alanine has been researched along with Canine Diseases in 12 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rabacfosadine (RAB, Tanovea-CA1) is a novel chemotherapy agent conditionally approved for the treatment of lymphoma in dogs." | 9.51 | Multicenter, randomized, double-blinded, placebo-controlled study of rabacfosadine in dogs with lymphoma. ( Avery, AC; Bergman, PJ; Christman Hull, AA; Clifford, CA; Donoghue, AR; Gust, CM; McDaniel, JA; Phillips, BS; Post, GS; Randall, EK; Rosenberg, MP; Thamm, DH; Weishaar, KM; Wright, ZM, 2022) |
| "Rabacfosadine (RAB), a novel antineoplastic agent conditionally licensed for the treatment of lymphoma in dogs, is efficacious in both naïve and previously treated dogs." | 7.96 | Concurrent use of rabacfosadine and L-asparaginase for relapsed or refractory multicentric lymphoma in dogs. ( Bergman, PJ; Cawley, JR; Clifford, CA; Meleo, K; Post, GS; Thamm, DH; Vail, DM; Vickery, KR; Wright, ZM, 2020) |
| " Response assessment and adverse event (Ae) evaluation were performed every 21 days via Veterinary Cooperative Oncology Group (VCOG) criteria." | 6.94 | Rabacfosadine for naïve canine intermediate to large cell lymphoma: Efficacy and adverse event profile across three prospective clinical trials. ( Burgess, K; Clifford, C; Curran, K; Elmslie, R; Fan, T; Phillips, B; Post, G; Saba, CF; Thamm, D; Vail, D; Wright, Z, 2020) |
| "Pythiosis is reported in tropical and subtropical climates, affecting dogs and rarely cats." | 5.56 | Mefenoxam, Itraconazole, and Terbinafine Combination Therapy for Management of Pythiosis in Dogs (Six Cases). ( Cridge, H; Hughes, SM; Langston, VC; Mackin, AJ, 2020) |
| "Rabacfosadine (RAB, Tanovea-CA1) is a novel chemotherapy agent conditionally approved for the treatment of lymphoma in dogs." | 5.51 | Multicenter, randomized, double-blinded, placebo-controlled study of rabacfosadine in dogs with lymphoma. ( Avery, AC; Bergman, PJ; Christman Hull, AA; Clifford, CA; Donoghue, AR; Gust, CM; McDaniel, JA; Phillips, BS; Post, GS; Randall, EK; Rosenberg, MP; Thamm, DH; Weishaar, KM; Wright, ZM, 2022) |
| "Rabacfosadine is a generally well tolerated, effective chemotherapy option for dogs with relapsed B-cell lymphoma." | 5.48 | Rabacfosadine for relapsed canine B-cell lymphoma: Efficacy and adverse event profiles of 2 different doses. ( Burgess, KE; Clifford, CA; Fan, TM; Morges, MA; Phillips, B; Saba, CF; Thamm, DH; Vail, DM; Vickery, KR; Wright, ZM, 2018) |
| "Medical therapy for pythiosis is hampered by a lack of efficacious drugs." | 5.37 | Successful management of gastrointestinal pythiosis in a dog using itraconazole, terbinafine, and mefenoxam. ( Birkenheuer, A; Davidson, G; Grooters, A; Hummel, J; Jennings, S; Nicklas, J, 2011) |
| "Rabacfosadine (RAB), a novel antineoplastic agent conditionally licensed for the treatment of lymphoma in dogs, is efficacious in both naïve and previously treated dogs." | 3.96 | Concurrent use of rabacfosadine and L-asparaginase for relapsed or refractory multicentric lymphoma in dogs. ( Bergman, PJ; Cawley, JR; Clifford, CA; Meleo, K; Post, GS; Thamm, DH; Vail, DM; Vickery, KR; Wright, ZM, 2020) |
| " Response assessment and adverse event (Ae) evaluation were performed every 21 days via Veterinary Cooperative Oncology Group (VCOG) criteria." | 2.94 | Rabacfosadine for naïve canine intermediate to large cell lymphoma: Efficacy and adverse event profile across three prospective clinical trials. ( Burgess, K; Clifford, C; Curran, K; Elmslie, R; Fan, T; Phillips, B; Post, G; Saba, CF; Thamm, D; Vail, D; Wright, Z, 2020) |
| "Pythiosis is reported in tropical and subtropical climates, affecting dogs and rarely cats." | 1.56 | Mefenoxam, Itraconazole, and Terbinafine Combination Therapy for Management of Pythiosis in Dogs (Six Cases). ( Cridge, H; Hughes, SM; Langston, VC; Mackin, AJ, 2020) |
| "Rabacfosadine is a generally well tolerated, effective chemotherapy option for dogs with relapsed B-cell lymphoma." | 1.48 | Rabacfosadine for relapsed canine B-cell lymphoma: Efficacy and adverse event profiles of 2 different doses. ( Burgess, KE; Clifford, CA; Fan, TM; Morges, MA; Phillips, B; Saba, CF; Thamm, DH; Vail, DM; Vickery, KR; Wright, ZM, 2018) |
| "Medical therapy for pythiosis is hampered by a lack of efficacious drugs." | 1.37 | Successful management of gastrointestinal pythiosis in a dog using itraconazole, terbinafine, and mefenoxam. ( Birkenheuer, A; Davidson, G; Grooters, A; Hummel, J; Jennings, S; Nicklas, J, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 5 (41.67) | 2.80 |
| Authors | Studies |
|---|---|
| Weishaar, KM | 1 |
| Wright, ZM | 3 |
| Rosenberg, MP | 1 |
| Post, GS | 3 |
| McDaniel, JA | 1 |
| Clifford, CA | 3 |
| Phillips, BS | 2 |
| Bergman, PJ | 2 |
| Randall, EK | 1 |
| Avery, AC | 1 |
| Thamm, DH | 6 |
| Christman Hull, AA | 1 |
| Gust, CM | 1 |
| Donoghue, AR | 1 |
| Cawley, JR | 1 |
| Meleo, K | 1 |
| Vickery, KR | 2 |
| Vail, DM | 5 |
| Saba, CF | 2 |
| Clifford, C | 1 |
| Burgess, K | 1 |
| Phillips, B | 2 |
| Vail, D | 1 |
| Wright, Z | 1 |
| Curran, K | 1 |
| Fan, T | 1 |
| Elmslie, R | 1 |
| Post, G | 1 |
| Thamm, D | 1 |
| Cridge, H | 1 |
| Hughes, SM | 1 |
| Langston, VC | 1 |
| Mackin, AJ | 1 |
| Fan, TM | 2 |
| Axiak-Bechtel, S | 1 |
| Elmslie, RS | 1 |
| Klein, MK | 1 |
| Ruslander, DA | 1 |
| Burgess, KE | 1 |
| Morges, MA | 1 |
| Kurzman, ID | 2 |
| Babusis, D | 2 |
| Ray, AS | 2 |
| Sousa-Powers, N | 1 |
| Tumas, DB | 2 |
| Reiser, H | 1 |
| Wolfgang, GH | 1 |
| Watkins, WJ | 1 |
| Henne, IN | 1 |
| Hawkins, MJ | 1 |
| Jeraj, R | 1 |
| Vanderhoek, M | 1 |
| Plaza, S | 1 |
| Anderson, C | 1 |
| Wessel, MA | 1 |
| Robat, C | 1 |
| Lawrence, J | 1 |
| Hummel, J | 1 |
| Grooters, A | 1 |
| Davidson, G | 1 |
| Jennings, S | 1 |
| Nicklas, J | 1 |
| Birkenheuer, A | 1 |
| Holt, DE | 1 |
| Washabau, RJ | 1 |
| Djali, S | 1 |
| Dayrell-Hart, B | 1 |
| Drobatz, KJ | 1 |
| Heyes, MP | 1 |
| Robinson, MB | 1 |
| Meyer, ME | 1 |
3 trials available for alanine and Canine Diseases
| Article | Year |
|---|---|
Multicenter, randomized, double-blinded, placebo-controlled study of rabacfosadine in dogs with lymphoma.
Topics: Alanine; Animals; Antineoplastic Combined Chemotherapy Protocols; Dog Diseases; Dogs; Lymphoma; Puri | 2022 |
Rabacfosadine for naïve canine intermediate to large cell lymphoma: Efficacy and adverse event profile across three prospective clinical trials.
Topics: Alanine; Animals; Dog Diseases; Dogs; Female; Lymphoma; Male; Purines; Treatment Outcome | 2020 |
GS-9219/VDC-1101--a prodrug of the acyclic nucleotide PMEG has antitumor activity in spontaneous canine multiple myeloma.
Topics: Alanine; Animals; Antineoplastic Agents; Cell Line, Tumor; Dog Diseases; Dogs; Female; Guanine; Huma | 2014 |
9 other studies available for alanine and Canine Diseases
| Article | Year |
|---|---|
Topics: Alanine; Animals; Dog Diseases; Dogs; Lymphoma; Purines | 2022 |
Concurrent use of rabacfosadine and L-asparaginase for relapsed or refractory multicentric lymphoma in dogs.
Topics: Alanine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginas | 2020 |
Mefenoxam, Itraconazole, and Terbinafine Combination Therapy for Management of Pythiosis in Dogs (Six Cases).
Topics: 14-alpha Demethylase Inhibitors; Alanine; Animals; Antifungal Agents; Dog Diseases; Dogs; Drug Thera | 2020 |
Alternating Rabacfosadine/Doxorubicin: Efficacy and Tolerability in Naïve Canine Multicentric Lymphoma.
Topics: Alanine; Animals; Antineoplastic Agents; Dog Diseases; Dogs; Doxorubicin; Drug Administration Schedu | 2017 |
Rabacfosadine for relapsed canine B-cell lymphoma: Efficacy and adverse event profiles of 2 different doses.
Topics: Alanine; Animals; Antineoplastic Agents; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Lymph | 2018 |
Assessment of GS-9219 in a pet dog model of non-Hodgkin's lymphoma.
Topics: Alanine; Animals; Animals, Domestic; Anorexia; Antineoplastic Agents; Area Under Curve; Diarrhea; Di | 2009 |
Successful management of gastrointestinal pythiosis in a dog using itraconazole, terbinafine, and mefenoxam.
Topics: Alanine; Animals; Antifungal Agents; Dog Diseases; Dogs; Duodenum; Female; Gastrointestinal Diseases | 2011 |
Cerebrospinal fluid glutamine, tryptophan, and tryptophan metabolite concentrations in dogs with portosystemic shunts.
Topics: Alanine; Animals; Dietary Proteins; Dog Diseases; Dogs; Female; Glutamine; Hepatic Encephalopathy; H | 2002 |
Brucella organisms isolated from dogs: comparison of characteristics of members of the genus Brucella.
Topics: Abortion, Veterinary; Alanine; Animals; Arabinose; Arginine; Asparagine; Brucella; Brucellosis; Citr | 1969 |