agmatine has been researched along with Allodynia in 8 studies
Agmatine: Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "L-Arginine supplementation prevented the development of mechanical hyperalgesia, tactile, and thermal allodynia in painful diabetic neuropathy with concomitant reduction of NO and increased agmatine production, offering new therapeutic opportunities for the management of diabetic neuropathic pain." | 7.88 | L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration. ( Courteix, C; Davin, N; Eschalier, A; Farges, MC; Privat, AM; Rondón, LJ; Sion, B; Vasson, MP, 2018) |
| "Agmatine is an endogenous neuromodulator that has been previously implicated in the regulation of reward and pain processing." | 5.91 | Agmatine reduces alcohol drinking and produces antinociceptive effects in rodent models of alcohol use disorder. ( Becker, HC; Cucinello-Ragland, JA; Davis, EC; Edwards, S; Lopez, MF; Regunathan, S, 2023) |
| "Agmatine is an endogenous neuromodulator that has been shown to exert antiallodynic effects in various animal studies." | 5.48 | Agmatine co-treatment attenuates allodynia and structural abnormalities in cisplatin-induced neuropathy in rats. ( Aydin, S; Cengelli Unel, C; Donertas, B; Erol, K; Kaygisiz, B; Ozatik, O; Ulupinar, E; Yildirim, E, 2018) |
| "Agmatine pretreatment was found to dose-dependently attenuate the thermal hyperalgesia induced by intraplantar carrageenan." | 5.30 | Effect of intrathecal agmatine on inflammation-induced thermal hyperalgesia in rats. ( Benedek, G; Dobos, I; Horváth, G; Kékesi, G; Klimscha, W; Szikszay, M, 1999) |
| "L-Arginine supplementation prevented the development of mechanical hyperalgesia, tactile, and thermal allodynia in painful diabetic neuropathy with concomitant reduction of NO and increased agmatine production, offering new therapeutic opportunities for the management of diabetic neuropathic pain." | 3.88 | L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration. ( Courteix, C; Davin, N; Eschalier, A; Farges, MC; Privat, AM; Rondón, LJ; Sion, B; Vasson, MP, 2018) |
| "Agmatine, an endogenous cationic amine resulting from the decarboxylation of L-arginine, produces antihyperalgesic and antiallodynic effects in animal models of chronic neuropathic and inflammatory pain." | 3.74 | Agmatine induces antihyperalgesic effects in diabetic rats and a superadditive interaction with R(-)-3-(2-carboxypiperazine-4-yl)-propyl-1-phosphonic acid, a N-methyl-D-aspartate-receptor antagonist. ( Courteix, C; Eschalier, A; Fialip, J; Hernandez, A; Pélissier, T; Privat, AM, 2007) |
| "Agmatine is an endogenous neuromodulator that has been previously implicated in the regulation of reward and pain processing." | 1.91 | Agmatine reduces alcohol drinking and produces antinociceptive effects in rodent models of alcohol use disorder. ( Becker, HC; Cucinello-Ragland, JA; Davis, EC; Edwards, S; Lopez, MF; Regunathan, S, 2023) |
| "Agmatine is an endogenous neuromodulator that has been shown to exert antiallodynic effects in various animal studies." | 1.48 | Agmatine co-treatment attenuates allodynia and structural abnormalities in cisplatin-induced neuropathy in rats. ( Aydin, S; Cengelli Unel, C; Donertas, B; Erol, K; Kaygisiz, B; Ozatik, O; Ulupinar, E; Yildirim, E, 2018) |
| "Agmatine is an endogenous decarboxylation product of arginine that has been previously shown to antagonize the N-methyl-d-aspartate (NMDA) receptor and inhibit nitric-oxide synthase." | 1.33 | Pharmacodynamic and pharmacokinetic studies of agmatine after spinal administration in the mouse. ( Fairbanks, CA; Grocholski, BM; Kitto, KF; Roberts, JC, 2005) |
| "Kynurenic acid alone was ineffective, while adenosine and agmatine alone caused a slight increase in pain threshold." | 1.32 | Dose-independent antinociceptive interaction of endogenous ligands at the spinal level. ( Benedek, G; Csullog, E; Horvath, G; Joo, G; Kekesi, G; Peter-Szabo, M, 2004) |
| "Agmatine pretreatment was found to dose-dependently attenuate the thermal hyperalgesia induced by intraplantar carrageenan." | 1.30 | Effect of intrathecal agmatine on inflammation-induced thermal hyperalgesia in rats. ( Benedek, G; Dobos, I; Horváth, G; Kékesi, G; Klimscha, W; Szikszay, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Lopez, MF | 1 |
| Davis, EC | 1 |
| Cucinello-Ragland, JA | 1 |
| Regunathan, S | 1 |
| Edwards, S | 1 |
| Becker, HC | 1 |
| Rondón, LJ | 1 |
| Farges, MC | 1 |
| Davin, N | 1 |
| Sion, B | 1 |
| Privat, AM | 2 |
| Vasson, MP | 1 |
| Eschalier, A | 2 |
| Courteix, C | 2 |
| Donertas, B | 1 |
| Cengelli Unel, C | 1 |
| Aydin, S | 1 |
| Ulupinar, E | 1 |
| Ozatik, O | 1 |
| Kaygisiz, B | 1 |
| Yildirim, E | 1 |
| Erol, K | 1 |
| Kekesi, G | 2 |
| Joo, G | 1 |
| Csullog, E | 1 |
| Peter-Szabo, M | 1 |
| Benedek, G | 2 |
| Horvath, G | 2 |
| Roberts, JC | 1 |
| Grocholski, BM | 1 |
| Kitto, KF | 1 |
| Fairbanks, CA | 1 |
| Dogrul, A | 1 |
| Coskun, I | 1 |
| Uzbay, T | 1 |
| Pélissier, T | 1 |
| Hernandez, A | 1 |
| Fialip, J | 1 |
| Dobos, I | 1 |
| Szikszay, M | 1 |
| Klimscha, W | 1 |
8 other studies available for agmatine and Allodynia
| Article | Year |
|---|---|
Agmatine reduces alcohol drinking and produces antinociceptive effects in rodent models of alcohol use disorder.
Topics: Agmatine; Alcohol Drinking; Alcoholism; Analgesics; Animals; Ethanol; Female; Hyperalgesia; Male; Mi | 2023 |
L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration.
Topics: Administration, Oral; Agmatine; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Neuropa | 2018 |
Agmatine co-treatment attenuates allodynia and structural abnormalities in cisplatin-induced neuropathy in rats.
Topics: Agmatine; Analgesics; Animals; Animals, Newborn; Behavior, Animal; Cells, Cultured; Cisplatin; Disea | 2018 |
Dose-independent antinociceptive interaction of endogenous ligands at the spinal level.
Topics: Adenosine; Agmatine; Analgesics; Animals; Carrageenan; Dose-Response Relationship, Drug; Drug Combin | 2004 |
Pharmacodynamic and pharmacokinetic studies of agmatine after spinal administration in the mouse.
Topics: Agmatine; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hyperalgesia; Indazoles; I | 2005 |
The contribution of alpha-1 and alpha-2 adrenoceptors in peripheral imidazoline and adrenoceptor agonist-induced nociception.
Topics: Adrenergic alpha-Agonists; Agmatine; Analgesics; Animals; Clonidine; Dose-Response Relationship, Dru | 2006 |
Agmatine induces antihyperalgesic effects in diabetic rats and a superadditive interaction with R(-)-3-(2-carboxypiperazine-4-yl)-propyl-1-phosphonic acid, a N-methyl-D-aspartate-receptor antagonist.
Topics: Agmatine; Animals; Anticonvulsants; Diabetes Mellitus, Experimental; Drug Interactions; Excitatory A | 2007 |
Effect of intrathecal agmatine on inflammation-induced thermal hyperalgesia in rats.
Topics: Agmatine; Analgesics, Opioid; Animals; Carrageenan; Dose-Response Relationship, Drug; Hindlimb; Hype | 1999 |