alanine has been researched along with Cancer of Gastrointestinal Tract in 7 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Assessments included adverse events, PK, tumour response, 2[18F]fluoro-2-deoxyglucose positron-emitting tomography and K-Ras mutation analyses." | 2.76 | Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy. ( Buter, J; Chemidlin, J; El-Khoueiry, A; Feltquate, D; Ford, S; Galbraith, S; Garrett, CR; Hayes, W; Kollia, G; LoRusso, P; Major, P; Marshall, J; Mokliatchouk, O; Nuyten, DS; Rocha-Lima, CM; Siu, LL; Syed, S; Velasquez, L, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garrett, CR | 1 |
| Siu, LL | 1 |
| El-Khoueiry, A | 1 |
| Buter, J | 1 |
| Rocha-Lima, CM | 1 |
| Marshall, J | 1 |
| LoRusso, P | 1 |
| Major, P | 1 |
| Chemidlin, J | 1 |
| Mokliatchouk, O | 1 |
| Velasquez, L | 1 |
| Hayes, W | 1 |
| Feltquate, D | 1 |
| Syed, S | 1 |
| Ford, S | 1 |
| Kollia, G | 1 |
| Galbraith, S | 1 |
| Nuyten, DS | 1 |
| Gusella, M | 1 |
| Bertolaso, L | 1 |
| Bolzonella, C | 1 |
| Pasini, F | 1 |
| Padrini, R | 1 |
| Bozzetti, F | 1 |
| Terno, G | 1 |
| Baticci, F | 1 |
| Pupa, A | 1 |
| Bonalumi, MG | 1 |
| Sequeira, C | 1 |
| Del Vecchio, M | 1 |
| Camerini, E | 1 |
| Bombardieri, E | 1 |
| Emanuelli, H | 1 |
| Gil, J | 1 |
| Yamamoto, H | 1 |
| Zapata, JM | 1 |
| Reed, JC | 1 |
| Perucho, M | 1 |
| Kubota, A | 1 |
| Meguid, MM | 1 |
| Hitch, DC | 1 |
| Hartl, W | 1 |
| Jauch, KW | 1 |
| Herndon, DN | 1 |
| Cohnert, TU | 1 |
| Wolfe, RR | 1 |
| Schildberg, FW | 1 |
| Bojan, O | 1 |
| Mustea, I | 1 |
| Preda, N | 1 |
2 trials available for alanine and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy.
Topics: Adult; Aged; Alanine; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agen | 2011 |
Effect of low-dose bradykinin on glucose metabolism and nitrogen balance in surgical patients.
Topics: Adolescent; Adult; Alanine; Bradykinin; Breath Tests; Burns; Drug Evaluation; Gastrointestinal Neopl | 1990 |
5 other studies available for alanine and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Frequency of uridine monophosphate synthase Gly(213)Ala polymorphism in Caucasian gastrointestinal cancer patients and healthy subjects, investigated by means of new, rapid genotyping assays.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Amino Acid Substitution; Carcinoma; Chromatography, High Pr | 2011 |
Effect of different caloric substrates on postoperative protein metabolism.
Topics: Aged; Alanine; Amino Acids; Female; Gastrointestinal Neoplasms; Glucagon; Glucose; Humans; Insulin; | 1980 |
Impairment of the proapoptotic activity of Bax by missense mutations found in gastrointestinal cancers.
Topics: Alanine; Amino Acid Substitution; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Biological T | 1999 |
Amino acid profiles correlate diagnostically with organ site in three kinds of malignant tumors.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Arginine; Breast Neoplasms; Ca | 1992 |
[Modification of some free amino acids in the serum of cancer patients under the influence of glucose on tumoral metabolism].
Topics: Alanine; Amino Acids; Breast Neoplasms; Chromatography, Paper; Dietary Carbohydrates; Dietary Protei | 1969 |