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agmatine and Innate Inflammatory Response

agmatine has been researched along with Innate Inflammatory Response in 19 studies

Agmatine: Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle.

Research Excerpts

ExcerptRelevanceReference
" This study evaluates the effects of agmatine on ovalbumin (OVA)-induced allergic inflammation of the airways."8.12Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study. ( Abdelaziz, RR; Elmahdi, HS; Suddek, GM; Еlmahdy, MK, 2022)
"The present study investigated the pharmacological effect of agmatine in Complete Freud Adjuvant (CFA) induced arthritis and cachexia in rats."7.85Agmatine ameliorates adjuvant induced arthritis and inflammatory cachexia in rats. ( Chopde, CT; Gawande, DY; Kotagale, NR; Taksande, BG; Umekar, MJ, 2017)
"To examine the protective effects of agmatine (AGM) administration on zymosan (ZYM)-induced inflammatory response and acute lung injury (ALI) in mice."7.77[The protective effects of agmatine in zymosan induced acute lung injury in mice]. ( Bao, YX; Fan, X; Gu, Y; Liang, HP; Yang, X; Zhang, C, 2011)
"The present study examined the anti-hypernociceptive effects of agmatine (AGM) in acute and chronic models of behavioural pain in mice."7.74Anti-hypernociceptive properties of agmatine in persistent inflammatory and neuropathic models of pain in mice. ( Calixto, JB; Gadotti, VM; Paszcuk, AF; Quintão, NL; Rodrigues, AL; Santos, AR; Tibola, D, 2007)
"Agmatine accumulation was a direct result of mutations in aguA, encoding the arginine deiminase that catalyses the conversion of agmatine into various polyamines."5.51Agmatine accumulation by Pseudomonas aeruginosa clinical isolates confers antibiotic tolerance and dampens host inflammation. ( Evert, C; Gilbertsen, AJ; Hunter, RC; McCurtain, JL; Williams, BJ, 2019)
"The treatment with agmatine appeared to be significantly effective in reducing the MDA content and MPO activity besides restoring the content of GSH."5.46Agmatine attenuates intestinal ischemia and reperfusion injury by reducing oxidative stress and inflammatory reaction in rats. ( Araslı, M; Barut, F; Ozacmak, HS; Ozacmak, VH; Turan, I, 2017)
"Agmatine pretreatment was found to dose-dependently attenuate the thermal hyperalgesia induced by intraplantar carrageenan."5.30Effect of intrathecal agmatine on inflammation-induced thermal hyperalgesia in rats. ( Benedek, G; Dobos, I; Horváth, G; Kékesi, G; Klimscha, W; Szikszay, M, 1999)
" This study evaluates the effects of agmatine on ovalbumin (OVA)-induced allergic inflammation of the airways."4.12Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study. ( Abdelaziz, RR; Elmahdi, HS; Suddek, GM; Еlmahdy, MK, 2022)
"The present study investigated the pharmacological effect of agmatine in Complete Freud Adjuvant (CFA) induced arthritis and cachexia in rats."3.85Agmatine ameliorates adjuvant induced arthritis and inflammatory cachexia in rats. ( Chopde, CT; Gawande, DY; Kotagale, NR; Taksande, BG; Umekar, MJ, 2017)
"To examine the protective effects of agmatine (AGM) administration on zymosan (ZYM)-induced inflammatory response and acute lung injury (ALI) in mice."3.77[The protective effects of agmatine in zymosan induced acute lung injury in mice]. ( Bao, YX; Fan, X; Gu, Y; Liang, HP; Yang, X; Zhang, C, 2011)
"Painful reaction of rats to intraperitoneal injections of L-arginine, Nw-nitro-L-arginine, and agmatine was studied on the model of formalin-induced inflammation."3.74Effects of NO-modulating agents on the development of acute painful reaction in rats. ( Dyuizen, IV; Lamash, NE, 2008)
"The present study examined the anti-hypernociceptive effects of agmatine (AGM) in acute and chronic models of behavioural pain in mice."3.74Anti-hypernociceptive properties of agmatine in persistent inflammatory and neuropathic models of pain in mice. ( Calixto, JB; Gadotti, VM; Paszcuk, AF; Quintão, NL; Rodrigues, AL; Santos, AR; Tibola, D, 2007)
"Agmatine is an antiproliferative molecule due to its suppressive effects on intracellular polyamine levels, whereas the aldehyde metabolite of agmatine is a potent inhibitor of iNOS."2.42Agmatine: at the crossroads of the arginine pathways. ( Satriano, J, 2003)
"Agmatine accumulation was a direct result of mutations in aguA, encoding the arginine deiminase that catalyses the conversion of agmatine into various polyamines."1.51Agmatine accumulation by Pseudomonas aeruginosa clinical isolates confers antibiotic tolerance and dampens host inflammation. ( Evert, C; Gilbertsen, AJ; Hunter, RC; McCurtain, JL; Williams, BJ, 2019)
"The treatment with agmatine appeared to be significantly effective in reducing the MDA content and MPO activity besides restoring the content of GSH."1.46Agmatine attenuates intestinal ischemia and reperfusion injury by reducing oxidative stress and inflammatory reaction in rats. ( Araslı, M; Barut, F; Ozacmak, HS; Ozacmak, VH; Turan, I, 2017)
"Agmatine pretreatment was found to dose-dependently attenuate the thermal hyperalgesia induced by intraplantar carrageenan."1.30Effect of intrathecal agmatine on inflammation-induced thermal hyperalgesia in rats. ( Benedek, G; Dobos, I; Horváth, G; Kékesi, G; Klimscha, W; Szikszay, M, 1999)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.53)18.2507
2000's5 (26.32)29.6817
2010's9 (47.37)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Milosevic, K1
Stevanovic, I1
Bozic, ID1
Milosevic, A1
Janjic, MM1
Laketa, D1
Bjelobaba, I1
Lavrnja, I1
Savic, D1
Еlmahdy, MK1
Abdelaziz, RR1
Elmahdi, HS1
Suddek, GM1
Kim, J1
Sim, AY1
Barua, S1
Kim, JY1
Lee, JE2
Turan, I1
Ozacmak, HS1
Ozacmak, VH1
Barut, F1
Araslı, M1
Deng, J1
Tian, L1
Ma, X1
Fan, X3
Hou, F2
Liang, H2
Luo, Y1
McCurtain, JL1
Gilbertsen, AJ2
Evert, C1
Williams, BJ2
Hunter, RC1
Paulson, NB1
Dalluge, JJ1
Welchlin, CW1
Hughes, J1
Han, W1
Blackwell, TS1
Laguna, TA1
Liu, Z1
Jin, H1
Xiao, Y1
Yang, X2
Yan, J1
Kim, JM1
Cheon, SY1
Lee, JH1
Kim, SY1
Kam, EH1
Koo, BN1
Taksande, BG1
Gawande, DY1
Chopde, CT1
Umekar, MJ1
Kotagale, NR1
Dyuizen, IV1
Lamash, NE1
Li, WG1
Yu, Y1
Zhang, ZD1
Cao, H1
Xu, TL1
Gu, Y1
Zhang, C1
Bao, YX1
Liang, HP1
Satriano, J2
Paszcuk, AF1
Gadotti, VM1
Tibola, D1
Quintão, NL1
Rodrigues, AL1
Calixto, JB1
Santos, AR1
Horváth, G1
Kékesi, G1
Dobos, I1
Szikszay, M1
Klimscha, W1
Benedek, G1
Regunathan, S2
Feinstein, DL1
Reis, DJ2
Fairbanks, CA1
Schreiber, KL1
Brewer, KL1
Yu, CG1
Stone, LS1
Kitto, KF1
Nguyen, HO1
Grocholski, BM1
Shoeman, DW1
Kehl, LJ1
Yezierski, RP1
Wilcox, GL1

Reviews

2 reviews available for agmatine and Innate Inflammatory Response

ArticleYear
Agmatine: at the crossroads of the arginine pathways.
    Annals of the New York Academy of Sciences, 2003, Volume: 1009

    Topics: Agmatine; Animals; Arginine; Carboxy-Lyases; Humans; Inflammation; Nitric Oxide; Nitric Oxide Syntha

2003
Arginine pathways and the inflammatory response: interregulation of nitric oxide and polyamines: review article.
    Amino acids, 2004, Volume: 26, Issue:4

    Topics: Agmatine; Animals; Arginine; Inflammation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthas

2004

Other Studies

17 other studies available for agmatine and Innate Inflammatory Response

ArticleYear
Agmatine Mitigates Inflammation-Related Oxidative Stress in BV-2 Cells by Inducing a Pre-Adaptive Response.
    International journal of molecular sciences, 2022, Mar-24, Volume: 23, Issue:7

    Topics: Agmatine; Animals; Glutathione; Inflammation; Lipopolysaccharides; Mice; Microglia; NF-E2-Related Fa

2022
Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study.
    Autoimmunity, 2022, Volume: 55, Issue:8

    Topics: Agmatine; Animals; Anti-Asthmatic Agents; Beclomethasone; Cytokines; Disease Models, Animal; Inflamm

2022
Agmatine-IRF2BP2 interaction induces M2 phenotype of microglia by increasing IRF2-KLF4 signaling.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2023, Volume: 72, Issue:6

    Topics: Agmatine; Carrier Proteins; DNA-Binding Proteins; Humans; Inflammation; Interferon Regulatory Factor

2023
Agmatine attenuates intestinal ischemia and reperfusion injury by reducing oxidative stress and inflammatory reaction in rats.
    Life sciences, 2017, Nov-15, Volume: 189

    Topics: Agmatine; Animals; Carbachol; Disease Models, Animal; Inflammation; Intestine, Small; Male; Malondia

2017
[The effects of agmatine on acute peritoneal inflammatory injury and neutrophil infiltration induced by zymosan in mice].
    Zhonghua wei zhong bing ji jiu yi xue, 2016, Volume: 28, Issue:3

    Topics: Agmatine; Animals; Chemokines; Cytokines; Inflammation; Interleukin-6; Male; Mice; Mice, Inbred C57B

2016
Agmatine accumulation by Pseudomonas aeruginosa clinical isolates confers antibiotic tolerance and dampens host inflammation.
    Journal of medical microbiology, 2019, Volume: 68, Issue:3

    Topics: Adaptation, Physiological; Agmatine; Animals; Anti-Bacterial Agents; Cystic Fibrosis; Disease Models

2019
The arginine decarboxylase pathways of host and pathogen interact to impact inflammatory pathways in the lung.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Agmatine; Animals; Biofilms; Carboxy-Lyases; Chromatography, High Pressure Liquid; Disease Models, A

2014
[Effects of agmatine on excessive inflammatory reaction and proliferation of splenic cells in mice with trauma].
    Zhonghua wei zhong bing ji jiu yi xue, 2015, Volume: 27, Issue:2

    Topics: Agmatine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Proliferation; Concanaval

2015
The Anti-inflammatory Effects of Agmatine on Transient Focal Cerebral Ischemia in Diabetic Rats.
    Journal of neurosurgical anesthesiology, 2016, Volume: 28, Issue:3

    Topics: Agmatine; Animals; Blotting, Western; Brain; Diabetes Mellitus, Experimental; Disease Models, Animal

2016
Agmatine ameliorates adjuvant induced arthritis and inflammatory cachexia in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 86

    Topics: Agmatine; Animals; Arthritis, Experimental; Body Weight; Cachexia; Inflammation; Male; Rats; Rats, S

2017
Effects of NO-modulating agents on the development of acute painful reaction in rats.
    Bulletin of experimental biology and medicine, 2008, Volume: 146, Issue:2

    Topics: Agmatine; Animals; Arginine; Behavior, Animal; Formaldehyde; Inflammation; Injections, Intraperitone

2008
ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domain.
    Molecular pain, 2010, Dec-08, Volume: 6

    Topics: Acid Sensing Ion Channels; Agmatine; Animals; Cells, Cultured; Inflammation; Ligands; Male; Nerve Ti

2010
[The protective effects of agmatine in zymosan induced acute lung injury in mice].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2011, Volume: 23, Issue:11

    Topics: Acute Lung Injury; Agmatine; Animals; Disease Models, Animal; Inflammation; Interleukin-6; Lung; Mal

2011
Anti-hypernociceptive properties of agmatine in persistent inflammatory and neuropathic models of pain in mice.
    Brain research, 2007, Jul-23, Volume: 1159

    Topics: Agmatine; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Cytokines; Disease Models, An

2007
Effect of intrathecal agmatine on inflammation-induced thermal hyperalgesia in rats.
    European journal of pharmacology, 1999, Mar-05, Volume: 368, Issue:2-3

    Topics: Agmatine; Analgesics, Opioid; Animals; Carrageenan; Dose-Response Relationship, Drug; Hindlimb; Hype

1999
Anti-proliferative and anti-inflammatory actions of imidazoline agents. Are imidazoline receptors involved?
    Annals of the New York Academy of Sciences, 1999, Jun-21, Volume: 881

    Topics: Agmatine; Animals; Animals, Newborn; Astrocytes; Cell Division; Cell Line; Cells, Cultured; Cerebral

1999
Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Sep-12, Volume: 97, Issue:19

    Topics: Agmatine; Analgesics; Animals; Immunohistochemistry; Inflammation; Male; Mice; N-Methylaspartate; Pa

2000