ag 1879 has been researched along with Leukemia, Promyelocytic, Acute in 3 studies
3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor
Leukemia, Promyelocytic, Acute: An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO) combination yields high-quality remission and survival in newly-diagnosed acute promyelocytic leukemia (APL)." | 7.80 | Src family kinase inhibitor PP2 enhances differentiation of acute promyelocytic leukemia cell line induced by combination of all-trans-retinoic acid and arsenic trioxide. ( Cheong, HJ; Jung, YS; Kim, KH; Kim, SJ; Lee, N; Park, HS; Won, JH, 2014) |
| "An all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO) combination yields high-quality remission and survival in newly-diagnosed acute promyelocytic leukemia (APL)." | 3.80 | Src family kinase inhibitor PP2 enhances differentiation of acute promyelocytic leukemia cell line induced by combination of all-trans-retinoic acid and arsenic trioxide. ( Cheong, HJ; Jung, YS; Kim, KH; Kim, SJ; Lee, N; Park, HS; Won, JH, 2014) |
| "While acute promyelocytic leukemia (APL) patients are highly responsive to retinoic acid (RA) therapy, kinase inhibitors have been gaining momentum as co-treatments with RA for non-APL acute myeloid leukemia (AML) differentiation therapies, especially as a means to treat relapsed or refractory AML patients." | 1.42 | GW5074 and PP2 kinase inhibitors implicate nontraditional c-Raf and Lyn function as drivers of retinoic acid-induced maturation. ( Bunaciu, RP; Jensen, HA; Varner, JD; Yen, A, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jung, YS | 1 |
| Cheong, HJ | 1 |
| Kim, SJ | 1 |
| Kim, KH | 1 |
| Lee, N | 1 |
| Park, HS | 1 |
| Won, JH | 1 |
| Jensen, HA | 1 |
| Bunaciu, RP | 1 |
| Varner, JD | 1 |
| Yen, A | 1 |
| Jones, JE | 1 |
| Wang, L | 1 |
| Kropf, PL | 1 |
| Duan, R | 1 |
| Johnson, DE | 1 |
3 other studies available for ag 1879 and Leukemia, Promyelocytic, Acute
| Article | Year |
|---|---|
Src family kinase inhibitor PP2 enhances differentiation of acute promyelocytic leukemia cell line induced by combination of all-trans-retinoic acid and arsenic trioxide.
Topics: Apoptosis; Arsenic Trioxide; Arsenicals; CD11b Antigen; Cell Differentiation; Cell Line, Tumor; Drug | 2014 |
GW5074 and PP2 kinase inhibitors implicate nontraditional c-Raf and Lyn function as drivers of retinoic acid-induced maturation.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; CD11b Antigen; Cell Different | 2015 |
Src family kinase gene targets during myeloid differentiation: identification of the EGR-1 gene as a direct target.
Topics: Antineoplastic Agents; Cell Differentiation; Early Growth Response Protein 1; Gene Expression Profil | 2009 |