Compounds > aica ribonucleotide

aica ribonucleotide and Obesity

aica ribonucleotide has been researched along with Obesity in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (39.29)29.6817
2010's13 (46.43)24.3611
2020's4 (14.29)2.80

Authors

AuthorsStudies
Hsu, CN; Tain, YL; Tsai, WL1
Chen, BB; Chen, Y; Finkel, T; Huckestein, BR; Jiang, Y; Jurczak, MJ; Kennerdell, JR; Larsen, MB; Lear, TB; Lin, B; Liu, Y; Mallampalli, RK; Monga, SP; Nguyen, MK; O'Donnell, CP; Tuncer, F1
Albuquerque, B; Andersen, NR; Birk, JB; Carling, D; Jørgensen, NO; Kjøbsted, R; Larsen, MR; Miller, R; Pehmøller, CK; Schjerling, P; Wojtaszewski, JFP1
Fu, CN; Gao, WS; Qu, YJ; Song, SS; Wei, H; Yue, SW1
Al-Hasani, H; Carling, D; Chadt, A; Gray, A; Hardie, DG; Heesom, KJ; Hook, SC; Tavaré, JM; Thomas, EC1
Hughey, CC; Hunter, RW; Jessen, N; Lantier, L; Peggie, M; Sakamoto, K; Sicheri, F; Sundelin, EI; Wasserman, DH; Zeqiraj, E1
Kovacova, Z; Polak, J; Rossmeislova, L; Siklova-Vitkova, M; Stich, V; Tencerova, M; Vedral, T; Wedellova, Z1
Choe, CU; Isbrandt, D; Neu, A; Sauter, K; Stockebrand, M1
Al-Hasani, H; Chadt, A; Dokas, J; Himmelbauer, H; Joost, HG; Nolden, T; Zierath, JR1
Declèves, AE; Farquhar, MG; Le, TP; Nakayama, T; Naviaux, RK; Nortier, JL; Rogac, M; Satriano, J; Sharma, K; Wang, L; Zolkipli, Z1
Azizi, PD; Chen, Z; Dyck, JR; Fullerton, MD; Galic, S; Hawke, TJ; Holloway, GP; Jorgensen, SB; Kemp, BE; Lally, JS; O'Neill, HM; Pulinilkunnil, T; Samaan, MC; Smith, BK; Steinberg, GR; Thomas, M; van Denderen, BJ1
Du, M; Foretz, M; Fu, X; Viollet, B; Zhang, S; Zhu, M1
Boß, M; Brüne, B; Collins, I; Gupta, S; Namgaladze, D; Newbatt, Y1
Costanzo-Garvey, DL; Guo, L; Lewis, RE; MacDonald, RG; Neilsen, BK; Smith, DR1
Anthony, NM; Ceddia, RB; Fediuc, S; Gaidhu, MP; Mirpourian, M; Perry, RL; So, M1
Hawley, JA; Holloszy, JO1
Bala, M; Buechler, C; Kopp, A; Lieberer, E; Neumeier, M; Schäffler, A; Sporrer, D; Stögbauer, F; Wanninger, J; Weber, M; Weigert, J1
Cameron-Smith, D; McAinch, AJ1
Beck Jørgensen, S; Hewitt, K; Kemp, BE; O'Neill, HM; Steinberg, GR1
Alway, SE; Drake, JC; Hollander, JM; Williamson, DL1
Aguer, C; Foretz, M; Hébrard, S; Kitzmann, M; Lantier, L; Mercier, J1
He, Y; Qi, L; Shi, H; Wang, X; Xue, B; Yang, Z; Yu, L1
Campbell, DJ; Chen, Z; Dyck, DJ; Heigenhauser, GJ; Kemp, BE; Murthy, S; Smith, AC; Steinberg, GR; Van Denderen, BJ1
Cameron-Smith, D; Chen, MB; Dixon, JB; Kemp, BE; McAinch, AJ; O'Brien, PE; Steinberg, GR1
Hardie, DG; Towler, MC1
Brauner, P; Drahota, Z; Flachs, P; Hensler, M; Houstek, J; Janovska, P; Jilkova, Z; Kopecky, J; Kuda, O; Kus, V; Medrikova, D; Pastalkova, E; Prazak, T; Rossmeisl, M; Stefl, B1
Bergeron, R; Cline, GW; Perret, P; Previs, SF; Russell, RR; Shulman, GI; Young, LH1
Chibalin, AV; Fernström, M; Fiedler, M; Galuska, D; Ryder, JW; Song, XM; Wallberg-Henriksson, H; Zierath, JR1

Reviews

2 review(s) available for aica ribonucleotide and Obesity

ArticleYear
Exercise: it's the real thing!
    Nutrition reviews, 2009, Volume: 67, Issue:3

    Topics: Aminoimidazole Carboxamide; Animals; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Energy Intake; Exercise; Gene Expression; Humans; Life Style; Mitochondria, Muscle; Muscle, Skeletal; Obesity; PPAR delta; Primary Prevention; Ribonucleotides

2009
AMP-activated protein kinase in metabolic control and insulin signaling.
    Circulation research, 2007, Feb-16, Volume: 100, Issue:3

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adipocytes; Amino Acid Sequence; Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Carbohydrate Metabolism; Cell Cycle; Consensus Sequence; Diabetes Mellitus; Energy Metabolism; Enzyme Activation; Hepatocytes; Humans; Hypoglycemic Agents; Insulin; Lipid Metabolism; Metformin; Mice; Mice, Knockout; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Muscle Cells; Neoplasms; Obesity; Oxygen Consumption; Peptide Hormones; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Subunits; Rats; Ribonucleotides; Sequence Alignment; Sequence Homology, Amino Acid

2007

Other Studies

26 other study(ies) available for aica ribonucleotide and Obesity

ArticleYear
Whether AICAR in Pregnancy or Lactation Prevents Hypertension Programmed by High Saturated Fat Diet: A Pilot Study.
    Nutrients, 2020, Feb-11, Volume: 12, Issue:2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animal Nutritional Physiological Phenomena; Animals; Diet, High-Fat; Fatty Acids; Female; Hypertension; Kidney; Lactation; Male; Nitric Oxide; Obesity; Oxidative Stress; Pilot Projects; Pregnancy; Rats, Sprague-Dawley; Ribonucleotides; Signal Transduction; Sirtuin 1

2020
A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance.
    Nature chemical biology, 2021, Volume: 17, Issue:3

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Line, Transformed; Diet, High-Fat; Epithelial Cells; F-Box Proteins; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Mice; Mice, Inbred C57BL; Mice, Obese; Mitochondrial Dynamics; Obesity; Phosphorylation; Polyubiquitin; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Protein Stability; Proteolysis; Ribonucleotides; Ubiquitin-Protein Ligases; Ubiquitination

2021
Direct small molecule ADaM-site AMPK activators reveal an AMPKγ3-independent mechanism for blood glucose lowering.
    Molecular metabolism, 2021, Volume: 51

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blood Glucose; Diet, High-Fat; Disease Models, Animal; Female; Humans; Mice; Mice, Knockout; Muscle, Skeletal; Obesity; Phosphorylation; Ribonucleotides; Signal Transduction

2021
Obesity increases neuropathic pain via the AMPK-ERK-NOX4 pathway in rats.
    Aging, 2021, 07-29, Volume: 13, Issue:14

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; Butadienes; Diet, High-Fat; Disease Models, Animal; Enzyme Inhibitors; Ganglia, Spinal; Hypoglycemic Agents; Inflammation; Male; MAP Kinase Signaling System; Metformin; NADPH Oxidase 4; Neuralgia; Nitriles; Obesity; Oxidative Stress; Pain Threshold; Phosphorylation; Rats, Wistar; Ribonucleotides; Spinal Cord

2021
Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity.
    The Biochemical journal, 2018, 09-25, Volume: 475, Issue:18

    Topics: Amino Acid Substitution; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Female; GTPase-Activating Proteins; Isoenzymes; Male; Mice; Mice, Transgenic; Mutation, Missense; Obesity; Phosphorylation; Ribonucleotides; Sex Characteristics

2018
Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase.
    Nature medicine, 2018, Volume: 24, Issue:9

    Topics: Adenosine Monophosphate; Aminoimidazole Carboxamide; Animals; Base Sequence; Chickens; Disease Models, Animal; Fructose-Bisphosphatase; Glucose; Glucose Intolerance; Homeostasis; Humans; Hypoglycemia; Liver; Metformin; Mice, Inbred C57BL; Mutation; Obesity; Prodrugs; Ribonucleotides

2018
The Impact of Full-Length, Trimeric and Globular Adiponectin on Lipolysis in Subcutaneous and Visceral Adipocytes of Obese and Non-Obese Women.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Adipocytes; Adiponectin; Adult; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Cells, Cultured; Female; Gene Expression; Humans; Hypoglycemic Agents; Intra-Abdominal Fat; Lipolysis; Middle Aged; Obesity; Protein Isoforms; Protein Multimerization; Real-Time Polymerase Chain Reaction; Receptors, Adiponectin; Ribonucleotides; Subcutaneous Fat

2013
Differential regulation of AMPK activation in leptin- and creatine-deficient mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:10

    Topics: Adipose Tissue, White; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blood Glucose; Creatine; Dietary Fats; Enzyme Activation; Leptin; Liver; Mice; Mice, Knockout; Muscle, Skeletal; Obesity; Ribonucleotides

2013
Conventional knockout of Tbc1d1 in mice impairs insulin- and AICAR-stimulated glucose uptake in skeletal muscle.
    Endocrinology, 2013, Volume: 154, Issue:10

    Topics: Aminoimidazole Carboxamide; Animals; Anti-Obesity Agents; Biological Transport; Carbon Dioxide; Diabetes Mellitus, Type 2; Disease Susceptibility; Energy Metabolism; Glucose; GTPase-Activating Proteins; Hypertriglyceridemia; Hypoglycemic Agents; Insulin Resistance; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Muscle, Skeletal; Nuclear Proteins; Obesity; Oxygen Consumption; Ribonucleotides

2013
Regulation of lipid accumulation by AMP-activated kinase [corrected] in high fat diet-induced kidney injury.
    Kidney international, 2014, Volume: 85, Issue:3

    Topics: Albuminuria; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cholesterol; Diet, High-Fat; Insulin Resistance; Kidney; Lipid Metabolism; Mice, Inbred C57BL; Mitochondria; Obesity; Ribonucleotides

2014
AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice.
    Diabetologia, 2014, Volume: 57, Issue:8

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Lipid Metabolism; Malonyl Coenzyme A; Mice; Muscle, Skeletal; Obesity; Oxidation-Reduction; Phosphorylation; Ribonucleotides

2014
Obesity Impairs Skeletal Muscle Regeneration Through Inhibition of AMPK.
    Diabetes, 2016, Volume: 65, Issue:1

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Differentiation; Cell Proliferation; Diet, High-Fat; Flow Cytometry; Hypoglycemic Agents; Immunoblotting; Immunohistochemistry; Mice; Mice, Knockout; Muscle Development; Muscle, Skeletal; Obesity; Regeneration; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleotides; Satellite Cells, Skeletal Muscle

2016
AMPK-independent inhibition of human macrophage ER stress response by AICAR.
    Scientific reports, 2016, 08-26, Volume: 6

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Cytokines; Endoplasmic Reticulum Stress; Endoribonucleases; Equilibrative Nucleoside Transporter 1; Humans; Macrophage Activation; Macrophages; Membrane Transport Proteins; Obesity; Phosphorylation; Protein Serine-Threonine Kinases; Ribonucleotides

2016
Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates energy balance and glucose homeostasis.
    Molecular metabolism, 2017, Volume: 6, Issue:2

    Topics: Aminoimidazole Carboxamide; Animals; Brain; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucose; Homeostasis; Insulin; Insulin Resistance; Male; Mice; Mice, Knockout; Obesity; Protein Serine-Threonine Kinases; Ribonucleotides; Signal Transduction

2017
Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL.
    Journal of lipid research, 2009, Volume: 50, Issue:4

    Topics: Adenylate Kinase; Adipocytes, White; Aminoimidazole Carboxamide; Animals; Base Sequence; DNA Primers; Energy Metabolism; Enzyme Activation; In Vitro Techniques; Lipase; Lipolysis; Male; Models, Biological; Obesity; Phosphorylation; Rats; Rats, Wistar; Ribonucleotides; RNA, Messenger; Sterol Esterase

2009
Adiponectin downregulates CD163 whose cellular and soluble forms are elevated in obesity.
    European journal of clinical investigation, 2009, Volume: 39, Issue:8

    Topics: Adiponectin; Adult; Aminoimidazole Carboxamide; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Diabetes Mellitus, Type 2; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Obesity; Receptors, Cell Surface; Ribonucleotides

2009
Adiponectin decreases pyruvate dehydrogenase kinase 4 gene expression in obese- and diabetic-derived myotubes.
    Diabetes, obesity & metabolism, 2009, Volume: 11, Issue:7

    Topics: Adiponectin; Adult; Aminoimidazole Carboxamide; Diabetes Mellitus; Electron Transport Complex IV; Female; Gene Expression; Humans; Hypoglycemic Agents; Male; Middle Aged; Mitochondria; Muscle Fibers, Skeletal; Obesity; Protein Kinases; Rectus Abdominis; Ribonucleotides; Thinness; Victoria

2009
Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity.
    Diabetologia, 2009, Volume: 52, Issue:11

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; Animals; Body Weight; Deoxyglucose; Dietary Fats; Insulin Resistance; Kinetics; Lipid Peroxidation; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Skeletal; Obesity; Protein Kinases; Reference Values; Ribonucleotides

2009
AICAR treatment for 14 days normalizes obesity-induced dysregulation of TORC1 signaling and translational capacity in fasted skeletal muscle.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:6

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Blood Glucose; Blotting, Western; Eukaryotic Initiation Factor-4G; Immunoprecipitation; Insulin; Male; Mice; Mice, Obese; Muscle, Skeletal; Obesity; Phosphorylation; Protein Biosynthesis; Ribonucleotides; Signal Transduction; Transcription Factors

2010
Abnormal metabolism flexibility in response to high palmitate concentrations in myotubes derived from obese type 2 diabetic patients.
    Biochimica et biophysica acta, 2011, Volume: 1812, Issue:4

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Cells, Cultured; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Lipid Metabolism; Metformin; Middle Aged; Mitochondria; Muscle Fibers, Skeletal; Obesity; Oxidation-Reduction; Palmitates; Phosphorylation; Quadriceps Muscle; Ribonucleotides

2011
The full capacity of AICAR to reduce obesity-induced inflammation and insulin resistance requires myeloid SIRT1.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Aminoimidazole Carboxamide; Animals; Diet, High-Fat; Glucose; Humans; Inflammation; Insulin; Insulin Resistance; Macrophage-1 Antigen; Mice; Mice, Knockout; Muscle, Skeletal; Myeloid Cells; Obesity; Ribonucleotides; Signal Transduction; Sirtuin 1

2012
AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:9

    Topics: Acetyl-CoA Carboxylase; Adenylate Kinase; Adult; Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; Down-Regulation; Fatty Acids; Female; Humans; Leptin; Middle Aged; Muscle, Skeletal; Obesity; Phosphorylation; Protein Kinases; Protein Subunits; Ribonucleotides; RNA, Messenger

2004
The suppressor of cytokine signaling 3 inhibits leptin activation of AMP-kinase in cultured skeletal muscle of obese humans.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:9

    Topics: Adenylate Kinase; Adult; Aminoimidazole Carboxamide; Enzyme Activation; Female; Humans; Hypoglycemic Agents; Leptin; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Palmitates; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleotides; RNA, Messenger; Signal Transduction; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins

2006
Induction of muscle thermogenesis by high-fat diet in mice: association with obesity-resistance.
    American journal of physiology. Endocrinology and metabolism, 2008, Volume: 295, Issue:2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Animals, Newborn; Basal Metabolism; Body Temperature; Body Weight; Calorimetry, Indirect; Dietary Fats; Fatty Acids, Nonesterified; Male; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Muscle, Skeletal; Obesity; Oxygen Consumption; Protein Serine-Threonine Kinases; Random Allocation; Ribonucleotides; Thermogenesis; Triglycerides

2008
Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats.
    Diabetes, 2001, Volume: 50, Issue:5

    Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Blood Glucose; Body Weight; Fatty Acids, Nonesterified; Glucose; Glycerol; Infusions, Intravenous; Injections, Intravenous; Insulin; Insulin Resistance; Lactates; Male; Models, Animal; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Reference Values; Ribonucleotides; Triglycerides

2001
5-Aminoimidazole-4-carboxamide ribonucleoside treatment improves glucose homeostasis in insulin-resistant diabetic (ob/ob) mice.
    Diabetologia, 2002, Volume: 45, Issue:1

    Topics: Aminoimidazole Carboxamide; Animals; Biological Transport; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose; Glucose Tolerance Test; Glycogen; Homeostasis; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Insulin Resistance; Liver; Liver Glycogen; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle, Skeletal; Obesity; Ribonucleotides

2002