Compounds > aica ribonucleotide

aica ribonucleotide and Lung Neoplasms

aica ribonucleotide has been researched along with Lung Neoplasms in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Aftab, F; Kobayashi, IS; Kobayashi, SS; Levantini, E; Politi, K; Rodriguez-Fuguet, A; Silva, L; Sun, J; Zhang, W; Zhang, WC1
Brooks, HB; Dally, RD; Durham, TB; Fales, KR; Foreman, RT; Frimpong, K; Geeganage, S; Hui, YH; Iversen, PW; Konicek, SA; Lee, MR; Luo, S; Mc Cowan, JR; Meier, TI; Njoroge, FG; Qian, YW; Roth, KD; Shepherd, TA; Si, C; Spencer, CD; Thibodeaux, S; Thrasher, KJ; Torrado, A; Toth, JL; Wang, T; Wang, Y; Wu, Z1
Chen, X; Gotoh, N; Horike, SI; Igarashi, K; Kato, K; Kita, K; Kohno, S; Meguro-Horike, M; Mukaida, N; Murayama, T; Nakata, A; Nishi, K; Nishimura, T; Saitoh, K; Sasaki, S; Soga, T; Takahashi, C; Tojo, A; Yano, S1
Han, S; Ritzenthaler, JD; Roman, J; Sun, X; Zheng, Y1
Heyer, CL; Moran, RG; Racanelli, AC; Rothbart, SB1

Other Studies

5 other study(ies) available for aica ribonucleotide and Lung Neoplasms

ArticleYear
An intrinsic purine metabolite AICAR blocks lung tumour growth by targeting oncoprotein mucin 1.
    British journal of cancer, 2023, Volume: 128, Issue:9

    Topics: Animals; Cell Line, Tumor; ErbB Receptors; Lung; Lung Neoplasms; Mice; Mice, Transgenic; Mucin-1; Oncogene Proteins; Purines

2023
Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models.
    Scientific reports, 2018, 10-18, Volume: 8, Issue:1

    Topics: Aminoimidazole Carboxamide; Animals; Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; Female; Humans; Hydroxymethyl and Formyl Transferases; Lung Neoplasms; Mice; Mice, Nude; Multienzyme Complexes; Neoplasm Proteins; Nucleotide Deaminases; Ribonucleotides; Xenograft Model Antitumor Assays

2018
Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.
    Oncogene, 2019, Volume: 38, Issue:14

    Topics: Aminohydrolases; Aminoimidazole Carboxamide; beta Catenin; Carcinogenesis; Cell Line; Cell Line, Tumor; Drug Resistance, Neoplasm; Folic Acid; Gefitinib; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lung Neoplasms; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Multifunctional Enzymes; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Purines; Ribonucleotides

2019
Activation of peroxisome proliferator-activated receptor beta/delta induces lung cancer growth via peroxisome proliferator-activated receptor coactivator gamma-1alpha.
    American journal of respiratory cell and molecular biology, 2009, Volume: 40, Issue:3

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Heat-Shock Proteins; Humans; Lung Neoplasms; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphatidylinositol 3-Kinases; Phosphorylation; PPAR delta; PPAR-beta; Ribonucleotides; RNA, Small Interfering; Signal Transduction; Thiazoles; Transcription Factors

2009
Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target of rapamycin inhibition.
    Cancer research, 2009, Jul-01, Volume: 69, Issue:13

    Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Division; Enzyme Activation; Folic Acid Antagonists; Glutamates; Glycine; Guanine; Humans; Kinetics; Lung Neoplasms; Mesothelioma; Pemetrexed; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinases; Ribonucleotides; TOR Serine-Threonine Kinases

2009