ag 1879 has been researched along with Colonic Neoplasms in 5 studies
3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metastasizing colon cancer cells bind target tissues primarily via integrins." | 1.33 | Extracellular pressure stimulates tumor cell adhesion in vitro by paxillin activation. ( Basson, MD; Conway, WC; Craig, DH; Thamilselvan, V; van Zyp, Jv; van Zyp, Nv, 2006) |
| "KM12L4A human metastatic colon cancer cells were stably transfected with two distinct kinase-defective mutants of c-src." | 1.32 | Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis. ( Brunton, VG; Cawthorne, C; Dive, C; Frame, MC; Greaves, M; Griffiths, GJ; Koh, MY; Ottley, CJ; Pearson, DG; Reeves, NA; Tilby, MJ; Workman, P, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, A | 1 |
| Ahmad, I | 1 |
| Chhikara, BS | 1 |
| Tiwari, R | 1 |
| Mandal, D | 1 |
| Parang, K | 1 |
| Thamilselvan, V | 2 |
| Basson, MD | 2 |
| Boyd, DD | 1 |
| Wang, H | 1 |
| Avila, H | 1 |
| Parikh, NU | 1 |
| Kessler, H | 1 |
| Magdolen, V | 1 |
| Gallick, GE | 1 |
| Griffiths, GJ | 1 |
| Koh, MY | 1 |
| Brunton, VG | 1 |
| Cawthorne, C | 1 |
| Reeves, NA | 1 |
| Greaves, M | 1 |
| Tilby, MJ | 1 |
| Pearson, DG | 1 |
| Ottley, CJ | 1 |
| Workman, P | 1 |
| Frame, MC | 1 |
| Dive, C | 1 |
| van Zyp, Jv | 1 |
| Conway, WC | 1 |
| Craig, DH | 1 |
| van Zyp, Nv | 1 |
5 other studies available for ag 1879 and Colonic Neoplasms
| Article | Year |
|---|---|
Synthesis of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates and evaluation of their Src kinase inhibitory and anticancer activities.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Fe | 2011 |
Pressure activates colon cancer cell adhesion by inside-out focal adhesion complex and actin cytoskeletal signaling.
Topics: Actins; Animals; Aorta; Cell Adhesion; Cell Membrane; Cells, Cultured; Collagen Type I; Colonic Neop | 2004 |
Combination of an SRC kinase inhibitor with a novel pharmacological antagonist of the urokinase receptor diminishes in vitro colon cancer invasiveness.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blotting, Northern; Blotting, | 2004 |
Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis.
Topics: Apoptosis; bcl-X Protein; Caspase 8; Caspases; Cell Line, Tumor; Colonic Neoplasms; CSK Tyrosine-Pro | 2004 |
Extracellular pressure stimulates tumor cell adhesion in vitro by paxillin activation.
Topics: Adenocarcinoma; Animals; Caco-2 Cells; Cell Adhesion; Cell Line, Tumor; Collagen Type I; Colonic Neo | 2006 |