Page last updated: 2024-10-16

agmatine and Neuralgia

agmatine has been researched along with Neuralgia in 6 studies

Agmatine: Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle.

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
"L-Arginine supplementation prevented the development of mechanical hyperalgesia, tactile, and thermal allodynia in painful diabetic neuropathy with concomitant reduction of NO and increased agmatine production, offering new therapeutic opportunities for the management of diabetic neuropathic pain."7.88L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration. ( Courteix, C; Davin, N; Eschalier, A; Farges, MC; Privat, AM; Rondón, LJ; Sion, B; Vasson, MP, 2018)
"L-Arginine supplementation prevented the development of mechanical hyperalgesia, tactile, and thermal allodynia in painful diabetic neuropathy with concomitant reduction of NO and increased agmatine production, offering new therapeutic opportunities for the management of diabetic neuropathic pain."3.88L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration. ( Courteix, C; Davin, N; Eschalier, A; Farges, MC; Privat, AM; Rondón, LJ; Sion, B; Vasson, MP, 2018)
" Recent clinical studies have already shown that oral agmatine sulfate given for up to 3 weeks provides a safe and, as compared with current therapeutics, more effective treatment for neuropathic pain."1.40Long-term (5 years), high daily dosage of dietary agmatine--evidence of safety: a case report. ( Gilad, GM; Gilad, VH, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Rosenberg, ML1
Tohidi, V1
Sherwood, K1
Gayen, S1
Medel, R1
Gilad, GM2
Rondón, LJ1
Farges, MC1
Davin, N1
Sion, B1
Privat, AM1
Vasson, MP1
Eschalier, A1
Courteix, C1
Laube, G1
Bernstein, HG1
Akasaka, N1
Fujiwara, S1
Kotagale, NR1
Shirbhate, SH1
Shukla, P1
Ugale, RR1
Gilad, VH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Nutritional Supplementation With Agmatine Sulfate During Small Fiber Neuropathy[NCT01524666]15 participants (Anticipated)Observational2012-02-29Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for agmatine and Neuralgia

ArticleYear
Agmatine: multifunctional arginine metabolite and magic bullet in clinical neuroscience?
    The Biochemical journal, 2017, 07-26, Volume: 474, Issue:15

    Topics: Aging; Agmatine; Animals; Arginine; Central Nervous System Diseases; Humans; Mental Disorders; Metab

2017
The therapeutic and nutraceutical potential of agmatine, and its enhanced production using Aspergillus oryzae.
    Amino acids, 2020, Volume: 52, Issue:2

    Topics: Agmatine; Animals; Aspergillus oryzae; Depression; Dietary Supplements; Humans; Metabolic Diseases;

2020

Trials

1 trial available for agmatine and Neuralgia

ArticleYear
Evidence for Dietary Agmatine Sulfate Effectiveness in Neuropathies Associated with Painful Small Fiber Neuropathy. A Pilot Open-Label Consecutive Case Series Study.
    Nutrients, 2020, Feb-23, Volume: 12, Issue:2

    Topics: Aged; Aged, 80 and over; Agmatine; Diet; Female; Humans; Male; Middle Aged; Neuralgia; Pain Measurem

2020

Other Studies

3 other studies available for agmatine and Neuralgia

ArticleYear
L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration.
    European journal of nutrition, 2018, Volume: 57, Issue:7

    Topics: Administration, Oral; Agmatine; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Neuropa

2018
Agmatine attenuates neuropathic pain in sciatic nerve ligated rats: modulation by hippocampal sigma receptors.
    European journal of pharmacology, 2013, Aug-15, Volume: 714, Issue:1-3

    Topics: Agmatine; Animals; Female; Hippocampus; Ligation; Male; Neuralgia; Nociception; Rats; Rats, Sprague-

2013
Long-term (5 years), high daily dosage of dietary agmatine--evidence of safety: a case report.
    Journal of medicinal food, 2014, Volume: 17, Issue:11

    Topics: Administration, Oral; Agmatine; Diet; Dietary Supplements; Female; Health Status; Humans; Male; Midd

2014