alanine has been researched along with DDPAC in 6 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we show in the model system Caenorhabditis elegans that expression of the arginine-containing dipeptides, but not alanine-containing dipeptides, produces toxic phenotypes in multiple cellular contexts, including motor neurons." | 1.46 | Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans. ( Lamitina, ST; Monaghan, J; Pandey, UB; Rudich, P; Snoznik, C; Watkins, SC, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sonobe, Y | 1 |
| Aburas, J | 1 |
| Krishnan, G | 1 |
| Fleming, AC | 1 |
| Ghadge, G | 1 |
| Islam, P | 1 |
| Warren, EC | 1 |
| Gu, Y | 1 |
| Kankel, MW | 1 |
| Brown, AEX | 1 |
| Kiskinis, E | 1 |
| Gendron, TF | 1 |
| Gao, FB | 1 |
| Roos, RP | 1 |
| Kratsios, P | 1 |
| Morón-Oset, J | 1 |
| Fischer, LKS | 1 |
| Jauré, N | 1 |
| Zhang, P | 1 |
| Jahn, AJ | 1 |
| Supèr, T | 1 |
| Pahl, A | 1 |
| Isaacs, AM | 1 |
| Grönke, S | 1 |
| Partridge, L | 1 |
| Jensen, BK | 1 |
| Schuldi, MH | 1 |
| McAvoy, K | 1 |
| Russell, KA | 1 |
| Boehringer, A | 1 |
| Curran, BM | 1 |
| Krishnamurthy, K | 1 |
| Wen, X | 1 |
| Westergard, T | 1 |
| Ma, L | 1 |
| Haeusler, AR | 1 |
| Edbauer, D | 2 |
| Pasinelli, P | 1 |
| Trotti, D | 1 |
| Rudich, P | 1 |
| Snoznik, C | 1 |
| Watkins, SC | 1 |
| Monaghan, J | 1 |
| Pandey, UB | 1 |
| Lamitina, ST | 1 |
| Guo, Q | 1 |
| Lehmer, C | 1 |
| Martínez-Sánchez, A | 1 |
| Rudack, T | 1 |
| Beck, F | 1 |
| Hartmann, H | 1 |
| Pérez-Berlanga, M | 1 |
| Frottin, F | 1 |
| Hipp, MS | 1 |
| Hartl, FU | 1 |
| Baumeister, W | 1 |
| Fernández-Busnadiego, R | 1 |
| Kimura, T | 1 |
| Hosokawa, T | 1 |
| Taoka, M | 1 |
| Tsutsumi, K | 1 |
| Ando, K | 1 |
| Ishiguro, K | 1 |
| Hosokawa, M | 1 |
| Hasegawa, M | 1 |
| Hisanaga, S | 1 |
6 other studies available for alanine and DDPAC
| Article | Year |
|---|---|
A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Caenorhabditis elegans; | 2021 |
Repeat length of C9orf72-associated glycine-alanine polypeptides affects their toxicity.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; C9orf72 Protein; Dipeptides; Drosophila; Frontotemp | 2023 |
Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; C9orf72 Protein; Dipeptides; Frontotemporal Dementi | 2020 |
Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans.
Topics: Age Factors; Alanine; Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Caenorhabdi | 2017 |
In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; C9orf72 Protein; Frontotemporal Dementia; HEK293 Ce | 2018 |
Quantitative and combinatory determination of in situ phosphorylation of tau and its FTDP-17 mutants.
Topics: Alanine; Amino Acid Sequence; Animals; Brain; Chlorocebus aethiops; COS Cells; Cyclin-Dependent Kina | 2016 |