Page last updated: 2024-11-08

alanine and Cataract

alanine has been researched along with Cataract in 24 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" In particular, the early tryptophan oxidation product, oxindolealanine (OIA) has been detected in lyophilized and hydrolyzed cataractous lenses by mass spectrometry."7.74Oxindolealanine in age-related human cataracts. ( Dillon, JP; Gaillard, ER; Garland, DL; Merriam, JC; Paik, DC; Rousseva, LA; Ryzhov, V, 2007)
" In particular, the early tryptophan oxidation product, oxindolealanine (OIA) has been detected in lyophilized and hydrolyzed cataractous lenses by mass spectrometry."3.74Oxindolealanine in age-related human cataracts. ( Dillon, JP; Gaillard, ER; Garland, DL; Merriam, JC; Paik, DC; Rousseva, LA; Ryzhov, V, 2007)
"There was a gradual decrease in the quantity of various amino acids associated with cataract formation due to reduced concentrations of glutamic acid, threonine, serine, glycine, alanine, leucine, isoleucine, phenylalanine and tyrosine in stages of cataract formation."3.67Study of the relationship between free amino acids and cataract in human lenses. ( Bhatnagar, R; Chauhan, BS; Desai, NC; Garg, SP, 1984)
"A case of gyrate atrophy of the choroid and retina associated with hyperornithinemia has been subjected to extensive clinical and biochemical investigation."3.65Gyrate atrophy of the choroid and retina: clinical, ophthalmologic, and biochemical considerations. ( Marliss, EB; McCulloch, C, 1975)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19909 (37.50)18.7374
1990's2 (8.33)18.2507
2000's5 (20.83)29.6817
2010's7 (29.17)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Magami, K1
Hachiya, N1
Morikawa, K1
Fujii, N1
Takata, T1
Wang, Z1
Schey, KL1
Jin, H1
Zhu, B1
Liu, X1
Jin, J1
Zou, H1
Yang, Z1
Xia, Z1
Huynh, T1
King, JA1
Zhou, R1
Yoshinaga, T1
Sekijima, Y1
Koyama, S1
Maruyama, K1
Yoshida, T1
Kato, T1
Ikeda, S1
HALL, WK1
BOWLES, LL1
Ma, X1
Li, FF1
Wang, SZ1
Gao, C1
Zhang, M1
Zhu, SQ1
Asherie, N1
Yao, K1
Li, J1
Jin, C1
Wang, W1
Zhu, Y1
Shentu, X1
Wang, Q1
Cooper, AJ1
Pinto, JT1
Callery, PS1
VON SALLMANN, L1
GRIMES, P1
COLLINS, E1
TITTARELLI, R1
CATALINO, P1
Linetsky, M1
Hill, JM1
LeGrand, RD1
Hu, F1
Messina-Baas, OM1
Gonzalez-Huerta, LM1
Cuevas-Covarrubias, SA1
Rousseva, LA1
Gaillard, ER1
Paik, DC1
Merriam, JC1
Ryzhov, V1
Garland, DL1
Dillon, JP1
Fris, M1
Cejková, J1
Midelfart, A1
Chauhan, BS1
Desai, NC1
Bhatnagar, R1
Garg, SP1
Chiarugi, A1
Rapizzi, E1
Moroni, F2
Wilensky, JT1
Goldberg, MF1
Ziyai, F1
Wong, PW1
McCulloch, C1
Marliss, EB1
D'Aniello, A1
D'Onofrio, G1
Pischetola, M1
Bessems, GJ1
Rennen, HJ1
Hoenders, HJ1
Harris, JE1
Gruber, L1
Graeber, W1

Reviews

1 review available for alanine and Cataract

ArticleYear
Reversible and irreversible protein glutathionylation: biological and clinical aspects.
    Expert opinion on drug metabolism & toxicology, 2011, Volume: 7, Issue:7

    Topics: Alanine; Aldehydes; Alzheimer Disease; Apoptosis; Busulfan; Cataract; Cell Cycle; Cystic Fibrosis; D

2011

Other Studies

23 other studies available for alanine and Cataract

ArticleYear
Isomerization of Asp is essential for assembly of amyloid-like fibrils of αA-crystallin-derived peptide.
    PloS one, 2021, Volume: 16, Issue:4

    Topics: Aging; Alanine; alpha-Crystallin A Chain; Amino Acid Sequence; Amino Acid Substitution; Amyloid; Asp

2021
Quantification of thioether-linked glutathione modifications in human lens proteins.
    Experimental eye research, 2018, Volume: 175

    Topics: Adolescent; Alanine; Aminobutyrates; Cataract; Cellular Senescence; Chromatography, Liquid; Crystall

2018
Metabolic characterization of diabetic retinopathy: An
    Journal of pharmaceutical and biomedical analysis, 2019, Sep-10, Volume: 174

    Topics: Aged; Alanine; Antioxidants; Aqueous Humor; Area Under Curve; Aspartic Acid; Cataract; Diabetic Reti

2019
Dissecting the contributions of β-hairpin tyrosine pairs to the folding and stability of long-lived human γD-crystallins.
    Nanoscale, 2014, Volume: 6, Issue:3

    Topics: Alanine; Cataract; Cations; gamma-Crystallins; Humans; Hydrophobic and Hydrophilic Interactions; Kyn

2014
Clinical and radiological findings of a cerebrotendinous xanthomatosis patient with a novel p.A335V mutation in the CYP27A1 gene.
    Internal medicine (Tokyo, Japan), 2014, Volume: 53, Issue:23

    Topics: Achilles Tendon; Alanine; Ataxia; Brain; Cataract; Chenodeoxycholic Acid; Cholestanetriol 26-Monooxy

2014
Cataracts due to deficiencies of phenylalanine and histidine in the rat; a comparison with other types of cataracts.
    The Journal of nutrition, 1948, Volume: 36, Issue:2

    Topics: Alanine; Animals; Cataract; Histidine; Phenylalanine; Rats

1948
A new mutation in BFSP2 (G1091A) causes autosomal dominant congenital lamellar cataracts.
    Molecular vision, 2008, Volume: 14

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Cataract; Child; Chromatograph

2008
Blind attraction: the mechanism of an inherited congenital cataract.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Jan-11, Volume: 108, Issue:2

    Topics: Alanine; Cataract; Crystallins; Genetic Predisposition to Disease; Humans; Lens, Crystalline; Light;

2011
Characterization of a novel mutation in the CRYBB2 gene associated with autosomal dominant congenital posterior subcapsular cataract in a Chinese family.
    Molecular vision, 2011, Jan-13, Volume: 17

    Topics: Alanine; beta-Crystallin B Chain; Cataract; China; DNA Mutational Analysis; Female; Humans; Male; Mu

2011
Mimosine cataract.
    American journal of ophthalmology, 1959, Volume: 47, Issue:5 Pt 2

    Topics: Alanine; Cataract; Mimosine; Plants

1959
[Contribution to the study of experimental cataract induced by leucinol (leucine, momosine)].
    Bollettino d'oculistica, 1961, Volume: 40

    Topics: Alanine; Cataract; Leucine; Pyridines

1961
Dehydroalanine crosslinks in human lens.
    Experimental eye research, 2004, Volume: 79, Issue:4

    Topics: Adult; Aged; Aging; Alanine; Cataract; Chromatography, High Pressure Liquid; Chromatography, Ion Exc

2004
Two affected siblings with nuclear cataract associated with a novel missense mutation in the CRYGD gene.
    Molecular vision, 2006, Aug-24, Volume: 12

    Topics: Adenosine; Adult; Alanine; Amino Acid Substitution; Case-Control Studies; Cataract; Cytosine; Female

2006
Oxindolealanine in age-related human cataracts.
    Experimental eye research, 2007, Volume: 85, Issue:6

    Topics: Aged; Aged, 80 and over; Alanine; alpha-Crystallins; Animals; Biomarkers; Cataract; Cattle; Chromato

2007
The effect of single and repeated UVB radiation on rabbit lens.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2008, Volume: 246, Issue:4

    Topics: Alanine; Animals; Cataract; Glutathione; Inositol; Lens, Crystalline; Nuclear Magnetic Resonance, Bi

2008
Study of the relationship between free amino acids and cataract in human lenses.
    Experimental eye research, 1984, Volume: 38, Issue:2

    Topics: Adult; Aged; Alanine; Amino Acids; Cataract; Glutamates; Glutamic Acid; Glycine; Humans; Lens, Cryst

1984
The kynurenine metabolic pathway in the eye: studies on 3-hydroxykynurenine, a putative cataractogenic compound.
    FEBS letters, 1999, Jun-18, Volume: 453, Issue:1-2

    Topics: Alanine; Animals; Cataract; Ciliary Body; Eye; Hydrolases; Iris; Kynurenine; Kynurenine 3-Monooxygen

1999
Infantile cataracts, Coats' disease, and ketotic hypoglycemia.
    Journal of pediatric ophthalmology, 1976, Volume: 13, Issue:2

    Topics: Acidosis; Alanine; Blood Glucose; Cataract; Cataract Extraction; Fasting; Female; Glaucoma; Humans;

1976
Gyrate atrophy of the choroid and retina: clinical, ophthalmologic, and biochemical considerations.
    Transactions of the American Ophthalmological Society, 1975, Volume: 73

    Topics: Adult; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Atrophy; Cataract; Choroid; Histidin

1975
Total hydrolysis of proteins with strongly reduced racemization of amino acids.
    Biochimica et biophysica acta, 1990, Feb-09, Volume: 1037, Issue:2

    Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Carboxypeptidases; Cataract; Female; Humans; Hydrolysis;

1990
Lanthionine, a protein cross-link in cataractous human lenses.
    Experimental eye research, 1987, Volume: 44, Issue:5

    Topics: Alanine; Amino Acids; Cataract; Crystallins; Cystine; Humans; Sulfides

1987
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
    Investigative ophthalmology, 1973, Volume: 12, Issue:5

    Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cata

1973
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1966, Dec-15, Volume: 171, Issue:3

    Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins;

1966