alanine has been researched along with Cardiomegaly in 9 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the study was to compare, in a rat model of congestive heart failure, the effect of captopril, a selective angiotensin-converting enzyme (ACE; EC 3." | 7.69 | Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril. ( Bralet, J; Gros, C; Lecomte, JM; Marie, C; Mossiat, C; Schwartz, JC, 1994) |
| "The aim of the study was to compare, in a rat model of congestive heart failure, the effect of captopril, a selective angiotensin-converting enzyme (ACE; EC 3." | 3.69 | Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril. ( Bralet, J; Gros, C; Lecomte, JM; Marie, C; Mossiat, C; Schwartz, JC, 1994) |
| "Cardiac hypertrophy is characterized by transcriptional reprogramming of fetal gene expression, and histone deacetylases (HDACs) are tightly linked to the regulation of those genes." | 1.37 | Casein kinase-2α1 induces hypertrophic response by phosphorylation of histone deacetylase 2 S394 and its activation in the heart. ( Cho, YK; Choe, N; Eom, GH; Joung, H; Kee, HJ; Kim, HS; Kim, Y; Ko, JH; Kook, H; Nam, KI; Shin, S, 2011) |
| "Amlodipine did not affect cardiac hypertrophy." | 1.32 | Cardiovascular hypertrophy in diabetic spontaneously hypertensive rats: optimizing blockade of the renin-angiotensin system. ( Allen, TJ; Burrell, LM; Cao, Z; Cooper, ME; Davis, BJ; Lassila, M, 2003) |
| "Myocardial infarction was induced by rats by ligation of the left coronary artery." | 1.29 | Effect on prolonged inhibition of neutral endopeptidase on cardiac hypertrophy in rats with myocardial infarction. ( Bralet, J; Gros, C; Marie, C; Monteil, T; Mossiat, C, 1996) |
| "Taurine is a modifier of calcium fluxes in the heart, as are beta-adrenergic agonists." | 1.26 | Adrenergic stimulation of taurine transport by the heart. ( Chubb, J; Huxtable, R, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eom, GH | 1 |
| Cho, YK | 1 |
| Ko, JH | 1 |
| Shin, S | 1 |
| Choe, N | 1 |
| Kim, Y | 1 |
| Joung, H | 1 |
| Kim, HS | 1 |
| Nam, KI | 1 |
| Kee, HJ | 1 |
| Kook, H | 1 |
| Lassila, M | 1 |
| Davis, BJ | 1 |
| Allen, TJ | 1 |
| Burrell, LM | 1 |
| Cooper, ME | 1 |
| Cao, Z | 1 |
| King, N | 1 |
| Lin, H | 1 |
| McGivan, JD | 1 |
| Suleiman, MS | 1 |
| Lu, H | 1 |
| Fedak, PW | 1 |
| Dai, X | 1 |
| Du, C | 1 |
| Zhou, YQ | 1 |
| Henkelman, M | 1 |
| Mongroo, PS | 1 |
| Lau, A | 1 |
| Yamabi, H | 1 |
| Hinek, A | 1 |
| Husain, M | 1 |
| Hannigan, G | 1 |
| Coles, JG | 1 |
| Bralet, J | 2 |
| Marie, C | 2 |
| Mossiat, C | 2 |
| Lecomte, JM | 1 |
| Gros, C | 2 |
| Schwartz, JC | 1 |
| Monteil, T | 1 |
| Hu, K | 1 |
| Ertl, G | 1 |
| Huxtable, R | 1 |
| Chubb, J | 1 |
| Meerson, FZ | 1 |
| Pomoinitsky, VD | 1 |
9 other studies available for alanine and Cardiomegaly
| Article | Year |
|---|---|
Casein kinase-2α1 induces hypertrophic response by phosphorylation of histone deacetylase 2 S394 and its activation in the heart.
Topics: Alanine; Animals; Cardiomegaly; Cardiomyopathy, Hypertrophic; Casein Kinase II; Enzyme Activation; H | 2011 |
Cardiovascular hypertrophy in diabetic spontaneously hypertensive rats: optimizing blockade of the renin-angiotensin system.
Topics: Alanine; Amiodarone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Ani | 2003 |
Aspartate transporter expression and activity in hypertrophic rat heart and ischaemia-reperfusion injury.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, | 2004 |
Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice.
Topics: Alanine; Angiotensin II; Animals; Arginine; Cardiomegaly; cdc42 GTP-Binding Protein; Enzyme Activati | 2006 |
Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril.
Topics: Alanine; Amino Acid Sequence; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Atri | 1994 |
Effect on prolonged inhibition of neutral endopeptidase on cardiac hypertrophy in rats with myocardial infarction.
Topics: Alanine; Animals; Atrial Natriuretic Factor; Cardiomegaly; Enzyme Inhibitors; Ligation; Male; Myocar | 1996 |
Potential role of mixed ACE and neutral endopeptidase inhibitor in the treatment of heart failure.
Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Cricetinae | 1999 |
Adrenergic stimulation of taurine transport by the heart.
Topics: Alanine; Animals; Biological Transport; Cardiomegaly; Cyclic AMP; Heart; Isoproterenol; Kinetics; My | 1977 |
The role of high-energy phosphate compounds in the development of cardiac hypertrophy.
Topics: Acclimatization; Adenosine Triphosphate; Alanine; Animals; Aorta; Atmosphere Exposure Chambers; Carb | 1972 |