alanine has been researched along with Akinetic-Rigid Variant of Huntington Disease in 10 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We found that S421 phosphorylation mitigates neurodegeneration by increasing proteasome-dependent turnover of mHTT and reducing the presence of a toxic mHTT conformer." | 1.43 | Serine 421 regulates mutant huntingtin toxicity and clearance in mice. ( Daub, AC; Finkbeiner, S; Gu, X; Humbert, S; Kratter, IH; Lau, A; Masliah, E; Osmand, A; Saudou, F; Steffan, JS; Tsvetkov, AS; Weiberth, KF; Yang, XW; Zahed, H, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kratter, IH | 1 |
| Zahed, H | 1 |
| Lau, A | 1 |
| Tsvetkov, AS | 1 |
| Daub, AC | 1 |
| Weiberth, KF | 1 |
| Gu, X | 2 |
| Saudou, F | 1 |
| Humbert, S | 1 |
| Yang, XW | 2 |
| Osmand, A | 2 |
| Steffan, JS | 2 |
| Masliah, E | 1 |
| Finkbeiner, S | 2 |
| Greiner, ER | 1 |
| Mishra, R | 1 |
| Kodali, R | 1 |
| Thompson, LM | 1 |
| Wetzel, R | 1 |
| Squitieri, F | 1 |
| Cannella, M | 1 |
| Simonelli, M | 1 |
| COWIE, V | 1 |
| SEAKINS, JW | 1 |
| Reilmann, R | 1 |
| Rolf, LH | 1 |
| Lange, HW | 1 |
| Harris, CA | 1 |
| Miranda, AF | 1 |
| Tanguay, JJ | 1 |
| Boegman, RJ | 1 |
| Beninger, RJ | 1 |
| Jhamandas, K | 1 |
| Holbert, S | 1 |
| Denghien, I | 1 |
| Kiechle, T | 1 |
| Rosenblatt, A | 1 |
| Wellington, C | 1 |
| Hayden, MR | 1 |
| Margolis, RL | 1 |
| Ross, CA | 1 |
| Dausset, J | 1 |
| Ferrante, RJ | 1 |
| Néri, C | 1 |
| Perry, TL | 2 |
| Diamond, S | 1 |
| Hansen, S | 2 |
| Stedman, D | 1 |
| Insarova, NG | 1 |
| Lesk, D | 1 |
10 other studies available for alanine and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Serine 421 regulates mutant huntingtin toxicity and clearance in mice.
Topics: Alanine; Animals; Aspartic Acid; Behavior, Animal; Chromosomes, Artificial, Bacterial; Disease Model | 2016 |
Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amyloid; Animals; Aspartic Acid; Disease Mode | 2009 |
CAG mutation effect on rate of progression in Huntington's disease.
Topics: Age of Onset; Alanine; Cysteine; Disease Progression; DNA Mutational Analysis; Female; Follow-Up Stu | 2002 |
Urinary alanine excretor in a Huntington's chorea family.
Topics: Alanine; Body Fluids; Chorea; Humans; Huntington Disease | 1962 |
Decreased plasma alanine and isoleucine in Huntington's disease.
Topics: Adult; Alanine; Female; Humans; Huntington Disease; Isoleucine; Male; Middle Aged; Plasma | 1995 |
Modulation of striatal quinolinate neurotoxicity by elevation of endogenous brain kynurenic acid.
Topics: Alanine; Animals; Anticonvulsants; Corpus Striatum; Dose-Response Relationship, Drug; Drug Synergism | 1998 |
The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesis.
Topics: Age of Onset; Alanine; Animals; Brain; Caenorhabditis elegans; Dinucleotide Repeats; Glutamine; Helm | 2001 |
Plasma-aminoacid levels in Huntington's chorea.
Topics: Adult; Alanine; Amino Acids; Female; Humans; Huntington Disease; Isoleucine; Leucine; Male; Middle A | 1969 |
[Urinary excretion of free amino acids in families of patints with Huntington's chorea].
Topics: Adult; Aged; Alanine; Amino Acids; Chromatography, Paper; Female; Glutamates; Humans; Huntington Dis | 1969 |
[Plasma amino acid levels in children of patients with Huntington's chorea].
Topics: Adolescent; Adult; Alanine; Amino Acids; Child; Child, Preschool; Female; Humans; Huntington Disease | 1972 |