alanine has been researched along with Acute-On-Chronic Liver Failure (ACLF) in 3 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tenofovir alafenamide (TAF) has been available in China for a short time, little is known about its safety and efficacy in patients with hepatitis B virus (HBV)-related acute-on-chronic liver failure (HBV-ACLF)." | 8.02 | The 48-week safety and therapeutic effects of tenofovir alafenamide in hbv-related acute-on-chronic liver failure: A prospective cohort study. ( Lai, J; Li, J; Li, X; Peng, L; Shu, X; Xie, C; Xie, J; Xu, W; Zhang, Y; Zhu, X, 2021) |
| " The treatment using NAs was well-tolerated and there was no serious drug-related adverse event reported." | 7.01 | Short-term and long-term safety and efficacy of tenofovir alafenamide, tenofovir disoproxil fumarate and entecavir treatment of acute-on-chronic liver failure associated with hepatitis B. ( Chen, T; Chen, Y; Fu, M; Fu, S; Gao, Z; He, Y; Hu, C; Li, J; Liu, J; Yan, T; Yang, Y; Zhang, R; Zhao, Y; Zhou, M, 2021) |
| "Tenofovir alafenamide (TAF) has been available in China for a short time, little is known about its safety and efficacy in patients with hepatitis B virus (HBV)-related acute-on-chronic liver failure (HBV-ACLF)." | 4.02 | The 48-week safety and therapeutic effects of tenofovir alafenamide in hbv-related acute-on-chronic liver failure: A prospective cohort study. ( Lai, J; Li, J; Li, X; Peng, L; Shu, X; Xie, C; Xie, J; Xu, W; Zhang, Y; Zhu, X, 2021) |
| " The treatment using NAs was well-tolerated and there was no serious drug-related adverse event reported." | 3.01 | Short-term and long-term safety and efficacy of tenofovir alafenamide, tenofovir disoproxil fumarate and entecavir treatment of acute-on-chronic liver failure associated with hepatitis B. ( Chen, T; Chen, Y; Fu, M; Fu, S; Gao, Z; He, Y; Hu, C; Li, J; Liu, J; Yan, T; Yang, Y; Zhang, R; Zhao, Y; Zhou, M, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Y | 1 |
| Xu, W | 1 |
| Zhu, X | 1 |
| Li, X | 1 |
| Li, J | 3 |
| Shu, X | 1 |
| Lai, J | 1 |
| Xie, J | 1 |
| Xie, C | 1 |
| Peng, L | 1 |
| Hu, C | 1 |
| Chen, Y | 1 |
| Zhang, R | 1 |
| Fu, S | 1 |
| Zhou, M | 1 |
| Gao, Z | 1 |
| Fu, M | 1 |
| Yan, T | 1 |
| Yang, Y | 1 |
| Liu, J | 1 |
| Chen, T | 1 |
| Zhao, Y | 1 |
| He, Y | 1 |
| Faitot, F | 1 |
| Ruhland, E | 1 |
| Oncioiu, C | 1 |
| Besch, C | 1 |
| Addeo, P | 1 |
| Cicek, AE | 1 |
| Bachellier, P | 1 |
| Namer, IJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter Controlled Open-label Trial of Evaluating Tenofovir Alafenamide, Tenofovir Disoproxil Fumarate and Entecavir in Acute-on-chronic Liver Failure of Chronic Hepatitis B Patients[NCT03640728] | 200 participants (Anticipated) | Observational | 2019-01-25 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for alanine and Acute-On-Chronic Liver Failure (ACLF)
| Article | Year |
|---|---|
Short-term and long-term safety and efficacy of tenofovir alafenamide, tenofovir disoproxil fumarate and entecavir treatment of acute-on-chronic liver failure associated with hepatitis B.
Topics: Acute-On-Chronic Liver Failure; Adenine; Adult; Alanine; Antiviral Agents; Guanine; Hepatitis B viru | 2021 |
2 other studies available for alanine and Acute-On-Chronic Liver Failure (ACLF)
| Article | Year |
|---|---|
The 48-week safety and therapeutic effects of tenofovir alafenamide in hbv-related acute-on-chronic liver failure: A prospective cohort study.
Topics: Acute-On-Chronic Liver Failure; Alanine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, | 2021 |
Metabolomic profiling highlights the metabolic bases of acute-on-chronic and post-hepatectomy liver failure.
Topics: Acute-On-Chronic Liver Failure; Aged; Alanine; Biomarkers; Carcinoma, Hepatocellular; Female; Follow | 2019 |