ag 1879 has been researched along with Cystic Fibrosis in 2 studies
3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fiorotto, R | 1 |
| Amenduni, M | 1 |
| Mariotti, V | 1 |
| Fabris, L | 1 |
| Spirli, C | 1 |
| Strazzabosco, M | 1 |
| Valdivieso, ÁG | 1 |
| Clauzure, M | 1 |
| Massip-Copiz, MM | 1 |
| Cancio, CE | 1 |
| Asensio, CJA | 1 |
| Mori, C | 1 |
| Santa-Coloma, TA | 1 |
2 other studies available for ag 1879 and Cystic Fibrosis
| Article | Year |
|---|---|
Src kinase inhibition reduces inflammatory and cytoskeletal changes in ΔF508 human cholangiocytes and improves cystic fibrosis transmembrane conductance regulator correctors efficacy.
Topics: Aminophenols; Aminopyridines; Animals; Benzodioxoles; Biliary Tract; Cell Culture Techniques; Chlori | 2018 |
Impairment of CFTR activity in cultured epithelial cells upregulates the expression and activity of LDH resulting in lactic acid hypersecretion.
Topics: Animals; Anthracenes; Caco-2 Cells; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regul | 2019 |