Page last updated: 2024-10-16

agmatine and Anxiety

agmatine has been researched along with Anxiety in 11 studies

Agmatine: Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Present study investigated the role of agmatine in ethanol-induced anxiolysis and withdrawal anxiety using elevated plus maze (EPM) test in rats."7.76Agmatine, an endogenous imidazoline receptor ligand modulates ethanol anxiolysis and withdrawal anxiety in rats. ( Chopde, CT; Kotagale, NR; Patel, MR; Shelkar, GP; Taksande, BG; Ugale, RR, 2010)
"Agmatine was administered intraperitoneally at the doses of 10, 20, 30, 40 and 80 mg/kg/daily to adult male NMRI mice for 10 days after which the behavioral assessments were performed."5.72The effects of subchronic agmatine on passive avoidance memory, anxiety-like behavior and hippocampal Akt/GSK-3β in mice. ( Amiri, Z; Esmaili, Z; Moezi, L; Moosavi, M; Ostovan, VR; Pirsalami, F, 2022)
"Agmatine levels were significantly reduced in the hippocampus of T2DM rats as compared to the normal fed (NF) control animals."5.56Agmatine modulates anxiety and depression-like behaviour in diabetic insulin-resistant rats. ( Aglawe, MM; Kale, M; Kotagale, N; Nimje, N; Taksande, B; Umekar, M, 2020)
"Present study investigated the role of agmatine in ethanol-induced anxiolysis and withdrawal anxiety using elevated plus maze (EPM) test in rats."3.76Agmatine, an endogenous imidazoline receptor ligand modulates ethanol anxiolysis and withdrawal anxiety in rats. ( Chopde, CT; Kotagale, NR; Patel, MR; Shelkar, GP; Taksande, BG; Ugale, RR, 2010)
"Agmatine is an endogenous polyamine produced from l-arginine and degraded by agmatinase (AGMAT)."1.91The expression of agmatinase manipulates the affective state of rats subjected to chronic restraint stress. ( Bai, S; Cai, X; Cheng, Y; He, Z; Tong, Z; Wang, G; Wang, T; Wu, J; Xu, C; Xue, Z; Yan, S; Yang, M; Zhang, H, 2023)
"Agmatine (37."1.91Preventive putative effect of agmatine on cognitive and molecular outcomes in ventral tegmental area of male offspring following physical and psychological prenatal stress. ( Behzadi, G; Hassanshahi, A; Hosseinmardi, N; Ilaghi, M; Janahmadi, M; Kohlmeier, KA; Ranjbar, H; Razavinasab, M; Shabani, M, 2023)
"Agmatine was administered intraperitoneally at the doses of 10, 20, 30, 40 and 80 mg/kg/daily to adult male NMRI mice for 10 days after which the behavioral assessments were performed."1.72The effects of subchronic agmatine on passive avoidance memory, anxiety-like behavior and hippocampal Akt/GSK-3β in mice. ( Amiri, Z; Esmaili, Z; Moezi, L; Moosavi, M; Ostovan, VR; Pirsalami, F, 2022)
"Agmatine levels were significantly reduced in the hippocampus of T2DM rats as compared to the normal fed (NF) control animals."1.56Agmatine modulates anxiety and depression-like behaviour in diabetic insulin-resistant rats. ( Aglawe, MM; Kale, M; Kotagale, N; Nimje, N; Taksande, B; Umekar, M, 2020)
"Agmatine is an endogenous released polyamine recently proposed to be a putative neurotransmitter, however its physiological role is still to be determined."1.32Agmatine induces anxiolysis in the elevated plus maze task in adult rats. ( Arteni, NS; Lavinsky, D; Netto, CA, 2003)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's4 (36.36)24.3611
2020's5 (45.45)2.80

Authors

AuthorsStudies
Ostovan, VR1
Amiri, Z1
Moezi, L1
Pirsalami, F1
Esmaili, Z1
Moosavi, M1
Yan, S1
Xu, C1
Yang, M1
Zhang, H1
Cheng, Y1
Xue, Z1
He, Z1
Wang, T1
Bai, S1
Wang, G1
Wu, J1
Tong, Z1
Cai, X1
Hassanshahi, A1
Janahmadi, M1
Razavinasab, M1
Ranjbar, H1
Hosseinmardi, N1
Behzadi, G1
Kohlmeier, KA1
Ilaghi, M1
Shabani, M1
Ozden, A1
Angelos, H1
Feyza, A1
Elizabeth, W1
John, P1
Kale, M1
Nimje, N1
Aglawe, MM1
Umekar, M1
Taksande, B1
Kotagale, N1
Taksande, BG3
Kotagale, NR3
Gawande, DY1
Bharne, AP1
Chopde, CT3
Kokare, DM1
Umekar, MJ1
Gawali, NB1
Bulani, VD1
Gursahani, MS1
Deshpande, PS1
Kothavade, PS1
Juvekar, AR1
Patel, MR1
Shelkar, GP1
Ugale, RR1
Lavinsky, D1
Arteni, NS1
Netto, CA1
Aricioglu, F1
Altunbas, H1

Other Studies

11 other studies available for agmatine and Anxiety

ArticleYear
The effects of subchronic agmatine on passive avoidance memory, anxiety-like behavior and hippocampal Akt/GSK-3β in mice.
    Behavioural pharmacology, 2022, 02-01, Volume: 33, Issue:1

    Topics: Agmatine; Alzheimer Disease; Animals; Anxiety; Avoidance Learning; Behavior, Animal; Biological Fact

2022
The expression of agmatinase manipulates the affective state of rats subjected to chronic restraint stress.
    Neuropharmacology, 2023, 05-15, Volume: 229

    Topics: Agmatine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Depression; Hippocampus; Hum

2023
Preventive putative effect of agmatine on cognitive and molecular outcomes in ventral tegmental area of male offspring following physical and psychological prenatal stress.
    Developmental psychobiology, 2023, Volume: 65, Issue:6

    Topics: Agmatine; Animals; Anxiety; Anxiety Disorders; Cognition; Female; Male; Mice; Pregnancy; Ventral Teg

2023
Altered plasma levels of arginine metabolites in depression.
    Journal of psychiatric research, 2020, Volume: 120

    Topics: Adult; Aged; Agmatine; Anxiety; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Depressi

2020
Agmatine modulates anxiety and depression-like behaviour in diabetic insulin-resistant rats.
    Brain research, 2020, 11-15, Volume: 1747

    Topics: Agmatine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Cytokines;

2020
Neuropeptide Y in the central nucleus of amygdala regulates the anxiolytic effect of agmatine in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:6

    Topics: Agmatine; Animals; Anti-Anxiety Agents; Anxiety; Arginine; Cell Count; Central Amygdaloid Nucleus; I

2014
Chronic agmatine treatment prevents behavioral manifestations of nicotine withdrawal in mice.
    European journal of pharmacology, 2015, May-05, Volume: 754

    Topics: Agmatine; Animals; Anxiety; Behavior, Animal; Brain; Depression; Infusions, Intraventricular; Male;

2015
Agmatine attenuates chronic unpredictable mild stress-induced anxiety, depression-like behaviours and cognitive impairment by modulating nitrergic signalling pathway.
    Brain research, 2017, 05-15, Volume: 1663

    Topics: Agmatine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Chronic Di

2017
Agmatine, an endogenous imidazoline receptor ligand modulates ethanol anxiolysis and withdrawal anxiety in rats.
    European journal of pharmacology, 2010, Jul-10, Volume: 637, Issue:1-3

    Topics: Agmatine; Animals; Anti-Anxiety Agents; Anxiety; Arginine; Biguanides; Brain; Clonidine; Dose-Respon

2010
Agmatine induces anxiolysis in the elevated plus maze task in adult rats.
    Behavioural brain research, 2003, Apr-17, Volume: 141, Issue:1

    Topics: Agmatine; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug

2003
Is agmatine an endogenous anxiolytic/antidepressant agent?
    Annals of the New York Academy of Sciences, 2003, Volume: 1009

    Topics: Agmatine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression

2003