agathisflavone has been researched along with Inflammation* in 2 studies
2 other study(ies) available for agathisflavone and Inflammation
| Article | Year |
|---|---|
Phytoestrogen Agathisflavone Ameliorates Neuroinflammation-Induced by LPS and IL-1β and Protects Neurons in Cocultures of Glia/Neurons.
Topics: Anti-Inflammatory Agents; Biflavonoids; Coculture Techniques; Humans; Inflammation; Interleukin-1beta; Lipopolysaccharides; Neuroglia; Neurons; Phytoestrogens | 2020 |
Agathisflavone isolated from Anacardium occidentale suppresses SIRT1-mediated neuroinflammation in BV2 microglia and neurotoxicity in APPSwe-transfected SH-SY5Y cells.
Agathisflavone is a bioactive compound in Anacardium occidentale. In this study, we investigated inhibition neuroinflammation in BV2 microglia by agathisflavone. Neuroprotective activity of the compound was investigated in differentiated SH-SY5Y cells. Experiments in lipopolysaccharide (LPS)-activated BV2 microglia showed that pretreatment with agathisflavone (5-20 μM) produced significant reduction in the release of tumour necrosis factor-α, interleukin-6, interleukin-1β, NO, and PGE Topics: Anacardium; Animals; Anti-Inflammatory Agents; Biflavonoids; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mice; Microglia; NF-kappa B; Nitric Oxide; Signal Transduction; Sirtuin 1; Tumor Necrosis Factor-alpha | 2018 |