Page last updated: 2024-11-08

alanine and Deficiency, Protein

alanine has been researched along with Deficiency, Protein in 20 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"The combined effect of moderate protein deficiency and infection lowered the enhanced uptake observed in moderately malnourished animals to a significant level (p less than 0."1.27Intestinal uptake of nutrients in normal and malnourished animals infected with Giardia lamblia. ( Ganguly, NK; Mahajan, RC; Upadhyay, P; Walia, BN, 1985)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199018 (90.00)18.7374
1990's2 (10.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Squibb, RL1
RAJALAKSHMI, R1
GOVINDARAJAN, KR1
RAMAKRISHNAN, CV1
Adibi, SA4
Tawa, NE1
Goldberg, AL1
Pérez-Sala, D1
Calleja, TR1
Parrilla, R1
Ayuso, MS1
Upadhyay, P1
Ganguly, NK1
Mahajan, RC1
Walia, BN1
Cheung, GP1
Cotropia, JP1
Sallach, HJ1
Sheerin, HE1
Bird, FH1
Paolucci, AM1
Spadoni, MA1
Pennetti, V1
Modesto, TA1
Morse, EL1
Amin, PM1
Silk, DB1
Kumar, PJ1
Perrett, D1
Clark, ML1
Dawson, AM1
Kelman, L1
Saunders, SJ1
Frith, L1
Wicht, S1
Corrigal, A1
Weller, LA1
Calloway, DH1
Margen, S1
Lindblad, BS2
Rahimtoola, RJ1
Khan, N1
Grimble, RF1
Whitehead, RG1
Drash, AL1
Pogglitsch, H1
Stübchen-Kirchner, H1
Stöckl, G1
Feldner, H1
McFarlane, IG1
Von Holt, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Acute Glycine Pharmacodynamic Study[NCT01610011]21 participants (Actual)Interventional2010-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Brain Glycine Increments After Oral Glycine Administration Measured With MRS as Glycine/Total Creatine, Normalized to the Glycine Dose Administered (g/kg).

Brain and plasma glycine levels are measured with proton magnetic resonance spectroscopy at 4T and analytically, respectively. Because glycine doses were limited to 30 g to avoid nausea and vomiting, some subjects with higher weights were administered lower doses per body weight of glycine (g/kg). Therefore, we corrected MRS data by the actual glycine dose administered (g/kg) to account for dosing differences. (NCT01610011)
Timeframe: For up to 2 hours

InterventionPercent brain glycine/creatine increase (Mean)
Glycine Administration Controls393
Glycine Administration GLDC Mutation Subjects677

Reviews

1 review available for alanine and Deficiency, Protein

ArticleYear
Metabolism of branched-chain amino acids in altered nutrition.
    Metabolism: clinical and experimental, 1976, Volume: 25, Issue:11

    Topics: Alanine; Amino Acids, Essential; Animals; Biological Transport; Dietary Carbohydrates; Dietary Fats;

1976

Other Studies

19 other studies available for alanine and Deficiency, Protein

ArticleYear
NUTRITION AND BIOCHEMISTRY OF SURVIVAL DURING NEWCASTLE DISEASE VIRUS INFECTION. III. RELATION OF DIETARY PROTEIN TO NUCLEIC AND FREE AMINO ACIDS OF AVIAN LIVER.
    The Journal of nutrition, 1964, Volume: 82, Issue:4

    Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Birds; Chromatography; Dietary Proteins; DNA

1964
EFFECT OF DIETARY PROTEIN CONTENT ON VISUAL DISCRIMINATION LEARNING AND BRAIN BIOCHEMISTRY IN THE ALBINO RAT.
    Journal of neurochemistry, 1965, Volume: 12

    Topics: Acyltransferases; Alanine; Alanine Transaminase; Amino Acid Oxidoreductases; Aminobutyrates; Asparta

1965
Suppression of muscle protein turnover and amino acid degradation by dietary protein deficiency.
    The American journal of physiology, 1992, Volume: 263, Issue:2 Pt 1

    Topics: Alanine; Amino Acids; Animals; Dietary Proteins; Glutamine; Growth; Male; Muscle Proteins; Muscles;

1992
Effect of alanine supply on hepatic protein synthesis in animals maintained on a protein free diet.
    Molecular and cellular biochemistry, 1991, Dec-11, Volume: 108, Issue:2

    Topics: Alanine; Amino Acids; Animals; Dietary Proteins; Eukaryotic Initiation Factor-2; Kinetics; Liver; Ma

1991
Intestinal uptake of nutrients in normal and malnourished animals infected with Giardia lamblia.
    Digestion, 1985, Volume: 32, Issue:4

    Topics: Alanine; Animals; Dietary Proteins; Giardia; Giardiasis; Glucose; Intestinal Absorption; Mice; Prote

1985
The effects of dietary protein on the hepatic enzymes of serine metabolism in the rabbit.
    Archives of biochemistry and biophysics, 1969, Volume: 129, Issue:2

    Topics: Alanine; Animals; Caseins; Depression, Chemical; Diet; Dietary Proteins; Glycerol; Glycerolphosphate

1969
Studies on the competitive absorption of neutral L-amino acids from the avian small intestine.
    The Journal of nutrition, 1972, Volume: 102, Issue:12

    Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animal Nutritional Physiological Phenomena; Animals; Bi

1972
Modifications of serum-free amino acid patterns of Babinga adult pygmies after short-term feeding of a balanced diet.
    The American journal of clinical nutrition, 1973, Volume: 26, Issue:4

    Topics: Adolescent; Adult; Alanine; Amino Acids; Anti-Infective Agents; Black People; Central African Republ

1973
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
    The American journal of physiology, 1973, Volume: 225, Issue:2

    Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycin

1973
Amino acid and peptide absorption in patients with coeliac disease and dermatitis herpetiformis.
    Gut, 1974, Volume: 15, Issue:1

    Topics: Adult; Aged; Alanine; Amino Acids; Celiac Disease; Dermatitis Herpetiformis; Dipeptides; Glycine; Hu

1974
Effects of dietary protein restriction on albumin synthesis, albumin catabolism, and the plasma aminogram.
    The American journal of clinical nutrition, 1972, Volume: 25, Issue:11

    Topics: Adult; Alanine; Albumins; Amino Acids; Autoanalysis; Blood Volume; Carbon Isotopes; Dietary Proteins

1972
Nitrogen balance of men fed amino acid mixtures based on Rose's requirements, egg white protein, and serum free amino acid patterns.
    The Journal of nutrition, 1971, Volume: 101, Issue:11

    Topics: Adult; Alanine; Amino Acids; Dietary Proteins; Dietetics; Feces; Glutamates; Glycine; Histidine; Hum

1971
The venous plasma free amino acid levels during the first hours of life. I. After normal and short gestation and gestation complicated by hypertension, with special reference to the "small for dates" syndrome.
    Acta paediatrica Scandinavica, 1970, Volume: 59, Issue:1

    Topics: Alanine; Amino Acids; Arginine; Birth Weight; Blood Glucose; Body Height; Chromatography, Ion Exchan

1970
The venous plasma free amino acid levels during the first hours of life. II. In a lower socio-economic group of a refugee area in Karachi, West Pakistan, with special reference to the "small for dates" syndrome.
    Acta paediatrica Scandinavica, 1970, Volume: 59, Issue:1

    Topics: Alanine; Amino Acids; Birth Weight; Gestational Age; Glycine; Growth; Growth Disorders; Humans; Infa

1970
Changes in the concentration of specific amino acids in the serum of experimentally malnourished pigs.
    The British journal of nutrition, 1970, Volume: 24, Issue:2

    Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Dietary Proteins; Female; Gluconeogenesis; G

1970
Hormone and amino acid levels in altered nutritional states.
    The Journal of laboratory and clinical medicine, 1970, Volume: 76, Issue:5

    Topics: Adult; Alanine; Amino Acids; Aminobutyrates; Female; Growth Hormone; Humans; Insulin; Isoleucine; Le

1970
Alteration in the urinary excretion rate of amino acids and nitrogen by dietary means in obese and normal human subjects.
    The Journal of laboratory and clinical medicine, 1971, Volume: 77, Issue:2

    Topics: Adult; Alanine; Amino Acids; Creatinine; Female; Humans; Isoleucine; Leucine; Male; Nitrogen; Obesit

1971
[Protein and amino acid excretion in extracorporeal dialysis].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1968, Volume: 49, Issue:6

    Topics: Alanine; Amino Acids; Blood Protein Electrophoresis; Blood Proteins; Deficiency Diseases; Glycine; H

1968
Metabolism of amino acids in protein-calorie-deficient rats.
    The Biochemical journal, 1969, Volume: 111, Issue:4

    Topics: Alanine; Amino Acids; Animals; Caproates; Carbon Isotopes; Caseins; Coenzyme A; Deficiency Diseases;

1969