ag 1879 has been researched along with Prostatic Hyperplasia in 1 studies
3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor
Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "SFK inhibitors, AZM475271 and PP2, were applied to human prostate tissues to assess effects on smooth muscle contraction, and to cultured stromal (WPMY-1) and c-Src-deficient cells to examine effects on proliferation, actin organization and viability." | 7.83 | Smooth muscle contraction and growth of stromal cells in the human prostate are both inhibited by the Src family kinase inhibitors, AZM475271 and PP2. ( Ciotkowska, A; Gratzke, C; Hennenberg, M; Herlemann, A; Janich, S; Liu, C; Rutz, B; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R; Wang, Y, 2016) |
| "SFK inhibitors, AZM475271 and PP2, were applied to human prostate tissues to assess effects on smooth muscle contraction, and to cultured stromal (WPMY-1) and c-Src-deficient cells to examine effects on proliferation, actin organization and viability." | 3.83 | Smooth muscle contraction and growth of stromal cells in the human prostate are both inhibited by the Src family kinase inhibitors, AZM475271 and PP2. ( Ciotkowska, A; Gratzke, C; Hennenberg, M; Herlemann, A; Janich, S; Liu, C; Rutz, B; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R; Wang, Y, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Gratzke, C | 1 |
| Tamalunas, A | 1 |
| Rutz, B | 1 |
| Ciotkowska, A | 1 |
| Strittmatter, F | 1 |
| Herlemann, A | 1 |
| Janich, S | 1 |
| Waidelich, R | 1 |
| Liu, C | 1 |
| Stief, CG | 1 |
| Hennenberg, M | 1 |
1 other study available for ag 1879 and Prostatic Hyperplasia
| Article | Year |
|---|---|
Smooth muscle contraction and growth of stromal cells in the human prostate are both inhibited by the Src family kinase inhibitors, AZM475271 and PP2.
Topics: Blotting, Western; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Male; Muscle Contra | 2016 |