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alanine and Angina at Rest

alanine has been researched along with Angina at Rest in 15 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
" Orbofiban, despite no significant excess risk of ICH, was not effective in preventing ischemic stroke or TIA."9.12Risk factors for stroke after acute coronary syndromes in the Orbofiban in Patients with Unstable Coronary Syndromes--Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study. ( Cannon, CP; Feske, SK; Murphy, S; Schwamm, LH; Smith, EE, 2006)
"Thrombocytopenia, though uncommon, was associated with orbofiban use and an increased risk of bleeding, but also death and MI."9.12Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial. ( Aster, RH; Brassard, J; Braunwald, E; Cannon, CP; Charlesworth, A; Cooper, R; McCabe, CH; Scirica, BM; Skene, AM, 2006)
" Orbofiban, despite no significant excess risk of ICH, was not effective in preventing ischemic stroke or TIA."5.12Risk factors for stroke after acute coronary syndromes in the Orbofiban in Patients with Unstable Coronary Syndromes--Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study. ( Cannon, CP; Feske, SK; Murphy, S; Schwamm, LH; Smith, EE, 2006)
"Thrombocytopenia, though uncommon, was associated with orbofiban use and an increased risk of bleeding, but also death and MI."5.12Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial. ( Aster, RH; Brassard, J; Braunwald, E; Cannon, CP; Charlesworth, A; Cooper, R; McCabe, CH; Scirica, BM; Skene, AM, 2006)
" The 2 populations studied were as follows: (1) a cross-sectional study of 703 acute coronary syndrome (ACS) patients with myocardial infarction (MI) and unstable angina, and (2) a prospective study of 924 Caucasian patients from the OPUS (Orbofiban in Patients with Unstable coronary Syndromes)-TIMI-16 trial of the oral GPIIb/IIIa antagonist orbofiban."5.10Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease. ( Fitzgerald, A; Fitzgerald, DJ; Muckian, C; O'Byrne, A; O'Neill, A; Shields, DC, 2002)
" Oral GP IIb/IIIa inhibitors have been associated with an increased incidence of bleeding, but additional experience may permit the design of dosing regimens that decrease this risk."1.31Learning from the recently completed oral glycoprotein IIb/IIIa receptor antagonist trials. ( Cannon, CP, 2000)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's0 (0.00)18.2507
2000's14 (93.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Muckian, C1
Fitzgerald, A2
O'Neill, A1
O'Byrne, A1
Fitzgerald, DJ4
Shields, DC2
Cantor, WJ1
Goodman, SG1
Cannon, CP7
Murphy, SA1
Charlesworth, A2
Braunwauld, E1
Langer, A1
Mager, DE1
Shirey, JD1
Cox, D2
Abernethy, DR1
Smith, EE1
Murphy, S2
Feske, SK1
Schwamm, LH1
Scirica, BM2
Cooper, R1
Aster, RH1
Brassard, J1
McCabe, CH3
Skene, AM1
Braunwald, E4
San Miguel Hernández, A1
Inglada-Galiana, L1
García Iglesias, R1
Alonso Castillejos, N1
Martín Gil, FJ1
Morrow, DA1
de Lemos, JA1
Sabatine, MS1
Wiviott, SD1
Rifai, N1
Newby, LK1
McGuire, DK1
Bhatt, DL1
Topol, EJ1
Smith, R1
Quinn, M1
Theroux, P1
Crean, P1
Wilcox, RG1
Bentley, JH1
Anders, R1
Kleiman, J1
Nicholson, N1
Wazowicz, B1
Burns, D1
O'Connor, FF1
Tashchuk, VK1
Shumakov, VA1
Malinovskaia, IE1

Reviews

3 reviews available for alanine and Angina at Rest

ArticleYear
Oral platelet glycoprotein IIb/IIIa inhibition.
    Current cardiology reports, 2000, Volume: 2, Issue:5

    Topics: Alanine; Angina, Unstable; Aspirin; Benzamidines; Clinical Trials, Phase II as Topic; Clinical Trial

2000
Current role of platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes.
    JAMA, 2000, Sep-27, Volume: 284, Issue:12

    Topics: Abciximab; Acute Disease; Alanine; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Mon

2000
Xemilofiban/orbofiban: insight into drug development.
    Cardiovascular drug reviews, 2001,Summer, Volume: 19, Issue:2

    Topics: Alanine; Angina, Unstable; Animals; Benzamidines; Bleeding Time; Clinical Trials, Phase II as Topic;

2001

Trials

8 trials available for alanine and Angina at Rest

ArticleYear
Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease.
    Blood, 2002, Aug-15, Volume: 100, Issue:4

    Topics: Alanine; Alleles; Angina, Unstable; Collagen; Collagen Type III; Coronary Disease; Cross-Sectional S

2002
Early cardiac catheterization is associated with lower mortality only among high-risk patients with ST- and non-ST-elevation acute coronary syndromes: observations from the OPUS-TIMI 16 trial.
    American heart journal, 2005, Volume: 149, Issue:2

    Topics: Aged; Alanine; Angina, Unstable; Angioplasty, Balloon, Coronary; Cardiac Catheterization; Coronary A

2005
Risk factors for stroke after acute coronary syndromes in the Orbofiban in Patients with Unstable Coronary Syndromes--Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study.
    American heart journal, 2006, Volume: 151, Issue:2

    Topics: Aged; Alanine; Angina, Unstable; Aspirin; Cerebral Hemorrhage; Female; Fibrinolytic Agents; Follow-U

2006
Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial.
    Journal of thrombosis and thrombolysis, 2006, Volume: 22, Issue:2

    Topics: Aged; Alanine; Angina, Unstable; Aspirin; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged;

2006
Clinical application of C-reactive protein across the spectrum of acute coronary syndromes.
    Clinical chemistry, 2007, Volume: 53, Issue:10

    Topics: Acute Disease; Aged; Alanine; Angina Pectoris; Angina, Unstable; C-Reactive Protein; Coronary Diseas

2007
Evidence of platelet activation during treatment with a GPIIb/IIIa antagonist in patients presenting with acute coronary syndromes.
    Journal of the American College of Cardiology, 2000, Nov-01, Volume: 36, Issue:5

    Topics: Acute Disease; Aged; Alanine; Angina, Unstable; Female; Humans; Male; Myocardial Infarction; Platele

2000
Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris. OPUS-TIMI 16 Investigators.
    The American journal of cardiology, 2001, Mar-01, Volume: 87, Issue:5

    Topics: Aged; Alanine; Angina, Unstable; Female; Follow-Up Studies; Humans; Leukocyte Count; Male; Middle Ag

2001
Genetic variation in glycoprotein IIb/IIIa (GPIIb/IIIa) as a determinant of the responses to an oral GPIIb/IIIa antagonist in patients with unstable coronary syndromes.
    Blood, 2001, Dec-01, Volume: 98, Issue:12

    Topics: Aged; Alanine; Angina, Unstable; Antigens, Human Platelet; Aspirin; Double-Blind Method; Female; Gen

2001

Other Studies

4 other studies available for alanine and Angina at Rest

ArticleYear
Mapping the dose-effect relationship of orbofiban from sparse data with an artificial neural network.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:11

    Topics: Alanine; Angina, Unstable; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Male;

2005
[Soluble CD40 ligand: a potential marker of cardiovascular risk].
    Revista clinica espanola, 2007, Volume: 207, Issue:8

    Topics: Abciximab; Acute Coronary Syndrome; Alanine; Angina, Unstable; Animals; Antibodies, Monoclonal; Anti

2007
Learning from the recently completed oral glycoprotein IIb/IIIa receptor antagonist trials.
    Clinical cardiology, 2000, Volume: 23 Suppl 6

    Topics: Alanine; Angina, Unstable; Benzamidines; Humans; Myocardial Infarction; Platelet Aggregation Inhibit

2000
[Apex cardiography in the hemodynamic assessment of patients with unstable stenocardia].
    Vrachebnoe delo, 1989, Issue:9

    Topics: Alanine; Angina Pectoris; Angina, Unstable; beta-Alanine; Cardiac Pacing, Artificial; Echocardiograp

1989