alanine has been researched along with Carcinogenesis in 5 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, using HNSCC cell lines, we examined the anti-cancer effects and the mechanisms of action of docosahexaenoyl ethanolamide (DHEA) and N-arachidonoyl-L-alanine (NALA), which are polyunsaturated fatty acid (PUFA)-based ethanolamides like AEA." | 1.43 | 5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells. ( Hah, JH; Jeong, WJ; Oh, SM; Park, SW; Sung, MW, 2016) |
| "Rb1(+/-) mice develop pituitary tumors with full penetrance and the tumors are invariably Rb1(-/-), modeling tumorigenesis by two-hit loss of RB1 in humans." | 1.42 | Substituting threonine 187 with alanine in p27Kip1 prevents pituitary tumorigenesis by two-hit loss of Rb1 and enhances humoral immunity in old age. ( Bauzon, F; Bi, E; Cui, J; Fu, H; Jeon, H; Lu, Z; Ye, BH; Yu, JJ; Zang, X; Zhao, H; Zhu, L, 2015) |
| "MNNG-induced carcinogenesis and may also inhibit progression of cancer in rats." | 1.42 | Preventive effect of rebamipide on N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats. ( Ebi, M; Hayashi, N; Joh, T; Katano, T; Kataoka, H; Mizoshita, T; Mori, Y; Ozeki, K; Shimura, T; Tanida, S; Tatematsu, M; Tsukamoto, H; Tsukamoto, T, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nagashima, T | 1 |
| Shimizu, K | 1 |
| Matsumoto, R | 1 |
| Honda, H | 1 |
| Zhao, H | 1 |
| Bauzon, F | 1 |
| Bi, E | 1 |
| Yu, JJ | 1 |
| Fu, H | 1 |
| Lu, Z | 1 |
| Cui, J | 1 |
| Jeon, H | 1 |
| Zang, X | 1 |
| Ye, BH | 1 |
| Zhu, L | 1 |
| Tsukamoto, H | 1 |
| Mizoshita, T | 1 |
| Katano, T | 1 |
| Hayashi, N | 1 |
| Ozeki, K | 1 |
| Ebi, M | 1 |
| Shimura, T | 1 |
| Mori, Y | 1 |
| Tanida, S | 1 |
| Kataoka, H | 1 |
| Tsukamoto, T | 1 |
| Tatematsu, M | 1 |
| Joh, T | 1 |
| Park, SW | 1 |
| Hah, JH | 1 |
| Oh, SM | 1 |
| Jeong, WJ | 1 |
| Sung, MW | 1 |
| RUTMAN, RJ | 1 |
| CANTAROW, A | 1 |
| PASCHKIS, KE | 1 |
5 other studies available for alanine and Carcinogenesis
| Article | Year |
|---|---|
Selective Elimination of Human Induced Pluripotent Stem Cells Using Medium with High Concentration of L-Alanine.
Topics: Alanine; Carcinogenesis; Cell Differentiation; Cells, Cultured; Fibroblasts; Humans; Induced Pluripo | 2018 |
Substituting threonine 187 with alanine in p27Kip1 prevents pituitary tumorigenesis by two-hit loss of Rb1 and enhances humoral immunity in old age.
Topics: Age Factors; Alanine; Amino Acid Substitution; Animals; B-Lymphocytes; Carcinogenesis; Cyclin-Depend | 2015 |
Preventive effect of rebamipide on N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats.
Topics: Adenocarcinoma; Alanine; Animals; Antioxidants; Carcinogenesis; Carcinogens; Disease Models, Animal; | 2015 |
5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells.
Topics: Alanine; Antineoplastic Agents; Apoptosis; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Azoles; B | 2016 |
Studies in 2-acetylaminofluorene carcinogenesis. II. The in vitro uptake of alanine-1-C14 by preneoplastic liver and hepatoma mitochondrial protein.
Topics: 2-Acetylaminofluorene; Alanine; Carcinogenesis; Carcinoma, Hepatocellular; Fluorenes; In Vitro Techn | 1954 |