Page last updated: 2024-11-03

ag 1879 and Melanoma

ag 1879 has been researched along with Melanoma in 3 studies

3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"Melanoma is one of the most deadly cancers because of its high propensity to metastasis, a process that requires migration and invasion of tumor cells driven by the regulated formation of adhesives structures like focal adhesions (FAs) and invasive structures like invadopodia."1.40FAK competes for Src to promote migration against invasion in melanoma cells. ( De Mey, J; Gies, JP; Kolli-Bouhafs, K; Noulet, F; Rondé, P; Sick, E, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ku, KE1
Choi, N1
Oh, SH1
Kim, WS1
Suh, W1
Sung, JH1
Kolli-Bouhafs, K1
Sick, E1
Noulet, F1
Gies, JP1
De Mey, J1
Rondé, P1
Liu, H1
Ong, SE1
Badu-Nkansah, K1
Schindler, J1
White, FM1
Hynes, RO1

Other Studies

3 other studies available for ag 1879 and Melanoma

ArticleYear
Src inhibition induces melanogenesis in human G361 cells.
    Molecular medicine reports, 2019, Volume: 19, Issue:4

    Topics: alpha-MSH; Biomarkers; Cell Line, Tumor; Cell Transformation, Neoplastic; Cyclic AMP Response Elemen

2019
FAK competes for Src to promote migration against invasion in melanoma cells.
    Cell death & disease, 2014, Aug-14, Volume: 5

    Topics: Animals; Cell Line, Tumor; Cell Movement; Focal Adhesion Kinase 1; Melanoma; Metalloporphyrins; Mice

2014
CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Jan-25, Volume: 108, Issue:4

    Topics: Animals; Antigens, CD; Antigens, Neoplasm; Blotting, Western; Cell Adhesion; Cell Adhesion Molecules

2011