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alanine and Delayed Hypersensitivity

alanine has been researched along with Delayed Hypersensitivity in 27 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"Two strains of guinea-pigs selectively bred for either high (IMM/S) or low (IMM/R) responsiveness to ovalbumin-induced respiratory anaphylaxis were examined for their immune response to a copolymer of L-glutamic acid and L-alanine (GA), a copolymer of L-glutamic acid and L-tyrosine (GT), and to a dinitro-phenyl derivative of a homopolymer of L-lysine (DNP-PLL)."3.66Characterization of two strains of selectively bred guinea-pigs. 2. Differences in immune response to synthetic polypeptides. ( Bertelsen, C; Koch, C; Lundberg, L; Magnusson, M, 1983)
" Three random linear copolymers composed of two or three of the amino acids d-tyrosine, d-glutamic acid, d-alanine and d-lysine, and a branched multichain copolymer with a poly-d-lysine backbone and polymeric side chains of d-tyrosine and d-glutamic acid, were found to be non-antigenic in rabbits, by precipitin and passive cutaneous anaphylaxis, and in guinea pigs, by delayed hypersensitivity tests."3.64Relation between optical configuration and immunogenicity of synthetic polypeptides. ( Borek, F; Fuchs, S; Sela, M; Stupp, Y, 1965)
"L-alanosine is an antitumor compound which has recently entered clinical trials."1.27Effect of L-alanosine on immune response. ( Bassi, L; Mistrello, G, 1984)
"All of the guinea pigs developing delayed hypersensitivity also had significant antibody levels in their sera."1.25Specific immune response genes of the guinea pig. I. Dominant genetic control of immune responsiveness to copolymers of L-glutamic acid and L-alanine and L-glutamic acid and L-tyrosine. ( Benacerraf, B; Bluestein, HG; Green, I, 1971)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199025 (92.59)18.7374
1990's1 (3.70)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Galleani, C1
Bautista-Villanueva, S1
Piorno, I1
Moya, B1
Mielgo, R1
Gil, M1
Crespo, JF1
Leskowitz, S2
Lundberg, L1
Koch, C1
Magnusson, M1
Bertelsen, C1
Mistrello, G1
Bassi, L1
Kipps, TJ1
Weinberger, JZ1
Benacerraf, B4
Dorf, ME1
Wieczorek, Z1
Zimecki, M1
Pedyczak, A1
Lisowski, M1
Siemion, IZ1
Miller, JF1
Vadas, MA1
Whitelaw, A1
Gamble, J1
Bernard, C1
Kotani, S1
Watanabe, Y1
Kinoshita, F1
Morisaki, I1
Kato, K1
Zeiger, AR1
Maurer, PH4
Kennedy, MK1
Jenkins, MK1
Miller, SD1
Schneider, CH2
de Weck, AL2
Schenkel, E1
Wirz, W1
Lazary, S1
Adam, A1
Ciorbaru, R1
Ellouz, F1
Petit, JF1
Lederer, E1
Brown, PC1
Glynn, LE1
Callahan, HJ1
Yaron, A1
Dunham, EK1
Schlossman, SF1
Wood, FD1
Pearson, CM1
Tanaka, A1
Bluestein, HG3
Green, I3
Dvorak, HF1
Simpson, BA1
Bast, RC1
Teitelbaum, D1
Meshorer, A1
Hirshfeld, T1
Arnon, R1
Sela, M3
Ohno, R1
Hersh, EM1
Ben-Efraim, S1
Liacopoulos, P1
Borek, F2
Stupp, Y2
Fuchs, S1

Other Studies

27 other studies available for alanine and Delayed Hypersensitivity

ArticleYear
Remdesivir-Induced Nonimmediate Cutaneous Hypersensitivity Reaction.
    Journal of investigational allergology & clinical immunology, 2023, Jun-15, Volume: 33, Issue:3

    Topics: Alanine; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Skin

2023
Mechanism of delayed reactions.
    Science (New York, N.Y.), 1967, Jan-20, Volume: 155, Issue:3760

    Topics: Alanine; Animals; Antigen-Antibody Reactions; Arsenicals; Glutamates; Guinea Pigs; Hypersensitivity,

1967
Characterization of two strains of selectively bred guinea-pigs. 2. Differences in immune response to synthetic polypeptides.
    Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology, 1983, Volume: 91, Issue:3

    Topics: Alanine; Anaphylaxis; Animals; Female; Genes, MHC Class II; Guinea Pigs; Hypersensitivity, Delayed;

1983
Effect of L-alanosine on immune response.
    Journal of immunopharmacology, 1984, Volume: 6, Issue:1-2

    Topics: Alanine; Animals; Antibiotics, Antineoplastic; Antibody Formation; Cells, Cultured; Cytotoxicity Tes

1984
Comparison of T and B cell reactivity to antigens under Ir gene control.
    Journal of immunology (Baltimore, Md. : 1950), 1980, Volume: 124, Issue:3

    Topics: Alanine; Animals; Antibody Specificity; Antigens; B-Lymphocytes; Cross Reactions; Dose-Response Rela

1980
Immunosuppressive activity of alanine analogs of cyclolinopeptide A.
    Archivum immunologiae et therapiae experimentalis, 1993, Volume: 41, Issue:5-6

    Topics: Alanine; Amino Acid Sequence; Animals; Circular Dichroism; Hemolytic Plaque Technique; Hypersensitiv

1993
Histocompatibility linked immune responsiveness and restrictions imposed on sensitized lymphocytes.
    The Journal of experimental medicine, 1977, Jun-01, Volume: 145, Issue:6

    Topics: Alanine; Animals; Antibody Formation; Antigens; Female; Genes; Glutamates; Histocompatibility; Hyper

1977
The effect of replacement of L-alanine residue by glycine, L-serine or D-alanine in an N-acetylmuramyl-L-alanyl-D-isoglutamine on immunoadjuvancies of molecules.
    Biken journal, 1977, Volume: 20, Issue:2

    Topics: Adjuvants, Immunologic; Alanine; Animals; Antibody Formation; Chemical Phenomena; Chemistry; Cornea;

1977
Genetic control of the immune response in guinea pigs to the known sequence polymer (Tyr-Ala-Glu-Gly)n1,2.
    Journal of immunology (Baltimore, Md. : 1950), 1976, Volume: 117, Issue:2

    Topics: Alanine; Amino Acid Sequence; Animals; Antibody Formation; Glutamates; Glycine; Guinea Pigs; Hyperse

1976
Immune responses of inbred guinea pigs against random terpolymers containing L glutamic acid and L alanine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 150, Issue:2

    Topics: Alanine; Animals; Antibody Formation; Antigens; Binding Sites, Antibody; Female; Glutamates; Guinea

1975
Mechanisms of genetic control of immune responses. II. Nonresponsiveness in BALB/c GT-specific cell-mediated immune responses does not correlate with the absence of functional T cells or the induction of suppressor T cells.
    Immunogenetics, 1986, Volume: 23, Issue:5

    Topics: Alanine; Animals; Cyclophosphamide; Cytotoxicity, Immunologic; Epitopes; Genes, MHC Class II; H-2 An

1986
Immunogenicity of fully defined lysine LAG dodecapeptides in guinea-pigs: with a note on an antigenic cooperation effect in the delayed immune response.
    Immunology, 1972, Volume: 23, Issue:6

    Topics: Alanine; Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; Cell Migration Inhibitio

1972
Peptide antigens for the study of interactions between determinants, antibodies and immunologically active cells.
    International archives of allergy and applied immunology, 1973, Volume: 45, Issue:1

    Topics: Alanine; Animals; Antibodies; Antibody Formation; Antibody-Producing Cells; Antigens; Cell Migration

1973
Adjuvant activity of monomeric bacterial cell wall peptidoglycans.
    Biochemical and biophysical research communications, 1974, Feb-04, Volume: 56, Issue:3

    Topics: Adjuvants, Immunologic; Alanine; Amino Acids; Carbohydrates; Cell Wall; Chromatography, Gel; Chromat

1974
The antigenicity of sequential polypetides. II. The antigenicity of some sequential polymers including several related to collagen.
    Immunology, 1973, Volume: 25, Issue:2

    Topics: Alanine; Amino Acid Sequence; Animals; Antibody Formation; Antigens; Collagen; Cross Reactions; Glyc

1973
Communication to the editors: The immunogenicity of a low molecular weight synthetic polypeptide.
    Immunochemistry, 1973, Volume: 10, Issue:3

    Topics: Alanine; Animals; Antibody Formation; Chromatography, Gel; Chromatography, Ion Exchange; Electrophor

1973
Synthesis and immunological properties of the oligolysyl-N-epsilon-dinitrophenyllysine and oligolysylalanylalanylalanyl-N-epsilon-dinitrophenyllysine peptide series.
    Biochemistry, 1974, Jan-15, Volume: 13, Issue:2

    Topics: Alanine; Amino Acid Sequence; Animals; Antibody Formation; Antigens; Carbon Radioisotopes; Chromatog

1974
Capacity of mycobacterial wax D and its subfractions to induce adjuvant arthritis in rats.
    International archives of allergy and applied immunology, 1969, Volume: 35, Issue:5

    Topics: Adjuvants, Immunologic; Alanine; Animals; Antigens; Arthritis; Chromatography; Glutamates; Hypersens

1969
Specific immune response genes of the guinea pig. V. Influence of the GA and GT immune response genes on the specificity of cellular and humoral immune responses to a terpolymer of L-glutamic acid, L-alanine, and L-tyrosine.
    The Journal of experimental medicine, 1972, Volume: 135, Issue:1

    Topics: Alanine; Animals; Antibody Formation; Antibody Specificity; Cells, Cultured; Cross Reactions; Genes;

1972
Cutaneous basophil hypersensitivity. 3. Participation of the basophil in hypersensitivity to antigen-antibody complexes, delayed hypersensitivity and contact allergy. Passive transfer.
    Journal of immunology (Baltimore, Md. : 1950), 1971, Volume: 107, Issue:1

    Topics: Alanine; Allergens; Animals; Antigen-Antibody Complex; Antigens; Arsenicals; Basophils; Benzene Deri

1971
Suppression of experimental allergic encephalomyelitis by a synthetic polypeptide.
    European journal of immunology, 1971, Volume: 1, Issue:4

    Topics: Alanine; Animals; Autoanalysis; Brain; Cytochromes; Encephalomyelitis, Autoimmune, Experimental; Glu

1971
Immunosuppressive effects of L-asparaginase.
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Alanine; Antibody Formation; Antigens; Asparaginase; Asparagin

1970
Specific immune response genes of the guinea pig. II. Relationship between the poly-L-lysine gene and the genes controlling immune responsiveness to copolymers of L-glutamic acid and L-alanine and L-glutamic acid and L-tyrosine in random-bred Hartley guin
    The Journal of experimental medicine, 1971, Aug-01, Volume: 134, Issue:2

    Topics: Alanine; Animals; Antibody Formation; Antigens; Breeding; Chromosomes; Female; Genes, Dominant; Glut

1971
Specific immune response genes of the guinea pig. I. Dominant genetic control of immune responsiveness to copolymers of L-glutamic acid and L-alanine and L-glutamic acid and L-tyrosine.
    The Journal of experimental medicine, 1971, Aug-01, Volume: 134, Issue:2

    Topics: Alanine; Animals; Antibody Formation; Antigens; Female; Genes, Dominant; Glutamates; Guinea Pigs; Hy

1971
The competitive effect of DNP-poly-L-lysine in responder and non-responder guinea pigs.
    Immunology, 1969, Volume: 16, Issue:5

    Topics: Alanine; Animals; Antibody Formation; Antigens; Dinitrophenols; Glutamine; Guinea Pigs; Haptens; Hyp

1969
Relation between optical configuration and immunogenicity of synthetic polypeptides.
    The Biochemical journal, 1965, Volume: 96, Issue:3

    Topics: Alanine; Animals; Antigens; Azo Compounds; Chemical Phenomena; Chemistry; Glutamates; Guinea Pigs; H

1965
Studies on the types of immune responses to synthetic antigens in guinea-pigs.
    Immunology, 1966, Volume: 11, Issue:6

    Topics: Alanine; Animals; Antibody Formation; Antigens; Glutamates; Guinea Pigs; Hypersensitivity, Delayed;

1966