ag 1879 has been researched along with Diabetic Nephropathies in 3 studies
3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Taniguchi, K | 1 |
| Xia, L | 1 |
| Goldberg, HJ | 1 |
| Lee, KW | 1 |
| Shah, A | 1 |
| Stavar, L | 1 |
| Masson, EA | 1 |
| Momen, A | 1 |
| Shikatani, EA | 1 |
| John, R | 1 |
| Husain, M | 1 |
| Fantus, IG | 1 |
| Wu, H | 1 |
| Shi, Y | 1 |
| Deng, X | 1 |
| Su, Y | 1 |
| Du, C | 1 |
| Wei, J | 1 |
| Ren, Y | 1 |
| Wu, M | 1 |
| Hou, Y | 1 |
| Duan, H | 1 |
| Mima, A | 1 |
| Matsubara, T | 1 |
| Arai, H | 1 |
| Abe, H | 1 |
| Nagai, K | 1 |
| Kanamori, H | 1 |
| Sumi, E | 1 |
| Takahashi, T | 1 |
| Iehara, N | 1 |
| Fukatsu, A | 1 |
| Kita, T | 1 |
| Doi, T | 1 |
3 other studies available for ag 1879 and Diabetic Nephropathies
| Article | Year |
|---|---|
Inhibition of Src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice.
Topics: ADAM Proteins; ADAM17 Protein; Albuminuria; Animals; Collagen Type IV; Diabetes Mellitus, Experiment | 2013 |
Inhibition of c-Src/p38 MAPK pathway ameliorates renal tubular epithelial cells apoptosis in db/db mice.
Topics: Animals; Apoptosis; Cell Line; Diabetic Nephropathies; Disease Models, Animal; Drug Administration S | 2015 |
Angiotensin II-dependent Src and Smad1 signaling pathway is crucial for the development of diabetic nephropathy.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Butadienes; Cell Line; Collagen Ty | 2006 |