ailanthoidol has been researched along with Adenocarcinoma* in 1 studies
1 other study(ies) available for ailanthoidol and Adenocarcinoma
| Article | Year |
|---|---|
Estrogenic activity of phenylpropanoids from Sarcomelicope megistophylla and structure determination of a new norneolignan.
Bioassay-guided fractionation of the neutral extract of the bark of Sarcomelicope megistophylla resulted in the isolation of the new nor-neolignan sarcomeginal ( 1), together with the known ailanthoidol ( 2) and (+/-)-seco-isolariciresinol ( 3). The structure of 1 was determined by spectroscopic means. Estrogenic activity of the isolated compounds was tested using estrogen receptor-positive MCF7 and estrogen receptor-negative MDA-MB-231 human mammary adenocarcinoma cell lines. Compound 3 displayed significant estrogenic activity. Topics: Adenocarcinoma; Antineoplastic Agents, Hormonal; Benzofurans; Breast Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Inhibitory Concentration 50; Lignans; Lignin; Naphthols; Phytotherapy; Plant Bark; Plant Extracts; Receptors, Estrogen; Rutaceae; Tumor Cells, Cultured | 2003 |