alanine has been researched along with Brain Edema in 8 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mice resistant to cerebral malaria were infected with P." | 1.34 | Magnetic resonance spectroscopy reveals an impaired brain metabolic profile in mice resistant to cerebral malaria infected with Plasmodium berghei ANKA. ( Coltel, N; Confort-Gouny, S; Cozzone, PJ; Dalmasso, C; Grau, GE; Gulian, JM; Kober, F; Le Fur, Y; Liprandi, A; Penet, MF; Viola, A, 2007) |
| "Myo-inositol levels were strongly decreased already at 3h after treatment with NH4Cl; other intracellular osmolytes, such as hypotaurine and choline-containing compounds were also decreased, along with a concomitant increase of both the total concentration and the amount of newly synthesized glutamine, alanine, and glutathione." | 1.33 | Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response. ( Leibfritz, D; Zwingmann, C, 2005) |
| "Taurine release was most affected, exhibiting a greater than 9-fold increase during the hyposmotic stimulus." | 1.30 | Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases. ( Estevez, AY; O'Regan, MH; Phillis, JW; Song, D, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carlson, C | 1 |
| Estergard, W | 1 |
| Oh, J | 1 |
| Suhy, J | 1 |
| Jack, CR | 1 |
| Siemers, E | 1 |
| Barakos, J | 1 |
| Righi, V | 1 |
| Tugnoli, V | 1 |
| Mucci, A | 1 |
| Bacci, A | 1 |
| Bonora, S | 1 |
| Schenetti, L | 1 |
| Alexander, JJ | 1 |
| Zwingmann, C | 2 |
| Quigg, R | 1 |
| Leibfritz, D | 1 |
| Penet, MF | 1 |
| Kober, F | 1 |
| Confort-Gouny, S | 1 |
| Le Fur, Y | 1 |
| Dalmasso, C | 1 |
| Coltel, N | 1 |
| Liprandi, A | 1 |
| Gulian, JM | 1 |
| Grau, GE | 1 |
| Cozzone, PJ | 1 |
| Viola, A | 1 |
| Kuchiwaki, H | 1 |
| Inao, S | 1 |
| Yamamoto, M | 1 |
| Yoshida, K | 1 |
| Sugita, K | 1 |
| Estevez, AY | 1 |
| O'Regan, MH | 1 |
| Song, D | 1 |
| Phillis, JW | 1 |
| Yuan, F | 1 |
| Wang, TY | 1 |
| Xu, LX | 1 |
| Sun, YL | 1 |
| Luo, L | 1 |
| Qu, BQ | 1 |
1 trial available for alanine and Brain Edema
| Article | Year |
|---|---|
Prevalence of asymptomatic vasogenic edema in pretreatment Alzheimer's disease study cohorts from phase 3 trials of semagacestat and solanezumab.
Topics: Aged; Aged, 80 and over; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protei | 2011 |
7 other studies available for alanine and Brain Edema
| Article | Year |
|---|---|
MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma.
Topics: 3-Hydroxybutyric Acid; Alanine; Aspartic Acid; Brain Edema; Choline; Creatine; Glutamic Acid; Glutat | 2012 |
MRL/lpr mice have alterations in brain metabolism as shown with [1H-13C] NMR spectroscopy.
Topics: Alanine; Amino Acids; Animals; Brain; Brain Diseases, Metabolic; Brain Edema; Carbon Radioisotopes; | 2005 |
Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response.
Topics: Alanine; Amino Acids; Ammonia; Ammonium Chloride; Animals; Animals, Newborn; Astrocytes; Brain Edema | 2005 |
Magnetic resonance spectroscopy reveals an impaired brain metabolic profile in mice resistant to cerebral malaria infected with Plasmodium berghei ANKA.
Topics: Alanine; Anemia; Animals; Brain; Brain Diseases; Brain Edema; Brain Ischemia; Cell Proliferation; Ce | 2007 |
An assessment of progression of brain edema with amino acid levels in cerebrospinal fluid and changes in electroencephalogram in an adult cat model of cold brain injury.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cats | 1994 |
Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
Topics: Acetophenones; Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Brain Edema; Cerebra | 1999 |
Neurotoxic effect of high dose of L-(+)-2-amino-3-phosphonopropionic acid in rats after intracaudatal injection.
Topics: Alanine; Animals; Astrocytes; Blood-Brain Barrier; Brain Edema; Calcium; Caudate Nucleus; Excitatory | 2001 |