Page last updated: 2024-11-08

alanine and Allergic Encephalomyelitis

alanine has been researched along with Allergic Encephalomyelitis in 11 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"Experimental allergic encephalomyelitis (EAE) is induced in susceptible animals by immunodominant determinants of myelin basic protein (MBP), such as guinea pig sequence MBP72-85."7.70Design and synthesis of a potent cyclic analogue of the myelin basic protein epitope MBP72-85: importance of the Ala81 carboxyl group and of a cyclic conformation for induction of experimental allergic encephalomyelitis. ( Daliani, I; Gerothanassis, IP; Matsoukas, E; Matsoukas, JM; Mavromoustakos, T; Moore, GJ; Probert, L; Troganis, A; Tselios, T, 1999)
"Flecainide was also potent in suppressing microglial activation in experimental autoimmune encephalomyelitis."5.39Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis. ( Bechtold, D; Chauhdry, S; Hassoon, P; Lee, W; Malpass, K; Morsali, D; Palchaudhuri, U; Piers, T; Pocock, J; Roach, A; Smith, KJ; Snell, DM, 2013)
"Experimental allergic encephalomyelitis (EAE) is induced in susceptible animals by immunodominant determinants of myelin basic protein (MBP), such as guinea pig sequence MBP72-85."3.70Design and synthesis of a potent cyclic analogue of the myelin basic protein epitope MBP72-85: importance of the Ala81 carboxyl group and of a cyclic conformation for induction of experimental allergic encephalomyelitis. ( Daliani, I; Gerothanassis, IP; Matsoukas, E; Matsoukas, JM; Mavromoustakos, T; Moore, GJ; Probert, L; Troganis, A; Tselios, T, 1999)
"Flecainide was also potent in suppressing microglial activation in experimental autoimmune encephalomyelitis."1.39Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis. ( Bechtold, D; Chauhdry, S; Hassoon, P; Lee, W; Malpass, K; Morsali, D; Palchaudhuri, U; Piers, T; Pocock, J; Roach, A; Smith, KJ; Snell, DM, 2013)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's2 (18.18)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morsali, D1
Bechtold, D1
Lee, W1
Chauhdry, S1
Palchaudhuri, U1
Hassoon, P1
Snell, DM1
Malpass, K1
Piers, T1
Pocock, J1
Roach, A1
Smith, KJ1
Zhou, Q1
Rammohan, K1
Lin, S1
Robinson, N1
Li, O1
Liu, X1
Bai, XF1
Yin, L1
Scarberry, B1
Du, P1
You, M1
Guan, K1
Zheng, P1
Liu, Y1
Mangalam, AK1
Khare, M1
Krco, CJ1
Rodriguez, M1
David, CS1
Tselios, T1
Probert, L1
Daliani, I1
Matsoukas, E1
Troganis, A1
Gerothanassis, IP1
Mavromoustakos, T1
Moore, GJ1
Matsoukas, JM1
Khanarian, G1
Margetson, SA1
Moore, WJ1
Pasaribu, SJ1
Westall, FC1
Wauben, MH1
Boog, CJ1
van der Zee, R1
Joosten, I1
Schlief, A1
van Eden, W1
Teitelbaum, D4
Webb, C3
Meshorer, A4
Arnon, R4
Sela, M4
Diessner, H1
Schmidt, RM1
Bree, M1
Hirshfeld, T1

Other Studies

11 other studies available for alanine and Allergic Encephalomyelitis

ArticleYear
Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis.
    Brain : a journal of neurology, 2013, Volume: 136, Issue:Pt 4

    Topics: Alanine; Animals; Benzylamines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental;

2013
CD24 is a genetic modifier for risk and progression of multiple sclerosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Dec-09, Volume: 100, Issue:25

    Topics: Alanine; Alleles; Animals; Antigens, CD; CD24 Antigen; CD3 Complex; Cell Membrane; Cloning, Molecula

2003
Delineation of the minimal encephalitogenic epitope of proteolipid protein peptide(91-110) and critical residues required for induction of EAE in HLA-DR3 transgenic mice.
    Journal of neuroimmunology, 2005, Volume: 161, Issue:1-2

    Topics: Alanine; Animals; Apoproteins; Brain; Cell Proliferation; Cytokines; Disease Models, Animal; Dose-Re

2005
Design and synthesis of a potent cyclic analogue of the myelin basic protein epitope MBP72-85: importance of the Ala81 carboxyl group and of a cyclic conformation for induction of experimental allergic encephalomyelitis.
    Journal of medicinal chemistry, 1999, Apr-08, Volume: 42, Issue:7

    Topics: Alanine; Animals; Chromatography, High Pressure Liquid; Drug Design; Encephalomyelitis, Autoimmune,

1999
Effect of substitution of D-alanine for L-alanine on activity and conformation of an encephalitogenic peptide.
    Biochemical and biophysical research communications, 1979, Mar-15, Volume: 87, Issue:1

    Topics: Alanine; Animals; Biological Assay; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Models

1979
Disease inhibition by major histocompatibility complex binding peptide analogues of disease-associated epitopes: more than blocking alone.
    The Journal of experimental medicine, 1992, Sep-01, Volume: 176, Issue:3

    Topics: Alanine; Amino Acid Sequence; Animals; Arthritis, Experimental; Binding, Competitive; Cell Division;

1992
Protection against experimental allergic encephalomyelitis.
    Nature, 1972, Dec-29, Volume: 240, Issue:5383

    Topics: Alanine; Amino Acids; Animals; Cross Reactions; Encephalomyelitis, Autoimmune, Experimental; Freund'

1972
[Biochemical studies on experimental allergic encephalomyelitis under treatment with antilymphocyte serum].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1972, Volume: 24, Issue:11

    Topics: Alanine; Animals; Antibodies; Antibody Formation; Antilymphocyte Serum; Brain; Encephalomyelitis, Au

1972
Suppression by several synthetic polypeptides of experimental allergic encephalomyelitis induced in guinea pigs and rabbits with bovine and human basic encephalitogen.
    European journal of immunology, 1973, Volume: 3, Issue:5

    Topics: Alanine; Amino Acids; Animals; Antibodies; Aspartic Acid; Brain; Coliphages; Dinitrophenols; Encepha

1973
Suppression of experimental allergic encephalomyelitis in Rhesus monkeys by a synthetic basic copolymer.
    Clinical immunology and immunopathology, 1974, Volume: 3, Issue:2

    Topics: Alanine; Animals; Brain; Cerebellum; Encephalomyelitis, Autoimmune, Experimental; Female; Freund's A

1974
Suppression of experimental allergic encephalomyelitis by a synthetic polypeptide.
    European journal of immunology, 1971, Volume: 1, Issue:4

    Topics: Alanine; Animals; Autoanalysis; Brain; Cytochromes; Encephalomyelitis, Autoimmune, Experimental; Glu

1971