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ag 1879 and Inflammation

ag 1879 has been researched along with Inflammation in 13 studies

3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"After measures of mechanical allodynia returned to baseline, vehicle or the SFK inhibitor PP2 were injected intrathecally."1.56A Src family kinase maintains latent sensitization in rats, a model of inflammatory and neuropathic pain. ( Chen, W; Marvizón, JC, 2020)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's6 (46.15)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Manolache, A1
Selescu, T1
Maier, GL1
Mentel, M1
Ionescu, AE1
Neacsu, C1
Babes, A1
Szedlacsek, SE1
Chen, W1
Marvizón, JC1
Fiorotto, R1
Amenduni, M1
Mariotti, V1
Fabris, L1
Spirli, C1
Strazzabosco, M1
Behnen, M1
Leschczyk, C1
Möller, S1
Batel, T1
Klinger, M1
Solbach, W1
Laskay, T1
Luo, T1
Hu, J1
Xi, D1
Xiong, H1
He, W1
Liu, J1
Li, M1
Lu, H1
Zhao, J1
Lai, W1
Guo, Z1
Reddy, MA1
Sahar, S1
Villeneuve, LM1
Lanting, L1
Natarajan, R1
Sciullo, EM1
Dong, B1
Vogel, CF1
Matsumura, F1
Xia, YC1
Harris, T1
Stewart, AG1
Mackay, GA1
Xu, L1
Pan, Y1
Zhu, Q1
Gong, S1
Tao, J1
Xu, GY1
Jiang, X1
Vittal, R1
Horowitz, JC1
Moore, BB1
Zhang, H1
Martinez, FJ1
Toews, GB1
Standiford, TJ1
Thannickal, VJ1
Fulton, D1
Church, JE1
Ruan, L1
Li, C1
Sood, SG1
Kemp, BE1
Jennings, IG1
Venema, RC1
Wang, YY1
Myhre, AE1
Pettersen, SJ1
Dahle, MK1
Foster, SJ1
Thiemermann, C1
Bjørnland, K1
Aasen, AO1
Wang, JE1

Other Studies

13 other studies available for ag 1879 and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Regulation of TRPM8 channel activity by Src-mediated tyrosine phosphorylation.
    Journal of cellular physiology, 2020, Volume: 235, Issue:6

    Topics: Animals; Biological Transport; Cold Temperature; Ganglia, Spinal; HEK293 Cells; Humans; Inflammation

2020
A Src family kinase maintains latent sensitization in rats, a model of inflammatory and neuropathic pain.
    Brain research, 2020, 11-01, Volume: 1746

    Topics: Animals; Central Nervous System Sensitization; Disease Models, Animal; Hyperalgesia; Inflammation; M

2020
Src kinase inhibition reduces inflammatory and cytoskeletal changes in ΔF508 human cholangiocytes and improves cystic fibrosis transmembrane conductance regulator correctors efficacy.
    Hepatology (Baltimore, Md.), 2018, Volume: 67, Issue:3

    Topics: Aminophenols; Aminopyridines; Animals; Benzodioxoles; Biliary Tract; Cell Culture Techniques; Chlori

2018
Immobilized immune complexes induce neutrophil extracellular trap release by human neutrophil granulocytes via FcγRIIIB and Mac-1.
    Journal of immunology (Baltimore, Md. : 1950), 2014, Aug-15, Volume: 193, Issue:4

    Topics: Aminopyrine; Antigen-Antibody Complex; Antioxidants; Ascorbic Acid; Autoimmune Diseases; Butadienes;

2014
Lck Inhibits Heat Shock Protein 65-Mediated Reverse Cholesterol Transport in T Cells.
    Journal of immunology (Baltimore, Md. : 1950), 2016, 11-15, Volume: 197, Issue:10

    Topics: ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; Biologi

2016
Role of Src tyrosine kinase in the atherogenic effects of the 12/15-lipoxygenase pathway in vascular smooth muscle cells.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:3

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Acetylation; Animals; Arachidonate 12-Lipoxygenase; Arac

2009
Characterization of the pattern of the nongenomic signaling pathway through which TCDD-induces early inflammatory responses in U937 human macrophages.
    Chemosphere, 2009, Volume: 74, Issue:11

    Topics: Arachidonic Acid; Aryl Hydrocarbon Receptor Nuclear Translocator; Cell Line; Cyclooxygenase 2; Enzym

2009
Secreted factors from human mast cells trigger inflammatory cytokine production by human airway smooth muscle cells.
    International archives of allergy and immunology, 2013, Volume: 160, Issue:1

    Topics: Asthma; Cell Line; Culture Media, Conditioned; Exosomes; Humans; Imidazoles; Immunoglobulin E; Infla

2013
Arcuate Src activation-induced phosphorylation of NR2B NMDA subunit contributes to inflammatory pain in rats.
    Journal of neurophysiology, 2012, Volume: 108, Issue:11

    Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Freund's Adjuvant; Hot Temperature; Hyp

2012
Modulation of prosurvival signaling in fibroblasts by a protein kinase inhibitor protects against fibrotic tissue injury.
    The American journal of pathology, 2005, Volume: 166, Issue:2

    Topics: Actins; Animals; Bleomycin; Cell Survival; Collagenases; Enzyme Inhibitors; Fibroblasts; Fibrosis; F

2005
Src kinase activates endothelial nitric-oxide synthase by phosphorylating Tyr-83.
    The Journal of biological chemistry, 2005, Oct-28, Volume: 280, Issue:43

    Topics: Animals; Calcium; Cattle; Cells, Cultured; Chlorocebus aethiops; COS Cells; Immunoblotting; Immunopr

2005
Peptidoglycan of Staphylococcus aureus induces enhanced levels of matrix metalloproteinase-9 in human blood originating from neutrophils.
    Shock (Augusta, Ga.), 2005, Volume: 24, Issue:3

    Topics: Chromones; Dose-Response Relationship, Drug; Endotoxemia; Enzyme Inhibitors; Enzyme-Linked Immunosor

2005