ag-490 and Anemia

ag-490 has been researched along with Anemia* in 1 studies

Other Studies

1 other study(ies) available for ag-490 and Anemia

Article	Year
AG490: an inhibitor of hepcidin expression in vivo. World journal of gastroenterology, 2011, Dec-07, Volume: 17, Issue:45 A liver-produced hormone, hepcidin, appears to be the key player in iron metabolism. The overexpression of hepcidin is the underlying cause of anemia of inflammation. The identification of compounds inhibiting hepcidin expression could ameliorate anemia associated with inflammation. In the current study, we have demonstrated for the first time that AG490 significantly abolishes hepcidin expression in mice. Our work represents a novel approach to suppress hepcidin expression for treatment of anemia of inflammation and anemias occurring under other conditions. Topics: Anemia; Animals; Antimicrobial Cationic Peptides; Enzyme Inhibitors; Hepcidins; Homeostasis; Humans; Iron; Mice; Tyrphostins	2011

Article

Year

AG490: an inhibitor of hepcidin expression in vivo.

World journal of gastroenterology, 2011, Dec-07, Volume: 17, Issue:45

A liver-produced hormone, hepcidin, appears to be the key player in iron metabolism. The overexpression of hepcidin is the underlying cause of anemia of inflammation. The identification of compounds inhibiting hepcidin expression could ameliorate anemia associated with inflammation. In the current study, we have demonstrated for the first time that AG490 significantly abolishes hepcidin expression in mice. Our work represents a novel approach to suppress hepcidin expression for treatment of anemia of inflammation and anemias occurring under other conditions.

Topics: Anemia; Animals; Antimicrobial Cationic Peptides; Enzyme Inhibitors; Hepcidins; Homeostasis; Humans; Iron; Mice; Tyrphostins

2011