Page last updated: 2024-09-05

alagebrium and Diabetic Glomerulosclerosis

alagebrium has been researched along with Diabetic Glomerulosclerosis in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (83.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrikopoulos, S; Bierhaus, A; Cooper, ME; Coughlan, MT; Forbes, JM; Harcourt, BE; O'Brien, RC; Penfold, S; Sourris, KC; Tan, AL; Thallas-Bonke, V; Thomas, MC1
Choi, WJ; Ha, H; Huh, JY; Jeong, LS; Kim, J; Kim, WY; Kwon, MK; Lee, GT; Lee, HB; Nagai, R; Park, J1
Kawakami, M; Kuroki, M1
Burns, WC; Cooper, ME; Forbes, JM; Founds, HW; Jerums, G; Thallas, V; Thomas, MC1
Cooper, M; Forbes, J; Jerums, G; Osicka, T; Panagiotopoulos, S1
Allen, TJ; Burns, WC; Calkin, AC; Candido, R; Cooper, ME; Forbes, JM; Jandeleit-Dahm, KA; Lassila, M; Seah, KK; Thallas, V; Thomas, MC1
Bach, LA; Boner, G; Cooper, ME; Forbes, JM; Haller, H; Lindschau, C; Meier, M; Rizkalla, B; Thallas-Bonke, V1
Cooper, ME1
Tuttle, KR; Williams, ME1
Allen, TJ; Jandeleit-Dahm, KA; Lassila, M1
Basgen, J; Brem, H; Cai, W; Li, Z; Peppa, M; Uribarri, J; Vlassara, H; Zhang, JG1
Cooper, ME; Coughlan, MT; Forbes, JM1

Reviews

6 review(s) available for alagebrium and Diabetic Glomerulosclerosis

ArticleYear
[Aminoguanidine and other AGE inhibitors].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 9

    Topics: Amides; Animals; Arteriosclerosis; Cardiovascular Diseases; Cataract; Clinical Trials as Topic; Diabetes Mellitus; Diabetic Nephropathies; Diabetic Retinopathy; Disease Models, Animal; Drug Design; Glycation End Products, Advanced; Guanidines; Humans; Hydrazines; Hypoglycemic Agents; Thiadiazoles; Thiazoles; Thiazolidines

2002
Evolving concepts in advanced glycation, diabetic nephropathy, and diabetic vascular disease.
    Archives of biochemistry and biophysics, 2003, Nov-01, Volume: 419, Issue:1

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Enzyme Inhibitors; Forecasting; Glycation End Products, Advanced; Guanidines; Humans; Protein Kinase C; Ramipril; Renin-Angiotensin System; Thiazoles

2003
Importance of advanced glycation end products in diabetes-associated cardiovascular and renal disease.
    American journal of hypertension, 2004, Volume: 17, Issue:12 Pt 2

    Topics: Animals; Atherosclerosis; Blood Glucose; Cardiomyopathies; Cardiovascular Agents; Diabetic Angiopathies; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Humans; Myocardium; Thiazoles

2004
The next generation of diabetic nephropathy therapies: an update.
    Advances in chronic kidney disease, 2005, Volume: 12, Issue:2

    Topics: Animals; Diabetic Nephropathies; Disease Progression; Enzyme Inhibitors; Glycation End Products, Advanced; Glycosaminoglycans; Humans; Indoles; Maleimides; Models, Animal; Protein Kinase C; Pyridoxamine; Renal Agents; Thiazoles

2005
Advanced glycation end products in diabetes-associated atherosclerosis and renal disease: interventional studies.
    Annals of the New York Academy of Sciences, 2005, Volume: 1043

    Topics: Amides; Animals; Arteriosclerosis; Diabetic Angiopathies; Diabetic Nephropathies; Glycation End Products, Advanced; Humans; Hydrazines; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Thiazoles

2005
Role of the AGE crosslink breaker, alagebrium, as a renoprotective agent in diabetes.
    Kidney international. Supplement, 2007, Issue:106

    Topics: Angiotensin-Converting Enzyme Inhibitors; Diabetic Nephropathies; Glycation End Products, Advanced; Humans; Isoenzymes; Protein Kinase C; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renin-Angiotensin System; Thiazoles

2007

Other Studies

6 other study(ies) available for alagebrium and Diabetic Glomerulosclerosis

ArticleYear
Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy.
    American journal of physiology. Renal physiology, 2010, Volume: 298, Issue:3

    Topics: Adenosine Triphosphate; Albuminuria; Animals; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet; Disease Models, Animal; Disease Progression; Glycation End Products, Advanced; Glycolysis; Ion Channels; Kidney; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitochondrial Proteins; Oxidative Stress; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Superoxides; Thiazoles; Time Factors; Uncoupling Protein 2

2010
Renoprotective antioxidant effect of alagebrium in experimental diabetes.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:11

    Topics: Acute Kidney Injury; Albuminuria; Animals; Antioxidants; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hydrogen Peroxide; Immunoenzyme Techniques; Male; Mesangial Cells; Mice; Mice, Inbred C57BL; NADPH Oxidases; Oxidative Stress; Protein Kinase C; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger; Thiazoles

2011
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:12

    Topics: Albuminuria; Animal Population Groups; Animals; Blood Pressure; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kinetics; Lysine; Models, Biological; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine

2003
Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: role of advanced glycation end products.
    Journal of the American Society of Nephrology : JASN, 2004, Volume: 15, Issue:8

    Topics: Actins; Animals; Apolipoproteins E; Blood Pressure; Body Weight; Collagen Type I; Collagen Type IV; Diabetic Nephropathies; Glycation End Products, Advanced; Kidney; Lipid Metabolism; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1

2004
Attenuation of extracellular matrix accumulation in diabetic nephropathy by the advanced glycation end product cross-link breaker ALT-711 via a protein kinase C-alpha-dependent pathway.
    Diabetes, 2004, Volume: 53, Issue:11

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Extracellular Matrix Proteins; Glycation End Products, Advanced; Guanidines; Kidney Cortex; Male; Protein Kinase C; Protein Kinase C-alpha; Protein Transport; Rats; Rats, Sprague-Dawley; Thiazoles

2004
Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711).
    American journal of nephrology, 2006, Volume: 26, Issue:5

    Topics: Animals; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Lysine; Mice; Mice, Mutant Strains; Thiazoles

2006