alamethicin and Skin-Neoplasms

alamethicin has been researched along with Skin-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for alamethicin and Skin-Neoplasms

Article	Year
Photosensitizing effect of protoporphyrin IX in pigmented melanoma of mice. Biochemical and biophysical research communications, 2002, Sep-27, Volume: 297, Issue:3 No fluorescence of protoporphyrin IX (PpIX) was measured using a fiber optic probe in pigmented B16F10 melanoma in mice after topical application of 5-aminolevulinic acid methylester (ALA-Me). However, chemical extraction of tissues excised from mice after intratumoral administration of ALA-Me or its parent compound ALA revealed that this tumor had the capability to produce PpIX. Small amounts of endogenous porphyrins, mainly PpIX, were found in the melanoma not treated with these drugs. Topical application of ALA-Me followed by exposure with laser light (633nm) delayed the growth of the tumors slightly. Light alone also had a significant effect on the tumor growth. Topics: Administration, Topical; Alamethicin; Aminolevulinic Acid; Animals; Cell Division; Hutchinson's Melanotic Freckle; Melanoma, Experimental; Mice; Photosensitizing Agents; Protoporphyrins; Skin Neoplasms; Spectrometry, Fluorescence; Tumor Cells, Cultured	2002

Article

Year

Photosensitizing effect of protoporphyrin IX in pigmented melanoma of mice.

Biochemical and biophysical research communications, 2002, Sep-27, Volume: 297, Issue:3

No fluorescence of protoporphyrin IX (PpIX) was measured using a fiber optic probe in pigmented B16F10 melanoma in mice after topical application of 5-aminolevulinic acid methylester (ALA-Me). However, chemical extraction of tissues excised from mice after intratumoral administration of ALA-Me or its parent compound ALA revealed that this tumor had the capability to produce PpIX. Small amounts of endogenous porphyrins, mainly PpIX, were found in the melanoma not treated with these drugs. Topical application of ALA-Me followed by exposure with laser light (633nm) delayed the growth of the tumors slightly. Light alone also had a significant effect on the tumor growth.

Topics: Administration, Topical; Alamethicin; Aminolevulinic Acid; Animals; Cell Division; Hutchinson's Melanotic Freckle; Melanoma, Experimental; Mice; Photosensitizing Agents; Protoporphyrins; Skin Neoplasms; Spectrometry, Fluorescence; Tumor Cells, Cultured

2002