ag 1879 has been researched along with Melanoma in 3 studies
3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melanoma is one of the most deadly cancers because of its high propensity to metastasis, a process that requires migration and invasion of tumor cells driven by the regulated formation of adhesives structures like focal adhesions (FAs) and invasive structures like invadopodia." | 1.40 | FAK competes for Src to promote migration against invasion in melanoma cells. ( De Mey, J; Gies, JP; Kolli-Bouhafs, K; Noulet, F; Rondé, P; Sick, E, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ku, KE | 1 |
| Choi, N | 1 |
| Oh, SH | 1 |
| Kim, WS | 1 |
| Suh, W | 1 |
| Sung, JH | 1 |
| Kolli-Bouhafs, K | 1 |
| Sick, E | 1 |
| Noulet, F | 1 |
| Gies, JP | 1 |
| De Mey, J | 1 |
| Rondé, P | 1 |
| Liu, H | 1 |
| Ong, SE | 1 |
| Badu-Nkansah, K | 1 |
| Schindler, J | 1 |
| White, FM | 1 |
| Hynes, RO | 1 |
3 other studies available for ag 1879 and Melanoma
| Article | Year |
|---|---|
Src inhibition induces melanogenesis in human G361 cells.
Topics: alpha-MSH; Biomarkers; Cell Line, Tumor; Cell Transformation, Neoplastic; Cyclic AMP Response Elemen | 2019 |
FAK competes for Src to promote migration against invasion in melanoma cells.
Topics: Animals; Cell Line, Tumor; Cell Movement; Focal Adhesion Kinase 1; Melanoma; Metalloporphyrins; Mice | 2014 |
CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.
Topics: Animals; Antigens, CD; Antigens, Neoplasm; Blotting, Western; Cell Adhesion; Cell Adhesion Molecules | 2011 |