agar and Skin-Diseases--Bacterial

agar has been researched along with Skin-Diseases--Bacterial* in 2 studies

Other Studies

2 other study(ies) available for agar and Skin-Diseases--Bacterial

Article	Year
Incorporation of a Theranostic "Two-Tone" Luminescent Silver Complex into Biocompatible Agar Hydrogel Composite for the Eradication of ESKAPE Pathogens in a Skin and Soft Tissue Infection Model. Inorganic chemistry, 2018, Jun-04, Volume: 57, Issue:11 Topics: Agar; Anti-Bacterial Agents; Coordination Complexes; Drug Carriers; Drug Resistance, Multiple, Bacterial; Drug Stability; Fluorescent Dyes; Gram-Negative Aerobic Rods and Cocci; Hydrogels; Ligands; Microbial Sensitivity Tests; Prodrugs; Silver; Skin Diseases, Bacterial; Soft Tissue Infections; Staphylococcus aureus; Surgical Wound Infection; Theranostic Nanomedicine	2018
New insights on the antibacterial efficacy of miconazole in vitro. Mycoses, 2017, Volume: 60, Issue:8 Miconazole is a broad-spectrum antifungal used in topical preparations. In the present investigation the minimal inhibitory concentration (MIC) of miconazole for eighty wild type strains of gram-positive and gram-negative bacteria isolated from infected skin lesions was assessed using a modified agar dilution test (adapted to CLSI, Clinical Laboratory Standards Institute). 14 ATCC reference strains served as controls. Miconazole was found efficacious against gram-positive aerobic bacteria (n=62 species), the MICs against Staphylococcus (S.) aureus, S. spp., Streptococcus spp. und Enterococcus spp. ranged between 0.78 and 6.25 μg/mL. Interestingly, there were no differences in susceptibility between methicillin-susceptible (MSSA, 3) methicillin-resistant (MRSA, 6) and fusidic acid-resistant (FRSA, 2) S. aureus isolates. Strains of Streptococcus pyogenes (A-streptococci) (8) were found to be slightly more sensitive (0.78-1.563 μg/mL), while for gram-negative bacteria, no efficacy was found within the concentrations tested (MIC >200 μg/mL). In conclusion, for the gram-positive aerobic bacteria the MICs of miconazole were found within a range which is much lower than the concentration of miconazole used in topical preparations (2%). Thus topically applied miconazole might be a therapeutic option in skin infections especially caused by gram-positive bacteria even by those strains which are resistant to antibiotics. Topics: Agar; Anti-Bacterial Agents; Antifungal Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Indicator Dilution Techniques; Miconazole; Microbial Sensitivity Tests; Skin Diseases, Bacterial	2017

Article

Year

Incorporation of a Theranostic "Two-Tone" Luminescent Silver Complex into Biocompatible Agar Hydrogel Composite for the Eradication of ESKAPE Pathogens in a Skin and Soft Tissue Infection Model.

Inorganic chemistry, 2018, Jun-04, Volume: 57, Issue:11

Topics: Agar; Anti-Bacterial Agents; Coordination Complexes; Drug Carriers; Drug Resistance, Multiple, Bacterial; Drug Stability; Fluorescent Dyes; Gram-Negative Aerobic Rods and Cocci; Hydrogels; Ligands; Microbial Sensitivity Tests; Prodrugs; Silver; Skin Diseases, Bacterial; Soft Tissue Infections; Staphylococcus aureus; Surgical Wound Infection; Theranostic Nanomedicine

2018

New insights on the antibacterial efficacy of miconazole in vitro.

Mycoses, 2017, Volume: 60, Issue:8

Miconazole is a broad-spectrum antifungal used in topical preparations. In the present investigation the minimal inhibitory concentration (MIC) of miconazole for eighty wild type strains of gram-positive and gram-negative bacteria isolated from infected skin lesions was assessed using a modified agar dilution test (adapted to CLSI, Clinical Laboratory Standards Institute). 14 ATCC reference strains served as controls. Miconazole was found efficacious against gram-positive aerobic bacteria (n=62 species), the MICs against Staphylococcus (S.) aureus, S. spp., Streptococcus spp. und Enterococcus spp. ranged between 0.78 and 6.25 μg/mL. Interestingly, there were no differences in susceptibility between methicillin-susceptible (MSSA, 3) methicillin-resistant (MRSA, 6) and fusidic acid-resistant (FRSA, 2) S. aureus isolates. Strains of Streptococcus pyogenes (A-streptococci) (8) were found to be slightly more sensitive (0.78-1.563 μg/mL), while for gram-negative bacteria, no efficacy was found within the concentrations tested (MIC >200 μg/mL). In conclusion, for the gram-positive aerobic bacteria the MICs of miconazole were found within a range which is much lower than the concentration of miconazole used in topical preparations (2%). Thus topically applied miconazole might be a therapeutic option in skin infections especially caused by gram-positive bacteria even by those strains which are resistant to antibiotics.

Topics: Agar; Anti-Bacterial Agents; Antifungal Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Indicator Dilution Techniques; Miconazole; Microbial Sensitivity Tests; Skin Diseases, Bacterial

2017