agar and Soft-Tissue-Neoplasms

agar has been researched along with Soft-Tissue-Neoplasms* in 2 studies

Other Studies

2 other study(ies) available for agar and Soft-Tissue-Neoplasms

ArticleYear
MR validation of soft tissue mimicing phantom deformation as modeled by nonlinear finite element analysis.
    Medical physics, 2002, Volume: 29, Issue:1

    A study of the applicability of nonlinear finite element analysis (FEA) to predict soft tissue deformation was validated with phase contrast magnetic resonance velocity imaging. A phantom of varying stiffness was placed in a special purpose, computer controlled MR compatible compression apparatus which provided precise, time varying compression with surface deformations on the order of 11%. The resulting motion was measured with MR velocity images acquired throughout the cycle of compression. The phantom geometry was modeled with a finite element mesh and the mechanical properties of the phantom material were measured and incorporated in the FEA model. The motion as calculated by the FEA model was compared to the motion measured with MRI and the results were found to vary with the material's Poisson's ratio and the coefficient of friction. A minimum difference was reached when the Poisson's ratio and coefficient of friction were set to 0.485 and 0.3, respectively. Under these conditions, the root mean square difference was found to be 14.4%.

    Topics: Agar; Algorithms; Anisotropy; Gelatin; Humans; Magnetic Resonance Imaging; Models, Statistical; Phantoms, Imaging; Poisson Distribution; Soft Tissue Neoplasms; Time Factors

2002
Colony growth in soft agar of human melanoma, sarcoma, and lung carcinoma cells disaggregated by mechanical and enzymatic methods.
    Cancer research, 1980, Volume: 40, Issue:7

    The effect of mechanical and enzymatic disaggregation on human malignant melanoma, soft-tissue sarcoma and lung carcinoma colony growth in soft agar was studied. The enzymatic disaggregation was advantageous in most cases of melanoma and sarcoma, giving a larger number of colonies and increasing the probability of achieving growth in soft agar. Enzymatically treated pulmonary carcinoma cell populations had lower clonogeneic potential, especially in the case of anaplastic carcinomas. Morphological studies showed that the cells growing in soft-agar colonies had the same characteristics as those of the original tumor. A linear relationship was obtained between the number of enzymatically and mechanically treated tumor cells plated and the number of colonies. Delayed plating decreased the number of colonies.

    Topics: Agar; Carcinoma; Cell Aggregation; Clone Cells; Cytological Techniques; Humans; Lung Neoplasms; Melanoma; Microbial Collagenase; Sarcoma; Soft Tissue Neoplasms; Time Factors

1980