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alanine and Acute Kidney Injury

alanine has been researched along with Acute Kidney Injury in 26 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"We describe a patient with two recent episodes of tenofovir disoproxil fumarate (TDF)-associated acute kidney injury and six-class drug-resistant HIV infection who achieved and maintained viral suppression without worsening kidney function on a regimen including tenofovir alafenamide (TAF) through 48 weeks of therapy."3.83Tenofovir alafenamide as part of a salvage regimen in a patient with multi-drug resistant HIV and tenofovir-DF-associated renal tubulopathy. ( Dewar, RL; Kopp, JB; Lane, HC; Maldarelli, F; Manion, MM; Mikula, JM; Norman-Wheeler, JF; Ober, AG; Pau, AK; Suarez, LM, 2016)
" Glomerular damage caused by puromycin aminonucleoside did not induce aminoaciduria until marked proteinuria occurred (day 9), and even then amino acid excretion was much less than that caused by gentamicin."3.68Aminoaciduria is an earlier index of renal tubular damage than conventional renal disease markers in the gentamicin-rat model of acute renal failure. ( Goldberg, DM; Macpherson, NA; Moscarello, MA, 1991)
"The current management of acute renal failure rests largely on the avoidance of ischemic and nephrotoxic insults, attention to fluid and electrolyte balance, and the use of dialytic procedures when necessary."2.39Therapeutic strategies in the prevention of acute renal failure. ( Fischereder, M; Nath, KA; Trick, W, 1994)
"HBsAg-positive cancer patients treated with ETV (n = 582), TDF (n = 200) and TAF (n = 188) during chemotherapy were retrospectively enrolled."1.72Efficacy and Renal Safety of Prophylactic Tenofovir Alafenamide for HBV-Infected Cancer Patients Undergoing Chemotherapy. ( Chao, Y; Hou, MC; Huang, YH; Lan, KH; Lee, IC; Li, CP; Lin, HC; Su, CW, 2022)
"The combination of the terms "acute renal failure" and "remdesivir" yielded a statistically significant disproportionality signal with 138 observed cases instead of the 9 expected."1.62Remdesivir and Acute Renal Failure: A Potential Safety Signal From Disproportionality Analysis of the WHO Safety Database. ( Drici, MD; Esnault, VLM; Fresse, A; Gérard, AO; Laurain, A; Muzzone, M; Parassol, N; Rocher, F, 2021)
"Acquired Fanconi syndrome has been associated with the long-term ingestion of several nucleoside analogs used to treat chronic hepatitis B virus infection."1.51A case of entecavir-induced Fanconi syndrome. ( Fujii, T; Kawasoe, K; Nitta, K; Ohta, A, 2019)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19905 (19.23)18.7374
1990's5 (19.23)18.2507
2000's0 (0.00)29.6817
2010's4 (15.38)24.3611
2020's12 (46.15)2.80

Authors

AuthorsStudies
Wang, S1
Huynh, C1
Islam, S1
Malone, B1
Masani, N1
Joseph, D1
Wong, CKH1
Au, ICH1
Cheng, WY1
Man, KKC1
Lau, KTK1
Mak, LY1
Lui, SL1
Chung, MSH1
Xiong, X1
Lau, EHY1
Cowling, BJ1
Lee, IC1
Lan, KH1
Su, CW1
Li, CP1
Chao, Y1
Lin, HC1
Hou, MC1
Huang, YH1
Sise, ME2
Baggett, MV1
Shepard, JO1
Stevens, JS1
Rhee, EP2
Antinori, S1
Cossu, MV1
Ridolfo, AL1
Rech, R1
Bonazzetti, C1
Pagani, G1
Gubertini, G1
Coen, M1
Magni, C1
Castelli, A1
Borghi, B1
Colombo, R1
Giorgi, R1
Angeli, E1
Mileto, D1
Milazzo, L1
Vimercati, S1
Pellicciotta, M1
Corbellino, M1
Torre, A1
Rusconi, S1
Oreni, L1
Gismondo, MR1
Giacomelli, A1
Meroni, L1
Rizzardini, G1
Galli, M1
Morales, A1
Danziger, J1
Adamsick, ML1
Gandhi, RG1
Bidell, MR1
Elshaboury, RH1
Bhattacharyya, RP1
Kim, AY1
Nigwekar, S1
Bruchfeld, A1
Gérard, AO1
Laurain, A1
Fresse, A1
Parassol, N1
Muzzone, M1
Rocher, F1
Esnault, VLM1
Drici, MD1
Ozsurekci, Y1
Oygar, PD1
Gürlevik, SL1
Kesici, S1
Ozen, S1
Kurt Sukur, ED1
Gülhan, B1
Topaloglu, R1
Bayrakci, B1
Cengiz, AB1
Yin, L1
Zhao, H1
Zhang, H1
Li, Y1
Dong, Y1
Ju, H1
Kong, F1
Zhao, S1
Singh, A1
Kamath, A1
Fujii, T1
Kawasoe, K1
Ohta, A1
Nitta, K1
Rodionov, RN1
Martens-Lobenhoffer, J1
Brilloff, S1
Hohenstein, B1
Jarzebska, N1
Jabs, N1
Kittel, A1
Maas, R1
Weiss, N1
Bode-Böger, SM1
Mikula, JM1
Manion, MM1
Maldarelli, F1
Suarez, LM1
Norman-Wheeler, JF1
Ober, AG1
Dewar, RL1
Kopp, JB1
Lane, HC1
Pau, AK1
Nielsen, PM1
Laustsen, C1
Bertelsen, LB1
Qi, H1
Mikkelsen, E1
Kristensen, ML1
Nørregaard, R1
Stødkilde-Jørgensen, H1
Zager, RA1
Johannes, G1
Tuttle, SE1
Sharma, HM1
Kaltenbach, JP1
Carone, FA1
Ganote, CE1
Fischereder, M1
Trick, W1
Nath, KA1
Masuda, T1
Suzuki, A1
Obana, M1
Matsuoka, Y1
Irimajiri, S1
Kinosaki, M1
Yamaguchi, K1
Yamashita, Y1
Uematsu, Y1
Aihara, H1
Masunaga, H1
Morinaga, T1
Higashio, K1
Assan, R1
Heuclin, C1
Ganeval, D1
Bismuth, C1
George, J1
Girard, JR1
Kirschbaum, BB1
Chesney, RW1
Kaplan, BS1
Freedom, RM1
Haller, JA1
Drummond, KN1
Macpherson, NA1
Moscarello, MA1
Goldberg, DM1
Weinberg, JM1

Reviews

4 reviews available for alanine and Acute Kidney Injury

ArticleYear
Remdesivir in Patients with Acute or Chronic Kidney Disease and COVID-19.
    Journal of the American Society of Nephrology : JASN, 2020, Volume: 31, Issue:7

    Topics: Acute Kidney Injury; Adenosine Monophosphate; Alanine; Antiviral Agents; Cause of Death; Comorbidity

2020
The COVID-19 pandemic: consequences for nephrology.
    Nature reviews. Nephrology, 2021, Volume: 17, Issue:2

    Topics: Acute Kidney Injury; Adenosine Monophosphate; Alanine; Antiviral Agents; COVID-19; COVID-19 Drug Tre

2021
Therapeutic strategies in the prevention of acute renal failure.
    Seminars in nephrology, 1994, Volume: 14, Issue:1

    Topics: Acute Kidney Injury; Adenosine Triphosphate; Alanine; Animals; Atrial Natriuretic Factor; Calcium Ch

1994
The effect of amino acids on ischemic and toxic injury to the kidney.
    Seminars in nephrology, 1990, Volume: 10, Issue:5

    Topics: Acute Kidney Injury; Alanine; Amino Acids; Animals; Glutathione; Glycine; Humans; Ischemia; Kidney

1990

Trials

2 trials available for alanine and Acute Kidney Injury

ArticleYear
Compassionate remdesivir treatment of severe Covid-19 pneumonia in intensive care unit (ICU) and Non-ICU patients: Clinical outcome and differences in post-treatment hospitalisation status.
    Pharmacological research, 2020, Volume: 158

    Topics: Acute Kidney Injury; Adenosine Monophosphate; Aged; Alanine; Antiviral Agents; Betacoronavirus; Comp

2020
Favipiravir use in children with COVID-19 and acute kidney injury: is it safe?
    Pediatric nephrology (Berlin, Germany), 2021, Volume: 36, Issue:11

    Topics: Acute Kidney Injury; Adenosine Monophosphate; Adolescent; Alanine; Amides; Child; COVID-19; COVID-19

2021

Other Studies

20 other studies available for alanine and Acute Kidney Injury

ArticleYear
Assessment of Safety of Remdesivir in Covid - 19 Patients with Estimated Glomerular Filtration Rate (eGFR) < 30 ml/min per 1.73 m^2.
    Journal of intensive care medicine, 2022, Volume: 37, Issue:6

    Topics: Acute Kidney Injury; Adenosine Monophosphate; Adult; Alanine; COVID-19 Drug Treatment; Creatinine; F

2022
Remdesivir use and risks of acute kidney injury and acute liver injury among patients hospitalised with COVID-19: a self-controlled case series study.
    Alimentary pharmacology & therapeutics, 2022, Volume: 56, Issue:1

    Topics: Acute Kidney Injury; Adenosine Monophosphate; Alanine; COVID-19 Drug Treatment; Hong Kong; Humans; L

2022
Efficacy and Renal Safety of Prophylactic Tenofovir Alafenamide for HBV-Infected Cancer Patients Undergoing Chemotherapy.
    International journal of molecular sciences, 2022, Sep-26, Volume: 23, Issue:19

    Topics: Acute Kidney Injury; Adenine; Alanine; Antiviral Agents; Cisplatin; Hepatitis B Surface Antigens; He

2022
Case 17-2020: A 68-Year-Old Man with Covid-19 and Acute Kidney Injury.
    The New England journal of medicine, 2020, May-28, Volume: 382, Issue:22

    Topics: Acute Kidney Injury; Adenosine Monophosphate; Aged; Alanine; Amides; Anti-Inflammatory Agents; Antic

2020
Management Consideration in Drug-Induced Lactic Acidosis.
    Clinical journal of the American Society of Nephrology : CJASN, 2020, 10-07, Volume: 15, Issue:10

    Topics: Acidosis, Lactic; Acute Kidney Injury; Aged; Alanine; Continuous Renal Replacement Therapy; Diabetes

2020
Remdesivir and Acute Renal Failure: A Potential Safety Signal From Disproportionality Analysis of the WHO Safety Database.
    Clinical pharmacology and therapeutics, 2021, Volume: 109, Issue:4

    Topics: Acute Kidney Injury; Adenosine Monophosphate; Alanine; Antiviral Agents; COVID-19 Drug Treatment; Hu

2021
Remdesivir Alleviates Acute Kidney Injury by Inhibiting the Activation of NLRP3 Inflammasome.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Acute Kidney Injury; Adenosine Monophosphate; Alanine; Animals; Anti-Inflammatory Agents; Cells, Cul

2021
Assessment of adverse events associated with remdesivir use for coronavirus disease 2019 using real-world data.
    Expert opinion on drug safety, 2021, Volume: 20, Issue:12

    Topics: Acute Kidney Injury; Adenosine Monophosphate; Adverse Drug Reaction Reporting Systems; Alanine; Anti

2021
A case of entecavir-induced Fanconi syndrome.
    CEN case reports, 2019, Volume: 8, Issue:4

    Topics: Acidosis; Acute Kidney Injury; Adenine; Aged; Alanine; Antiviral Agents; Fanconi Syndrome; Guanine;

2019
Role of alanine:glyoxylate aminotransferase 2 in metabolism of asymmetric dimethylarginine in the settings of asymmetric dimethylarginine overload and bilateral nephrectomy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2014, Volume: 29, Issue:11

    Topics: Acute Kidney Injury; Alanine; Animals; Arginine; Biomarkers; Blotting, Western; Disease Models, Anim

2014
Tenofovir alafenamide as part of a salvage regimen in a patient with multi-drug resistant HIV and tenofovir-DF-associated renal tubulopathy.
    Antiviral therapy, 2016, Volume: 21, Issue:6

    Topics: Acute Kidney Injury; Adenine; Alanine; Anti-HIV Agents; Drug Resistance, Multiple, Viral; HIV Infect

2016
In situ lactate dehydrogenase activity: a novel renal cortical imaging biomarker of tubular injury?
    American journal of physiology. Renal physiology, 2017, 03-01, Volume: 312, Issue:3

    Topics: Acute Kidney Injury; Alanine; Animals; Bicarbonates; Biomarkers; Carbon Isotopes; Disease Models, An

2017
Acute amino acid nephrotoxicity.
    The Journal of laboratory and clinical medicine, 1983, Volume: 101, Issue:1

    Topics: Acute Kidney Injury; Alanine; Albuminuria; Amino Acids; Animals; Arginine; Aspartic Acid; Female; Gl

1983
Compounds protective against renal tubular necrosis induced by D-serine and D-2,3-diaminopropionic acid in the rat.
    Experimental and molecular pathology, 1982, Volume: 37, Issue:2

    Topics: Acute Kidney Injury; Alanine; Amino Acids; Animals; beta-Alanine; Kidney Tubular Necrosis, Acute; Ra

1982
[A case of infective endocarditis with purpura and macroscopic hematuria as initial manifestations].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1996, Volume: 70, Issue:4

    Topics: Acute Kidney Injury; Adult; Alanine; Endocarditis, Bacterial; Female; Hematuria; Humans; IgA Vasculi

1996
A mutant of deleted variant of hepatocyte growth factor (dHGF) with alanine substitution in the N-terminal basic region has higher activity in vivo.
    Biochemical and biophysical research communications, 1999, Jan-19, Volume: 254, Issue:2

    Topics: Acute Kidney Injury; Alanine; Amino Acid Substitution; Animals; Blood Proteins; Cell Division; Cell

1999
Metformin-induced lactic acidosis in the presence of acute renal failure.
    Diabetologia, 1977, Volume: 13, Issue:3

    Topics: Acute Kidney Injury; Adult; Aged; Alanine; Blood Glucose; Creatinine; Diabetic Ketoacidosis; Female;

1977
Alanine aminopeptidase excretion after mercuric chloride renal failure.
    Biochemical medicine, 1979, Volume: 21, Issue:2

    Topics: Acute Kidney Injury; Alanine; Aminopeptidases; Animals; Clinical Enzyme Tests; Creatinine; Female; M

1979
Acute renal failure: an important complication of cardiac surgery in infants.
    The Journal of pediatrics, 1975, Volume: 87, Issue:3

    Topics: Acute Kidney Injury; Alanine; Cardiac Surgical Procedures; Female; Heart Defects, Congenital; Humans

1975
Aminoaciduria is an earlier index of renal tubular damage than conventional renal disease markers in the gentamicin-rat model of acute renal failure.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1991, Volume: 14, Issue:2

    Topics: Acetylglucosaminidase; Acute Kidney Injury; Alanine; Amino Acids; Animals; Biomarkers; Creatinine; G

1991