alanine has been researched along with Colorectal Neoplasms, Hereditary Nonpolyposis in 1 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Colorectal Neoplasms, Hereditary Nonpolyposis: A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hereditary nonpolyposis colorectal cancer (HNPCC) is caused by mutations in the mismatch-repair genes." | 1.31 | The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population. ( Bonner, JD; Boyd, J; Chong, G; De La Chapelle, A; Ellis, NA; Farber, D; Figer, A; Foulkes, WD; Friedman, E; Gaff, CL; Gebert, J; Gordon, PH; Greenwood, CM; Gregersen, PK; Gruber, SB; Hamel, N; Hampel, H; Horwitz, M; King, MC; Lee, C; MacNamara, E; Macrae, FA; Marcus, V; Markowitz, A; Nafa, K; Offit, K; Paillerets, BB; Rennert, G; Shia, J; Thiffault, I; Tomsho, L; Walsh, T; Weitzel, JN, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Foulkes, WD | 1 |
| Thiffault, I | 1 |
| Gruber, SB | 1 |
| Horwitz, M | 1 |
| Hamel, N | 1 |
| Lee, C | 1 |
| Shia, J | 1 |
| Markowitz, A | 1 |
| Figer, A | 1 |
| Friedman, E | 1 |
| Farber, D | 1 |
| Greenwood, CM | 1 |
| Bonner, JD | 1 |
| Nafa, K | 1 |
| Walsh, T | 1 |
| Marcus, V | 1 |
| Tomsho, L | 1 |
| Gebert, J | 1 |
| Macrae, FA | 1 |
| Gaff, CL | 1 |
| Paillerets, BB | 1 |
| Gregersen, PK | 1 |
| Weitzel, JN | 1 |
| Gordon, PH | 1 |
| MacNamara, E | 1 |
| King, MC | 1 |
| Hampel, H | 1 |
| De La Chapelle, A | 1 |
| Boyd, J | 1 |
| Offit, K | 1 |
| Rennert, G | 1 |
| Chong, G | 1 |
| Ellis, NA | 1 |
1 other study available for alanine and Colorectal Neoplasms, Hereditary Nonpolyposis
| Article | Year |
|---|---|
The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population.
Topics: Alanine; Case-Control Studies; Chromosomes, Human, Pair 2; Colorectal Neoplasms, Hereditary Nonpolyp | 2002 |