ag 1879 has been researched along with Muscular Dystrophy, Duchenne in 1 studies
3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor
Muscular Dystrophy, Duchenne: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sanarica, F | 1 |
| Mantuano, P | 1 |
| Conte, E | 1 |
| Cozzoli, A | 1 |
| Capogrosso, RF | 1 |
| Giustino, A | 1 |
| Cutrignelli, A | 1 |
| Cappellari, O | 1 |
| Rolland, JF | 1 |
| De Bellis, M | 1 |
| Denora, N | 1 |
| Camerino, GM | 1 |
| De Luca, A | 1 |
1 other study available for ag 1879 and Muscular Dystrophy, Duchenne
| Article | Year |
|---|---|
Proof-of-concept validation of the mechanism of action of Src tyrosine kinase inhibitors in dystrophic mdx mouse muscle: in vivo and in vitro studies.
Topics: Animals; Cell Line; Cell Survival; Dasatinib; Dystroglycans; Liver; Male; Mice, Inbred mdx; Muscle F | 2019 |