ahr-5850 has been researched along with Inflammation* in 1 studies
1 other study(ies) available for ahr-5850 and Inflammation
| Article | Year |
|---|---|
Antiinflammatory agents. 4. Syntheses and biological evaluation of potential prodrugs of 2-amino-3-benzoylbenzeneacetic acid and 2-amino-3-(4-chlorobenzoyl)benzeneacetic acid.
A series of potential prodrugs of 2-amino-3-benzoylbenzeneacetic acid (amfenac) and 2-amino-3-(4-chlorobenzoyl)benzeneacetic acid were synthesized and evaluated for their cyclooxygenase inhibiting properties, antiinflammatory potency, and gastrointestinal irritation liability. One compound, 2-amino-3-(4-chlorobenzoyl)benzeneacetamide, possessed a therapeutic index 1 order of magnitude greater than that of indomethacin. Topics: Acetamides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzeneacetamides; Carrageenan; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Female; Gastrointestinal Diseases; Indomethacin; Inflammation; Male; Molecular Structure; Phenylacetates; Prodrugs; Rats | 1990 |