Page last updated: 2024-11-08

alanine and Autosomal Hemophilia A

alanine has been researched along with Autosomal Hemophilia A in 8 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"Acquired hemophilia A (AHA) is a severe life-threatening autoimmune disease due to the development of autoantibodies that neutralize the procoagulant activity of factor VIII (FVIII)."1.38The IgG autoimmune response in postpartum acquired hemophilia A targets mainly the A1a1 domain of FVIII. ( Ali, T; Balicchi, J; Borg, JY; Cayzac, C; Granier, C; Gruel, Y; Lapalud, P; Lavigne-Lissalde, G; Levesque, H; Mathieu-Dupas, E; Pfeiffer, C; Schved, JF, 2012)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nand, S1
Barton, K1
Schultz, R1
Klein, M1
Kini, A1
Lapalud, P1
Ali, T1
Cayzac, C1
Mathieu-Dupas, E1
Levesque, H1
Pfeiffer, C1
Balicchi, J1
Gruel, Y1
Borg, JY1
Schved, JF1
Granier, C1
Lavigne-Lissalde, G1
d'Oiron, R1
Lavergne, JM1
Lavend'homme, R1
Benhida, A1
Bordet, JC1
Negrier, C1
Peerlinck, K1
Vermylen, J1
Saint-Remy, JM1
Jacquemin, M1
Stürzebecher, J1
Klessen, C1
Jaye, M1
de la Salle, H1
Schamber, F1
Balland, A1
Kohli, V1
Findeli, A1
Tolstoshev, P1
Lecocq, JP1
Lubin, IM1
Healey, JF1
Barrow, RT1
Scandella, D1
Lollar, P1
Spitzer, SG1
Kuppuswamy, MN1
Saini, R1
Kasper, CK1
Birktoft, JJ1
Bajaj, SP1
Brinkhous, KM1
Wagner, RH1
Roberts, HR1
Webster, WP1

Other Studies

8 other studies available for alanine and Autosomal Hemophilia A

ArticleYear
Heckathorn disease revisited.
    Blood, 2014, Feb-27, Volume: 123, Issue:9

    Topics: Adult; Alanine; Amino Acid Substitution; Factor VIII; Female; Glutamine; Hemophilia A; Humans; Male;

2014
The IgG autoimmune response in postpartum acquired hemophilia A targets mainly the A1a1 domain of FVIII.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Factor VIII; Female; Hemophilia A; Humans; Immunoglobulin G

2012
Deletion of alanine 2201 in the FVIII C2 domain results in mild hemophilia A by impairing FVIII binding to VWF and phospholipids and destroys a major FVIII antigenic determinant involved in inhibitor development.
    Blood, 2004, Jan-01, Volume: 103, Issue:1

    Topics: Alanine; Antibodies, Monoclonal; Case-Control Studies; Epitopes; Factor VIII; Hemophilia A; Humans;

2004
[Use of synthetic inhibitors in coagulation physiological tests with peptide substrates].
    Folia haematologica (Leipzig, Germany : 1928), 1982, Volume: 109, Issue:1

    Topics: Alanine; Amidines; Benzamidines; Dextrans; Enzyme Activation; Factor X; Factor Xa; Factor XII Defici

1982
Isolation of a human anti-haemophilic factor IX cDNA clone using a unique 52-base synthetic oligonucleotide probe deduced from the amino acid sequence of bovine factor IX.
    Nucleic acids research, 1983, Apr-25, Volume: 11, Issue:8

    Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Cattle; Cloning, Molecular; Codon; DNA; Factor

1983
Analysis of the human factor VIII A2 inhibitor epitope by alanine scanning mutagenesis.
    The Journal of biological chemistry, 1997, Nov-28, Volume: 272, Issue:48

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Autoimmune D

1997
Factor IXHollywood: substitution of Pro55 by Ala in the first epidermal growth factor-like domain.
    Blood, 1990, Oct-15, Volume: 76, Issue:8

    Topics: Alanine; Amino Acid Sequence; Base Sequence; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Res

1990
Use of aliphatic amino acid precipitated antihemophilic factor in therapy of hemophilia.
    Bibliotheca haematologica, 1968, Volume: 29

    Topics: Adult; Alanine; Amino Acids; Chemical Precipitation; Factor VIII; Glycine; Hemophilia A; Humans; Mal

1968