Page last updated: 2024-10-16

agmatine and Nerve Degeneration

agmatine has been researched along with Nerve Degeneration in 6 studies

Agmatine: Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"Agmatine is an endogenous guanido amine and has been shown to be neuroprotective in vitro and in vivo."1.32Effect of agmatine against cell death induced by NMDA and glutamate in neurons and PC12 cells. ( Halaris, A; Piletz, JE; Regunathan, S; Zhu, MY, 2003)
"Agmatine treatment was found to accelerate recovery of motor deficits and to prevent the loss of motoneurons in the spinal cord after transient ischemia."1.31Accelerated functional recovery and neuroprotection by agmatine after spinal cord ischemia in rats. ( Gilad, GM; Gilad, VH, 2000)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kotagale, NR1
Taksande, BG1
Inamdar, NN1
Zhu, MY2
Wang, WP1
Huang, J1
Feng, YZ1
Regunathan, S2
Bissette, G1
Piletz, JE1
Halaris, A1
Yang, MZ1
Mun, CH1
Choi, YJ1
Baik, JH1
Park, KA1
Lee, WT1
Lee, JE1
Yu, CG1
Marcillo, AE1
Fairbanks, CA1
Wilcox, GL1
Yezierski, RP1
Gilad, GM1
Gilad, VH1

Reviews

1 review available for agmatine and Nerve Degeneration

ArticleYear
Neuroprotective offerings by agmatine.
    Neurotoxicology, 2019, Volume: 73

    Topics: Agmatine; Animals; Brain; Cell Death; Humans; Nerve Degeneration; Neurodegenerative Diseases; Neuron

2019

Other Studies

5 other studies available for agmatine and Nerve Degeneration

ArticleYear
Repeated immobilization stress alters rat hippocampal and prefrontal cortical morphology in parallel with endogenous agmatine and arginine decarboxylase levels.
    Neurochemistry international, 2008, Volume: 53, Issue:6-8

    Topics: Agmatine; Animals; Carboxy-Lyases; Corticosterone; Glutamic Acid; Hippocampus; Male; Nerve Degenerat

2008
Effect of agmatine against cell death induced by NMDA and glutamate in neurons and PC12 cells.
    Cellular and molecular neurobiology, 2003, Volume: 23, Issue:4-5

    Topics: Agmatine; Animals; Calcimycin; Cell Death; Cerebral Cortex; Enzyme Inhibitors; Fetus; Glutamic Acid;

2003
Agmatine inhibits matrix metalloproteinase-9 via endothelial nitric oxide synthase in cerebral endothelial cells.
    Neurological research, 2007, Volume: 29, Issue:7

    Topics: Agmatine; Animals; Brain Ischemia; Cell Death; Cells, Cultured; Cerebral Arteries; Down-Regulation;

2007
Agmatine improves locomotor function and reduces tissue damage following spinal cord injury.
    Neuroreport, 2000, Sep-28, Volume: 11, Issue:14

    Topics: Agmatine; Animals; Disease Models, Animal; Female; Gait Disorders, Neurologic; Myelitis; Nerve Degen

2000
Accelerated functional recovery and neuroprotection by agmatine after spinal cord ischemia in rats.
    Neuroscience letters, 2000, Dec-22, Volume: 296, Issue:2-3

    Topics: Agmatine; Animals; Cell Survival; Male; Motor Activity; Motor Neurons; Nerve Degeneration; Neuroprot

2000