alanine has been researched along with Amyloidosis in 17 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oculopharyngeal muscular dystrophy is a late-onset disease caused by an elongation of a natural 10-alanine segment within the N-terminal domain of the nuclear poly(A)-binding protein 1 (PABPN1) to maximally 17 alanines." | 1.38 | Polyalanine-independent conformational conversion of nuclear poly(A)-binding protein 1 (PABPN1). ( Hause, G; Kühn, U; Schwarz, E; Winter, R, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sant'Anna, R | 1 |
| Almeida, MR | 1 |
| Varejāo, N | 1 |
| Gallego, P | 1 |
| Esperante, S | 1 |
| Ferreira, P | 1 |
| Pereira-Henriques, A | 1 |
| Palhano, FL | 1 |
| de Carvalho, M | 1 |
| Foguel, D | 1 |
| Reverter, D | 1 |
| Saraiva, MJ | 1 |
| Ventura, S | 1 |
| Morgan, GJ | 1 |
| Usher, GA | 1 |
| Kelly, JW | 1 |
| Podoly, E | 1 |
| Hanin, G | 1 |
| Soreq, H | 1 |
| Dey, BR | 1 |
| Chung, SS | 1 |
| Spitzer, TR | 1 |
| Zheng, H | 1 |
| Macgillivray, TE | 1 |
| Seldin, DC | 1 |
| McAfee, S | 1 |
| Ballen, K | 1 |
| Attar, E | 1 |
| Wang, T | 1 |
| Shin, J | 1 |
| Newton-Cheh, C | 1 |
| Moore, S | 1 |
| Sanchorawala, V | 1 |
| Skinner, M | 3 |
| Madsen, JC | 1 |
| Semigran, MJ | 1 |
| Winter, R | 1 |
| Kühn, U | 1 |
| Hause, G | 1 |
| Schwarz, E | 1 |
| Aldave, AJ | 1 |
| Gutmark, JG | 1 |
| Yellore, VS | 1 |
| Affeldt, JA | 1 |
| Meallet, MA | 1 |
| Udar, N | 1 |
| Rao, NA | 1 |
| Small, KW | 1 |
| Klintworth, GK | 1 |
| Zambarakji, HJ | 1 |
| Charteris, DG | 1 |
| Ayliffe, W | 1 |
| Luthert, PJ | 1 |
| Schon, F | 1 |
| Hawkins, PN | 1 |
| Shimizu, Y | 1 |
| Takeuchi, M | 1 |
| Matsumura, M | 1 |
| Tokuda, T | 1 |
| Iwata, M | 1 |
| Kristen, AV | 1 |
| Ehlermann, P | 1 |
| Helmke, B | 1 |
| Hund, E | 1 |
| Haberkorn, U | 1 |
| Linke, RP | 1 |
| Katus, HA | 1 |
| Winter, P | 1 |
| Altland, K | 2 |
| Dengler, TJ | 1 |
| Salvi, F | 1 |
| Salvi, G | 1 |
| Volpe, R | 1 |
| Mencucci, R | 1 |
| Plasmati, R | 1 |
| Michelucci, R | 1 |
| Gobbi, P | 1 |
| Santangelo, M | 1 |
| Ferlini, A | 1 |
| Forabosco, A | 1 |
| Théberge, R | 1 |
| Connors, L | 1 |
| Skare, J | 1 |
| Falk, RH | 1 |
| Costello, CE | 1 |
| Akar, E | 1 |
| Yalcinkaya, F | 1 |
| Akar, N | 1 |
| Baba, S | 1 |
| Takahashi, T | 1 |
| Kasama, T | 1 |
| Shirasawa, H | 1 |
| Jones, LA | 1 |
| Skare, JC | 1 |
| Cohen, AS | 1 |
| Harding, JA | 1 |
| Milunsky, A | 1 |
| Koeppen, AH | 1 |
| Wallace, MR | 2 |
| Benson, MD | 2 |
| Clerici, E | 1 |
2 reviews available for alanine and Amyloidosis
| Article | Year |
|---|---|
Alanine-to-threonine substitutions and amyloid diseases: butyrylcholinesterase as a case study.
Topics: Alanine; Amino Acid Substitution; Amyloidosis; Animals; Butyrylcholinesterase; Disease; Humans; Thre | 2010 |
Genetic amyloidosis: recent advances.
Topics: Alanine; Amyloidosis; DNA Mutational Analysis; Humans; Methionine; Polymorphism, Restriction Fragmen | 1989 |
15 other studies available for alanine and Amyloidosis
| Article | Year |
|---|---|
Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
Topics: Aged; Alanine; Amino Acid Substitution; Amyloidosis; Asymptomatic Diseases; Binding Sites; Crystallo | 2017 |
Incomplete Refolding of Antibody Light Chains to Non-Native, Protease-Sensitive Conformations Leads to Aggregation: A Mechanism of Amyloidogenesis in Patients?
Topics: Alanine; Amyloid; Amyloidosis; Circular Dichroism; Endopeptidases; Humans; Immunoglobulin Light Chai | 2017 |
Cardiac transplantation followed by dose-intensive melphalan and autologous stem-cell transplantation for light chain amyloidosis and heart failure.
Topics: Adult; Aged; Alanine; Amyloidosis; Aspartate Aminotransferases; Cardiotonic Agents; Female; Heart Fa | 2010 |
Polyalanine-independent conformational conversion of nuclear poly(A)-binding protein 1 (PABPN1).
Topics: Alanine; Amyloidosis; Escherichia coli; Humans; Muscular Dystrophy, Oculopharyngeal; Poly(A)-Binding | 2012 |
Lattice corneal dystrophy associated with the Ala546Asp and Pro551Gln missense changes in the TGFBI gene.
Topics: Adult; Alanine; Amyloid; Amyloidosis; Aspartic Acid; Cornea; Corneal Dystrophies, Hereditary; DNA Mu | 2004 |
Vitreous amyloidosis in alanine 71 transthyretin mutation.
Topics: Alanine; Amyloidosis; Eye Diseases; Female; Humans; Infant; Middle Aged; Mutation; Prealbumin; Vitre | 2005 |
A case of biopsy-proven leptomeningeal amyloidosis and intravenous Ig-responsive polyneuropathy associated with the Ala25Thr transthyretin gene mutation.
Topics: Alanine; Amino Acid Substitution; Amyloid Neuropathies; Amyloidosis; Brain; Brain Stem; Cerebellum; | 2006 |
Transthyretin valine-94-alanine, a novel variant associated with late-onset systemic amyloidosis with cardiac involvement.
Topics: Alanine; Amino Acid Substitution; Amyloidosis; Base Sequence; Cardiomyopathy, Dilated; DNA Mutationa | 2007 |
Transthyretin-related TTR hereditary amyloidosis of the vitreous body. Clinical and molecular characterization in two Italian families.
Topics: Adult; Aged; Alanine; Amyloidosis; Eye Diseases; Female; Humans; Lens Diseases; Male; Middle Aged; M | 1993 |
A new amyloidogenic transthyretin variant (Val122Ala) found in a compound heterozygous patient.
Topics: Alanine; Amyloid; Amyloidosis; Female; Heterozygote; Humans; Isoelectric Focusing; Male; Mass Spectr | 1999 |
Is the Ala138Gly alteration of MEFV gene important for amyloidosis?
Topics: Alanine; Amino Acid Substitution; Amyloidosis; Cytoskeletal Proteins; Familial Mediterranean Fever; | 2001 |
Identification of two novel amyloid A protein subsets coexisting in an individual patient of AA-amyloidosis.
Topics: Alanine; Amino Acid Sequence; Amyloid; Amyloidosis; Arthritis, Rheumatoid; Female; Humans; Middle Ag | 1992 |
Familial amyloidotic polyneuropathy: a new transthyretin position 30 mutation (alanine for valine) in a family of German descent.
Topics: Adult; Alanine; Amyloid; Amyloidosis; Base Sequence; DNA; Female; Germany; Humans; Male; Molecular S | 1992 |
Familial amyloid polyneuropathy: alanine-for-threonine substitution in the transthyretin (prealbumin) molecule.
Topics: Adult; Aged; Alanine; Amyloidosis; Blotting, Southern; DNA; Female; Humans; Isoelectric Focusing; Ma | 1990 |
Induction of amyloidosis in mice upon treatment with polypeptidyl-caseins and DNP-casein. Relation to antigenicity.
Topics: Alanine; Amyloidosis; Animals; Antigens; Caseins; Female; Hemagglutination Tests; Male; Mice; Nitrob | 1972 |