alanine and Anxiety
alanine has been researched along with Anxiety in 10 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we compared the efficacy of DZP with that of UBP302 [(S)-3-(2-carboxybenzyl)willardiine; an antagonist of the kainate receptors that contain the GluK1 subunit] against seizures, neuropathology, and behavioral deficits induced by soman in rats." | 7.80 | The limitations of diazepam as a treatment for nerve agent-induced seizures and neuropathology in rats: comparison with UBP302. ( Apland, JP; Aroniadou-Anderjaska, V; Braga, MF; Figueiredo, TH; Miller, SL; Rossetti, F, 2014) |
| " Mice treated with PGW5 (25 and 50mg/kg/d) for 28 days did not show toxic effects in terms of weight gain and blood-chemistry analysis." | 5.40 | A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia. ( Bidder, M; Gil-Ad, I; Kramer, M; Portnoy, M; Taler, M; Tarasenko, I; Weizman, A, 2014) |
| " Here, we compared the efficacy of DZP with that of UBP302 [(S)-3-(2-carboxybenzyl)willardiine; an antagonist of the kainate receptors that contain the GluK1 subunit] against seizures, neuropathology, and behavioral deficits induced by soman in rats." | 3.80 | The limitations of diazepam as a treatment for nerve agent-induced seizures and neuropathology in rats: comparison with UBP302. ( Apland, JP; Aroniadou-Anderjaska, V; Braga, MF; Figueiredo, TH; Miller, SL; Rossetti, F, 2014) |
| "The α(2)δ auxiliary subunits (α(2)δ-1 and α(2)δ-2) of voltage-sensitive calcium channels are thought to be the site of action of pregabalin (Lyrica), a drug that has been shown to be anxiolytic in clinical trials for generalized anxiety disorder." | 3.77 | Anxiolytic-like activity of pregabalin in the Vogel conflict test in α2δ-1 (R217A) and α2δ-2 (R279A) mouse mutants. ( Donevan, S; El-Kattan, A; Lotarski, SM; Offord, J; Osgood, S; Poe, J; Taylor, CP, 2011) |
| " Mice treated with PGW5 (25 and 50mg/kg/d) for 28 days did not show toxic effects in terms of weight gain and blood-chemistry analysis." | 1.40 | A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia. ( Bidder, M; Gil-Ad, I; Kramer, M; Portnoy, M; Taler, M; Tarasenko, I; Weizman, A, 2014) |
Research
Studies (10)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Lu, L | 1 |
| Zheng, X | 1 |
| Wang, S | 1 |
| Tang, C | 1 |
| Zhang, Y | 1 |
| Yao, G | 1 |
| Zeng, J | 1 |
| Ge, S | 1 |
| Wen, H | 1 |
| Xu, M | 1 |
| Guyatt, G | 1 |
| Xu, N | 1 |
| Marxreiter, F | 1 |
| Ettle, B | 1 |
| May, VE | 1 |
| Esmer, H | 1 |
| Patrick, C | 1 |
| Kragh, CL | 1 |
| Klucken, J | 1 |
| Winner, B | 1 |
| Riess, O | 1 |
| Winkler, J | 1 |
| Masliah, E | 1 |
| Nuber, S | 1 |
| Gil-Ad, I | 1 |
| Portnoy, M | 1 |
| Tarasenko, I | 1 |
| Bidder, M | 1 |
| Kramer, M | 1 |
| Taler, M | 1 |
| Weizman, A | 1 |
| Apland, JP | 1 |
| Aroniadou-Anderjaska, V | 1 |
| Figueiredo, TH | 1 |
| Rossetti, F | 1 |
| Miller, SL | 1 |
| Braga, MF | 1 |
| Francisco, Eda S | 1 |
| Guedes, RC | 1 |
| Lo Iacono, L | 1 |
| Gross, C | 1 |
| Graham, DR | 1 |
| Sidhu, A | 1 |
| Lotarski, SM | 1 |
| Donevan, S | 1 |
| El-Kattan, A | 1 |
| Osgood, S | 1 |
| Poe, J | 1 |
| Taylor, CP | 1 |
| Offord, J | 1 |
| Danysz, W | 1 |
| Acosta, GB | 1 |
Reviews
2 reviews available for alanine and Anxiety
| Article | Year |
|---|---|
Anti-Aβ agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis.
Topics: Acitretin; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Antibodies, Monoclonal, Humanized; Anx | 2020 |
LY-544344. Eli Lilly.
Topics: Alanine; Animals; Anti-Anxiety Agents; Anxiety; Bridged Bicyclo Compounds; Clinical Trials as Topic; | 2005 |
Other Studies
8 other studies available for alanine and Anxiety
| Article | Year |
|---|---|
Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice.
Topics: Alanine; alpha-Synuclein; Animals; Anxiety; Avoidance Learning; Cell Count; Disease Models, Animal; | 2013 |
A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia.
Topics: Alanine; Amphetamine; Animals; Antipsychotic Agents; Anxiety; Benzodiazepines; Brain; Central Nervou | 2014 |
The limitations of diazepam as a treatment for nerve agent-induced seizures and neuropathology in rats: comparison with UBP302.
Topics: Alanine; Amygdala; Animals; Anticonvulsants; Anxiety; Diazepam; Hippocampus; Male; Nerve Degeneratio | 2014 |
Neonatal taurine and alanine modulate anxiety-like behavior and decelerate cortical spreading depression in rats previously suckled under different litter sizes.
Topics: Alanine; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Cortical Spreading Depression; Litter | 2015 |
Alpha-Ca2+/calmodulin-dependent protein kinase II contributes to the developmental programming of anxiety in serotonin receptor 1A knock-out mice.
Topics: Actins; Alanine; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Calcium | 2008 |
Mice expressing the A53T mutant form of human alpha-synuclein exhibit hyperactivity and reduced anxiety-like behavior.
Topics: Age Factors; Alanine; alpha-Synuclein; Analysis of Variance; Animals; Anxiety; Disease Models, Anima | 2010 |
Anxiolytic-like activity of pregabalin in the Vogel conflict test in α2δ-1 (R217A) and α2δ-2 (R279A) mouse mutants.
Topics: Alanine; Animals; Anti-Anxiety Agents; Anxiety; Arginine; Calcium Channels; Conflict, Psychological; | 2011 |
Administration of cholecystokinin sulphated octapeptide (CCK-8S) induces changes on rat amino acid tissue levels and on a behavioral test for anxiety.
Topics: Alanine; Amino Acids; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain; Cerebral Corte | 1998 |