agmatine has been researched along with Parkinson Disease in 3 studies
Agmatine: Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this report, we utilize FTIR spectroscopy to characterize the changes in rotenone-induced damage in neuronal-like differentiated SH-SY5Y neuroblastoma cells in the presence or absence of agmatine." | 7.78 | Protective effects of agmatine in rotenone-induced damage of human SH-SY5Y neuroblastoma cells: fourier transform infrared spectroscopy analysis in a model of Parkinson's disease. ( Caccamo, D; Calabrò, E; Condello, S; Currò, M; Ferlazzo, N; Ientile, R; Magazù, S; Satriano, J, 2012) |
| " In this report, we utilize FTIR spectroscopy to characterize the changes in rotenone-induced damage in neuronal-like differentiated SH-SY5Y neuroblastoma cells in the presence or absence of agmatine." | 3.78 | Protective effects of agmatine in rotenone-induced damage of human SH-SY5Y neuroblastoma cells: fourier transform infrared spectroscopy analysis in a model of Parkinson's disease. ( Caccamo, D; Calabrò, E; Condello, S; Currò, M; Ferlazzo, N; Ientile, R; Magazù, S; Satriano, J, 2012) |
| " Such movements are considered restrictive problem associated with the chronic use of L-dopa in Parkinson's disease (PD) treatment; the thing that renders the definite pathological mechanism unclear." | 1.72 | Agmatine-mediated inhibition of NMDA receptor expression and amelioration of dyskinesia via activation of Nrf2 and suppression of HMGB1/RAGE/TLR4/MYD88/NF-κB signaling cascade in rotenone lesioned rats. ( Azar, YO; Badawi, GA; Ibrahim, SM; Zaki, HF, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Azar, YO | 1 |
| Badawi, GA | 1 |
| Zaki, HF | 1 |
| Ibrahim, SM | 1 |
| Bilge, SS | 1 |
| Günaydin, C | 1 |
| Önger, ME | 1 |
| Bozkurt, A | 1 |
| Avci, B | 1 |
| Condello, S | 1 |
| Calabrò, E | 1 |
| Caccamo, D | 1 |
| Currò, M | 1 |
| Ferlazzo, N | 1 |
| Satriano, J | 1 |
| Magazù, S | 1 |
| Ientile, R | 1 |
3 other studies available for agmatine and Parkinson Disease
| Article | Year |
|---|---|
Agmatine-mediated inhibition of NMDA receptor expression and amelioration of dyskinesia via activation of Nrf2 and suppression of HMGB1/RAGE/TLR4/MYD88/NF-κB signaling cascade in rotenone lesioned rats.
Topics: Agmatine; Animals; Antioxidants; Dyskinesias; HMGB1 Protein; Levodopa; Myeloid Differentiation Facto | 2022 |
Neuroprotective action of agmatine in rotenone-induced model of Parkinson's disease: Role of BDNF/cREB and ERK pathway.
Topics: Agmatine; Animals; Apoptosis; Brain; Brain-Derived Neurotrophic Factor; Cell Survival; Corpus Striat | 2020 |
Protective effects of agmatine in rotenone-induced damage of human SH-SY5Y neuroblastoma cells: fourier transform infrared spectroscopy analysis in a model of Parkinson's disease.
Topics: Agmatine; Cell Line, Tumor; Humans; Models, Biological; Neuroblastoma; Parkinson Disease; Rotenone; | 2012 |