) can prevent vaginal infection." | 3.91 | Efficacy of Oral Tenofovir Alafenamide/Emtricitabine Combination or Single-Agent Tenofovir Alafenamide Against Vaginal Simian Human Immunodeficiency Virus Infection in Macaques. ( Babusis, D; Callebaut, C; Cong, ME; Deyounks, F; Dinh, C; García-Lerma, JG; Heneine, W; Holder, A; Johnson, R; Khalil, G; Lipscomb, J; Massud, I; McCallister, S; Nishiura, K; Pan, Y; Park, Y; Rooney, JF; Ruone, S, 2019) |
| " This study aims to determine small intestinal alanine absorption and cytokine expression in a novel model of colonic ulceration induced by electro-cautery." | 3.81 | Electrocautery-induced localized colonic injury elicits increased levels of pro-inflammatory cytokines in small bowel and decreases jejunal alanine absorption. ( Barada, K; Mourad, FH; Noutsi, B; Saadé, NE, 2015) |
| "5-Fluorouracil (5-FU)-induced intestinal mucositis is one of the most common morbidities in chemotherapy and involves the reactive oxygen species (ROS) system, apoptosis, and inflammatory cytokines." | 3.81 | Rebamipide attenuates 5-Fluorouracil-induced small intestinal mucositis in a mouse model. ( Han, SH; Kim, HJ; Kim, JH; Lee, JH; Moon, W; Park, J; Park, SJ; Song, GA, 2015) |
| "Polaprezinc (PZ), which consists of l-carnosine and zinc, is widely used to treat gastric ulcers." | 3.79 | The effect of polaprezinc on gastric mucosal protection in rats with ethanol-induced gastric mucosal damage: comparison study with rebamipide. ( Choi, HS; Chun, HJ; Jeen, YT; Keum, B; Kim, CD; Kim, ES; Lee, HS; Lee, M; Lim, JY; Ryu, HS; Seo, YS; Sul, D; Um, SH, 2013) |
| "We investigated the correlation of plasma amino acid concentrations and the effects of glucosamine and fish collagen peptide (FCP) on osteoarthritis (OA)." | 3.79 | Correlation of plasma amino acid concentrations and chondroprotective effects of glucosamine and fish collagen peptide on the development of osteoarthritis. ( Imagawa, T; Matahira, Y; Minami, S; Ohnishi, A; Okamoto, Y; Osaki, T; Tsuka, T, 2013) |
| " Following hyperpolarized [1-(13)C]pyruvate injections, pyruvate and its metabolic products, alanine and lactate, were observed in the liver of five rats with hepatocellular carcinoma and five healthy control rats." | 3.76 | T(2) relaxation times of (13)C metabolites in a rat hepatocellular carcinoma model measured in vivo using (13)C-MRS of hyperpolarized [1-(13)C]pyruvate. ( Butts Pauly, K; Hurd, R; King, R; Le Roux, P; Mayer, D; Pfefferbaum, A; Spielman, D; Tropp, J; Vasanawala, S; Yen, YF, 2010) |
| "Lewy bodies are found in Parkinson disease and related disorders and are extensively phosphorylated at Ser-129 (S129), but whether S129 phosphorylation mediates alpha-synuclein aggregation and neurotoxicity has been controversial." | 3.75 | Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease. ( Fan, Z; Feany, MB; Hyman, BT; McFarland, NR; McLean, PJ; Schwarzschild, MA; Xu, K, 2009) |
| "Results of these studies demonstrate that provision of additional NO substrate in the form of L-arginine incites prostaglandin-dependent secretory diarrhea and does not promote epithelial defense or barrier function of C." | 3.74 | Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets. ( Coccaro, MR; Foster, DM; Gookin, JL; Stauffer, SH, 2008) |
| " We show that modulation of the eNOS serine 1179 (S1179) phosphorylation site affects vascular reactivity and determines stroke size in vivo." | 3.74 | The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo. ( Atochin, DN; Ayata, C; Critchlow, JD; Dantas, AP; Huang, PL; Liu, VW; Looft-Wilson, R; Michel, T; Moskowitz, MA; Murata, T; Salomone, S; Sessa, WC; Shin, HK; Wang, A, 2007) |
| " plantarum strains were administered in ornithine transcarbamoylase-deficient Sparse-fur mice, a model of constitutive hyperammonemia, in a carbon tetrachloride rat model of chronic liver insufficiency and in a thioacetamide-induced acute liver failure mice model." | 3.74 | Control of acute, chronic, and constitutive hyperammonemia by wild-type and genetically engineered Lactobacillus plantarum in rodents. ( Demetter, P; Devière, J; Goffin, P; Gustot, T; Hols, P; Moreno, C; Nicaise, C; Prozzi, D; Quertinmont, E; Suain, V; Viaene, E, 2008) |
| "Hyperthyroidism was induced by treating rats with L-thyroxine (12 mg/L) in the drinking water for 21 days." | 3.72 | Decreased activity and expression of intestinal oligopeptide transporter PEPT1 in rats with hyperthyroidism in vivo. ( Ashida, K; Inui, K; Katsura, T; Saito, H, 2004) |
| "We investigated the effects of an intravenous load of alpha-ketoglutaric acid, ammonium (NH(4)(+)), and metabolic acidosis on plasma concentration and splanchnic and hindleg tissue exchange of glutamine, glutamate, alanine, and arginine in postabsorptive, anesthetized pigs." | 3.71 | Glutamine concentration and tissue exchange with intravenously administered alpha-ketoglutaric acid and ammonium: a dose-response study in the pig. ( Karlsson, T; Nordgren, A; Wiklund, L, 2002) |
| "Previous studies by our group demonstrated a striking relationship among arginine, nitric oxide production, and salt-sensitive hypertension in the Dahl/Rapp rat." | 3.70 | Studies of arginine metabolism and salt sensitivity in the Dahl/Rapp rat models of hypertension. ( Chen, PY; Hamm, DA; Sanders, PW; Wood, PA, 1998) |
| "Consumption of certain product lots of L-tryptophan (LT) has been reported to be epidemiologically associated with an outbreak of eosinophilia-myalgia syndrome (EMS) in the United States." | 3.69 | Subchronic toxicity of 3-phenylamino alanine, an impurity in L-tryptophan reported to be associated with eosinophilia-myalgia syndrome. ( Hagiwara, Y; Kawase, Y; Sato, F, 1995) |
| "The aim of the study was to compare, in a rat model of congestive heart failure, the effect of captopril, a selective angiotensin-converting enzyme (ACE; EC 3." | 3.69 | Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril. ( Bralet, J; Gros, C; Lecomte, JM; Marie, C; Mossiat, C; Schwartz, JC, 1994) |
| "The early-weaned pig develops intestinal atrophy and provides a readily accessible animal model for determining the role of dietary supplementation of glutamine (Gln, a major fuel for enterocytes) in preventing intestinal damage." | 3.69 | Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs. ( Knabe, DA; Meier, SA; Wu, G, 1996) |
| "Unidirectional fluxes of alanine, methionine, and Na were measured in jejunal segments from 3- to 4-wk-old normal (N) mice or mice with congenital (P) or induced (I) megacolon in the absence of electrochemical gradients." | 3.66 | Jejunal transport properties of piebald mouse model for Hirschsprung's disease. ( Cooke, AR; Cooke, HJ; Henning, HJ; Wood, JD, 1980) |
| "Alzheimer's disease is thought to be caused by increased formations of neurotoxic amyloid beta (A beta) peptides, which give rise to the hallmark amyloid plaques." | 2.45 | Development of semagacestat (LY450139), a functional gamma-secretase inhibitor, for the treatment of Alzheimer's disease. ( Dean, RA; Henley, DB; May, PC; Siemers, ER, 2009) |
| "Safinamide has neuroprotective and neurorescuing effects in MPTP-treated mice, in the rat kainic acid, and in the gerbil ischemia model." | 2.43 | Safinamide: from molecular targets to a new anti-Parkinson drug. ( Caccia, C; Calabresi, M; Curatolo, L; Faravelli, L; Fariello, RG; Maestroni, S; Maj, R; Salvati, P, 2006) |
| "In the experiment designed to provoke gastric cancer through MNU treatment with H." | 2.42 | Chemoprevention of Helicobacter pylori-associated gastric carcinogenesis in a mouse model: is it possible? ( Cho, SW; Hahm, KB; Han, SU; Kim, DY; Kim, JH; Kim, MW; Kim, YB; Lee, JS; Nahm, KT; Oh, TY; Song, YJ; Surh, YJ; Yoo, BM, 2003) |
| "Epilepsy is often considered to be a progressive neurological disease, and the nature of this progression remains unclear." | 1.72 | Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes. ( Cheng, P; Jia, P; Liao, S; Meng, K; Xiao, C; Xu, R; Zhao, X; Zheng, X, 2022) |
| "Efficacious therapeutics for Ebola virus disease are in great demand." | 1.62 | Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus. ( Bannister, R; Bavari, S; Cihlar, T; Donnelly, G; Garza, NL; Gomba, L; Iversen, PL; Kane, CD; Norris, S; Porter, DP; Steffens, J; Stuthman, KS; Van Tongeren, SA; Warren, TK; Weidner, JM; Wells, J; Zeng, X, 2021) |
| "5 folds enhancement in relative bioavailability and remarkable amplification in anti-ulcer, anti-inflammatory and the antioxidant potential of these cocrystals were observed." | 1.62 | Engineering a Remedy to Modulate and Optimize Biopharmaceutical Properties of Rebamipide by Synthesizing New Cocrystal: In Silico and Experimental Studies. ( Chadha, R; Dureja, J; Jindal, A; Karan, M; Singh, R; Tomar, S, 2021) |
| "Effective treatments for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are urgently needed." | 1.62 | Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection. ( Cai, JP; Cao, J; Chan, CC; Chan, JF; Chu, H; Jin, DY; Ong, CP; Poon, VK; Tang, K; Yang, D; Ye, ZW; Yu, CY; Yuan, S; Yuen, KY; Zhang, AJ, 2021) |
| "Skeletal muscle atrophy occurs in response to various pathophysiological stimuli, including disuse, aging, and neuromuscular disorders, mainly due to an imbalance of anabolic/catabolic signaling." | 1.62 | BCAAs and Di-Alanine supplementation in the prevention of skeletal muscle atrophy: preclinical evaluation in a murine model of hind limb unloading. ( Allegretti, M; Aramini, A; Bianchini, G; Boccanegra, B; Camerino, GM; Cappellari, O; Conte, E; De Bellis, M; De Luca, A; Mantuano, P; Pierno, S; Sanarica, F, 2021) |
| "Sprague-Dawley rats were used in middle cerebral artery occlusion model of stroke." | 1.62 | Post Stroke Safinamide Treatment Attenuates Neurological Damage by Modulating Autophagy and Apoptosis in Experimental Model of Stroke in Rats. ( Dinda, AK; Joshi, B; Reeta, KH; Sharma, U; Singh, D; Wasan, H, 2021) |
| "The continued emergence of Middle East Respiratory Syndrome (MERS) cases with a high case fatality rate stresses the need for the availability of effective antiviral treatments." | 1.56 | Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. ( Cihlar, T; Cronin, J; de Wit, E; Feldmann, F; Feldmann, H; Jordan, R; Okumura, A; Scott, D; Thomas, T, 2020) |
| "Effective therapies to treat coronavirus disease 2019 (COVID-19) are urgently needed." | 1.56 | Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2. ( Anzick, S; Barbian, K; Bosio, CM; Cihlar, T; de Wit, E; Feldmann, F; Hanley, PW; Leighton, I; Lovaglio, J; Martens, C; Meade-White, K; Munster, VJ; Okumura, A; Pérez-Pérez, L; Porter, DP; Saturday, G; Schulz, J; Schwarz, B; Scott, DP; van Doremalen, N; Williamson, BN; Yinda, CK, 2020) |
| " We found that early accumulation of KARs occurs in the DA neurons of the parkinQ311X mouse, and that chronic administration of the KAR antagonist UBP310 prevents DA neuron loss." | 1.56 | Pharmacological antagonism of kainate receptor rescues dysfunction and loss of dopamine neurons in a mouse model of human parkin-induced toxicity. ( Albanese, F; Bagnati, R; Cattaneo, S; Ciammola, A; Consalez, GG; Croci, L; Davoli, E; Di Fonzo, A; Mercatelli, D; Morari, M; Novello, S; Passafaro, M; Passoni, A; Regoni, M; Sassone, J; Serratto, GM; Taverna, S; Valtorta, F; Zanetti, L, 2020) |
| "Brivanib is an oral selective dual receptor tyrosine kinase (RTK) inhibitor of FGFRs and VEGFRs, especially VEGFR2 and FGFR1." | 1.56 | Brivanib, a multitargeted small-molecule tyrosine kinase inhibitor, suppresses laser-induced CNV in a mouse model of neovascular AMD. ( Chen, J; Ding, D; Gu, J; Li, L; Liu, D; Liu, X; Qin, B; Sang, A; Shi, Y; Tu, Y; Wu, W; Zhu, M, 2020) |
| "Gastrointestinal mucositis is a serious side effect of chemotherapy." | 1.51 | Efficacy of Azatyrosine-Phenylbutyric Hydroxamides, a Histone Deacetylase Inhibitor, on Chemotherapy-Induced Gastrointestinal Mucositis. ( Cheng, YW; Huang, SH; Huang, WK; Hung, CH; Kang, JJ; Liao, PL; Tsai, CH; Wang, HP, 2019) |
| "To determine the mucinogenic effect of dry eye (DE) treatment drugs currently in use, we compared the levels of mucin production and inflammatory cytokine expression on the ocular surfaces using a DE-induced mice model." | 1.48 | Comparison of Ocular Surface Mucin Expression After Topical Ophthalmic Drug Administration in Dry Eye-Induced Mouse Model. ( Ji, YW; Kang, HG; Kim, HC; Lee, HK; Moon, I; Noh, H; Song, JS; Yeo, A, 2018) |
| "Radiation-induced colitis is a common clinical problem associated with radiotherapy and accidental exposure to ionizing radiation." | 1.48 | Rebamipide alleviates radiation-induced colitis through improvement of goblet cell differentiation in mice. ( Jang, H; Jang, WS; Jin, YW; Kim, H; Lee, C; Lee, J; Lee, SJ; Lee, SS; Myung, H; Myung, JK; Park, S; Shim, S, 2018) |
| "Pantoprazole (5 mg/kg) was administered intraperitoneally to the PPI and PPI+R groups." | 1.48 | Additive Effects of Rebamipide Plus Proton Pump Inhibitors on the Expression of Tight Junction Proteins in a Rat Model of Gastro-Esophageal Reflux Disease. ( Choi, YK; Chung, JW; Gweon, TG; Kim, BW; Kim, CW; Kim, HG; Kim, JS; Park, JH; Park, SM, 2018) |
| "Staphylococcus aureus infections are becoming a major global health issue due to the rapid emergence of multidrug-resistant strains." | 1.48 | A D-Alanine auxotrophic live vaccine is effective against lethal infection caused by Staphylococcus aureus. ( Bou, G; Cabral, MP; García, P; Moscoso, M; Rumbo, C, 2018) |
| "Furthermore, in a mouse model of mitochondrial myopathy, we show that increased oxidative αKG flux in muscle arises from enhanced alanine synthesis and release into blood, concomitant with accelerated amino acid catabolism from protein breakdown." | 1.48 | Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations. ( Arreguin, AJ; Beal, MF; Calder, EL; Carelli, V; Chen, Q; D'Aurelio, M; Denton, TT; Gross, SS; Kirk, K; Manfredi, G; Primiano, G; Shahi, I; Shurubor, YI; Valsecchi, F; Zhao, D, 2018) |
| "Irsogladine maleate (IM) is a drug with gastric mucosal protective properties." | 1.48 | [Development of "Patient Friendly Formulations" to Counter the Side Effects of Cancer Chemotherapy]. ( Hanawa, T; Kawano, Y; Satoh, M, 2018) |
| "Safinamide (Xadago) is a novel dual-mechanism drug that has been approved in the European Union and United States as add-on treatment to levodopa in Parkinson's disease therapy." | 1.48 | Safinamide Modulates Striatal Glutamatergic Signaling in a Rat Model of Levodopa-Induced Dyskinesia. ( Brugnoli, A; Caccia, C; Gardoni, F; Keywood, C; Kulisevsky, J; Mellone, M; Melloni, E; Morari, M; Novello, S; Padoani, G; Pisanò, CA; Sosti, V; Vailati, S, 2018) |
| " Here, we show in the model system Caenorhabditis elegans that expression of the arginine-containing dipeptides, but not alanine-containing dipeptides, produces toxic phenotypes in multiple cellular contexts, including motor neurons." | 1.46 | Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans. ( Lamitina, ST; Monaghan, J; Pandey, UB; Rudich, P; Snoznik, C; Watkins, SC, 2017) |
| "Colitis was induced via an intrarectal injection of TNBS in mice." | 1.43 | Oridonin derivative ameliorates experimental colitis by inhibiting activated T-cells and translocation of nuclear factor-kappa B. ( Chen, K; Liu, QQ; Sun, YW; Wang, HL; Wang, SB; Xu, Y; Ye, Q, 2016) |
| " We found that S421 phosphorylation mitigates neurodegeneration by increasing proteasome-dependent turnover of mHTT and reducing the presence of a toxic mHTT conformer." | 1.43 | Serine 421 regulates mutant huntingtin toxicity and clearance in mice. ( Daub, AC; Finkbeiner, S; Gu, X; Humbert, S; Kratter, IH; Lau, A; Masliah, E; Osmand, A; Saudou, F; Steffan, JS; Tsvetkov, AS; Weiberth, KF; Yang, XW; Zahed, H, 2016) |
| "The most common cause of HSAN1 is due to dominant mutations in serine palmitoyl-transferase subunit 1 (SPT1)." | 1.42 | Identification of dietary alanine toxicity and trafficking dysfunction in a Drosophila model of hereditary sensory and autonomic neuropathy type 1. ( Lloyd-Evans, E; Oswald, MC; Sweeney, ST; West, RJ, 2015) |
| "MNNG-induced carcinogenesis and may also inhibit progression of cancer in rats." | 1.42 | Preventive effect of rebamipide on N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats. ( Ebi, M; Hayashi, N; Joh, T; Katano, T; Kataoka, H; Mizoshita, T; Mori, Y; Ozeki, K; Shimura, T; Tanida, S; Tatematsu, M; Tsukamoto, H; Tsukamoto, T, 2015) |
| "An unresolved debate in Alzheimer's disease (AD) is whether amyloid plaques are pathogenic, causing overt physical disruption of neural circuits, or protective, sequestering soluble forms of amyloid-β (Aβ) that initiate synaptic damage and cognitive decline." | 1.40 | Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease. ( Chiang, AC; Cirrito, JR; Fowler, SW; Jankowsky, JL; Larson, ME; Lesné, SE; Savjani, RR; Schuler, DR; Sherman, MA, 2014) |
| "This study showed that breast cancer cells tolerate and use lactate at clinically relevant concentrations in vitro (± glucose) and in vivo." | 1.39 | Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer. ( Chi, JT; Dewhirst, MW; Kennedy, KM; Landon, CD; Pizzo, S; Ribeiro, A; Richardson, R; Scarbrough, PM; Schroeder, T; Sonveaux, P; Yuan, H, 2013) |
| "Flecainide was also potent in suppressing microglial activation in experimental autoimmune encephalomyelitis." | 1.39 | Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis. ( Bechtold, D; Chauhdry, S; Hassoon, P; Lee, W; Malpass, K; Morsali, D; Palchaudhuri, U; Piers, T; Pocock, J; Roach, A; Smith, KJ; Snell, DM, 2013) |
| "A rat model of dry eye was developed by surgical removal of exorbital lacrimal glands." | 1.39 | Protection of human corneal epithelial cells from TNF-α-induced disruption of barrier function by rebamipide. ( Haruta, J; Kimura, K; Morita, Y; Orita, T; Sonoda, KH; Takeji, Y, 2013) |
| "Glycine has been shown to participate in protection from hypoxia/reoxygenation injury." | 1.39 | Effects of glycine supplementation on myocardial damage and cardiac function after severe burn. ( Liang, GP; Lv, SJ; Peng, X; Wan, QX; Wang, L; Yan, H; Zhang, Y, 2013) |
| "Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder characterized by myokymia and attacks of ataxic gait often precipitated by stress." | 1.38 | Kv1.1 knock-in ataxic mice exhibit spontaneous myokymic activity exacerbated by fatigue, ischemia and low temperature. ( Botti, FM; Brunetti, O; D'Adamo, MC; Di Giovanni, G; Gibertini, S; Imbrici, P; Mora, M; Muscat, R; Pessia, M; Pettorossi, VE; Valentino, M; Zammit, C, 2012) |
| "Classical pathological signs of Parkinson's disease (PD) include loss of dopaminergic neurons in substantia nigra (SN) and noradrenergic neurons in locus coeruleus (LC), and deposition of Lewy bodies rich in the presynaptic protein alpha-synuclein (ASYN)." | 1.36 | Selective noradrenergic vulnerability in α-synuclein transgenic mice. ( Sotiriou, E; Stefanis, L; Vassilatis, DK; Vila, M, 2010) |
| "We report the establishment of an in vivo model using the fruit fly Drosophila melanogaster to investigate the toxic effects of L-BMAA." | 1.35 | BMAA neurotoxicity in Drosophila. ( Bradley, WG; Escala, W; Papapetropoulos, S; Zhai, RG; Zhou, X, 2009) |
| "The deficits of Alzheimer's disease (AD) are believed to result, at least in part, from neurotoxicity of beta-amyloid (Abeta), a set of 38-43 amino acid fragments derived from the beta-amyloid precursor protein (APP)." | 1.35 | Long-term prevention of Alzheimer's disease-like behavioral deficits in PDAPP mice carrying a mutation in Asp664. ( Ataie, M; Banwait, S; Bredesen, DE; Galvan, V; Gorostiza, OF; Huang, W; Tang, H; Zhang, J, 2008) |
| "APPDutch transgenic (tg) mice develop cerebral amyloid angiopathy (CAA) that consists mainly of AbetaDutch40, with virtually no parenchymal amyloid plaques." | 1.34 | BACE1 and mutated presenilin-1 differently modulate Abeta40 and Abeta42 levels and cerebral amyloidosis in APPDutch transgenic mice. ( Herzig, MC; Jucker, M; Paganetti, P; Staufenbiel, M, 2007) |
| "D-mannose is an essential monosaccharide constituent of glycoproteins and glycolipids." | 1.33 | Hepatic glycogen breakdown is implicated in the maintenance of plasma mannose concentration. ( Asano, N; Miwa, I; Mizutani, T; Nakajima, H; Taguchi, T; Yabuuchi, M; Yamashita, E, 2005) |
| "Amyotrophic lateral sclerosis (ALS), a multifactorial disease characterized by diffuse motor neuron degeneration, has proven to be a difficult target for stem cell therapy." | 1.32 | Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation. ( Chen, N; Davis, CD; Garbuzova-Davis, S; Hudson, JE; Justen, EB; Lane, JC; Sanberg, PR; Saporta, S; Willing, AE; Zigova, T, 2003) |
| "Depression is characterized by a lack of "motivation" rather than a lack of "physical space" to move around." | 1.32 | Open space swimming test to index antidepressant activity. ( Alkon, DL; Sun, MK, 2003) |
| "Colitis was more severe in rats subjected to neonatal or adult capsaicin treatment, but was not affected by subdiaphragmatic vagotomy." | 1.31 | Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents. ( Barada, KA; Kafrouni, MI; Khoury, CI; Mourad, FH; Nassar, CF; Saade, NE; Szabo, SS, 2001) |
| "The present study evaluated the therapeutic effects of rebamipide alone and in combination with cimetidine on experimental gastritis established by the administration of 5 mM sodium taurocholate (TCA) for 6 months in rats." | 1.28 | Therapeutic effects of oral rebamipide and in combination with cimetidine on experimental gastritis in rats. ( Fujimura, J; Haruma, K; Kajiyama, G; Kishimoto, S; Kobayashi, H; Machino, H; Sakurai, K; Shimamoto, T; Shimizu, S; Yamasaki, K, 1992) |
| "These data suggest that intrauterine growth retardation in dogs results in fasting neonatal hypoglycemia that is due in part to reduced systemic glucose production." | 1.28 | Alterations of fasting glucose and fat metabolism in intrauterine growth-retarded newborn dogs. ( Kliegman, RM, 1989) |
| "Penicillin seizures do not cause a change in levels of GABA, but result in a decrease in glutamate within the focus." | 1.26 | Effect of amino-oxyacetic acid (AOAA) on focal penicillin seizures. ( Collins, RC; Mehta, S, 1978) |
| "Diaminopimelic acid was absent in the Legionnaires' disease bacterium peptidoglycan." | 1.26 | Fine structure of the Legionnaires' disease bacterium. In-vitro and in-vivo studies of four isolates. ( Feeley, JC; Finnerty, WR; Keel, JA, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (6.34) | 18.7374 |
| 1990's | 23 (8.58) | 18.2507 |
| 2000's | 79 (29.48) | 29.6817 |
| 2010's | 109 (40.67) | 24.3611 |
| 2020's | 40 (14.93) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 3 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Korolowicz, KE | 1 |
| Suresh, M | 1 |
| Li, B | 2 |
| Huang, X | 1 |
| Yon, C | 1 |
| Kallakury, BV | 1 |
| Lee, KP | 1 |
| Park, S | 2 |
| Kim, YW | 1 |
| Menne, S | 1 |
| Warren, TK | 2 |
| Kane, CD | 1 |
| Wells, J | 2 |
| Stuthman, KS | 1 |
| Van Tongeren, SA | 1 |
| Garza, NL | 1 |
| Donnelly, G | 2 |
| Steffens, J | 2 |
| Gomba, L | 2 |
| Weidner, JM | 2 |
| Norris, S | 1 |
| Zeng, X | 1 |
| Bannister, R | 2 |
| Cihlar, T | 5 |
| Bavari, S | 2 |
| Porter, DP | 5 |
| Iversen, PL | 1 |
| Boras, B | 1 |
| Jones, RM | 1 |
| Anson, BJ | 1 |
| Arenson, D | 1 |
| Aschenbrenner, L | 1 |
| Bakowski, MA | 1 |
| Beutler, N | 1 |
| Binder, J | 1 |
| Chen, E | 1 |
| Eng, H | 1 |
| Hammond, H | 1 |
| Hammond, J | 1 |
| Haupt, RE | 1 |
| Hoffman, R | 1 |
| Kadar, EP | 1 |
| Kania, R | 1 |
| Kimoto, E | 1 |
| Kirkpatrick, MG | 1 |
| Lanyon, L | 1 |
| Lendy, EK | 1 |
| Lillis, JR | 1 |
| Logue, J | 1 |
| Luthra, SA | 1 |
| Ma, C | 1 |
| Mason, SW | 1 |
| McGrath, ME | 1 |
| Noell, S | 1 |
| Obach, RS | 1 |
| O' Brien, MN | 1 |
| O'Connor, R | 1 |
| Ogilvie, K | 1 |
| Owen, D | 1 |
| Pettersson, M | 1 |
| Reese, MR | 1 |
| Rogers, TF | 1 |
| Rosales, R | 1 |
| Rossulek, MI | 1 |
| Sathish, JG | 1 |
| Shirai, N | 1 |
| Steppan, C | 1 |
| Ticehurst, M | 1 |
| Updyke, LW | 1 |
| Weston, S | 1 |
| Zhu, Y | 1 |
| White, KM | 1 |
| García-Sastre, A | 1 |
| Wang, J | 2 |
| Chatterjee, AK | 1 |
| Mesecar, AD | 1 |
| Frieman, MB | 1 |
| Anderson, AS | 1 |
| Allerton, C | 1 |
| Li, Q | 1 |
| Wu, X | 2 |
| Xin, M | 1 |
| Jindal, A | 1 |
| Singh, R | 1 |
| Tomar, S | 1 |
| Dureja, J | 1 |
| Karan, M | 1 |
| Chadha, R | 1 |
| Williamson, BN | 2 |
| Pérez-Pérez, L | 2 |
| Schwarz, B | 2 |
| Feldmann, F | 3 |
| Holbrook, MG | 1 |
| Singh, M | 1 |
| Lye, DS | 1 |
| Babusis, D | 3 |
| Subramanian, R | 1 |
| Haddock, E | 1 |
| Okumura, A | 3 |
| Hanley, PW | 2 |
| Lovaglio, J | 2 |
| Bosio, CM | 2 |
| Mackman, RL | 1 |
| Saturday, G | 2 |
| de Wit, E | 3 |
| Spyropoulos, F | 1 |
| Sorrentino, A | 1 |
| van der Reest, J | 1 |
| Yang, P | 1 |
| Waldeck-Weiermair, M | 1 |
| Steinhorn, B | 1 |
| Eroglu, E | 1 |
| Saeedi Saravi, SS | 1 |
| Yu, P | 1 |
| Haigis, M | 1 |
| Christou, H | 1 |
| Michel, T | 2 |
| Kerkaert, JD | 1 |
| Le Mauff, F | 1 |
| Wucher, BR | 1 |
| Beattie, SR | 1 |
| Vesely, EM | 1 |
| Sheppard, DC | 1 |
| Nadell, CD | 1 |
| Cramer, RA | 1 |
| Gao, J | 1 |
| Wu, P | 1 |
| Chi, Y | 1 |
| Xu, H | 1 |
| Zhao, Y | 3 |
| Song, N | 1 |
| Mao, Y | 1 |
| Zhao, X | 2 |
| Cheng, P | 1 |
| Xu, R | 2 |
| Meng, K | 1 |
| Liao, S | 1 |
| Jia, P | 1 |
| Zheng, X | 1 |
| Xiao, C | 1 |
| Huang, F | 1 |
| Zhang, T | 1 |
| Wang, S | 1 |
| Xu, C | 1 |
| Huang, C | 1 |
| Lin, D | 1 |
| Oishi, K | 1 |
| Yajima, Y | 1 |
| Yoshida, Y | 1 |
| Hagihara, H | 1 |
| Miyakawa, T | 1 |
| Higo-Yamamoto, S | 1 |
| Toyoda, A | 1 |
| Jin-Sil, P | 1 |
| Sun-Hee, H | 1 |
| SeungCheon, Y | 1 |
| JeongWon, C | 1 |
| Kyung-Ah, J | 1 |
| Mi-La, C | 1 |
| Sung-Hwan, P | 1 |
| Uehara, M | 1 |
| Yamazaki, H | 1 |
| Yoshikawa, N | 1 |
| Kuribara-Souta, A | 1 |
| Tanaka, H | 2 |
| Shamloo, K | 1 |
| Barbarino, A | 1 |
| Alfuraih, S | 1 |
| Sharma, A | 1 |
| Kilpeläinen, T | 1 |
| Julku, UH | 1 |
| Svarcbahs, R | 1 |
| Myöhänen, TT | 2 |
| Zhao, J | 1 |
| Han, M | 1 |
| Zhou, L | 1 |
| Liang, P | 1 |
| Wang, Y | 5 |
| Feng, S | 1 |
| Lu, H | 1 |
| Yuan, X | 1 |
| Han, K | 1 |
| Chen, X | 3 |
| Liu, S | 2 |
| Cheng, J | 1 |
| Nakayama, T | 1 |
| Tsukamoto, M | 1 |
| Watanabe, A | 1 |
| Nakamura, T | 2 |
| Yokoi, N | 2 |
| Sotozono, C | 2 |
| Kinoshita, S | 2 |
| Cronin, J | 1 |
| Jordan, R | 2 |
| Thomas, T | 1 |
| Scott, D | 1 |
| Feldmann, H | 1 |
| Maxmen, A | 1 |
| Sheahan, TP | 1 |
| Sims, AC | 1 |
| Zhou, S | 1 |
| Graham, RL | 1 |
| Pruijssers, AJ | 1 |
| Agostini, ML | 1 |
| Leist, SR | 1 |
| Schäfer, A | 1 |
| Dinnon, KH | 1 |
| Stevens, LJ | 1 |
| Chappell, JD | 1 |
| Lu, X | 1 |
| Hughes, TM | 1 |
| George, AS | 1 |
| Hill, CS | 1 |
| Montgomery, SA | 1 |
| Brown, AJ | 1 |
| Bluemling, GR | 1 |
| Natchus, MG | 1 |
| Saindane, M | 1 |
| Kolykhalov, AA | 1 |
| Painter, G | 1 |
| Harcourt, J | 1 |
| Tamin, A | 1 |
| Thornburg, NJ | 1 |
| Swanstrom, R | 1 |
| Denison, MR | 1 |
| Baric, RS | 1 |
| Soleimani Moez, A | 1 |
| H Sajedi, R | 1 |
| Pooshang Bagheri, K | 1 |
| Sabatier, JM | 1 |
| Shahbazzadeh, D | 1 |
| Basu, S | 1 |
| Mackowiak, SD | 1 |
| Niskanen, H | 1 |
| Knezevic, D | 1 |
| Asimi, V | 1 |
| Grosswendt, S | 1 |
| Geertsema, H | 1 |
| Ali, S | 1 |
| Jerković, I | 1 |
| Ewers, H | 1 |
| Mundlos, S | 1 |
| Meissner, A | 1 |
| Ibrahim, DM | 1 |
| Hnisz, D | 1 |
| Blair, C | 1 |
| Wetzel, K | 1 |
| Garza, N | 1 |
| Van Tongeren, S | 1 |
| Moreau, A | 1 |
| Bearss, J | 1 |
| Lee, E | 1 |
| Meade-White, K | 1 |
| Schulz, J | 1 |
| van Doremalen, N | 1 |
| Leighton, I | 1 |
| Yinda, CK | 1 |
| Anzick, S | 1 |
| Barbian, K | 1 |
| Martens, C | 1 |
| Scott, DP | 1 |
| Munster, VJ | 1 |
| Shuai, L | 1 |
| Wang, C | 1 |
| Liu, R | 1 |
| He, X | 1 |
| Zhang, X | 1 |
| Sun, Z | 1 |
| Shan, D | 1 |
| Ge, J | 1 |
| Wang, X | 2 |
| Hua, R | 1 |
| Zhong, G | 1 |
| Wen, Z | 1 |
| Bu, Z | 1 |
| Abdel-Wahab, BA | 1 |
| Ali, FEM | 1 |
| Alkahtani, SA | 1 |
| Alshabi, AM | 1 |
| Mahnashi, MH | 1 |
| Hassanein, EHM | 1 |
| Dobrovolny, HM | 1 |
| Regoni, M | 1 |
| Cattaneo, S | 1 |
| Mercatelli, D | 1 |
| Novello, S | 2 |
| Passoni, A | 1 |
| Bagnati, R | 1 |
| Davoli, E | 1 |
| Croci, L | 1 |
| Consalez, GG | 1 |
| Albanese, F | 1 |
| Zanetti, L | 1 |
| Passafaro, M | 1 |
| Serratto, GM | 1 |
| Di Fonzo, A | 1 |
| Valtorta, F | 1 |
| Ciammola, A | 1 |
| Taverna, S | 1 |
| Morari, M | 2 |
| Sassone, J | 2 |
| Xu, N | 1 |
| Zhang, C | 1 |
| Jing, L | 1 |
| Mou, S | 1 |
| Cao, X | 1 |
| Yu, Z | 1 |
| Altiné-Samey, R | 1 |
| Antier, D | 1 |
| Mavel, S | 1 |
| Dufour-Rainfray, D | 1 |
| Balageas, AC | 1 |
| Beaufils, E | 1 |
| Emond, P | 1 |
| Foucault-Fruchard, L | 1 |
| Chalon, S | 1 |
| Cicka, D | 1 |
| Sukhatme, VP | 1 |
| Ye, ZW | 1 |
| Yuan, S | 1 |
| Chan, JF | 1 |
| Zhang, AJ | 1 |
| Yu, CY | 1 |
| Ong, CP | 1 |
| Yang, D | 2 |
| Chan, CC | 2 |
| Tang, K | 1 |
| Cao, J | 1 |
| Poon, VK | 1 |
| Cai, JP | 1 |
| Chu, H | 1 |
| Yuen, KY | 1 |
| Jin, DY | 2 |
| Okun, JG | 2 |
| Rusu, PM | 1 |
| Chan, AY | 1 |
| Wu, Y | 1 |
| Yap, YW | 1 |
| Sharkie, T | 1 |
| Schumacher, J | 1 |
| Schmidt, KV | 1 |
| Roberts-Thomson, KM | 1 |
| Russell, RD | 1 |
| Zota, A | 1 |
| Hille, S | 1 |
| Jungmann, A | 1 |
| Maggi, L | 1 |
| Lee, Y | 1 |
| Blüher, M | 1 |
| Herzig, S | 1 |
| Keske, MA | 1 |
| Heikenwalder, M | 1 |
| Müller, OJ | 1 |
| Rose, AJ | 1 |
| Cross, RW | 1 |
| Bornholdt, ZA | 1 |
| Prasad, AN | 1 |
| Borisevich, V | 1 |
| Agans, KN | 1 |
| Deer, DJ | 1 |
| Abelson, DM | 1 |
| Kim, DH | 1 |
| Shestowsky, WS | 1 |
| Campbell, LA | 1 |
| Bunyan, E | 1 |
| Geisbert, JB | 1 |
| Fenton, KA | 1 |
| Zeitlin, L | 1 |
| Geisbert, TW | 1 |
| Naser, FJ | 1 |
| Jackstadt, MM | 1 |
| Fowle-Grider, R | 1 |
| Spalding, JL | 1 |
| Cho, K | 1 |
| Stancliffe, E | 1 |
| Doonan, SR | 1 |
| Kramer, ET | 1 |
| Yao, L | 1 |
| Krasnick, B | 1 |
| Ding, L | 1 |
| Fields, RC | 1 |
| Kaufman, CK | 1 |
| Shriver, LP | 1 |
| Johnson, SL | 1 |
| Patti, GJ | 1 |
| Yin, L | 1 |
| Zhao, H | 1 |
| Zhang, H | 1 |
| Li, Y | 2 |
| Dong, Y | 1 |
| Ju, H | 1 |
| Kong, F | 1 |
| Zhao, S | 1 |
| Wan, Y | 2 |
| Wu, W | 3 |
| Li, L | 2 |
| Zhang, J | 3 |
| Yao, X | 1 |
| Bertelsen, LB | 2 |
| Hansen, ESS | 1 |
| Sadowski, T | 1 |
| Ruf, S | 1 |
| Laustsen, C | 3 |
| Mantuano, P | 1 |
| Boccanegra, B | 1 |
| Bianchini, G | 1 |
| Conte, E | 1 |
| De Bellis, M | 1 |
| Sanarica, F | 1 |
| Camerino, GM | 1 |
| Pierno, S | 1 |
| Cappellari, O | 1 |
| Allegretti, M | 1 |
| Aramini, A | 1 |
| De Luca, A | 1 |
| Wasan, H | 1 |
| Singh, D | 1 |
| Joshi, B | 1 |
| Sharma, U | 1 |
| Dinda, AK | 1 |
| Reeta, KH | 1 |
| Ellis, AS | 1 |
| Fosnocht, AQ | 1 |
| Lucerne, KE | 1 |
| Briand, LA | 1 |
| Fan, S | 1 |
| Zhong, W | 1 |
| Zhou, X | 2 |
| Li, S | 2 |
| Tagami, S | 1 |
| Yanagida, K | 1 |
| Kodama, TS | 1 |
| Takami, M | 1 |
| Mizuta, N | 1 |
| Oyama, H | 1 |
| Nishitomi, K | 1 |
| Chiu, YW | 1 |
| Okamoto, T | 1 |
| Ikeuchi, T | 1 |
| Sakaguchi, G | 1 |
| Kudo, T | 1 |
| Matsuura, Y | 1 |
| Fukumori, A | 1 |
| Takeda, M | 1 |
| Ihara, Y | 1 |
| Okochi, M | 1 |
| Rudich, P | 1 |
| Snoznik, C | 1 |
| Watkins, SC | 1 |
| Monaghan, J | 1 |
| Pandey, UB | 1 |
| Lamitina, ST | 1 |
| Jang, H | 1 |
| Lee, J | 1 |
| Myung, JK | 1 |
| Jang, WS | 1 |
| Lee, SJ | 1 |
| Myung, H | 1 |
| Lee, C | 1 |
| Kim, H | 1 |
| Lee, SS | 1 |
| Jin, YW | 1 |
| Shim, S | 1 |
| Gweon, TG | 1 |
| Park, JH | 1 |
| Kim, BW | 1 |
| Choi, YK | 1 |
| Kim, JS | 2 |
| Park, SM | 1 |
| Kim, CW | 1 |
| Kim, HG | 1 |
| Chung, JW | 1 |
| Lin, HJ | 1 |
| Hsu, CC | 1 |
| Chio, CC | 1 |
| Tian, YF | 1 |
| Lin, MT | 1 |
| Lin, TW | 1 |
| Chang, CH | 1 |
| Chang, CP | 1 |
| Moscoso, M | 1 |
| García, P | 1 |
| Cabral, MP | 1 |
| Rumbo, C | 1 |
| Bou, G | 1 |
| Hanawa, T | 1 |
| Kawano, Y | 1 |
| Satoh, M | 1 |
| Kuang, S | 1 |
| Yang, L | 1 |
| Rao, Z | 1 |
| Zhong, Z | 1 |
| Li, J | 1 |
| Zhong, H | 1 |
| Dai, L | 1 |
| Tang, X | 1 |
| Kojima, T | 3 |
| Simsek, C | 2 |
| Igarashi, A | 2 |
| Aoki, K | 1 |
| Higa, K | 1 |
| Shimizu, T | 2 |
| Dogru, M | 2 |
| Tsubota, K | 3 |
| Shimazaki, J | 3 |
| Chen, Q | 1 |
| Kirk, K | 1 |
| Shurubor, YI | 1 |
| Zhao, D | 1 |
| Arreguin, AJ | 1 |
| Shahi, I | 1 |
| Valsecchi, F | 1 |
| Primiano, G | 1 |
| Calder, EL | 1 |
| Carelli, V | 1 |
| Denton, TT | 1 |
| Beal, MF | 2 |
| Gross, SS | 1 |
| Manfredi, G | 1 |
| D'Aurelio, M | 1 |
| Perna, AF | 1 |
| Anishchenko, E | 1 |
| Vigorito, C | 1 |
| Zacchia, M | 1 |
| Trepiccione, F | 1 |
| D'Aniello, S | 1 |
| Ingrosso, D | 1 |
| Grosenbaugh, DK | 1 |
| Ross, BM | 1 |
| Wagley, P | 1 |
| Zanelli, SA | 1 |
| Henrich, MT | 1 |
| Geibl, FF | 1 |
| Lee, B | 2 |
| Chiu, WH | 1 |
| Koprich, JB | 1 |
| Brotchie, JM | 2 |
| Timmermann, L | 1 |
| Decher, N | 1 |
| Matschke, LA | 1 |
| Oertel, WH | 1 |
| Wang, F | 2 |
| Song, ZY | 1 |
| Qu, XJ | 1 |
| Li, F | 1 |
| Zhang, L | 1 |
| Li, WB | 1 |
| Cui, SX | 1 |
| Wang, B | 1 |
| Smyl, C | 1 |
| Chen, CY | 1 |
| Li, XY | 1 |
| Huang, W | 2 |
| Zhang, HM | 1 |
| Pai, VJ | 1 |
| Kang, JX | 1 |
| Lautenschläger, I | 1 |
| Pless-Petig, G | 1 |
| Middel, P | 1 |
| de Groot, H | 1 |
| Rauen, U | 1 |
| Stojanovic, T | 1 |
| Wang, Z | 1 |
| Shen, G | 1 |
| Feng, J | 1 |
| Heissat, S | 1 |
| Harel, A | 1 |
| Um, K | 1 |
| Brunet, AS | 1 |
| Hervieu, V | 1 |
| Guillaud, O | 1 |
| Dumortier, J | 1 |
| Lachaux, A | 1 |
| Mintz, E | 1 |
| Bost, M | 1 |
| Gardoni, F | 1 |
| Kulisevsky, J | 1 |
| Brugnoli, A | 1 |
| Pisanò, CA | 1 |
| Caccia, C | 2 |
| Mellone, M | 1 |
| Melloni, E | 1 |
| Padoani, G | 1 |
| Sosti, V | 1 |
| Vailati, S | 1 |
| Keywood, C | 1 |
| Moon, I | 1 |
| Kang, HG | 1 |
| Yeo, A | 1 |
| Noh, H | 1 |
| Kim, HC | 1 |
| Song, JS | 1 |
| Ji, YW | 1 |
| Lee, HK | 1 |
| Ogawa, M | 1 |
| Nagata, T | 2 |
| Kawakita, T | 2 |
| Liao, PL | 1 |
| Huang, SH | 1 |
| Hung, CH | 1 |
| Huang, WK | 1 |
| Tsai, CH | 1 |
| Kang, JJ | 1 |
| Wang, HP | 1 |
| Cheng, YW | 1 |
| Fu, R | 2 |
| Jiang, Y | 1 |
| Zhou, J | 1 |
| Sun, CW | 1 |
| Yang, J | 1 |
| Kleschyov, AL | 1 |
| Zhuge, Z | 1 |
| Carlström, M | 1 |
| Pernow, J | 1 |
| Wajih, N | 1 |
| Isbell, TS | 1 |
| Oh, JY | 1 |
| Cabrales, P | 1 |
| Tsai, AG | 1 |
| Townes, T | 1 |
| Kim-Shapiro, DB | 1 |
| Patel, RP | 1 |
| Lundberg, JO | 1 |
| Fujimoto, A | 1 |
| Uraoka, T | 1 |
| Yahagi, N | 1 |
| Zafar, MA | 1 |
| Hammond, AJ | 1 |
| Hamaguchi, S | 1 |
| Kono, M | 1 |
| Zhao, L | 1 |
| Weiser, JN | 1 |
| Zhu, M | 1 |
| Qin, B | 1 |
| Gu, J | 1 |
| Tu, Y | 1 |
| Chen, J | 1 |
| Liu, D | 1 |
| Shi, Y | 1 |
| Liu, X | 1 |
| Sang, A | 1 |
| Ding, D | 1 |
| Cassis, P | 1 |
| Locatelli, M | 1 |
| Corna, D | 1 |
| Villa, S | 1 |
| Rottoli, D | 1 |
| Cerullo, D | 1 |
| Abbate, M | 1 |
| Remuzzi, G | 1 |
| Benigni, A | 1 |
| Zoja, C | 1 |
| Massud, I | 1 |
| Cong, ME | 1 |
| Ruone, S | 1 |
| Holder, A | 1 |
| Dinh, C | 1 |
| Nishiura, K | 1 |
| Khalil, G | 1 |
| Pan, Y | 1 |
| Lipscomb, J | 1 |
| Johnson, R | 1 |
| Deyounks, F | 1 |
| Rooney, JF | 1 |
| Park, Y | 1 |
| McCallister, S | 1 |
| Callebaut, C | 1 |
| Heneine, W | 1 |
| García-Lerma, JG | 1 |
| Kimura, K | 1 |
| Morita, Y | 1 |
| Orita, T | 1 |
| Haruta, J | 1 |
| Takeji, Y | 1 |
| Sonoda, KH | 1 |
| Morsali, D | 1 |
| Bechtold, D | 1 |
| Lee, W | 1 |
| Chauhdry, S | 1 |
| Palchaudhuri, U | 1 |
| Hassoon, P | 1 |
| Snell, DM | 1 |
| Malpass, K | 1 |
| Piers, T | 1 |
| Pocock, J | 1 |
| Roach, A | 1 |
| Smith, KJ | 1 |
| Ueta, M | 1 |
| Choi, HS | 1 |
| Lim, JY | 1 |
| Chun, HJ | 1 |
| Lee, M | 1 |
| Kim, ES | 1 |
| Keum, B | 1 |
| Seo, YS | 1 |
| Jeen, YT | 1 |
| Um, SH | 1 |
| Lee, HS | 1 |
| Kim, CD | 2 |
| Ryu, HS | 1 |
| Sul, D | 1 |
| Raz, V | 1 |
| Sterrenburg, E | 1 |
| Routledge, S | 1 |
| Venema, A | 1 |
| van der Sluijs, BM | 1 |
| Trollet, C | 1 |
| Dickson, G | 1 |
| van Engelen, BG | 1 |
| van der Maarel, SM | 1 |
| Antoniou, MN | 1 |
| Marxreiter, F | 1 |
| Ettle, B | 1 |
| May, VE | 1 |
| Esmer, H | 1 |
| Patrick, C | 1 |
| Kragh, CL | 1 |
| Klucken, J | 1 |
| Winner, B | 1 |
| Riess, O | 1 |
| Winkler, J | 1 |
| Masliah, E | 2 |
| Nuber, S | 1 |
| Paban, V | 1 |
| Manrique, C | 1 |
| Filali, M | 1 |
| Maunoir-Regimbal, S | 1 |
| Fauvelle, F | 1 |
| Alescio-Lautier, B | 1 |
| Kennedy, KM | 1 |
| Scarbrough, PM | 1 |
| Ribeiro, A | 1 |
| Richardson, R | 1 |
| Yuan, H | 1 |
| Sonveaux, P | 1 |
| Landon, CD | 1 |
| Chi, JT | 1 |
| Pizzo, S | 1 |
| Schroeder, T | 1 |
| Dewhirst, MW | 1 |
| Ohguchi, T | 1 |
| Ibrahim, OM | 1 |
| Shirasawa, T | 1 |
| Satake, Y | 1 |
| Ishida, S | 1 |
| Funahashi, Y | 2 |
| Yoshida, M | 2 |
| Yamamoto, T | 2 |
| Majima, T | 2 |
| Takai, S | 2 |
| Gotoh, M | 2 |
| Lycke, S | 1 |
| Palm, F | 1 |
| Østergaard, JA | 1 |
| Bibby, BM | 1 |
| Nørregaard, R | 2 |
| Flyvbjerg, A | 1 |
| Pedersen, M | 1 |
| Ardenkjaer-Larsen, JH | 1 |
| Beggiato, S | 1 |
| Giuliani, A | 1 |
| Sivilia, S | 1 |
| Lorenzini, L | 1 |
| Antonelli, T | 1 |
| Imbimbo, BP | 2 |
| Giardino, L | 1 |
| Calzà, L | 1 |
| Ferraro, L | 1 |
| Yang, H | 1 |
| Wang, G | 1 |
| Sun, H | 1 |
| Shu, R | 1 |
| Liu, T | 1 |
| Wang, CE | 1 |
| Liu, Z | 1 |
| Zhao, B | 1 |
| Ouyang, Z | 1 |
| Huang, J | 1 |
| Zhou, Y | 1 |
| Jiang, X | 1 |
| Xiao, Z | 1 |
| Li, XJ | 1 |
| Lai, L | 1 |
| Nakashima, T | 3 |
| Sako, N | 1 |
| Matsuda, T | 1 |
| Uematsu, N | 2 |
| Sakurai, K | 4 |
| Ishida, T | 1 |
| Savolainen, MH | 1 |
| Richie, CT | 1 |
| Harvey, BK | 1 |
| Männistö, PT | 1 |
| Maguire-Zeiss, KA | 1 |
| Arakaki, R | 2 |
| Eguchi, H | 1 |
| Yamada, A | 1 |
| Kudo, Y | 1 |
| Iwasa, A | 1 |
| Enkhmaa, T | 1 |
| Hotta, F | 1 |
| Mitamura-Aizawa, S | 1 |
| Mitamura, Y | 1 |
| Hayashi, Y | 2 |
| Ishimaru, N | 2 |
| Fowler, SW | 1 |
| Chiang, AC | 1 |
| Savjani, RR | 1 |
| Larson, ME | 1 |
| Sherman, MA | 1 |
| Schuler, DR | 1 |
| Cirrito, JR | 1 |
| Lesné, SE | 1 |
| Jankowsky, JL | 1 |
| Messmer, EM | 1 |
| Pathuri, G | 1 |
| Madka, V | 1 |
| Hedrick, AF | 1 |
| Lightfoot, SA | 1 |
| Awasthi, V | 1 |
| Cowley, BD | 1 |
| Rao, CV | 1 |
| Gali, H | 1 |
| Rodionov, RN | 1 |
| Martens-Lobenhoffer, J | 1 |
| Brilloff, S | 1 |
| Hohenstein, B | 1 |
| Jarzebska, N | 1 |
| Jabs, N | 1 |
| Kittel, A | 1 |
| Maas, R | 1 |
| Weiss, N | 1 |
| Bode-Böger, SM | 1 |
| Barada, K | 1 |
| Mourad, FH | 2 |
| Noutsi, B | 1 |
| Saadé, NE | 2 |
| Park, KD | 1 |
| Yang, XF | 1 |
| Dustrude, ET | 1 |
| Ripsch, MS | 1 |
| White, FA | 1 |
| Khanna, R | 1 |
| Kohn, H | 1 |
| Takeuchi, K | 2 |
| Takayama, S | 1 |
| Hashimoto, E | 1 |
| Itayama, M | 1 |
| Amagase, K | 1 |
| Izuhara, C | 1 |
| Tsukamoto, H | 1 |
| Mizoshita, T | 1 |
| Katano, T | 1 |
| Hayashi, N | 1 |
| Ozeki, K | 1 |
| Ebi, M | 1 |
| Shimura, T | 1 |
| Mori, Y | 2 |
| Tanida, S | 1 |
| Kataoka, H | 1 |
| Tsukamoto, T | 1 |
| Tatematsu, M | 1 |
| Joh, T | 1 |
| Peng, B | 1 |
| Su, YB | 1 |
| Li, H | 1 |
| Han, Y | 1 |
| Guo, C | 1 |
| Tian, YM | 1 |
| Peng, XX | 1 |
| Kim, HJ | 1 |
| Kim, JH | 2 |
| Moon, W | 1 |
| Park, J | 1 |
| Park, SJ | 1 |
| Song, GA | 1 |
| Han, SH | 1 |
| Lee, JH | 1 |
| Owens, GP | 1 |
| Ritchie, A | 1 |
| Rossi, A | 1 |
| Schaller, K | 1 |
| Wemlinger, S | 1 |
| Schumann, H | 1 |
| Shearer, A | 1 |
| Verkman, AS | 1 |
| Bennett, JL | 1 |
| Xu, X | 1 |
| Ma, W | 1 |
| Gao, P | 1 |
| Liang, K | 1 |
| Li, R | 2 |
| Kohata, Y | 1 |
| Nakahara, K | 1 |
| Tanigawa, T | 1 |
| Yamagami, H | 1 |
| Shiba, M | 1 |
| Watanabe, T | 1 |
| Tominaga, K | 1 |
| Fujiwara, Y | 1 |
| Arakawa, T | 3 |
| Shibamori, M | 1 |
| Sato, M | 1 |
| Sato, A | 1 |
| Yamamura, Y | 1 |
| Sasabe, H | 1 |
| Umehara, K | 1 |
| Liu, J | 1 |
| Du, J | 1 |
| Yang, Y | 1 |
| Oswald, MC | 1 |
| West, RJ | 1 |
| Lloyd-Evans, E | 1 |
| Sweeney, ST | 1 |
| Yoshihara, HA | 1 |
| Bastiaansen, JA | 1 |
| Berthonneche, C | 1 |
| Comment, A | 1 |
| Schwitter, J | 1 |
| Murakami, I | 1 |
| Zhang, R | 1 |
| Kubo, M | 1 |
| Nagaoka, K | 1 |
| Eguchi, E | 1 |
| Ogino, K | 1 |
| Vien, TN | 1 |
| Modgil, A | 1 |
| Abramian, AM | 1 |
| Jurd, R | 1 |
| Walker, J | 1 |
| Brandon, NJ | 1 |
| Terunuma, M | 1 |
| Rudolph, U | 1 |
| Maguire, J | 1 |
| Davies, PA | 1 |
| Moss, SJ | 1 |
| Liu, QQ | 1 |
| Wang, HL | 1 |
| Chen, K | 1 |
| Wang, SB | 1 |
| Xu, Y | 1 |
| Ye, Q | 1 |
| Sun, YW | 1 |
| Yamasaki, T | 1 |
| Fujinaga, M | 1 |
| Kawamura, K | 1 |
| Furutsuka, K | 1 |
| Nengaki, N | 1 |
| Shimoda, Y | 1 |
| Shiomi, S | 1 |
| Takei, M | 1 |
| Hashimoto, H | 1 |
| Yui, J | 1 |
| Wakizaka, H | 1 |
| Hatori, A | 1 |
| Xie, L | 1 |
| Kumata, K | 1 |
| Zhang, MR | 1 |
| Zakaria, S | 1 |
| El-Sisi, A | 1 |
| Taiana, M | 1 |
| Lombardi, R | 1 |
| Porretta-Serapiglia, C | 1 |
| Freschi, M | 1 |
| Bonanno, S | 2 |
| Marcuzzo, S | 2 |
| Caravello, F | 1 |
| Bendotti, C | 1 |
| Lauria, G | 1 |
| Sydow, A | 1 |
| Hochgräfe, K | 1 |
| Könen, S | 1 |
| Cadinu, D | 1 |
| Matenia, D | 1 |
| Petrova, O | 1 |
| Joseph, M | 1 |
| Dennissen, FJ | 1 |
| Mandelkow, EM | 2 |
| Abe, N | 1 |
| Funato, H | 1 |
| Hirata, A | 1 |
| Nakai, M | 1 |
| Iizuka, M | 1 |
| Shiraishi, H | 1 |
| Jobu, K | 1 |
| Yagi, Y | 1 |
| Kadota, A | 1 |
| Ogi, K | 1 |
| Yokota, J | 1 |
| Miyamura, M | 1 |
| Woods, EC | 1 |
| Nawrocki, KL | 1 |
| Suárez, JM | 1 |
| McBride, SM | 1 |
| Bushey, RT | 1 |
| Moody, MA | 1 |
| Nicely, NL | 1 |
| Haynes, BF | 1 |
| Alam, SM | 1 |
| Keir, ST | 1 |
| Bentley, RC | 1 |
| Roy Choudhury, K | 1 |
| Gottlin, EB | 1 |
| Campa, MJ | 1 |
| Liao, HX | 1 |
| Patz, EF | 1 |
| Bonnard, E | 1 |
| Poras, H | 1 |
| Fournié-Zaluski, MC | 2 |
| Roques, BP | 2 |
| Nagai, N | 1 |
| Ito, Y | 1 |
| Okamoto, N | 1 |
| Shimomura, Y | 1 |
| Kratter, IH | 1 |
| Zahed, H | 1 |
| Lau, A | 1 |
| Tsvetkov, AS | 1 |
| Daub, AC | 1 |
| Weiberth, KF | 1 |
| Gu, X | 2 |
| Saudou, F | 1 |
| Humbert, S | 1 |
| Yang, XW | 2 |
| Osmand, A | 2 |
| Steffan, JS | 2 |
| Finkbeiner, S | 2 |
| Nielsen, PM | 1 |
| Qi, H | 1 |
| Mikkelsen, E | 1 |
| Kristensen, ML | 1 |
| Stødkilde-Jørgensen, H | 1 |
| Miki, T | 1 |
| Zwingman, TA | 1 |
| Wakamori, M | 1 |
| Lutz, CM | 1 |
| Cook, SA | 1 |
| Hosford, DA | 1 |
| Herrup, K | 1 |
| Fletcher, CF | 1 |
| Frankel, WN | 1 |
| Letts, VA | 1 |
| Nagai, K | 1 |
| Doi, T | 1 |
| Ohshiro, T | 1 |
| Sunazuka, T | 1 |
| Tomoda, H | 1 |
| Takahashi, T | 3 |
| Omura, S | 1 |
| Spilman, P | 1 |
| Lessard, P | 1 |
| Sattavat, M | 1 |
| Bush, C | 1 |
| Tousseyn, T | 1 |
| Huang, EJ | 1 |
| Giles, K | 1 |
| Golde, T | 1 |
| Das, P | 1 |
| Fauq, A | 1 |
| Prusiner, SB | 1 |
| Dearmond, SJ | 2 |
| Nicaise, C | 1 |
| Prozzi, D | 1 |
| Viaene, E | 1 |
| Moreno, C | 1 |
| Gustot, T | 1 |
| Quertinmont, E | 1 |
| Demetter, P | 1 |
| Suain, V | 1 |
| Goffin, P | 1 |
| Devière, J | 1 |
| Hols, P | 1 |
| Albers, MJ | 1 |
| Bok, R | 1 |
| Chen, AP | 1 |
| Cunningham, CH | 1 |
| Zierhut, ML | 1 |
| Zhang, VY | 1 |
| Kohler, SJ | 1 |
| Tropp, J | 2 |
| Hurd, RE | 1 |
| Yen, YF | 2 |
| Nelson, SJ | 2 |
| Vigneron, DB | 2 |
| Kurhanewicz, J | 2 |
| Okamoto, R | 1 |
| Tsuchiya, K | 1 |
| Nemoto, Y | 1 |
| Akiyama, J | 1 |
| Kanai, T | 1 |
| Watanabe, M | 1 |
| Sotiriou, E | 1 |
| Vassilatis, DK | 1 |
| Vila, M | 1 |
| Stefanis, L | 1 |
| Beirowski, B | 1 |
| Babetto, E | 1 |
| Gilley, J | 1 |
| Mazzola, F | 1 |
| Conforti, L | 1 |
| Janeckova, L | 1 |
| Magni, G | 1 |
| Ribchester, RR | 1 |
| Coleman, MP | 1 |
| Schroeder, A | 1 |
| Fahrenholz, F | 1 |
| Schmitt, U | 1 |
| Vaslin, A | 1 |
| Puyal, J | 1 |
| Clarke, PG | 1 |
| Vail, DM | 1 |
| Thamm, DH | 1 |
| Reiser, H | 1 |
| Ray, AS | 1 |
| Wolfgang, GH | 1 |
| Watkins, WJ | 1 |
| Henne, IN | 1 |
| Hawkins, MJ | 1 |
| Kurzman, ID | 1 |
| Jeraj, R | 1 |
| Vanderhoek, M | 1 |
| Plaza, S | 1 |
| Anderson, C | 1 |
| Wessel, MA | 1 |
| Robat, C | 1 |
| Lawrence, J | 1 |
| Tumas, DB | 1 |
| Maciejak, P | 1 |
| Szyndler, J | 1 |
| Turzyńska, D | 1 |
| Sobolewska, A | 1 |
| Taracha, E | 1 |
| Skórzewska, A | 1 |
| Lehner, M | 1 |
| Bidziński, A | 1 |
| Hamed, A | 1 |
| Wisłowska-Stanek, A | 1 |
| Płaźnik, A | 1 |
| McFarland, NR | 1 |
| Fan, Z | 1 |
| Xu, K | 1 |
| Schwarzschild, MA | 1 |
| Feany, MB | 2 |
| Hyman, BT | 1 |
| McLean, PJ | 1 |
| Henley, DB | 1 |
| May, PC | 1 |
| Dean, RA | 1 |
| Siemers, ER | 1 |
| D'Ambrosi, N | 1 |
| Finocchi, P | 1 |
| Apolloni, S | 1 |
| Cozzolino, M | 1 |
| Ferri, A | 1 |
| Padovano, V | 1 |
| Pietrini, G | 1 |
| Carrì, MT | 1 |
| Volonté, C | 1 |
| Qian, J | 1 |
| Ren, X | 1 |
| Zhang, P | 1 |
| Jones, WK | 1 |
| Molkentin, JD | 1 |
| Fan, GC | 1 |
| Kranias, EG | 1 |
| Escala, W | 1 |
| Papapetropoulos, S | 1 |
| Bradley, WG | 2 |
| Zhai, RG | 1 |
| Greiner, ER | 1 |
| Mishra, R | 1 |
| Kodali, R | 1 |
| Thompson, LM | 1 |
| Wetzel, R | 1 |
| Graham, DR | 1 |
| Sidhu, A | 1 |
| Le Roux, P | 1 |
| Mayer, D | 1 |
| King, R | 1 |
| Spielman, D | 1 |
| Butts Pauly, K | 1 |
| Pfefferbaum, A | 1 |
| Vasanawala, S | 1 |
| Hurd, R | 1 |
| Hendrickson, LM | 1 |
| Zhao-Shea, R | 1 |
| Pang, X | 1 |
| Gardner, PD | 1 |
| Tapper, AR | 1 |
| Miyoshi, Y | 1 |
| Hamase, K | 1 |
| Okamura, T | 1 |
| Konno, R | 1 |
| Kasai, N | 1 |
| Tojo, Y | 1 |
| Zaitsu, K | 1 |
| Yang, WW | 1 |
| Sidman, RL | 1 |
| Taksir, TV | 1 |
| Treleaven, CM | 1 |
| Fidler, JA | 1 |
| Cheng, SH | 1 |
| Dodge, JC | 1 |
| Shihabuddin, LS | 1 |
| Vargas, MR | 1 |
| Johnson, DA | 1 |
| Johnson, JA | 1 |
| Zucca, I | 1 |
| Mastropietro, A | 1 |
| de Rosbo, NK | 1 |
| Cavalcante, P | 1 |
| Tartari, S | 1 |
| Preite, L | 1 |
| Mantegazza, R | 1 |
| Bernasconi, P | 1 |
| Peterson, LW | 1 |
| Kijek, P | 1 |
| Mitchell, S | 1 |
| Hilfinger, J | 1 |
| Breitenbach, J | 1 |
| Borysko, K | 1 |
| Drach, JC | 1 |
| Kashemirov, BA | 1 |
| McKenna, CE | 1 |
| Hu, S | 1 |
| Balakrishnan, A | 1 |
| Bok, RA | 1 |
| Anderton, B | 1 |
| Larson, PE | 1 |
| Goga, A | 1 |
| Szego, ÉM | 1 |
| Gerhardt, E | 1 |
| Outeiro, TF | 1 |
| Kermer, P | 1 |
| Sauer, SW | 1 |
| Merle, U | 1 |
| Opp, S | 1 |
| Haas, D | 1 |
| Hoffmann, GF | 1 |
| Stremmel, W | 1 |
| das Neves Duarte, JM | 1 |
| Kulak, A | 1 |
| Gholam-Razaee, MM | 1 |
| Cuenod, M | 1 |
| Gruetter, R | 1 |
| Do, KQ | 1 |
| Liang, H | 1 |
| Ward, WF | 1 |
| Jang, YC | 1 |
| Bhattacharya, A | 1 |
| Bokov, AF | 1 |
| Jernigan, A | 1 |
| Richardson, A | 1 |
| Van Remmen, H | 1 |
| Lattanzi, R | 1 |
| Sacerdote, P | 1 |
| Franchi, S | 1 |
| Canestrelli, M | 1 |
| Miele, R | 1 |
| Barra, D | 1 |
| Visentin, S | 1 |
| DeNuccio, C | 1 |
| Porreca, F | 1 |
| De Felice, M | 1 |
| Guida, F | 1 |
| Luongo, L | 1 |
| de Novellis, V | 1 |
| Maione, S | 1 |
| Negri, L | 1 |
| Gohil, P | 1 |
| Thakkar, H | 1 |
| Gohil, U | 1 |
| Deshpande, S | 1 |
| Wang, YJ | 1 |
| Huang, P | 1 |
| Ung, A | 1 |
| Blendy, JA | 1 |
| Liu-Chen, LY | 1 |
| Duncan, GE | 1 |
| Koller, BH | 1 |
| Moy, SS | 1 |
| Cotella, D | 1 |
| Hernandez-Enriquez, B | 1 |
| Pan, Z | 1 |
| Leveille, J | 1 |
| Link, CD | 1 |
| Oddo, S | 1 |
| Sesti, F | 1 |
| D'Onofrio, G | 1 |
| Panza, F | 1 |
| Frisardi, V | 1 |
| Solfrizzi, V | 1 |
| Paroni, G | 1 |
| Cascavilla, L | 1 |
| Seripa, D | 1 |
| Pilotto, A | 1 |
| Bajsarowicz, K | 1 |
| Ahn, M | 1 |
| Ackerman, L | 1 |
| Dearmond, BN | 1 |
| Carlson, G | 1 |
| Busche, MA | 1 |
| Henning, HA | 1 |
| Reichwald, J | 1 |
| Staufenbiel, M | 2 |
| Sakmann, B | 1 |
| Konnerth, A | 1 |
| Brunetti, O | 1 |
| Imbrici, P | 1 |
| Botti, FM | 1 |
| Pettorossi, VE | 1 |
| D'Adamo, MC | 1 |
| Valentino, M | 1 |
| Zammit, C | 1 |
| Mora, M | 1 |
| Gibertini, S | 1 |
| Di Giovanni, G | 1 |
| Muscat, R | 1 |
| Pessia, M | 1 |
| Xu, ZH | 1 |
| Yang, Q | 1 |
| Feng, B | 1 |
| Liu, SB | 1 |
| Zhang, N | 1 |
| Xing, JH | 1 |
| Li, XQ | 1 |
| Wu, YM | 1 |
| Gao, GD | 1 |
| Zhao, MG | 1 |
| Saheki, T | 1 |
| Inoue, K | 1 |
| Ono, H | 1 |
| Katsura, N | 1 |
| Yokogawa, M | 1 |
| Yoshidumi, Y | 1 |
| Furuie, S | 1 |
| Kuroda, E | 1 |
| Ushikai, M | 1 |
| Asakawa, A | 1 |
| Inui, A | 1 |
| Eto, K | 1 |
| Kadowaki, T | 1 |
| Sinasac, DS | 1 |
| Yamamura, K | 2 |
| Kobayashi, K | 3 |
| Imaeda, H | 1 |
| Fujimoto, T | 1 |
| Takahashi, K | 1 |
| Kasumi, E | 1 |
| Fujiyama, Y | 2 |
| Andoh, A | 1 |
| Ohnishi, A | 1 |
| Osaki, T | 1 |
| Matahira, Y | 1 |
| Tsuka, T | 1 |
| Imagawa, T | 1 |
| Okamoto, Y | 1 |
| Minami, S | 1 |
| Zhang, Y | 1 |
| Lv, SJ | 1 |
| Yan, H | 1 |
| Wang, L | 1 |
| Liang, GP | 1 |
| Wan, QX | 1 |
| Peng, X | 1 |
| Collins, LV | 1 |
| Kristian, SA | 1 |
| Weidenmaier, C | 1 |
| Faigle, M | 1 |
| Van Kessel, KP | 1 |
| Van Strijp, JA | 1 |
| Götz, F | 1 |
| Neumeister, B | 1 |
| Peschel, A | 1 |
| Hahm, KB | 1 |
| Song, YJ | 1 |
| Oh, TY | 1 |
| Lee, JS | 1 |
| Surh, YJ | 1 |
| Kim, YB | 1 |
| Yoo, BM | 1 |
| Han, SU | 1 |
| Nahm, KT | 1 |
| Kim, MW | 1 |
| Kim, DY | 1 |
| Cho, SW | 1 |
| Geracitano, R | 1 |
| Paolucci, E | 1 |
| Prisco, S | 1 |
| Guatteo, E | 1 |
| Zona, C | 2 |
| Longone, P | 2 |
| Ammassari-Teule, M | 1 |
| Bernardi, G | 2 |
| Berretta, N | 1 |
| Mercuri, NB | 1 |
| Satoh, J | 1 |
| Tsujikawa, T | 1 |
| Bamba, T | 1 |
| Chung, YH | 1 |
| Joo, KM | 1 |
| Kim, MJ | 1 |
| Cha, CI | 1 |
| Van Damme, P | 1 |
| Leyssen, M | 1 |
| Callewaert, G | 1 |
| Robberecht, W | 1 |
| Van Den Bosch, L | 1 |
| Sun, MK | 1 |
| Alkon, DL | 1 |
| Garbuzova-Davis, S | 1 |
| Willing, AE | 1 |
| Zigova, T | 1 |
| Saporta, S | 1 |
| Justen, EB | 1 |
| Lane, JC | 1 |
| Hudson, JE | 1 |
| Chen, N | 1 |
| Davis, CD | 1 |
| Sanberg, PR | 1 |
| Kuo, JJ | 1 |
| Schonewille, M | 1 |
| Siddique, T | 1 |
| Schults, AN | 1 |
| Bär, PR | 1 |
| Anelli, R | 1 |
| Heckman, CJ | 1 |
| Kroese, AB | 1 |
| Turner, BJ | 1 |
| Lopes, EC | 1 |
| Cheema, SS | 1 |
| Pieri, M | 1 |
| Gaetti, C | 1 |
| Spalloni, A | 1 |
| Cavalcanti, S | 1 |
| Mercuri, N | 1 |
| Hartemann-Heurtier, A | 1 |
| Mars, LT | 1 |
| Bercovici, N | 1 |
| Desbois, S | 1 |
| Cambouris, C | 1 |
| Piaggio, E | 1 |
| Zappulla, J | 1 |
| Saoudi, A | 1 |
| Liblau, RS | 1 |
| Kirkinezos, IG | 1 |
| Hernandez, D | 1 |
| Moraes, CT | 1 |
| Malaisse, WJ | 1 |
| Ladriere, L | 1 |
| Verbruggen, I | 1 |
| Willem, R | 1 |
| Mahoney, DJ | 1 |
| Rodriguez, C | 1 |
| Devries, M | 1 |
| Yasuda, N | 1 |
| Tarnopolsky, MA | 1 |
| Horwitz, AH | 1 |
| Ammons, WS | 1 |
| Bauer, RJ | 1 |
| Dedrick, R | 1 |
| Nadell, R | 1 |
| Williams, RE | 1 |
| Liu, PS | 1 |
| Zhang, TP | 1 |
| Gui, T | 1 |
| Stafford, DW | 1 |
| Monahan, PE | 1 |
| Ashida, K | 1 |
| Katsura, T | 1 |
| Saito, H | 1 |
| Inui, K | 1 |
| Zheng, C | 1 |
| Nennesmo, I | 1 |
| Fadeel, B | 1 |
| Henter, JI | 1 |
| Taguchi, T | 1 |
| Yamashita, E | 1 |
| Mizutani, T | 1 |
| Nakajima, H | 1 |
| Yabuuchi, M | 1 |
| Asano, N | 1 |
| Miwa, I | 1 |
| Lo Bianco, C | 1 |
| Schneider, BL | 1 |
| Bauer, M | 1 |
| Sajadi, A | 1 |
| Brice, A | 1 |
| Iwatsubo, T | 1 |
| Aebischer, P | 1 |
| Cabin, DE | 1 |
| Gispert-Sanchez, S | 1 |
| Murphy, D | 1 |
| Auburger, G | 1 |
| Myers, RR | 1 |
| Nussbaum, RL | 1 |
| Okayama, M | 1 |
| Tsubouchi, R | 1 |
| Nishio, H | 1 |
| Kato, S | 1 |
| Mangalam, AK | 1 |
| Khare, M | 1 |
| Krco, CJ | 1 |
| Rodriguez, M | 1 |
| David, CS | 1 |
| Frasier, M | 2 |
| Walzer, M | 1 |
| McCarthy, L | 1 |
| Magnuson, D | 1 |
| Lee, JM | 1 |
| Haas, C | 1 |
| Kahle, P | 1 |
| Wolozin, B | 2 |
| Poon, HF | 1 |
| Shreve, N | 1 |
| Calabrese, V | 1 |
| Butterfield, DA | 1 |
| Alexander, JJ | 1 |
| Zwingmann, C | 1 |
| Quigg, R | 1 |
| Sfaello, I | 1 |
| Baud, O | 1 |
| Arzimanoglou, A | 1 |
| Gressens, P | 1 |
| Hiratsuka, T | 1 |
| Futagami, S | 1 |
| Tatsuguchi, A | 1 |
| Suzuki, K | 1 |
| Shinji, Y | 1 |
| Kusunoki, M | 1 |
| Shinoki, K | 1 |
| Nishigaki, H | 1 |
| Fujimori, S | 1 |
| Wada, K | 1 |
| Miyake, K | 1 |
| Gudis, K | 1 |
| Tsukui, T | 1 |
| Sakamoto, C | 1 |
| Nakamura, M | 1 |
| Matsumoto, T | 1 |
| Atsuda, K | 1 |
| Hibi, N | 1 |
| Matsui, H | 1 |
| Yamada, H | 1 |
| Tsuchimoto, K | 1 |
| Maeda, T | 1 |
| Nagamoto, H | 1 |
| Kumakura, T | 1 |
| Takai, M | 1 |
| Mori, T | 1 |
| Fogg, MH | 1 |
| Kaur, A | 1 |
| Cho, YG | 1 |
| Carta, M | 1 |
| Mameli, M | 1 |
| Valenzuela, CF | 1 |
| Uyama, E | 1 |
| Hino, H | 1 |
| Araki, K | 1 |
| Takeya, M | 1 |
| Uchino, M | 1 |
| Neugebauer, V | 1 |
| Li, Z | 1 |
| Zhou, C | 1 |
| Gu, B | 1 |
| Frankel, FR | 1 |
| Maj, R | 2 |
| Calabresi, M | 1 |
| Maestroni, S | 1 |
| Faravelli, L | 1 |
| Curatolo, L | 1 |
| Salvati, P | 2 |
| Fariello, RG | 2 |
| Laharie, D | 1 |
| Ménard, S | 1 |
| Asencio, C | 1 |
| Vidal-Martinez, T | 1 |
| Rullier, A | 1 |
| Zerbib, F | 1 |
| Candalh, C | 1 |
| Mégraud, F | 2 |
| Heyman, M | 2 |
| Matysiak-Budnik, T | 2 |
| Sundaram, U | 1 |
| Wisel, S | 1 |
| Coon, S | 1 |
| Steinhilb, ML | 1 |
| Dias-Santagata, D | 1 |
| Mulkearns, EE | 1 |
| Shulman, JM | 1 |
| Biernat, J | 1 |
| Atochin, DN | 1 |
| Wang, A | 1 |
| Liu, VW | 1 |
| Critchlow, JD | 1 |
| Dantas, AP | 1 |
| Looft-Wilson, R | 1 |
| Murata, T | 1 |
| Salomone, S | 1 |
| Shin, HK | 1 |
| Ayata, C | 1 |
| Moskowitz, MA | 1 |
| Sessa, WC | 1 |
| Huang, PL | 1 |
| Herzig, MC | 1 |
| Paganetti, P | 1 |
| Jucker, M | 1 |
| San Miguel Hernández, A | 1 |
| Inglada-Galiana, L | 1 |
| García Iglesias, R | 1 |
| Alonso Castillejos, N | 1 |
| Martín Gil, FJ | 1 |
| Marini, JC | 1 |
| Erez, A | 1 |
| Castillo, L | 1 |
| Nicholas, PC | 1 |
| Kim, D | 1 |
| Crews, FT | 1 |
| Macdonald, JM | 1 |
| Gookin, JL | 1 |
| Foster, DM | 1 |
| Coccaro, MR | 1 |
| Stauffer, SH | 1 |
| Kohashi, M | 1 |
| Kabashi, E | 1 |
| Agar, JN | 1 |
| Hong, Y | 1 |
| Taylor, DM | 1 |
| Minotti, S | 1 |
| Figlewicz, DA | 1 |
| Durham, HD | 1 |
| Lee, JK | 1 |
| Shin, JH | 1 |
| Suh, J | 1 |
| Choi, IS | 1 |
| Ryu, KS | 1 |
| Gwag, BJ | 1 |
| Tóth, B | 1 |
| Leonhard-Marek, S | 1 |
| Hedrich, HJ | 1 |
| Breves, G | 1 |
| Takeuchi, Y | 1 |
| Takahashi, M | 1 |
| Fuchikami, J | 1 |
| Galvan, V | 1 |
| Gorostiza, OF | 1 |
| Banwait, S | 1 |
| Ataie, M | 1 |
| Tang, H | 1 |
| Bredesen, DE | 1 |
| Craan, AG | 1 |
| Vinay, P | 1 |
| Lemieux, G | 1 |
| Gougoux, A | 1 |
| Sidhu, GS | 1 |
| Narasimharao, KL | 1 |
| Rani, VU | 1 |
| Sarkar, AK | 1 |
| Chakravarti, RN | 1 |
| Mitra, SK | 1 |
| Cooke, HJ | 1 |
| Henning, HJ | 1 |
| Wood, JD | 1 |
| Cooke, AR | 1 |
| Yebras, M | 1 |
| Salvadó, J | 1 |
| Arola, L | 1 |
| Remesar, X | 1 |
| Segués, T | 1 |
| Leichus, LS | 1 |
| Goldhill, JM | 1 |
| Long, JD | 1 |
| Percy, WH | 1 |
| Shaw, RD | 1 |
| Donovan, V | 1 |
| Burakoff, R | 1 |
| Bralet, J | 1 |
| Marie, C | 1 |
| Mossiat, C | 1 |
| Lecomte, JM | 1 |
| Gros, C | 1 |
| Schwartz, JC | 1 |
| Sato, F | 1 |
| Hagiwara, Y | 1 |
| Kawase, Y | 1 |
| McNulty, PH | 1 |
| Sinusas, AJ | 1 |
| Shi, CQ | 1 |
| Dione, D | 1 |
| Young, LH | 1 |
| Cline, GC | 1 |
| Shulman, GI | 1 |
| Gonzalez, W | 1 |
| Beslot, F | 1 |
| Laboulandine, I | 1 |
| Michel, JB | 1 |
| Andrikopoulos, S | 1 |
| Proietto, J | 1 |
| Wu, G | 1 |
| Meier, SA | 1 |
| Knabe, DA | 1 |
| Zea-Iriarte, WL | 1 |
| Makiyama, K | 1 |
| Goto, S | 1 |
| Murase, K | 1 |
| Urata, Y | 1 |
| Sekine, I | 1 |
| Hara, K | 1 |
| Kondo, T | 1 |
| Watanabe, S | 1 |
| Wang, XE | 1 |
| Hirose, M | 1 |
| Yoshizawa, T | 1 |
| Iwazaki, R | 1 |
| Oide, H | 1 |
| Kitamura, T | 1 |
| Miwa, H | 1 |
| Miyazaki, A | 1 |
| Sato, N | 1 |
| Balteskard, L | 1 |
| Unneberg, K | 1 |
| Mjaaland, M | 1 |
| Sager, G | 1 |
| Jenssen, TG | 1 |
| Revhaug, A | 1 |
| Nonaka, M | 1 |
| Yoshimine, T | 1 |
| Kohmura, E | 1 |
| Wakayama, A | 1 |
| Yamashita, T | 1 |
| Hayakawa, T | 1 |
| Wood, PA | 1 |
| Hamm, DA | 1 |
| Chen, PY | 1 |
| Sanders, PW | 1 |
| Yoshikawa, T | 1 |
| Tarnawski, A | 2 |
| Hong, KW | 1 |
| Kim, KE | 1 |
| Rhim, BY | 1 |
| Lee, WS | 1 |
| Yamane, T | 1 |
| Nakatani, H | 1 |
| Matsumoto, H | 1 |
| Iwata, Y | 1 |
| Kikuoka, N | 1 |
| Klivenyi, P | 1 |
| Ferrante, RJ | 1 |
| Matthews, RT | 1 |
| Bogdanov, MB | 1 |
| Klein, AM | 1 |
| Andreassen, OA | 1 |
| Mueller, G | 1 |
| Wermer, M | 1 |
| Kaddurah-Daouk, R | 1 |
| Pevarello, P | 1 |
| Varasi, M | 1 |
| McArthur, RA | 1 |
| Ogawa, T | 1 |
| Sugidachi, A | 1 |
| Naganuma, H | 1 |
| Asai, F | 1 |
| Moroni, F | 1 |
| Cozzi, A | 1 |
| Peruginelli, F | 1 |
| Carpenedo, R | 1 |
| Pellegrini-Giampietro, DE | 1 |
| Mariotti, R | 1 |
| Bentivoglio, M | 1 |
| de Mascarel, A | 1 |
| Abely, M | 1 |
| Mayo, K | 1 |
| Kishimoto, S | 2 |
| Haruma, K | 2 |
| Tari, A | 1 |
| Nakano, M | 1 |
| Nakagawa, Y | 1 |
| Campbell, BG | 1 |
| Wootton, JA | 1 |
| MacLeod, JN | 1 |
| Minor, RR | 1 |
| Yao, FS | 1 |
| Caserta, MT | 1 |
| Wyrwicz, AM | 1 |
| Takagaki, M | 1 |
| Powell, W | 1 |
| Sood, A | 1 |
| Spielvogel, BF | 1 |
| Hosmane, NS | 1 |
| Kirihata, M | 1 |
| Ono, K | 1 |
| Masunaga, SI | 1 |
| Kinashi, Y | 1 |
| Miyatake, SI | 1 |
| Hashimoto, N | 1 |
| Barada, KA | 1 |
| Kafrouni, MI | 1 |
| Khoury, CI | 1 |
| Szabo, SS | 1 |
| Nassar, CF | 1 |
| Silverdale, MA | 1 |
| Crossman, AR | 1 |
| Nordgren, A | 1 |
| Karlsson, T | 1 |
| Wiklund, L | 1 |
| Collins, RC | 1 |
| Mehta, S | 1 |
| Keel, JA | 1 |
| Finnerty, WR | 1 |
| Feeley, JC | 1 |
| Johnston, DG | 1 |
| Alberti, KG | 1 |
| Cács, C | 1 |
| Wapnir, RA | 2 |
| Lifshitz, F | 2 |
| McBride, WJ | 1 |
| Aprison, MH | 1 |
| Kusano, K | 1 |
| Fujimura, J | 1 |
| Machino, H | 1 |
| Shimamoto, T | 1 |
| Kobayashi, H | 1 |
| Shimizu, S | 1 |
| Kajiyama, G | 1 |
| Yamasaki, K | 1 |
| Sher, PK | 1 |
| Zdanowicz, MM | 1 |
| Teichberg, S | 1 |
| Spencer, PS | 1 |
| Roy, DN | 1 |
| Ludolph, A | 1 |
| Hugon, J | 1 |
| Dwivedi, MP | 1 |
| Schaumburg, HH | 1 |
| Kliegman, RM | 1 |
| Snider, GL | 1 |
| Hayes, JA | 1 |
| Franzblau, C | 1 |
| Kagan, HM | 1 |
| Stone, PS | 1 |
| Korthy, AL | 1 |
| Craig, CR | 1 |
| Hartman, ER | 1 |
| Cohen, AI | 1 |
| McDaniel, M | 1 |
| Orr, H | 1 |
| van Berkel, TJ | 1 |
| Koster, JF | 1 |
| Hülsmann, WC | 1 |
| Buxton, BH | 1 |
| Stewart, DA | 1 |
| Murray-Lyon, IM | 1 |
| Curzon, G | 1 |
| Williams, R | 1 |
| Lubs, H | 1 |
| Machill, G | 1 |
| Haufe, U | 1 |
| Haufe, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Outcome of Patients With COVID-19 Pneumonia Treated With Corticosteroids and Colchicine in Colombia[NCT04654416] | 301 participants (Actual) | Observational | 2020-03-20 | Completed | |||
| Open-label Study to Assess the Safety of REMdesivir-HU as Eligible Novel therapY for Moderate and Severe Covid-19 Patients[NCT04610541] | Phase 3 | 2,000 participants (Anticipated) | Interventional | 2020-10-12 | Active, not recruiting | ||
| Antiviral Activity and Safety of Remdesivir in Bangladeshi Patients With Severe Coronavirus Disease (COVID-19): An Open Label, Multi-Center, Randomized Controlled Trial[NCT04596839] | Phase 2 | 60 participants (Actual) | Interventional | 2020-09-04 | Completed | ||
| A Multi Center Randomized Open Label Trial on the Safety and Efficacy of Chloroquine for the Treatment of Hospitalized Adults With Laboratory Confirmed SARS-CoV-2 Infection in Vietnam[NCT04328493] | Phase 2 | 10 participants (Actual) | Interventional | 2020-04-07 | Completed | ||
| Multicenter, Retrospective Study of the Effects of Remdesivir in the Treatment of Severe Covid-19 Infections.[NCT04365725] | 84 participants (Actual) | Observational | 2020-05-05 | Completed | |||
| Pilot Study on Cytokine Filtration in COVID-19 ARDS (CytokCOVID19)[NCT04361526] | 40 participants (Anticipated) | Interventional | 2020-04-17 | Recruiting | |||
| STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis[NCT05603702] | Phase 1 | 24 participants (Anticipated) | Interventional | 2023-03-17 | Recruiting | ||
| Longitudinal Assessment of Autonomic and Sensory Nervous System in ALS[NCT05747937] | 100 participants (Anticipated) | Interventional | 2021-05-15 | Recruiting | |||
| Hyperpolarized 13-C Pyruvate MRI Surveillance of Multiple Cancers[NCT05697406] | Phase 1/Phase 2 | 25 participants (Anticipated) | Interventional | 2024-02-01 | Not yet recruiting | ||
| A Phase 1 Ascending-dose Study to Assess the Safety and Tolerability and Imaging Potential of Hyperpolarized Pyruvate (13C) Injection in Subjects With Prostate Cancer[NCT01229618] | Phase 1 | 31 participants (Actual) | Interventional | 2010-10-31 | Completed | ||
| Dietary Supplement N-acetylcysteine (NAC) as a Novel Complementary Medicine to Improve Cognitive Disfunction in Schizophrenia[NCT01885338] | Phase 1 | 26 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| Study of the Effect of Glutamine Supplementation on Chemotherapy Induced Toxicities in Breast Cancer Patients- A Prospective, Randomised, Single Blind, Three Arm, Phase Four Prevention Trial[NCT00772824] | Phase 4 | 23 participants (Actual) | Interventional | 2007-12-31 | Completed | ||
| Sport Therapy for Contrasting the Deterioration of Muscle Oxidative Metabolism in Patients Affected by Amyotrophic Lateral Sclerosis (ALS) - Project ME_E_SLA[NCT02548663] | 30 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| Quantifying Fatigue of the Respiratory and Swallowing Musculature in Patients With Amyotrophic Lateral Sclerosis[NCT04468191] | 0 participants (Actual) | Interventional | 2021-02-10 | Withdrawn (stopped due to COVID-19 pandemic restrictions for data collection) | |||
| The Role of Moderate Aerobic Exercise as Determined by Cardiopulmonary Exercise Testing in ALS[NCT03326622] | 48 participants (Actual) | Interventional | 2013-07-01 | Completed | |||
| "An Observational, Prospective, Multinational, Multicentre Study Comparing the Effectiveness of Safinamide, Rasagiline and Other Standard Of Care as Add-On Therapy to Levodopa (L-Dopa) in Parkinson's Disease (Pd) Fluctuating Patients"[NCT03994328] | 1,235 participants (Actual) | Observational | 2019-12-03 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for alanine and Disease Models, Animal
| Article | Year |
|---|---|
The contributions of metabolomics in the discovery of new therapeutic targets in Alzheimer's disease.
Topics: Alanine; Alzheimer Disease; Animals; Arginine; Aspartic Acid; Biomarkers; Disease Models, Animal; Gl | 2021 |
Development of semagacestat (LY450139), a functional gamma-secretase inhibitor, for the treatment of Alzheimer's disease.
Topics: Alanine; Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Azepines; Cholinesterase | 2009 |
Advances in the identification of γ-secretase inhibitors for the treatment of Alzheimer's disease.
Topics: Alanine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor | 2012 |
Chemoprevention of Helicobacter pylori-associated gastric carcinogenesis in a mouse model: is it possible?
Topics: Alanine; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cyto | 2003 |
Safinamide: from molecular targets to a new anti-Parkinson drug.
Topics: Alanine; Animals; Antiparkinson Agents; Benzylamines; Brain Ischemia; Disease Models, Animal; Gerbil | 2006 |
Rebamipide: overview of its mechanisms of action and efficacy in mucosal protection and ulcer healing.
Topics: Alanine; Animals; Anti-Ulcer Agents; Clinical Trials as Topic; Disease Models, Animal; Gastric Mucos | 1998 |
Carbohydrate metabolism in liver disease.
Topics: Alanine; Alcoholism; Animals; Blood Glucose; Carbohydrate Metabolism; Disease Models, Animal; Fastin | 1976 |
261 other studies available for alanine and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Combination Treatment with the Vimentin-Targeting Antibody hzVSF and Tenofovir Suppresses Woodchuck Hepatitis Virus Infection in Woodchucks.
Topics: Alanine; Animals; Antibodies, Monoclonal, Humanized; Antiviral Agents; Disease Models, Animal; Drug | 2021 |
Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus.
Topics: Adenosine Monophosphate; Administration, Intravenous; Aerosols; Alanine; Animals; Antiviral Agents; | 2021 |
Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19.
Topics: Adenosine Monophosphate; Alanine; Animals; Chlorocebus aethiops; Coronavirus 229E, Human; Coronaviru | 2021 |
Strengthened rebamipide ocular nanoformulation to effectively treat corneal alkali burns in mice through the HMGB1 signaling pathway.
Topics: Alanine; Animals; Antioxidants; Blotting, Western; Burns, Chemical; Chickens; Chorioallantoic Membra | 2021 |
Engineering a Remedy to Modulate and Optimize Biopharmaceutical Properties of Rebamipide by Synthesizing New Cocrystal: In Silico and Experimental Studies.
Topics: Alanine; Animals; Biological Availability; Biological Products; Carrageenan; Chemical Engineering; C | 2021 |
Subcutaneous remdesivir administration prevents interstitial pneumonia in rhesus macaques inoculated with SARS-CoV-2.
Topics: Adenosine Monophosphate; Administration, Cutaneous; Alanine; Animals; Antiviral Agents; COVID-19 Dru | 2022 |
Metabolomic and transcriptomic signatures of chemogenetic heart failure.
Topics: Alanine; Amino Acids; Animals; Cardiomyopathy, Dilated; Dependovirus; Disease Models, Animal; Heart | 2022 |
An Alanine Aminotransferase Is Required for Biofilm-Specific Resistance of Aspergillus fumigatus to Echinocandin Treatment.
Topics: Alanine; Alanine Transaminase; Animals; Antifungal Agents; Aspergillus fumigatus; Biofilms; Disease | 2022 |
LY450139 Inhibited Ti-Particle-Induced Bone Dissolution via Suppressing Notch and NF-κB Signaling Pathways.
Topics: Alanine; Animals; Azepines; Bone Resorption; Disease Models, Animal; Mice; Mice, Inbred C57BL; NF-ka | 2022 |
Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes.
Topics: Alanine; Animals; Anticonvulsants; Asparagine; Citrates; Creatine; Creatinine; Disease Models, Anima | 2022 |
NMR-based metabolomic analysis for the effects of moxibustion on imiquimod-induced psoriatic mice.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Cytokines; Disease Models, Animal; Glucose; Histidine; | 2023 |
Metabolic profiles of saliva in male mouse models of chronic sleep disorders induced by psychophysiological stress.
Topics: Alanine; Animals; Chronic Disease; Disease Models, Animal; Fabaceae; Male; Metabolome; Mice; Psychop | 2023 |
Immune modulation by rebamipide in a mouse model of Sjogren's syndrome via T and B cell regulation.
Topics: Alanine; Animals; B-Lymphocytes, Regulatory; Cytokines; Disease Models, Animal; Immunomodulation; Mi | 2019 |
Correlation among body composition and metabolic regulation in a male mouse model of Cushing's syndrome.
Topics: Adipocytes, White; Adipose Tissue; Adipose Tissue, White; Adrenal Cortex Hormones; Alanine; Alanine | 2020 |
Graft Versus Host Disease-Associated Dry Eye: Role of Ocular Surface Mucins and the Effect of Rebamipide, a Mucin Secretagogue.
Topics: Administration, Ophthalmic; Alanine; Animals; Antioxidants; Bone Marrow Transplantation; CA-125 Anti | 2019 |
Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease.
Topics: Aging; Alanine; alpha-Synuclein; Amino Acid Substitution; Animals; Behavior, Animal; Disease Models, | 2019 |
TAF and TDF attenuate liver fibrosis through NS5ATP9, TGFβ1/Smad3, and NF-κB/NLRP3 inflammasome signaling pathways.
Topics: Adenine; Alanine; Animals; Antiviral Agents; Carbon Tetrachloride; Disease Models, Animal; DNA-Bindi | 2020 |
Rebamipide promotes lacrimal duct epithelial cell survival via protecting barrier function.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cell Survival; Cells, Cultured; Disease Models, Animal; Electri | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
More than 80 clinical trials launch to test coronavirus treatments.
Topics: Adenosine Monophosphate; Alanine; Animals; Anti-HIV Agents; Betacoronavirus; China; Chloroquine; Cli | 2020 |
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
Topics: Adenosine Monophosphate; Alanine; Animals; Antibiotic Prophylaxis; Antiviral Agents; Betacoronavirus | 2020 |
Novel Mutant Phospholipase D from
Topics: Alanine; Amino Acid Substitution; Animals; Arthropod Proteins; Disease Models, Animal; Histidine; Im | 2020 |
Unblending of Transcriptional Condensates in Human Repeat Expansion Disease.
Topics: Alanine; Animals; Base Sequence; Disease Models, Animal; DNA Repeat Expansion; Homeodomain Proteins; | 2020 |
Remdesivir (GS-5734) Is Efficacious in Cynomolgus Macaques Infected With Marburg Virus.
Topics: Adenosine Monophosphate; Alanine; Animals; Antimetabolites; Antiviral Agents; Disease Models, Animal | 2020 |
Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2.
Topics: Adenosine Monophosphate; Alanine; Animals; Betacoronavirus; Bronchoalveolar Lavage Fluid; Coronaviru | 2020 |
Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice.
Topics: Adaptation, Physiological; Adenosine Monophosphate; Administration, Intranasal; Alanine; Animals; Be | 2020 |
Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways.
Topics: Alanine; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; | 2020 |
Quantifying the effect of remdesivir in rhesus macaques infected with SARS-CoV-2.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections | 2020 |
Pharmacological antagonism of kainate receptor rescues dysfunction and loss of dopamine neurons in a mouse model of human parkin-induced toxicity.
Topics: Alanine; Animals; Disease Models, Animal; Dopaminergic Neurons; Down-Regulation; Female; GluK2 Kaina | 2020 |
Protective effect and mechanism of rebamipide on NSAIDs associated small bowel injury.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Claudin-1; Cytokines; Diclofenac; Disease | 2021 |
Available drugs and supplements for rapid deployment for treatment of COVID-19.
Topics: Adenosine Monophosphate; Alanine; Animals; COVID-19; COVID-19 Drug Treatment; Disease Models, Animal | 2021 |
Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antibodies, Viral; Antiviral Agents; COVID-19; COVID-19 D | 2021 |
Liver alanine catabolism promotes skeletal muscle atrophy and hyperglycaemia in type 2 diabetes.
Topics: Alanine; Alanine Transaminase; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, An | 2021 |
Combination therapy protects macaques against advanced Marburg virus disease.
Topics: Adenosine Monophosphate; Alanine; Animals; Antibodies, Monoclonal; Antibodies, Viral; Disease Models | 2021 |
Isotope tracing in adult zebrafish reveals alanine cycling between melanoma and liver.
Topics: Aging; Alanine; Animals; Animals, Genetically Modified; Cell Tracking; Disease Models, Animal; Gluco | 2021 |
Remdesivir Alleviates Acute Kidney Injury by Inhibiting the Activation of NLRP3 Inflammasome.
Topics: Acute Kidney Injury; Adenosine Monophosphate; Alanine; Animals; Anti-Inflammatory Agents; Cells, Cul | 2021 |
Brivanib alaninate inhibited dengue virus proliferation through VEGFR2/AMPK pathway.
Topics: Alanine; AMP-Activated Protein Kinases; Animals; Antiviral Agents; Cells, Cultured; Dengue; Dengue V | 2021 |
Hyperpolarized pyruvate to measure the influence of PKM2 activation on glucose metabolism in the healthy kidney.
Topics: Alanine; Animals; Bicarbonates; Disease Models, Animal; Enzyme Activation; Glucose; Glycolysis; Hema | 2021 |
BCAAs and Di-Alanine supplementation in the prevention of skeletal muscle atrophy: preclinical evaluation in a murine model of hind limb unloading.
Topics: Alanine; Amino Acids, Branched-Chain; Animals; Dipeptides; Disease Models, Animal; Hindlimb Suspensi | 2021 |
Post Stroke Safinamide Treatment Attenuates Neurological Damage by Modulating Autophagy and Apoptosis in Experimental Model of Stroke in Rats.
Topics: Alanine; Animals; Apoptosis; Autophagy; Benzylamines; Brain; Cytokines; Disease Models, Animal; Infa | 2021 |
Disruption of GluA2 phosphorylation potentiates stress responsivity.
Topics: Alanine; Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors | 2017 |
Development and Properties of Valine-Alanine based Antibody-Drug Conjugates with Monomethyl Auristatin E as the Potent Payload.
Topics: Alanine; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Di | 2017 |
Semagacestat Is a Pseudo-Inhibitor of γ-Secretase.
Topics: Alanine; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; An | 2017 |
Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans.
Topics: Age Factors; Alanine; Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Caenorhabdi | 2017 |
Rebamipide alleviates radiation-induced colitis through improvement of goblet cell differentiation in mice.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cell Differentiation; Cell Proliferation; Colitis; Colon; Disea | 2018 |
Additive Effects of Rebamipide Plus Proton Pump Inhibitors on the Expression of Tight Junction Proteins in a Rat Model of Gastro-Esophageal Reflux Disease.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Alanine; Animals; Anti-Ulcer Agents; Disease Models, Animal | 2018 |
Gamma-Secretase Inhibitors Attenuate Neurotrauma and Neurogenic Acute Lung Injury in Rats by Rescuing the Accumulation of Hypertrophic Microglia.
Topics: Acute Lung Injury; Alanine; Amyloid Precursor Protein Secretases; Animals; Azepines; Blood-Brain Bar | 2017 |
A D-Alanine auxotrophic live vaccine is effective against lethal infection caused by Staphylococcus aureus.
Topics: Alanine; Animals; Antibodies, Bacterial; Bacteremia; Cells, Cultured; Cross Reactions; Disease Model | 2018 |
[Development of "Patient Friendly Formulations" to Counter the Side Effects of Cancer Chemotherapy].
Topics: Administration, Oral; Alanine; Animals; Antineoplastic Agents; Cell Communication; Cyclic AMP; Disea | 2018 |
Effects of Ginkgo Biloba Extract on A53T α-Synuclein Transgenic Mouse Models of Parkinson's Disease.
Topics: Alanine; alpha-Synuclein; Animals; Antiparkinson Agents; Disease Models, Animal; Dopamine Plasma Mem | 2018 |
The Role of 2% Rebamipide Eye Drops Related to Conjunctival Differentiation in Superoxide Dismutase-1 (Sod1) Knockout Mice.
Topics: Alanine; Animals; Antioxidants; Biomarkers; Cell Differentiation; Conjunctiva; Disease Models, Anima | 2018 |
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
Topics: Adaptation, Physiological; Alanine; Animals; Disease Models, Animal; DNA, Mitochondrial; Energy Meta | 2018 |
Zebrafish, a Novel Model System to Study Uremic Toxins: The Case for the Sulfur Amino Acid Lanthionine.
Topics: Alanine; Animals; Disease Models, Animal; Organogenesis; Sulfides; Toxins, Biological; Uremia; Xenob | 2018 |
The Role of Kainate Receptors in the Pathophysiology of Hypoxia-Induced Seizures in the Neonatal Mouse.
Topics: Alanine; Animals; Animals, Newborn; Disease Models, Animal; Disease Susceptibility; Electroencephalo | 2018 |
A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson's disease-like pathology in neurons and glia.
Topics: Alanine; alpha-Synuclein; Animals; Calcium-Binding Proteins; Disease Models, Animal; Endopeptidase K | 2018 |
M10, a novel derivative of Myricetin, prevents ulcerative colitis and colorectal tumor through attenuating robust endoplasmic reticulum stress.
Topics: Alanine; Animals; Anticarcinogenic Agents; Colitis, Ulcerative; Colon; Colorectal Neoplasms; Disease | 2018 |
Suppression of Postprandial Blood Glucose Fluctuations by a Low-Carbohydrate, High-Protein, and High-Omega-3 Diet via Inhibition of Gluconeogenesis.
Topics: Alanine; Alanine Transaminase; Animals; Blood Glucose; Carbon Isotopes; Diabetes Mellitus, Experimen | 2018 |
Cold Storage Injury to Rat Small-bowel Transplants-Beneficial Effect of a Modified HTK Solution.
Topics: Alanine; Animals; Cell Hypoxia; Cold Ischemia; Disease Models, Animal; Glucose; Glycine; Humans; Int | 2018 |
Metabolic Response in Rabbit Urine to Occurrence and Relief of Unilateral Ureteral Obstruction.
Topics: Acetic Acid; Alanine; Analysis of Variance; Animals; Biomarkers; Citric Acid; Creatinine; Disease Mo | 2018 |
Evaluation of the accuracy of exchangeable copper and relative exchangeable copper (REC) in a mouse model of Wilson's disease.
Topics: Adenosine Triphosphatases; Alanine; Animals; Aspartate Aminotransferases; Bilirubin; Biomarkers; Cop | 2018 |
Safinamide Modulates Striatal Glutamatergic Signaling in a Rat Model of Levodopa-Induced Dyskinesia.
Topics: Alanine; Animals; Antiparkinson Agents; Benzylamines; Corpus Striatum; Disease Models, Animal; Dopam | 2018 |
Comparison of Ocular Surface Mucin Expression After Topical Ophthalmic Drug Administration in Dry Eye-Induced Mouse Model.
Topics: Administration, Topical; Alanine; Animals; Anti-Inflammatory Agents; Cyclosporine; Disease Models, A | 2018 |
The Effect of Rebamipide Ophthalmic Solution on Cytokine and Mucin Secretion in Culture of Conjunctival Epithelial Cells From the Cu, Zn-Superoxide Dismutase-1 (SOD-1) Knock-Down Mouse.
Topics: Alanine; Animals; Antioxidants; Cells, Cultured; Conjunctiva; Conjunctival Diseases; Copper; Cytokin | 2019 |
Efficacy of Azatyrosine-Phenylbutyric Hydroxamides, a Histone Deacetylase Inhibitor, on Chemotherapy-Induced Gastrointestinal Mucositis.
Topics: Alanine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Disease Models, Animal; Gene Expr | 2019 |
Rebamipide ophthalmic solution modulates the ratio of T helper cell 17/regulatory T cells in dry eye disease mice.
Topics: Alanine; Animals; Conjunctiva; Cornea; Cytokines; Disease Models, Animal; Dry Eye Syndromes; Female; | 2019 |
Hemoglobin β93 Cysteine Is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell.
Topics: Alanine; Amino Acid Substitution; Animals; beta-Globins; Biological Transport; Blood Platelets; Cyst | 2019 |
Rebamipide solution as a submucosal injection material for possible prevention of gastric stenosis after endoscopic submucosal dissection.
Topics: Alanine; Animals; Anti-Ulcer Agents; Disease Models, Animal; Endoscopic Mucosal Resection; Gastric M | 2019 |
Identification of Pneumococcal Factors Affecting Pneumococcal Shedding Shows that the
Topics: Alanine; Animals; Animals, Newborn; Bacterial Proteins; Bacterial Shedding; Disease Models, Animal; | 2019 |
Brivanib, a multitargeted small-molecule tyrosine kinase inhibitor, suppresses laser-induced CNV in a mouse model of neovascular AMD.
Topics: Alanine; Angiogenesis Inhibitors; Animals; Cell Movement; Cell Proliferation; Choroidal Neovasculari | 2020 |
Addition of cyclic angiotensin-(1-7) to angiotensin-converting enzyme inhibitor therapy has a positive add-on effect in experimental diabetic nephropathy.
Topics: Alanine; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Type 2 | 2019 |
Efficacy of Oral Tenofovir Alafenamide/Emtricitabine Combination or Single-Agent Tenofovir Alafenamide Against Vaginal Simian Human Immunodeficiency Virus Infection in Macaques.
Topics: Adenine; Alanine; Animals; Anti-HIV Agents; Chemoprevention; Disease Models, Animal; Disease Transmi | 2019 |
Protection of human corneal epithelial cells from TNF-α-induced disruption of barrier function by rebamipide.
Topics: Adherens Junctions; Alanine; Animals; Antioxidants; beta Catenin; Cadherins; Cell Line; Disease Mode | 2013 |
Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis.
Topics: Alanine; Animals; Benzylamines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; | 2013 |
Rebamipide suppresses PolyI:C-stimulated cytokine production in human conjunctival epithelial cells.
Topics: Alanine; Animals; Antioxidants; Conjunctiva; Conjunctivitis, Allergic; Cytokines; Disease Models, An | 2013 |
The effect of polaprezinc on gastric mucosal protection in rats with ethanol-induced gastric mucosal damage: comparison study with rebamipide.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Carnosin | 2013 |
Nuclear entrapment and extracellular depletion of PCOLCE is associated with muscle degeneration in oculopharyngeal muscular dystrophy.
Topics: Age Factors; Alanine; Animals; Cell Nucleolus; Cells, Cultured; Collagen; Disease Models, Animal; Do | 2013 |
Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice.
Topics: Alanine; alpha-Synuclein; Animals; Anxiety; Avoidance Learning; Cell Count; Disease Models, Animal; | 2013 |
Therapeutic and preventive effects of methylene blue on Alzheimer's disease pathology in a transgenic mouse model.
Topics: Administration, Oral; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Avoidance Learning | 2014 |
Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer.
Topics: Adult; Aged; Alanine; Animals; Breast Neoplasms; Cell Death; Cell Hypoxia; Cell Line, Tumor; Coumari | 2013 |
The effects of 2% rebamipide ophthalmic solution on the tear functions and ocular surface of the superoxide dismutase-1 (sod1) knockout mice.
Topics: Alanine; Animals; Conjunctiva; Disease Models, Animal; Dose-Response Relationship, Drug; Dry Eye Syn | 2013 |
Intravesical application of rebamipide suppresses bladder inflammation in a rat cystitis model.
Topics: Administration, Intravesical; Alanine; Animals; Cystitis; Disease Models, Animal; Female; Quinolones | 2014 |
High altitude may alter oxygen availability and renal metabolism in diabetics as measured by hyperpolarized [1-(13)C]pyruvate magnetic resonance imaging.
Topics: Alanine; Altitude; Altitude Sickness; Animals; Atmospheric Pressure; Bicarbonates; Blood Glucose; Di | 2014 |
CHF5074 and LY450139 sub-acute treatments differently affect cortical extracellular glutamate levels in pre-plaque Tg2576 mice.
Topics: Alanine; Alzheimer Disease; Animals; Azepines; Cyclopropanes; Disease Models, Animal; Extracellular | 2014 |
Species-dependent neuropathology in transgenic SOD1 pigs.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modif | 2014 |
Novel submicronized rebamipide liquid with moderate viscosity: significant effects on oral mucositis in animal models.
Topics: Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Cautery; Disease Models, Animal; Drug Car | 2014 |
The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse.
Topics: Alanine; alpha-Synuclein; Animals; Autophagy; Brain; Brain Diseases; Cell Line, Transformed; Disease | 2014 |
Anti-inflammatory effects of rebamipide eyedrop administration on ocular lesions in a murine model of primary Sjögren's syndrome.
Topics: Administration, Ophthalmic; Alanine; Animals; Anti-Inflammatory Agents; Cells, Cultured; Disease Mod | 2014 |
Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease.
Topics: Alanine; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; An | 2014 |
[New therapeutic options for dry eye].
Topics: Alanine; Animals; Anti-Ulcer Agents; Cornea; Disease Models, Animal; Dry Eye Syndromes; Female; Huma | 2014 |
Evaluation of (99m)Tc-probestin SPECT as a novel technique for noninvasive imaging of kidney aminopeptidase N expression.
Topics: Alanine; Animals; CD13 Antigens; Disease Models, Animal; Female; Genotype; Immunohistochemistry; Kid | 2014 |
Intravesical application of rebamipide promotes urothelial healing in a rat cystitis model.
Topics: Administration, Intravesical; Alanine; Animals; Cystitis; Disease Models, Animal; Female; Quinolones | 2014 |
Role of alanine:glyoxylate aminotransferase 2 in metabolism of asymmetric dimethylarginine in the settings of asymmetric dimethylarginine overload and bilateral nephrectomy.
Topics: Acute Kidney Injury; Alanine; Animals; Arginine; Biomarkers; Blotting, Western; Disease Models, Anim | 2014 |
Electrocautery-induced localized colonic injury elicits increased levels of pro-inflammatory cytokines in small bowel and decreases jejunal alanine absorption.
Topics: Alanine; Animals; Colitis; Colon; Cytokines; Disease Models, Animal; Duodenum; Electrocoagulation; I | 2015 |
Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lacosamid
Topics: Acetamides; Alanine; Analgesics; Animals; Anticonvulsants; Benzylamines; Cells, Cultured; Cerebral C | 2015 |
Effect of rebamipide on gastric bleeding and ulcerogenic responses induced by aspirin plus clopidogrel under stimulation of acid secretion in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Aspirin; Clopidogrel; Disease Models, Animal; Gastric Acid; Gas | 2014 |
Preventive effect of rebamipide on N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats.
Topics: Adenocarcinoma; Alanine; Animals; Antioxidants; Carcinogenesis; Carcinogens; Disease Models, Animal; | 2015 |
Exogenous alanine and/or glucose plus kanamycin kills antibiotic-resistant bacteria.
Topics: Alanine; Animals; Anti-Bacterial Agents; Bacteria; Disease Models, Animal; Dose-Response Relationshi | 2015 |
Rebamipide attenuates 5-Fluorouracil-induced small intestinal mucositis in a mouse model.
Topics: Alanine; Animals; Anti-Ulcer Agents; Antimetabolites, Antineoplastic; Apoptosis; Disease Models, Ani | 2015 |
Mutagenesis of the aquaporin 4 extracellular domains defines restricted binding patterns of pathogenic neuromyelitis optica IgG.
Topics: Alanine; Animals; Antibodies, Monoclonal; Aquaporin 4; Autoantibodies; Cell Separation; CHO Cells; C | 2015 |
Rebamipide suppresses TNF-α mediated inflammation in vitro and attenuates the severity of dermatitis in mice.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Transformed; Dermatitis, Aller | 2015 |
Rebamipide Alters the Esophageal Microbiome and Reduces the Incidence of Barrett's Esophagus in a Rat Model.
Topics: Alanine; Animals; Anti-Ulcer Agents; Barrett Esophagus; Clostridium; Disease Models, Animal; Enteroc | 2015 |
Rebamipide does not interfere with the antitumor effect of radiotherapy or chemotherapy in human oral tumor-bearing nude mice.
Topics: Alanine; Animals; Antineoplastic Agents; Antioxidants; Carcinoma, Squamous Cell; Cell Line, Tumor; C | 2015 |
Phosphorylation of TRPV1 by cyclin-dependent kinase 5 promotes TRPV1 surface localization, leading to inflammatory thermal hyperalgesia.
Topics: Alanine; Animals; Calcium; Cells, Cultured; Cyclin-Dependent Kinase 5; Disease Models, Animal; Freun | 2015 |
Identification of dietary alanine toxicity and trafficking dysfunction in a Drosophila model of hereditary sensory and autonomic neuropathy type 1.
Topics: Alanine; Animals; Animals, Genetically Modified; Diet; Disease Models, Animal; Drosophila; Endoplasm | 2015 |
An intact small animal model of myocardial ischemia-reperfusion: Characterization of metabolic changes by hyperpolarized 13C MR spectroscopy.
Topics: Alanine; Animals; Bicarbonates; Carbon Isotopes; Disease Models, Animal; Hemodynamics; Inflammation; | 2015 |
Rebamipide suppresses mite-induced asthmatic responses in NC/Nga mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Alanine; Allergens; Animals; Antigens, Dermatophagoides; Antioxidants; | 2015 |
Compromising the phosphodependent regulation of the GABAAR β3 subunit reproduces the core phenotypes of autism spectrum disorders.
Topics: Alanine; Animals; Autism Spectrum Disorder; Behavior, Animal; Biotinylation; Cell Membrane; Dendriti | 2015 |
Oridonin derivative ameliorates experimental colitis by inhibiting activated T-cells and translocation of nuclear factor-kappa B.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Cytokines; Disease Models | 2016 |
Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study.
Topics: Alanine; alpha-Synuclein; Animals; Corpus Striatum; Disease Models, Animal; Disease Progression; Exc | 2016 |
Rebamipide retards CCl4-induced hepatic fibrosis in rats: Possible role for PGE2.
Topics: Alanine; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Carbo | 2016 |
ALS mouse model SOD1G93A displays early pathology of sensory small fibers associated to accumulation of a neurotoxic splice variant of peripherin.
Topics: Alanine; Alternative Splicing; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Cell | 2016 |
Age-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD.
Topics: Age Factors; Aging; Alanine; Alzheimer Disease; Animals; Astrocytes; Cognition Disorders; Cytokines; | 2016 |
[Evaluation of Gastric Mucosal Injury Model Animals of Rebamipide Formulation--Study of Therapeutic Equivalence].
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Disease Models, Animal | 2016 |
The Clostridium difficile Dlt Pathway Is Controlled by the Extracytoplasmic Function Sigma Factor σV in Response to Lysozyme.
Topics: Alanine; Animals; Bacterial Proteins; Carrier Proteins; Cell Wall; Clostridioides difficile; Cricetu | 2016 |
A Therapeutic Antibody for Cancer, Derived from Single Human B Cells.
Topics: Alanine; Animals; Antibodies, Monoclonal; Autoantibodies; B-Lymphocytes; Cell Line, Tumor; Cell Prol | 2016 |
Preventive and alleviative effects of the dual enkephalinase inhibitor (Denki) PL265 in a murine model of neuropathic pain.
Topics: Alanine; Animals; Biphenyl Compounds; Body Weight; Disease Models, Animal; Hyperalgesia; Male; Mice; | 2016 |
Size effect of rebamipide ophthalmic nanodispersions on its therapeutic efficacy for corneal wound healing.
Topics: Alanine; Animals; Antioxidants; Cell Line; Corneal Injuries; Disease Models, Animal; Epithelium, Cor | 2016 |
Serine 421 regulates mutant huntingtin toxicity and clearance in mice.
Topics: Alanine; Animals; Aspartic Acid; Behavior, Animal; Chromosomes, Artificial, Bacterial; Disease Model | 2016 |
In situ lactate dehydrogenase activity: a novel renal cortical imaging biomarker of tubular injury?
Topics: Acute Kidney Injury; Alanine; Animals; Bicarbonates; Biomarkers; Carbon Isotopes; Disease Models, An | 2017 |
Two novel alleles of tottering with distinct Ca(v)2.1 calcium channel neuropathologies.
Topics: Alanine; Animals; Animals, Newborn; Calbindins; Calcium Channels, N-Type; Cells, Cultured; Cysteine; | 2008 |
Synthesis and biological evaluation of a focused library of beauveriolides.
Topics: Alanine; Amino Acids; Animals; Atherosclerosis; Combinatorial Chemistry Techniques; Depsipeptides; D | 2008 |
A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains.
Topics: Administration, Oral; Alanine; Amyloid Precursor Protein Secretases; Animals; Azepines; Brain; Dendr | 2008 |
Control of acute, chronic, and constitutive hyperammonemia by wild-type and genetically engineered Lactobacillus plantarum in rodents.
Topics: Acute Disease; Alanine; Ammonia; Animals; Carbon Tetrachloride; Chronic Disease; Disease Models, Ani | 2008 |
Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.
Topics: Adenocarcinoma; Alanine; Animals; Biomarkers, Tumor; Carbon Isotopes; Disease Models, Animal; Lactic | 2008 |
Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.
Topics: Adenocarcinoma; Alanine; Animals; Biomarkers, Tumor; Carbon Isotopes; Disease Models, Animal; Lactic | 2008 |
Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.
Topics: Adenocarcinoma; Alanine; Animals; Biomarkers, Tumor; Carbon Isotopes; Disease Models, Animal; Lactic | 2008 |
Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.
Topics: Adenocarcinoma; Alanine; Animals; Biomarkers, Tumor; Carbon Isotopes; Disease Models, Animal; Lactic | 2008 |
Requirement of Notch activation during regeneration of the intestinal epithelia.
Topics: Alanine; Amyloid Precursor Protein Secretases; Animals; Azepines; Basic Helix-Loop-Helix Transcripti | 2009 |
Selective noradrenergic vulnerability in α-synuclein transgenic mice.
Topics: Alanine; alpha-Synuclein; Animals; Disease Models, Animal; Humans; Mice; Mice, Inbred C3H; Mice, Inb | 2010 |
Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo.
Topics: Age Factors; Alanine; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Arginine; Axons | 2009 |
Effect of a dominant-negative form of ADAM10 in a mouse model of Alzheimer's disease.
Topics: ADAM Proteins; ADAM10 Protein; Age Factors; Alanine; Alzheimer Disease; Amyloid beta-Protein Precurs | 2009 |
Excitotoxicity-induced endocytosis confers drug targeting in cerebral ischemia.
Topics: Alanine; Animals; Animals, Newborn; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Dextrans; Dise | 2009 |
Assessment of GS-9219 in a pet dog model of non-Hodgkin's lymphoma.
Topics: Alanine; Animals; Animals, Domestic; Anorexia; Antineoplastic Agents; Area Under Curve; Diarrhea; Di | 2009 |
The effects of group III mGluR ligands on pentylenetetrazol-induced kindling of seizures and hippocampal amino acids concentration.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Convulsants; Disease Models, Animal; Dose-Response Re | 2009 |
Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease.
Topics: Alanine; alpha-Synuclein; Animals; Aspartic Acid; Basal Ganglia; Cell Count; Dependovirus; Disease M | 2009 |
The proinflammatory action of microglial P2 receptors is enhanced in SOD1 models for amyotrophic lateral sclerosis.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Cell Line, Transformed; Ce | 2009 |
Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death.
Topics: Alanine; Animals; Apoptosis; Autophagy; Base Sequence; Disease Models, Animal; Heart Failure; HSP20 | 2009 |
BMAA neurotoxicity in Drosophila.
Topics: Alanine; Amino Acids, Diamino; Analysis of Variance; Animals; Behavior, Animal; Chromatography, High | 2009 |
Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amyloid; Animals; Aspartic Acid; Disease Mode | 2009 |
Mice expressing the A53T mutant form of human alpha-synuclein exhibit hyperactivity and reduced anxiety-like behavior.
Topics: Age Factors; Alanine; alpha-Synuclein; Analysis of Variance; Animals; Anxiety; Disease Models, Anima | 2010 |
T(2) relaxation times of (13)C metabolites in a rat hepatocellular carcinoma model measured in vivo using (13)C-MRS of hyperpolarized [1-(13)C]pyruvate.
Topics: Alanine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Disease Models, Animal; Liver Neoplasm | 2010 |
Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption.
Topics: Alanine; Alcohol Drinking; Analysis of Variance; Animals; Benzazepines; Central Nervous System Depre | 2010 |
Simultaneous two-dimensional HPLC determination of free D-serine and D-alanine in the brain and periphery of mutant rats lacking D-amino-acid oxidase.
Topics: Alanine; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; D-Amino-Acid Oxidase; Disea | 2011 |
Relationship between neuropathology and disease progression in the SOD1(G93A) ALS mouse.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Di | 2011 |
Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Cells, Cultured; Coculture Techniques; Disease Mode | 2011 |
Hind limb muscle atrophy precedes cerebral neuronal degeneration in G93A-SOD1 mouse model of amyotrophic lateral sclerosis: a longitudinal MRI study.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Brain; Disease Models, Animal; Glycine; Hindlimb; H | 2011 |
Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir.
Topics: Administration, Oral; Alanine; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegaloviru | 2011 |
13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression.
Topics: Alanine; Animals; Carbon Isotopes; Citric Acid Cycle; Disease Models, Animal; Gene Expression Profil | 2011 |
Dopamine-depletion and increased α-synuclein load induce degeneration of cortical cholinergic fibers in mice.
Topics: Acetylcholinesterase; Alanine; alpha-Synuclein; Analysis of Variance; Animals; bcl-2-Associated X Pr | 2011 |
Severe dysfunction of respiratory chain and cholesterol metabolism in Atp7b(-/-) mice as a model for Wilson disease.
Topics: Aconitate Hydratase; Adenosine Triphosphatases; Alanine; Animals; Brain; Carnitine; Cation Transport | 2011 |
N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development.
Topics: Acetylcysteine; Alanine; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Free Radic | 2012 |
PGC-1α protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Di | 2011 |
Pharmacological activity of a Bv8 analogue modified in position 24.
Topics: Alanine; Amino Acid Substitution; Amphibian Proteins; Analgesics; Animals; Chemotaxis; CHO Cells; Cr | 2012 |
Preliminary studies on the effect of rebamipide against the trypsin and egg-albumin induced experimental model of asthma.
Topics: Alanine; Animals; Asthma; Disease Models, Animal; Female; Histamine Release; Male; Mice; Ovalbumin; | 2011 |
Reduced expression of the μ opioid receptor in some, but not all, brain regions in mice with OPRM1 A112G.
Topics: Alanine; Amino Acid Substitution; Analgesics, Opioid; Animals; Disease Models, Animal; Down-Regulati | 2012 |
Effects of the selective kainate receptor antagonist ACET on altered sensorimotor gating in a genetic model of reduced NMDA receptor function.
Topics: Alanine; Animals; Antipsychotic Agents; Carrier Proteins; Disease Models, Animal; Gene Knockdown Tec | 2012 |
Toxic role of K+ channel oxidation in mammalian brain.
Topics: 2,2'-Dipyridyl; Age Factors; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein | 2012 |
A brain aggregate model gives new insights into the pathobiology and treatment of prion diseases.
Topics: Alanine; Animals; Azepines; Brain; Cathepsin D; Dendrites; Disease Models, Animal; Embryo, Mammalian | 2012 |
Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer's disease.
Topics: Age Factors; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases | 2012 |
Kv1.1 knock-in ataxic mice exhibit spontaneous myokymic activity exacerbated by fatigue, ischemia and low temperature.
Topics: Alanine; Animals; Ataxia; Calcium; Calcium Signaling; Cold Temperature; Disease Models, Animal; Elec | 2012 |
Group I mGluR antagonist rescues the deficit of D1-induced LTP in a mouse model of fragile X syndrome.
Topics: Alanine; Animals; Cells, Cultured; Disease Models, Animal; Fragile X Mental Retardation Protein; Fra | 2012 |
Effects of supplementation on food intake, body weight and hepatic metabolites in the citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mouse model of human citrin deficiency.
Topics: Alanine; Animals; Body Weight; Cholestasis, Intrahepatic; Citrullinemia; Dietary Proteins; Disease M | 2012 |
Terminal-restriction fragment length polymorphism (T-RFLP) analysis for changes in the gut microbiota profiles of indomethacin- and rebamipide-treated mice.
Topics: Alanine; Animals; Cecum; Disease Models, Animal; DNA, Bacterial; Drug Therapy, Combination; Female; | 2012 |
Correlation of plasma amino acid concentrations and chondroprotective effects of glucosamine and fish collagen peptide on the development of osteoarthritis.
Topics: Alanine; Animals; Cartilage, Articular; Collagen; Disease Models, Animal; Female; Glucosamine; Histo | 2013 |
Effects of glycine supplementation on myocardial damage and cardiac function after severe burn.
Topics: Adenosine Triphosphate; Alanine; Analysis of Variance; Animals; Aspartate Aminotransferases; Biomark | 2013 |
Staphylococcus aureus strains lacking D-alanine modifications of teichoic acids are highly susceptible to human neutrophil killing and are virulence attenuated in mice.
Topics: Alanine; alpha-Defensins; Animals; Anti-Bacterial Agents; Bacterial Proteins; Disease Models, Animal | 2002 |
Altered long-term corticostriatal synaptic plasticity in transgenic mice overexpressing human CU/ZN superoxide dismutase (GLY(93)-->ALA) mutation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Alanine; Animals; Avo | 2003 |
Nutritional benefits of enteral alanyl-glutamine supplementation on rat small intestinal damage induced by cyclophosphamide.
Topics: Alanine; Amino Acid Transport Systems; Animals; Antineoplastic Agents, Alkylating; Biomarkers; Body | 2003 |
Immunohistochemical study on the distribution of alpha-synuclein in the central nervous system of transgenic mice expressing a human Cu/Zn superoxide dismutase mutation.
Topics: Alanine; alpha-Synuclein; Animals; Central Nervous System; Disease Models, Animal; Glycine; Humans; | 2003 |
The AMPA receptor antagonist NBQX prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis.
Topics: Age Factors; Alanine; Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Behavior, Animal | 2003 |
Open space swimming test to index antidepressant activity.
Topics: Alanine; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Drug | 2003 |
Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation.
Topics: Alanine; Animals; Cord Blood Stem Cell Transplantation; Disease Models, Animal; Disease Progression; | 2003 |
Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice.
Topics: Action Potentials; Alanine; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Disease Models | 2004 |
The serotonin precursor 5-hydroxytryptophan delays neuromuscular disease in murine familial amyotrophic lateral sclerosis.
Topics: 5-Hydroxytryptophan; Aging; Alanine; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Body | 2003 |
alpha-Amino-3-hydroxy-5-methyl-isoxazole-4-propionate receptors in spinal cord motor neurons are altered in transgenic mice overexpressing human Cu,Zn superoxide dismutase (Gly93-->Ala) mutation.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Cell Culture Techniques; Disease Models, Animal; El | 2003 |
An altered self-peptide with superagonist activity blocks a CD8-mediated mouse model of type 1 diabetes.
Topics: Adoptive Transfer; Alanine; Amino Acid Substitution; Animals; Autoantigens; CD8-Positive T-Lymphocyt | 2004 |
An ALS mouse model with a permeable blood-brain barrier benefits from systemic cyclosporine A treatment.
Topics: Age Factors; Alanine; Amyotrophic Lateral Sclerosis; Animals; ATP Binding Cassette Transporter, Subf | 2004 |
Metabolism of 13C-enriched D-fructose in hepatocytes from Goto-Kakizaki rats.
Topics: Alanine; Animals; Buffers; Carbon Isotopes; Cells, Cultured; Diabetes Mellitus, Type 2; Disease Mode | 2004 |
Effects of high-intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Fe | 2004 |
Effects of high-intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Fe | 2004 |
Effects of high-intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Fe | 2004 |
Effects of high-intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Fe | 2004 |
Effects of high-intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Fe | 2004 |
Effects of high-intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Fe | 2004 |
Effects of high-intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Fe | 2004 |
Effects of high-intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Fe | 2004 |
Effects of high-intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Fe | 2004 |
rBPI(10-193) is secreted by CHO cells and retains the activity of rBPI21.
Topics: Alanine; Amino Acid Substitution; Animals; Antimicrobial Cationic Peptides; Bacteremia; Blood Protei | 2004 |
Creation of a mouse expressing defective human factor IX.
Topics: Alanine; Animals; Antibodies; Antigens; Blood Coagulation; Cell Line; Disease Models, Animal; DNA; F | 2004 |
Decreased activity and expression of intestinal oligopeptide transporter PEPT1 in rats with hyperthyroidism in vivo.
Topics: Alanine; Animals; Carbon Radioisotopes; Dipeptides; Disease Models, Animal; Dose-Response Relationsh | 2004 |
Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS.
Topics: Age Factors; Alanine; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Glycine; Human | 2004 |
Hepatic glycogen breakdown is implicated in the maintenance of plasma mannose concentration.
Topics: Administration, Oral; Alanine; Animals; Arabinose; Blood Glucose; Chlorogenic Acid; Diabetes Mellitu | 2005 |
Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease.
Topics: Alanine; alpha-Synuclein; Animals; Brain; Disease Models, Animal; Dopamine; Female; Gene Expression; | 2004 |
Exacerbated synucleinopathy in mice expressing A53T SNCA on a Snca null background.
Topics: Age Factors; Alanine; alpha-Synuclein; Animals; Behavior, Animal; Blotting, Western; Disease Models, | 2005 |
Protective effect of intra-rectal administration of rebamipide on dextran sulfate sodium-induced rat colitis.
Topics: Administration, Rectal; Alanine; Animals; Anti-Ulcer Agents; Anticoagulants; Colitis; Dextran Sulfat | 2004 |
Delineation of the minimal encephalitogenic epitope of proteolipid protein peptide(91-110) and critical residues required for induction of EAE in HLA-DR3 transgenic mice.
Topics: Alanine; Animals; Apoproteins; Brain; Cell Proliferation; Cytokines; Disease Models, Animal; Dose-Re | 2005 |
Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein.
Topics: Age Factors; Alanine; alpha-Synuclein; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Blo | 2005 |
Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease.
Topics: Alanine; alpha-Synuclein; Animals; Brain; Disease Models, Animal; Energy Metabolism; Mice; Mice, Inb | 2005 |
MRL/lpr mice have alterations in brain metabolism as shown with [1H-13C] NMR spectroscopy.
Topics: Alanine; Amino Acids; Animals; Brain; Brain Diseases, Metabolic; Brain Edema; Carbon Radioisotopes; | 2005 |
Topiramate prevents excitotoxic damage in the newborn rodent brain.
Topics: Alanine; Animals; Animals, Newborn; Brain; Cerebral Palsy; Disease Models, Animal; Dose-Response Rel | 2005 |
COX-1 and COX-2 conversely promote and suppress ischemia-reperfusion gastric injury in mice.
Topics: Alanine; Animals; Blotting, Western; Celiac Artery; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygena | 2005 |
Direct autoradiographic evidence that rebamipide interacts with neutrophils in dextran sulfate sodium induced colitis in rats.
Topics: Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Colitis; Dextran Sulfate; Disease Models, | 2005 |
Rebamipide enema is effective for treatment of experimental dextran sulfate sodium induced colitis in rats.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Colitis, Ulcerative; D | 2005 |
The CD8+ T-cell response to an Epstein-Barr virus-related gammaherpesvirus infecting rhesus macaques provides evidence for immune evasion by the EBNA-1 homologue.
Topics: Alanine; Animals; CD8-Positive T-Lymphocytes; Disease Models, Animal; Epitopes, T-Lymphocyte; Epstei | 2005 |
Alcohol potently modulates climbing fiber-->Purkinje neuron synapses: role of metabotropic glutamate receptors.
Topics: Alanine; Animals; Aspartic Acid; Disease Models, Animal; Ethanol; Long-Term Synaptic Depression; Mal | 2006 |
Animal model of oculopharyngeal muscular dystrophy.
Topics: Actins; Alanine; Animals; Disease Models, Animal; Inclusion Bodies; Mice; Mice, Transgenic; Muscle, | 2005 |
Differential changes of group II and group III mGluR function in central amygdala neurons in a model of arthritic pain.
Topics: Alanine; Aminobutyrates; Amygdala; Animals; Arthritis; Bridged Bicyclo Compounds; Disease Models, An | 2006 |
A truncated Bacillus subtilis dal gene with a 3' ssrA gene tag regulates the growth and virulence of racemase-deficient Listeria monocytogenes.
Topics: Alanine; Alanine Racemase; Animals; Bacillus subtilis; CD8-Positive T-Lymphocytes; Cell Line; Cytopl | 2006 |
Effect of rebamipide on the colonic barrier in interleukin-10-deficient mice.
Topics: Alanine; Animals; Anti-Ulcer Agents; Colon; Disease Models, Animal; Female; Flow Cytometry; Helicoba | 2007 |
Neutral Na-amino acid cotransport is differentially regulated by glucocorticoids in the normal and chronically inflamed rabbit small intestine.
Topics: Alanine; Amino Acid Transport System ASC; Animals; Cell Membrane; Disease Models, Animal; Enteritis; | 2007 |
S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila.
Topics: Alanine; Animals; Animals, Genetically Modified; Disease Models, Animal; Drosophila; Drosophila Prot | 2007 |
The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo.
Topics: Alanine; Animals; Aspartic Acid; Brain Ischemia; Cerebral Arteries; Disease Models, Animal; Gene Exp | 2007 |
BACE1 and mutated presenilin-1 differently modulate Abeta40 and Abeta42 levels and cerebral amyloidosis in APPDutch transgenic mice.
Topics: Alanine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases | 2007 |
[Soluble CD40 ligand: a potential marker of cardiovascular risk].
Topics: Abciximab; Acute Coronary Syndrome; Alanine; Angina, Unstable; Animals; Antibodies, Monoclonal; Anti | 2007 |
Interaction between murine spf-ash mutation and genetic background yields different metabolic phenotypes.
Topics: Alanine; Ammonia; Animals; Arginine; Citrulline; Disease Models, Animal; Female; Glycine; Injections | 2007 |
1H NMR-based metabolomic analysis of liver, serum, and brain following ethanol administration in rats.
Topics: Alanine; Alcoholic Intoxication; Animals; Antioxidants; Brain; Butylated Hydroxytoluene; Central Ner | 2008 |
Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets.
Topics: Alanine; Analysis of Variance; Animals; Animals, Newborn; Arginine; Atrophy; Chlorides; Cryptosporid | 2008 |
Effective treatment with oral administration of rebamipide in a mouse model of Sjögren's syndrome.
Topics: Administration, Oral; Alanine; Animals; Anti-Inflammatory Agents; Autoantibodies; Cell Division; Cyt | 2008 |
Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Glycine; Humans; Mice; Mice | 2008 |
Tissue inhibitor of metalloproteinases-3 (TIMP-3) expression is increased during serum deprivation-induced neuronal apoptosis in vitro and in the G93A mouse model of amyotrophic lateral sclerosis: a potential modulator of Fas-mediated apoptosis.
Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Cell Line, Tumo | 2008 |
Characterisation of electrogenic nutrient absorption in the Cftr TgH(neoim)Hgu mouse model.
Topics: Alanine; Animals; Biological Transport; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance R | 2008 |
Vulnerability of gastric mucosa to prednisolone in rats chronically exposed to cigarette smoke.
Topics: Alanine; Animals; Anti-Ulcer Agents; Blood Gas Analysis; Dinoprostone; Disease Models, Animal; Gastr | 2008 |
Long-term prevention of Alzheimer's disease-like behavioral deficits in PDAPP mice carrying a mutation in Asp664.
Topics: Age Factors; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Anal | 2008 |
Metabolism and transport of L-glutamine and L-alanine by renal tubules of chickens.
Topics: Acidosis, Respiratory; Alanine; Alkalosis, Respiratory; Animals; Biological Transport; Carbon Dioxid | 1983 |
Morphological and functional changes in the gut after massive small bowel resection and colon interposition in rhesus monkeys.
Topics: Adaptation, Physiological; Alanine; Animals; Colon; Disease Models, Animal; Glucose; Hyperplasia; Hy | 1984 |
Jejunal transport properties of piebald mouse model for Hirschsprung's disease.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Disease Models, Animal; Female; Jejunum | 1980 |
Changes in alanine turnover rate due to nutritional and genetic obesity in the rat.
Topics: Alanine; Analysis of Variance; Animals; Body Weight; Diet; Disease Models, Animal; Energy Intake; Ma | 1994 |
Effects of rotavirus on epithelial transport in rabbit small intestine.
Topics: Alanine; Animals; Biological Transport; Cells, Cultured; Diarrhea; Dinoprostone; Disease Models, Ani | 1994 |
Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril.
Topics: Alanine; Amino Acid Sequence; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Atri | 1994 |
Subchronic toxicity of 3-phenylamino alanine, an impurity in L-tryptophan reported to be associated with eosinophilia-myalgia syndrome.
Topics: Administration, Oral; Alanine; Animals; Blood Chemical Analysis; Brain; Chromatography, High Pressur | 1995 |
Glucose metabolism distal to a critical coronary stenosis in a canine model of low-flow myocardial ischemia.
Topics: Alanine; Animals; Coronary Disease; Coronary Vessels; Disease Models, Animal; Dogs; Endocardium; Fat | 1996 |
Inhibition of both angiotensin-converting enzyme and neutral endopeptidase by S21402 (RB105) in rats with experimental myocardial infarction.
Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; | 1996 |
The biochemical basis of increased hepatic glucose production in a mouse model of type 2 (non-insulin-dependent) diabetes mellitus.
Topics: Alanine; Animals; Body Mass Index; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dietary Fats; Disea | 1995 |
Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs.
Topics: Alanine; Animals; Aspartic Acid; Atrophy; Diet; Disease Models, Animal; Duodenum; Epithelium; Female | 1996 |
Impairment of antioxidants in colonic epithelial cells isolated from trinitrobenzene sulphonic acid-induced colitis rats. Protective effect of rebamipide.
Topics: Alanine; Analysis of Variance; Animals; Anti-Ulcer Agents; Antioxidants; Colitis; Culture Techniques | 1996 |
Effects of rebamipide on bile acid-induced inhibition of gastric epithelial repair in a rabbit cell culture model.
Topics: Actins; Alanine; Animals; Anti-Ulcer Agents; Bromodeoxyuridine; Cell Division; Cell Movement; Cells, | 1996 |
Treatment with growth hormone and insulin-like growth factor-1 in septicemia: effects on carbohydrate metabolism.
Topics: Alanine; Animals; Bacteremia; Blood Glucose; Calorimetry, Indirect; Carbohydrate Metabolism; Disease | 1998 |
Changes in brain organic osmolytes in experimental cerebral ischemia.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Brain Ischemia; Creatine; Disease Mod | 1998 |
Studies of arginine metabolism and salt sensitivity in the Dahl/Rapp rat models of hypertension.
Topics: Alanine; Animals; Arginine; Argininosuccinate Synthase; Blood Pressure; Body Weight; Citrulline; Dis | 1998 |
Rebamipide treatment activates epidermal growth factor and its receptor expression in normal and ulcerated gastric mucosa in rats: one mechanism for its ulcer healing action?
Topics: Alanine; Animals; Anti-Ulcer Agents; Disease Models, Animal; Epidermal Growth Factor; ErbB Receptors | 1998 |
Effect of rebamipide on liver damage and increased tumor necrosis factor in a rat model of endotoxin shock.
Topics: Alanine; Animals; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli; Lipopolysaccharides; | 1998 |
Inhibitory effects of rebamipide on ENNG-induced duodenal carcinogenesis in mice: a possible strategy for chemoprevention of gastrointestinal cancers.
Topics: Alanine; Animals; Antineoplastic Agents; Carcinogens; Disease Models, Animal; Dose-Response Relation | 1998 |
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Creatine; Disease Models, Animal; Glycine; Humans; | 1999 |
Anticonvulsant activity of PNU-151774E in the amygdala kindled model of complex partial seizures.
Topics: Acetates; Alanine; Amines; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Benzylamines; Carba | 1999 |
Antiplatelet and antithrombotic effects of orbofiban, a new orally active GPIIb/IIIa antagonist, in guinea pigs.
Topics: Adenosine Diphosphate; Administration, Oral; Alanine; Animals; Arteriovenous Shunt, Surgical; Aspiri | 2000 |
Neuroprotective effects of kynurenine-3-hydroxylase inhibitors in models of brain ischemia.
Topics: Alanine; Animals; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Enzyme Inhibitors; Ge | 1999 |
Activation and response to axotomy of microglia in the facial motor nuclei of G93A superoxide dismutase transgenic mice.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Axotomy; Disease Models, Animal; Facial Nerve; Glyc | 2000 |
Positive effect of rebamipide on gastric permeability in mice after eradication of Helicobacter felis.
Topics: Alanine; Animals; Anti-Ulcer Agents; Disease Models, Animal; Gastric Mucosa; Helicobacter; Helicobac | 2000 |
Rebamipide, an antiulcer drug, prevents DSS-induced colitis formation in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Interl | 2000 |
Sequence of normal canine COL1A1 cDNA and identification of a heterozygous alpha1(I) collagen Gly208Ala mutation in a severe case of canine osteogenesis imperfecta.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Collagen; Collagen Type I; Collagen Type I, al | 2000 |
In vitro 1H and 31P NMR spectroscopic evidence of multiple aberrant biochemical pathways in murine trisomy 16 brain development.
Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Choline; Creatine; Disease Models, Ani | 2000 |
Boronated dipeptide borotrimethylglycylphenylalanine as a potential boron carrier in boron neutron capture therapy for malignant brain tumors.
Topics: Alanine; Animals; Autoradiography; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neop | 2001 |
Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents.
Topics: Afferent Pathways; Alanine; Animals; Animals, Newborn; Capsaicin; Colitis; Denervation; Disease Mode | 2001 |
Striatal AMPA receptor binding is unaltered in the MPTP-lesioned macaque model of Parkinson's disease and dyskinesia.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alanine; Animals; Apomorphine; Autoradiography; Bindin | 2002 |
Glutamine concentration and tissue exchange with intravenously administered alpha-ketoglutaric acid and ammonium: a dose-response study in the pig.
Topics: Acidosis; Alanine; Amino Acids; Animals; Blood Gas Analysis; Disease Models, Animal; Dose-Response R | 2002 |
Effect of amino-oxyacetic acid (AOAA) on focal penicillin seizures.
Topics: Acetates; Alanine; Aminooxyacetic Acid; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Ani | 1978 |
Fine structure of the Legionnaires' disease bacterium. In-vitro and in-vivo studies of four isolates.
Topics: Alanine; Animals; Bacteria; Cell Membrane; Cell Wall; Diaminopimelic Acid; Disease Models, Animal; G | 1979 |
The mechanism of hypoglycemia due to semistarvation in the rat.
Topics: Alanine; Animals; Blood Glucose; Disease Models, Animal; Energy Metabolism; Glucagon; Glucose; Glyce | 1976 |
Fasting-induced hypoglycemia in experimentally malnourished rats.
Topics: Adaptation, Physiological; Alanine; Aminobutyrates; Animals; Brain Chemistry; Disease Models, Animal | 1977 |
Contents of several amino acids in the cerebellum, brain stem and cerebrum of the 'staggerer', 'weaver' and 'nervous' neurologically mutant mice.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Diseases; Brain Stem; Cerebellum; Disease | 1976 |
Therapeutic effects of oral rebamipide and in combination with cimetidine on experimental gastritis in rats.
Topics: Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Cimetidine; Disease Models, Animal; Drug | 1992 |
Chronic hypoxia in neuronal cell culture: metabolic consequences.
Topics: Alanine; Animals; Bicarbonates; Binding, Competitive; Brain Chemistry; Cell Hypoxia; Cells, Cultured | 1990 |
Alanine stimulation of water and sodium absorption in a model of secretory diarrhea.
Topics: Absorption; Alanine; Animals; Diarrhea; Disease Models, Animal; Fluid Therapy; Intestinal Absorption | 1990 |
Lathyrism: evidence for role of the neuroexcitatory aminoacid BOAA.
Topics: Adolescent; Adult; Alanine; Amino Acids, Diamino; Animals; beta-Alanine; Central Nervous System; Chi | 1986 |
Alterations of fasting glucose and fat metabolism in intrauterine growth-retarded newborn dogs.
Topics: Aging; Alanine; Animals; Animals, Newborn; Blood Glucose; Disease Models, Animal; Dogs; Energy Metab | 1989 |
Relationship between elastolytic acitivity and experimental emphysema-induced properties of papain preparations.
Topics: Alanine; Animals; Arginine; Benzoates; Butanols; Cricetinae; Disease Models, Animal; Elastic Tissue; | 1974 |
Concentration of amino acids in the brain of cobalt-epileptic rat.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Cobalt; Disease Mode | 1973 |
Absolute levels of some free amino acids in normal and biologically fractionated retinas.
Topics: Adaptation, Ocular; Alanine; Amino Acids; Aminobutyrates; Animals; Autoanalysis; Dark Adaptation; Di | 1973 |
Some kinetic properties of the allosteric M-type pyruvate kinase from rat liver; influence of pH and the nature of amino acid inhibition.
Topics: Adenosine Triphosphate; Alanine; Allosteric Regulation; Animals; Binding Sites; Disease Models, Anim | 1973 |
Plasma amino acids in experimental acute hepatic failure and their relationship to brain tryptophan.
Topics: Acute Disease; Alanine; Amino Acids; Animals; Brain Chemistry; Disease Models, Animal; Glycine; Hepa | 1974 |
[Behavior of serum amino acids in rats with experimentally produced hyperphenylalaninemia].
Topics: Alanine; Amino Acids; Animals; Disease Models, Animal; Glutamates; Phenylalanine; Proline; Rats; Thr | 1971 |