aica ribonucleotide has been researched along with Inflammation in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.67) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 23 (76.67) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Duan, X; Gao, Z; Wu, Y; Xue, F; Yang, N | 1 |
| Fu, CN; Gao, WS; Qu, YJ; Song, SS; Wei, H; Yue, SW | 1 |
| Cieslik, KA; Entman, ML; Trial, J | 1 |
| Hosaka, T; Ishida, H; Kitahara, A; Kondo, T; Morita, N; Murashima, T; Onuma, H; Sumitani, Y; Takahashi, K; Tanaka, T | 1 |
| Bedard, N; Di Marco, S; Ford, RJ; Gallouzi, IE; Griss, T; Hall, DT; Jones, RG; Ma, JF; Mubaid, S; Omer, A; Pause, A; Sadek, J; Sanchez, BJ; Steinberg, GR; Tremblay, AMK; Wing, SS | 1 |
| Hu, L; Hu, XF; Li, HP; Li, M; Lin, LX; Liu, WT; Pan, HL; Shu, Y; Xiang, HC; Zhang, RY; Zhao, YL; Zhu, H | 1 |
| Geisslinger, G; Martin, LM; Möller, M; Niederberger, E; Pierre, S; Russe, OQ; Scholich, K; Weiss, U | 1 |
| Barroso, E; Coll, T; Gómez-Foix, AM; Palomer, X; Salmerón, E; Salvadó, L; Vázquez-Carrera, M | 1 |
| Brüne, B; Kemmerer, M; Namgaladze, D; von Knethen, A | 1 |
| Geisslinger, G; King, TS; Kynast, KL; Möser, CV; Niederberger, E; Russe, OQ; Stephan, H | 1 |
| Amrutkar, M; Cansby, E; Durán, EN; Mahlapuu, M; Nerstedt, A; Smith, U | 1 |
| Kamoshita, M; Kubota, S; Miyake, S; Nagai, N; Ozawa, Y; Shimmura, S; Tsubota, K; Tsuda, C; Umezawa, K; Yuki, K | 1 |
| Botero-Quintero, AM; Darwiche, S; Escobar, DA; Gomez, H; Kautza, BC; Loughran, P; Luciano, J; Rosengart, MR; Zuckerbraun, BS | 1 |
| Chen, W; Huang, F; Kou, J; Li, J; Liu, B; Liu, K; Ma, XN; Qi, LW; Wang, Y; Wen, X | 1 |
| Coppa, GF; Khan, MM; Marambaud, P; Mulchandani, N; Nicastro, J; Wang, P; Yang, WL; Zhang, F | 1 |
| Chen, CC; Chen, HM; Chen, PK; Cheng, YF; Jang, HH; Kao, SH; Kuo, CY; Liang, YJ; Lin, JT; Nong, JY; Young, GH | 1 |
| Chen, J; Li, XG; Wang, W; Xu, J | 1 |
| Cheng, XY; Huang, C; Li, J; Li, YY; Yao, HW | 1 |
| Abraham, E; Liu, G; Lorne, E; Park, YJ; Tsuruta, Y; Zhao, X; Zmijewski, JW | 1 |
| Andris, F; Baus, E; Denanglaire, S; Flavell, RA; Leo, O; Rongvaux, A; Steuve, J | 1 |
| Qiu, J; Wang, X; Xia, M; Zhang, Y | 1 |
| Ishida, S; Kubota, S; Kurihara, T; Miyake, S; Noda, K; Ozawa, Y; Sasaki, M; Tsubota, K; Yuki, K | 1 |
| Atkins, AR; Coulter, S; Downes, M; Evans, RM; Liddle, C; Rao, R; Sherman, MH; Subramaniam, N; Wilson, C | 1 |
| He, Y; Qi, L; Shi, H; Wang, X; Xue, B; Yang, Z; Yu, L | 1 |
| Cheng, S; Hao, J; Ji, G; Jiang, Z; Yang, Q; Zhang, Y; Zhao, X | 1 |
| Coughlan, K; Moriasi, C; Viollet, B; Wang, Q; Xing, J; Zou, MH | 1 |
| Giri, S; Nath, N; Singh, AK; Singh, I; Smith, B; Viollet, B | 1 |
| Cronstein, BN; Naime, D; Ostad, E | 2 |
| Croce, MA; Davis, KA; Fabian, TC; Proctor, KG; Ragsdale, DN; Trenthem, LL | 1 |
30 other study(ies) available for aica ribonucleotide and Inflammation
| Article | Year |
|---|---|
AICAR attenuates postoperative abdominal adhesion formation by inhibiting oxidative stress and promoting mesothelial cell repair.
Topics: Aminoimidazole Carboxamide; Animals; Cadherins; Catalase; Hyaluronic Acid; Inflammation; NF-E2-Related Factor 2; Oxidative Stress; Rats; Reactive Oxygen Species; Ribonucleosides; Ribonucleotides; RNA, Messenger; Superoxide Dismutase; Tissue Adhesions; Transforming Growth Factor beta1; Vimentin | 2022 |
Obesity increases neuropathic pain via the AMPK-ERK-NOX4 pathway in rats.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; Butadienes; Diet, High-Fat; Disease Models, Animal; Enzyme Inhibitors; Ganglia, Spinal; Hypoglycemic Agents; Inflammation; Male; MAP Kinase Signaling System; Metformin; NADPH Oxidase 4; Neuralgia; Nitriles; Obesity; Oxidative Stress; Pain Threshold; Phosphorylation; Rats, Wistar; Ribonucleotides; Spinal Cord | 2021 |
Aicar treatment reduces interstitial fibrosis in aging mice: Suppression of the inflammatory fibroblast.
Topics: Aging; Aminoimidazole Carboxamide; Animals; Biomarkers; Cell Count; Fibroblasts; Fibrosis; Inflammation; Male; Mice, Inbred C57BL; Myocardium; Ribonucleotides | 2017 |
Novel Mechanisms Modulating Palmitate-Induced Inflammatory Factors in Hypertrophied 3T3-L1 Adipocytes by AMPK.
Topics: 3T3-L1 Cells; Adenylate Kinase; Adipocytes; Aminoimidazole Carboxamide; Animals; Chemokine CCL2; Inflammation; Metformin; Mice; NF-kappa B; Palmitic Acid; Phosphorylation; Ribonucleotides; Signal Transduction; Triglycerides | 2018 |
The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; Animals; Cachexia; Cell Line; Enzyme Activation; Inflammation; Interferon-gamma; Male; Metformin; Mice, Inbred BALB C; Mitochondria; Muscle, Skeletal; Neoplasms, Experimental; Nitric Oxide Synthase Type II; Protein Kinases; Ribonucleotides; Shock, Septic; Tumor Necrosis Factor-alpha | 2018 |
AMPK activation attenuates inflammatory pain through inhibiting NF-κB activation and IL-1β expression.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; CX3C Chemokine Receptor 1; Disease Models, Animal; Enzyme Activation; Freund's Adjuvant; Gene Expression Regulation; Hypoglycemic Agents; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Pain; Pain Threshold; Ribonucleotides; RNA, Small Interfering; Skin | 2019 |
5-Amino-1-β-D-Ribofuranosyl-Imidazole-4-Carboxamide (AICAR) Reduces Peripheral Inflammation by Macrophage Phenotype Shift.
Topics: Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents; Cells, Cultured; Edema; Hyperalgesia; Inflammation; Macrophages; Male; Mice, Inbred C57BL; Ribonucleotides | 2019 |
Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Biphenyl Compounds; Cell Line; Cell Nucleus; Chromatography, High Pressure Liquid; Endoplasmic Reticulum; Humans; Inflammation; Insulin Resistance; Lipids; Mice; Muscle Cells; Muscle, Skeletal; NF-kappa B; Oleic Acid; Palmitic Acid; Pyrones; Ribonucleotides; Signal Transduction; Thiophenes | 2013 |
AICAR inhibits PPARγ during monocyte differentiation to attenuate inflammatory responses to atherogenic lipids.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Atherosclerosis; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Enzyme Activation; Enzyme Activators; Gene Expression Regulation; Humans; Inflammation; Interleukin-4; JNK Mitogen-Activated Protein Kinases; Lipoproteins, LDL; Macrophages; Monocytes; Palmitic Acid; Phenotype; PPAR gamma; Ribonucleotides; RNA Interference; RNA, Messenger; Transfection | 2013 |
Activation of the AMP-activated protein kinase reduces inflammatory nociception.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Behavior, Animal; Enzyme Activation; Hyperalgesia; Inflammation; Male; Metformin; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Skills; Nociception; Pain Measurement; Ribonucleotides; Rotarod Performance Test | 2013 |
Partial hepatic resistance to IL-6-induced inflammation develops in type 2 diabetic mice, while the anti-inflammatory effect of AMPK is maintained.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Blood Glucose; Blotting, Western; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Inflammation; Interleukin-6; Liver; Male; Metformin; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Ribonucleotides | 2014 |
AMPK-NF-κB axis in the photoreceptor disorder during retinal inflammation.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Electroretinography; Inflammation; Male; Mice; NF-kappa B; Photoreceptor Cells; Retinal Diseases; Rhodopsin; Ribonucleotides; Signal Transduction | 2014 |
Adenosine monophosphate-activated protein kinase activation protects against sepsis-induced organ injury and inflammation.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Autophagy; Cell Adhesion; Cells, Cultured; Cytokines; Endothelial Cells; Inflammation; Leukocytes; Male; Mice; Mice, Inbred C57BL; Multiple Organ Failure; Ribonucleotides; Sepsis | 2015 |
Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carrier Proteins; Caspase 1; Cell Cycle Proteins; Dynamins; Endoplasmic Reticulum Stress; Endothelium, Vascular; Gene Expression Regulation; Humans; Inflammation; Interleukin-1beta; Mitochondrial Dynamics; Rats; Ribonucleotides; Salicylates; Vasodilation | 2015 |
Stimulation of Brain AMP-Activated Protein Kinase Attenuates Inflammation and Acute Lung Injury in Sepsis.
Topics: Acute Lung Injury; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Cell Survival; Energy Metabolism; Gene Expression Regulation; Humans; Inflammation; Male; Mice; Phosphorylation; Ribonucleotides; Sepsis | 2015 |
Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Cell Adhesion; Cells, Cultured; Enzyme Activation; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Monocytes; NF-kappa B; Phosphorylation; Protein Transport; Ribonucleotides; RNA, Small Interfering; Tumor Necrosis Factor-alpha | 2015 |
Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
Topics: Adrenergic beta-2 Receptor Agonists; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anti-Inflammatory Agents; beta-Arrestin 2; Cell Line, Tumor; Enzyme Activation; Fenoterol; Humans; Inflammation; Inflammation Mediators; Monocytes; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Ribonucleotides; RNA Interference; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha | 2016 |
AMP-activated protein kinase reduces inflammatory responses and cellular senescence in pulmonary emphysema.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Line; Cellular Senescence; Energy Metabolism; Female; Humans; Inflammation; Lipid Metabolism; Lung; Male; Mice; Mice, Inbred C57BL; Pancreatic Elastase; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Pyrazoles; Pyrimidines; Respiratory Mucosa; Ribonucleotides; Smoking | 2017 |
Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury.
Topics: Acute Disease; Aminoimidazole Carboxamide; Animals; Cyclic AMP-Dependent Protein Kinases; Cytokines; Enzyme Activation; Inflammation; Lipopolysaccharides; Lung; Lung Injury; Male; Mice; Mice, Inbred C57BL; Neutrophils; NF-kappa B; Ribonucleotides; Toll-Like Receptor 4 | 2008 |
Metabolic stress boosts humoral responses in vivo independently of inflammasome and inflammatory reaction.
Topics: Adenosine Triphosphate; Adjuvants, Immunologic; Aminoimidazole Carboxamide; Animals; Carrier Proteins; Cells, Cultured; Immunoglobulin G; Inflammasomes; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Oligomycins; Ribonucleotides; Stress, Physiological; Up-Regulation | 2011 |
AMP-activated protein kinase suppresses endothelial cell inflammation through phosphorylation of transcriptional coactivator p300.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Aorta; Cell Adhesion; Cells, Cultured; E1A-Associated p300 Protein; Endothelium, Vascular; Gene Expression Regulation; Histone Acetyltransferases; Humans; Inflammation; Monocytes; NF-kappa B; Phosphorylation; Protein Kinase C; Ribonucleotides; Vascular Cell Adhesion Molecule-1 | 2011 |
Roles of AMP-activated protein kinase in diabetes-induced retinal inflammation.
Topics: Administration, Oral; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Inflammation; Injections, Intraperitoneal; Intercellular Adhesion Molecule-1; Mice; Mice, Inbred C57BL; Phosphorylation; Resveratrol; Retinitis; Ribonucleotides; Sirtuin 1; Stilbenes; Transcription Factor RelA; Vascular Endothelial Growth Factor A | 2011 |
Metformin-mediated Bambi expression in hepatic stellate cells induces prosurvival Wnt/β-catenin signaling.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; beta Catenin; Hepatic Stellate Cells; Humans; Hypoglycemic Agents; Inflammation; Lipopolysaccharides; Male; Membrane Proteins; Metformin; Rats; Rats, Sprague-Dawley; Ribonucleotides; Signal Transduction; Wnt Proteins | 2012 |
The full capacity of AICAR to reduce obesity-induced inflammation and insulin resistance requires myeloid SIRT1.
Topics: Aminoimidazole Carboxamide; Animals; Diet, High-Fat; Glucose; Humans; Inflammation; Insulin; Insulin Resistance; Macrophage-1 Antigen; Mice; Mice, Knockout; Muscle, Skeletal; Myeloid Cells; Obesity; Ribonucleotides; Signal Transduction; Sirtuin 1 | 2012 |
Genistein suppresses LPS-induced inflammatory response through inhibiting NF-κB following AMP kinase activation in RAW 264.7 macrophages.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Cell Line; Dose-Response Relationship, Drug; Genistein; Inflammation; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Ribonucleotides; Signal Transduction; Tumor Necrosis Factor-alpha | 2012 |
Inhibition of AMP-activated protein kinase accentuates lipopolysaccharide-induced lung endothelial barrier dysfunction and lung injury in vivo.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Antigens, CD; Blood Vessels; Cadherins; Cattle; cdc42 GTP-Binding Protein; Cell Membrane Permeability; Cells, Cultured; Endothelial Cells; Enzyme Activation; Humans; Inflammation; Lipopolysaccharides; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Myosin Light Chains; p21-Activated Kinases; Phosphoprotein Phosphatases; Phosphorylation; Phosphothreonine; Protein Phosphatase 2C; Protein Serine-Threonine Kinases; rac1 GTP-Binding Protein; Ribonucleotides; Signal Transduction | 2013 |
5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase.
Topics: Active Transport, Cell Nucleus; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Cell Nucleus; Cells, Cultured; Cytokines; Inflammation; Lipopolysaccharides; Macrophages, Peritoneal; Multienzyme Complexes; Neuroglia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Ribonucleotides; Transcription Factors | 2004 |
The antiinflammatory effects of methotrexate are mediated by adenosine.
Topics: Acyltransferases; Adenosine; Adenosine Deaminase; Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Hydroxymethyl and Formyl Transferases; Inflammation; Kinetics; Leukocytes; Methotrexate; Mice; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Purinergic P1 Receptor Antagonists; Ribonucleotides; Theobromine; Xanthines | 1994 |
The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.
Topics: Adenosine; Adenosine Deaminase; Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Female; Inflammation; Kinetics; Leukocytes; Methotrexate; Mice; Mice, Inbred BALB C; Purinergic P1 Receptor Antagonists; Ribonucleotides; Spleen; Theobromine; Time Factors | 1993 |
Combination therapy that targets secondary pulmonary changes after abdominal trauma.
Topics: Abdominal Abscess; Abdominal Injuries; Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents; Blood Pressure; Capillaries; Disease Models, Animal; Hemodynamics; Inflammation; Lactates; Lung; Lung Injury; Neutrophils; Pulmonary Alveoli; Pulmonary Artery; Resuscitation; Ribonucleotides; Shock, Hemorrhagic; Steroids; Swine | 2001 |