agmatine has been researched along with Alloxan Diabetes in 15 studies
Agmatine: Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "L-Arginine supplementation prevented the development of mechanical hyperalgesia, tactile, and thermal allodynia in painful diabetic neuropathy with concomitant reduction of NO and increased agmatine production, offering new therapeutic opportunities for the management of diabetic neuropathic pain." | 7.88 | L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration. ( Courteix, C; Davin, N; Eschalier, A; Farges, MC; Privat, AM; Rondón, LJ; Sion, B; Vasson, MP, 2018) |
| "Agmatine levels were significantly reduced in the hippocampus of T2DM rats as compared to the normal fed (NF) control animals." | 5.56 | Agmatine modulates anxiety and depression-like behaviour in diabetic insulin-resistant rats. ( Aglawe, MM; Kale, M; Kotagale, N; Nimje, N; Taksande, B; Umekar, M, 2020) |
| "L-Arginine supplementation prevented the development of mechanical hyperalgesia, tactile, and thermal allodynia in painful diabetic neuropathy with concomitant reduction of NO and increased agmatine production, offering new therapeutic opportunities for the management of diabetic neuropathic pain." | 3.88 | L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration. ( Courteix, C; Davin, N; Eschalier, A; Farges, MC; Privat, AM; Rondón, LJ; Sion, B; Vasson, MP, 2018) |
| "Agmatine, an endogenous ligand of imidazoline receptors, was employed to screen the effect on insulin resistance in rats induced by a diet containing 60% fructose." | 3.74 | Activation of I(2)-imidazoline receptors may ameliorate insulin resistance in fructose-rich chow-fed rats. ( Cheng, JT; Chung, HH; Ko, WC; Liu, IM, 2008) |
| "Agmatine, an endogenous cationic amine resulting from the decarboxylation of L-arginine, produces antihyperalgesic and antiallodynic effects in animal models of chronic neuropathic and inflammatory pain." | 3.74 | Agmatine induces antihyperalgesic effects in diabetic rats and a superadditive interaction with R(-)-3-(2-carboxypiperazine-4-yl)-propyl-1-phosphonic acid, a N-methyl-D-aspartate-receptor antagonist. ( Courteix, C; Eschalier, A; Fialip, J; Hernandez, A; Pélissier, T; Privat, AM, 2007) |
| "Agmatine levels were significantly reduced in the hippocampus of T2DM rats as compared to the normal fed (NF) control animals." | 1.56 | Agmatine modulates anxiety and depression-like behaviour in diabetic insulin-resistant rats. ( Aglawe, MM; Kale, M; Kotagale, N; Nimje, N; Taksande, B; Umekar, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, YS | 1 |
| Song, JE | 1 |
| Kim, E | 1 |
| Kim, CH | 1 |
| Lee, JE | 3 |
| Song, HT | 1 |
| Kale, M | 1 |
| Nimje, N | 1 |
| Aglawe, MM | 1 |
| Umekar, M | 1 |
| Taksande, B | 1 |
| Kotagale, N | 1 |
| Abo El Gheit, RE | 1 |
| Soliman, NA | 1 |
| Badawi, GA | 1 |
| Madi, NM | 1 |
| El-Saka, MH | 1 |
| Badr, SM | 1 |
| Emam, MN | 1 |
| Rondón, LJ | 1 |
| Farges, MC | 1 |
| Davin, N | 1 |
| Sion, B | 1 |
| Privat, AM | 2 |
| Vasson, MP | 1 |
| Eschalier, A | 2 |
| Courteix, C | 2 |
| Ferents, IV | 1 |
| Brodiak, IV | 1 |
| Liuta, MIa | 1 |
| Kulachkovs'kyĭ, OR | 1 |
| Sybirna, NO | 1 |
| Kim, JM | 1 |
| Cheon, SY | 1 |
| Lee, JH | 2 |
| Kim, SY | 1 |
| Kam, EH | 1 |
| Koo, BN | 2 |
| Ko, WC | 1 |
| Liu, IM | 3 |
| Chung, HH | 1 |
| Cheng, JT | 4 |
| Chang, CH | 1 |
| Wu, HT | 1 |
| Cheng, KC | 1 |
| Lin, HJ | 1 |
| Cui, H | 1 |
| Kim, JY | 1 |
| Bhutada, P | 1 |
| Mundhada, Y | 1 |
| Humane, V | 1 |
| Rahigude, A | 1 |
| Deshmukh, P | 1 |
| Latad, S | 1 |
| Jain, K | 1 |
| Ozyazgan, S | 1 |
| Bicakci, B | 1 |
| Ozaydin, A | 1 |
| Denizbasi, A | 1 |
| Unluer, EE | 1 |
| Akkan, AG | 1 |
| Jou, SB | 1 |
| Hwang, SL | 1 |
| Tzeng, TF | 1 |
| Pélissier, T | 1 |
| Hernandez, A | 1 |
| Fialip, J | 1 |
| Marx, M | 1 |
| Trittenwein, G | 1 |
| Aufricht, C | 1 |
| Hoeger, H | 1 |
| Lubec, B | 1 |
15 other studies available for agmatine and Alloxan Diabetes
| Article | Year |
|---|---|
Hyperpolarized [1-
Topics: Agmatine; Animals; Brain; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Lactic Acid; M | 2023 |
Agmatine modulates anxiety and depression-like behaviour in diabetic insulin-resistant rats.
Topics: Agmatine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Cytokines; | 2020 |
Retinoprotective effect of agmatine in streptozotocin-induced diabetic rat model: avenues for vascular and neuronal protection : Agmatine in diabetic retinopathy.
Topics: Agmatine; Animals; Antioxidants; Blood Glucose; Caspase 3; Diabetes Mellitus, Experimental; Diabetic | 2021 |
L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration.
Topics: Administration, Oral; Agmatine; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Neuropa | 2018 |
[Effects of decarboxylated L-arginine on morphofunctional characteristics of the erythron in experimental diabetes mellitus in rats].
Topics: Agmatine; Animals; Blood Glucose; Decarboxylation; Diabetes Mellitus, Experimental; Erythrocyte Coun | 2014 |
The Anti-inflammatory Effects of Agmatine on Transient Focal Cerebral Ischemia in Diabetic Rats.
Topics: Agmatine; Animals; Blotting, Western; Brain; Diabetes Mellitus, Experimental; Disease Models, Animal | 2016 |
Activation of I(2)-imidazoline receptors may ameliorate insulin resistance in fructose-rich chow-fed rats.
Topics: Agmatine; Analysis of Variance; Animals; Area Under Curve; Behavior, Animal; Blood Glucose; Blood Pr | 2008 |
Increase of beta-endorphin secretion by agmatine is induced by activation of imidazoline I(2A) receptors in adrenal gland of rats.
Topics: Adrenal Glands; Adrenal Medulla; Agmatine; Amiloride; Animals; beta-Endorphin; Blood Glucose; Diabet | 2010 |
The neuroprotective effect of agmatine after focal cerebral ischemia in diabetic rats.
Topics: Agmatine; Animals; Apoptosis; Blood Glucose; Blotting, Western; Body Weight; Brain Edema; Cerebrovas | 2012 |
Agmatine, an endogenous ligand of imidazoline receptor protects against memory impairment and biochemical alterations in streptozotocin-induced diabetic rats.
Topics: Agmatine; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Imidazoline Re | 2012 |
The effect of agmatine on the vascular reactivity in streptozotocin-diabetic rats.
Topics: Acetylcholine; Agmatine; Analysis of Variance; Animals; Aorta; Blood Glucose; Body Weight; Diabetes | 2003 |
Activation of imidazoline receptor by agmatine to lower plasma glucose in streptozotocin-induced diabetic rats.
Topics: Agmatine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; | 2004 |
Activation of imidazoline receptors in adrenal gland to lower plasma glucose in streptozotocin-induced diabetic rats.
Topics: Adrenal Glands; Adrenal Medulla; Adrenalectomy; Agmatine; Animals; beta-Endorphin; Blood Glucose; Bl | 2005 |
Agmatine induces antihyperalgesic effects in diabetic rats and a superadditive interaction with R(-)-3-(2-carboxypiperazine-4-yl)-propyl-1-phosphonic acid, a N-methyl-D-aspartate-receptor antagonist.
Topics: Agmatine; Animals; Anticonvulsants; Diabetes Mellitus, Experimental; Drug Interactions; Excitatory A | 2007 |
Agmatine and spermidine reduce collagen accumulation in kidneys of diabetic db/db mice.
Topics: Agmatine; Animals; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, Experimental; Guanidines | 1995 |