ag 1879 has been researched along with Osteogenic Sarcoma in 3 studies
3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor
Excerpt | Relevance | Reference |
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"We show that the treatment of human osteosarcoma cell lines with a new pyrazolo[3,4-d]pyrimidine derivative Src inhibitor, namely SI-83, impaired cell viability, with a half-maximal inhibitory concentration of 12 microM in nonstarved cells and a kinetic different from that known for the Src inhibitor PP2." | 1.35 | Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells. ( Angelucci, A; Bernardini, G; Bologna, M; Botta, M; Collodel, G; Di Stefano, A; Magrini, D; Manetti, F; Orlandini, M; Santucci, A; Schenone, S; Serchi, T; Spreafico, A; Tintori, C, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Manetti, F | 2 |
Santucci, A | 2 |
Locatelli, GA | 1 |
Maga, G | 1 |
Spreafico, A | 2 |
Serchi, T | 2 |
Orlandini, M | 2 |
Bernardini, G | 2 |
Caradonna, NP | 1 |
Spallarossa, A | 1 |
Brullo, C | 1 |
Schenone, S | 2 |
Bruno, O | 1 |
Ranise, A | 1 |
Bondavalli, F | 1 |
Hoffmann, O | 1 |
Bologna, M | 2 |
Angelucci, A | 2 |
Botta, M | 2 |
Enomoto, M | 1 |
Hayakawa, S | 1 |
Itsukushima, S | 1 |
Ren, DY | 1 |
Matsuo, M | 1 |
Tamada, K | 1 |
Oneyama, C | 1 |
Okada, M | 1 |
Takumi, T | 1 |
Nishita, M | 1 |
Minami, Y | 1 |
Magrini, D | 1 |
Collodel, G | 1 |
Di Stefano, A | 1 |
Tintori, C | 1 |
3 other studies available for ag 1879 and Osteogenic Sarcoma
Article | Year |
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Identification of a novel pyrazolo[3,4-d]pyrimidine able to inhibit cell proliferation of a human osteogenic sarcoma in vitro and in a xenograft model in mice.
Topics: Animals; Bone Neoplasms; Bone Resorption; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Dru | 2007 |
Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling.
Topics: Cell Line, Tumor; Cell Movement; CSK Tyrosine-Protein Kinase; Enzyme Activation; Extracellular Matri | 2009 |
Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Male; Mice; Middle | 2008 |