Page last updated: 2024-11-03

ag 1879 and Ovarian Neoplasms

ag 1879 has been researched along with Ovarian Neoplasms in 6 studies

3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor

Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.

Research Excerpts

ExcerptRelevanceReference
"Ovarian cancer is the leading cause of death from gynecologic malignancies in the United States."1.32Inhibitors that target protein kinases for the treatment of ovarian carcinoma. ( Arbel, R; Ben-Bassat, H; Hartzstark, Z; Klein, BY; Laufer, N; Levitzki, R; Rojansky, N, 2003)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kumar, A1
Ahmad, I1
Chhikara, BS1
Tiwari, R1
Mandal, D1
Parang, K1
Huang, RY1
Wang, SM1
Hsieh, CY1
Wu, JC1
Jeong, KJ1
Park, SY1
Seo, JH1
Lee, KB1
Choi, WS1
Han, JW1
Kang, JK1
Park, CG1
Kim, YK1
Lee, HY1
Arbel, R1
Rojansky, N1
Klein, BY1
Levitzki, R1
Hartzstark, Z1
Laufer, N1
Ben-Bassat, H1
Wakahara, K1
Kobayashi, H1
Yagyu, T1
Matsuzaki, H1
Kondo, T1
Kurita, N1
Sekino, H1
Inagaki, K1
Suzuki, M1
Kanayama, N1
Terao, T1
Chen, T1
Pengetnze, Y1
Taylor, CC1

Other Studies

6 other studies available for ag 1879 and Ovarian Neoplasms

ArticleYear
Synthesis of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates and evaluation of their Src kinase inhibitory and anticancer activities.
    Bioorganic & medicinal chemistry letters, 2011, Mar-01, Volume: 21, Issue:5

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Fe

2011
Lysophosphatidic acid induces ovarian cancer cell dispersal by activating Fyn kinase associated with p120-catenin.
    International journal of cancer, 2008, Aug-15, Volume: 123, Issue:4

    Topics: Adherens Junctions; alpha Catenin; Catenins; Cell Adhesion Molecules; Cell Line, Tumor; Delta Cateni

2008
Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells.
    Experimental & molecular medicine, 2008, Dec-31, Volume: 40, Issue:6

    Topics: Butadienes; Cell Line, Tumor; Cell Movement; CSK Tyrosine-Protein Kinase; Cyclooxygenase 2; ErbB Rec

2008
Inhibitors that target protein kinases for the treatment of ovarian carcinoma.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Catechols; Cell Cycle; Cell Division; Dose-Response Rel

2003
Transforming growth factor-beta1-dependent activation of Smad2/3 and up-regulation of PAI-1 expression is negatively regulated by Src in SKOV-3 human ovarian cancer cells.
    Journal of cellular biochemistry, 2004, Oct-15, Volume: 93, Issue:3

    Topics: DNA-Binding Proteins; Female; Flavonoids; Humans; Intracellular Signaling Peptides and Proteins; MAP

2004
Src inhibition enhances paclitaxel cytotoxicity in ovarian cancer cells by caspase-9-independent activation of caspase-3.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Caspase 3; Caspase 9; Caspases; Cisplatin; Cytochromes c

2005