ag 1879 has been researched along with Cardiac Hypertrophy in 1 studies
3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marin, TM | 1 |
| Clemente, CF | 1 |
| Santos, AM | 1 |
| Picardi, PK | 1 |
| Pascoal, VD | 1 |
| Lopes-Cendes, I | 1 |
| Saad, MJ | 1 |
| Franchini, KG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety and Efficacy of Saracatinib In Subjects With Lymphangioleiomyomatosis[NCT02737202] | Phase 2 | 28 participants (Actual) | Interventional | 2016-04-30 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for ag 1879 and Cardiac Hypertrophy
| Article | Year |
|---|---|
Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways.
Topics: Animals; Animals, Newborn; Cardiomegaly; Cell Size; Cells, Cultured; Extracellular Signal-Regulated | 2008 |