alanine has been researched along with Ataxia with Lactic Acidosis in 7 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Permanent metabolic acidosis due to lactic acidemia as well as hyperpyruvic acidemia and hyperalaninemia were present." | 3.66 | [Pyruvate-dehydrogenase deficiency. Lethal course of the disease during infancy (author's transl)]. ( Becker, K; Berger, R; Bremer, HJ; Przyrembel, H; Walther, B; Wendel, U, 1978) |
| " They had chronic metabolic acidosis associated with elevated blood levels of lactate, pyruvate, and alanine." | 3.65 | Lactic acidosis in three sibs due to defects in both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes. ( Blass, JP; Hansen, S; Haworth, JC; Perry, TL; Urquhart, N, 1976) |
| "Thiamine treatment (1." | 1.26 | Thiamine dependency in a patient with congenital lacticacidaemia due to pyruvate dehydrogenase deficiency. ( Baumgartner, R; Schweizer, K; Wick, H, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Artuch, R | 1 |
| Pineda, M | 1 |
| Vilaseca, MA | 1 |
| Briones, P | 1 |
| Ribes, A | 1 |
| Colomer, J | 1 |
| Vernet, A | 1 |
| Campistol, J | 1 |
| Rubio-Gozalbo, ME | 1 |
| Heerschap, A | 1 |
| Trijbels, JM | 1 |
| De Meirleir, L | 1 |
| Thijssen, HO | 1 |
| Smeitink, JA | 1 |
| DeVivo, DC | 1 |
| Haymond, MW | 1 |
| Obert, KA | 1 |
| Nelson, JS | 1 |
| Pagliara, AS | 1 |
| Haworth, JC | 1 |
| Perry, TL | 1 |
| Blass, JP | 2 |
| Hansen, S | 1 |
| Urquhart, N | 1 |
| Wick, H | 1 |
| Schweizer, K | 1 |
| Baumgartner, R | 1 |
| Wendel, U | 1 |
| Przyrembel, H | 1 |
| Becker, K | 1 |
| Walther, B | 1 |
| Berger, R | 1 |
| Bremer, HJ | 1 |
| Falk, RE | 1 |
| Cederbaum, SD | 1 |
| Gibson, GE | 1 |
| Kark, RA | 1 |
| Carrel, RE | 1 |
7 other studies available for alanine and Ataxia with Lactic Acidosis
| Article | Year |
|---|---|
[Respiratory chain and pyruvate metabolism deficiencies in pediatric patients: evaluation of biochemical tests for selective screening].
Topics: Alanine; Amino Acids; Carnitine; Child; Child, Preschool; Chromatography, Gas; Citric Acid Cycle; DN | 1998 |
Proton MR spectroscopy in a child with pyruvate dehydrogenase complex deficiency.
Topics: Alanine; Aspartic Acid; Binding Sites; Brain; Choline; Corpus Striatum; Creatine; Humans; Infant; La | 1999 |
Defective activation of the pyruvate dehydrogenase complex in subacute necrotizing encephalomyelopathy (Leigh disease).
Topics: Alanine; Blood Glucose; Brain; Brain Diseases; Decarboxylation; Dichloroacetic Acid; Enzyme Activati | 1979 |
Lactic acidosis in three sibs due to defects in both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes.
Topics: Acidosis; Alanine; Carbohydrate Metabolism, Inborn Errors; Electron Transport Complex IV; Female; Gl | 1976 |
Thiamine dependency in a patient with congenital lacticacidaemia due to pyruvate dehydrogenase deficiency.
Topics: Alanine; Fibroblasts; Fructose; Glucagon; Glucose; Humans; Infant; Lactates; Male; Pyruvate Dehydrog | 1977 |
[Pyruvate-dehydrogenase deficiency. Lethal course of the disease during infancy (author's transl)].
Topics: Acidosis; Alanine; Carbohydrate Metabolism, Inborn Errors; Female; Humans; Infant; Infant, Newborn; | 1978 |
Ketonic diet in the management of pyruvate dehydrogenase deficiency.
Topics: Alanine; Carbohydrate Metabolism, Inborn Errors; Child; Citrates; Dietary Carbohydrates; Dietary Fat | 1976 |