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ag 1879 and Muscle Contraction

ag 1879 has been researched along with Muscle Contraction in 5 studies

3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"SFK inhibitors, AZM475271 and PP2, were applied to human prostate tissues to assess effects on smooth muscle contraction, and to cultured stromal (WPMY-1) and c-Src-deficient cells to examine effects on proliferation, actin organization and viability."7.83Smooth muscle contraction and growth of stromal cells in the human prostate are both inhibited by the Src family kinase inhibitors, AZM475271 and PP2. ( Ciotkowska, A; Gratzke, C; Hennenberg, M; Herlemann, A; Janich, S; Liu, C; Rutz, B; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R; Wang, Y, 2016)
"SFK inhibitors, AZM475271 and PP2, were applied to human prostate tissues to assess effects on smooth muscle contraction, and to cultured stromal (WPMY-1) and c-Src-deficient cells to examine effects on proliferation, actin organization and viability."3.83Smooth muscle contraction and growth of stromal cells in the human prostate are both inhibited by the Src family kinase inhibitors, AZM475271 and PP2. ( Ciotkowska, A; Gratzke, C; Hennenberg, M; Herlemann, A; Janich, S; Liu, C; Rutz, B; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R; Wang, Y, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saphirstein, RJ1
Gao, YZ1
Jensen, MH1
Gallant, CM2
Vetterkind, S2
Moore, JR1
Morgan, KG2
Wang, Y1
Gratzke, C1
Tamalunas, A1
Rutz, B1
Ciotkowska, A1
Strittmatter, F1
Herlemann, A1
Janich, S1
Waidelich, R1
Liu, C1
Stief, CG1
Hennenberg, M1
Min, J1
Reznichenko, M1
Poythress, RH1
Li, Y1
Kusaka, G1
Kimura, H1
Kusaka, I1
Perkins, E1
Nanda, A1
Zhang, JH1
Wright, DC1
Geiger, PC1
Han, DH1
Holloszy, JO1

Other Studies

5 other studies available for ag 1879 and Muscle Contraction

ArticleYear
The focal adhesion: a regulated component of aortic stiffness.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Animals; Aorta; Extracellular Matrix; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; In V

2013
Smooth muscle contraction and growth of stromal cells in the human prostate are both inhibited by the Src family kinase inhibitors, AZM475271 and PP2.
    British journal of pharmacology, 2016, Volume: 173, Issue:23

    Topics: Blotting, Western; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Male; Muscle Contra

2016
Src modulates contractile vascular smooth muscle function via regulation of focal adhesions.
    Journal of cellular physiology, 2012, Volume: 227, Issue:11

    Topics: Animals; Aorta; Ferrets; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Gene Knockdown Te

2012
Contribution of Src tyrosine kinase to cerebral vasospasm after subarachnoid hemorrhage.
    Journal of neurosurgery, 2003, Volume: 99, Issue:2

    Topics: Animals; Anthraquinones; Blotting, Western; Cerebral Angiography; Disease Models, Animal; Dogs; Fema

2003
Are tyrosine kinases involved in mediating contraction-stimulated muscle glucose transport?
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:1

    Topics: Animals; Benzoquinones; Biological Transport; Chalcone; Chalcones; Deoxyglucose; Electric Stimulatio

2006